Clinical trials: Liver Ablation
Hepatocellular Carcinoma, Obesity
Central Obesity and Hepatocellular Carcinoma
Recurrence and metastases after microwave ablation(MWA) of hepatocellular carcinoma(HCC) are the major factors that influence the survival.
- Conditions
- Hepatocellular Carcinoma, Obesity, Microwave Ablation
- Trial name
- NCT03082378
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chinese PLA General Hospital
Hepatitis B / Liver Space-occupying Lesions / Patients After Ablation
Radiomics for Diagnosing Liver Diseases and Evaluating Progression
Liver diseases are worldwide problems. liver fibrosis and hepatocellular carcinoma are mostly concerned by clinicians. Radiomcis can improve diagnosis accuracy and evaluate disease progression.
- Trial name
- NCT03221049
- Testing
- radiomics
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Liver Cancer
Pre-procedure Planning for Radiofrequency Ablation Using CT or MR/US Fusion
The purpose of this study is to determine whether fusion technique of pre-radiofrequency ablation (RFA) cross-sectional imaging (CT or MR) and real-time ultrasonography would improve feasibility of RFA in patients with liver…
- Trial name
- NCT02687113
- Testing
- CT/US fusion
- Where
- South Korea
- Volunteers
- 240 people
- Sponsor
- Seoul National University Hospital
Relapsed Pediatric Solid Tumors, Refractory Pediatric Solid Tumors
MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid Tumors
The purpose of this study is to determine if Magnetic Resonance guided High Intensity Focused Ultrasound ablative therapy is safe and feasible for children, adolescents, and young adults with refractory or relapsed solid tumors.
- Conditions
- Relapsed Pediatric Solid Tumors, Refractory Pediatric Solid Tumors, Rhabdomyosarcoma, Ewing Sarcoma
- Trial name
- NCT02076906
- Testing
- Magnetic Resonance High Intensity Focused Ultrasound
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- AeRang Kim
Carcinoma, Hepatocellular
Comparison Between Radiofrequency Versus Ethanol Injection for the Treatment of Hepatocellular Carcinoma
Ethanol injection has been for many years the standard approach as percutaneous treatment of non-surgical early hepatocellular carcinoma in cirrhotic patients.
- Trial name
- NCT00355212
- Testing
- percutaneous ablation of hepatocellular carcinoma
- Where
- Italy
- Volunteers
- 240 people
- Sponsor
- Azienda Ospedaliera San Giovanni Battista
Hepatocellular Carcinoma
Laparoscopic Surgery Versus Radiofrequency Ablation for Recurrent HCC
Hepatocellular carcinoma (HCC) is the fifth most common and the third leading cause of death from cancer worldwide1 . Hepatectomy is still the main effective treatment for HCC accompanying with well-preserved cirrhosis when liver…
- Trial name
- NCT02535117
- Testing
- Laparoscopic Surgery(LS), RFA
- Volunteers
- 216 people
- Sponsor
- Sun Yat-sen University
Radiology, Interventional, Liver Neoplasm
Biliary or Digestive Protection by Room Air Interposition for Thermal Ablation of Central Hepatic Tumors
This study aims to analyse retrospectively the feasibility, the safety, and the efficiency, of biliary or digestive protection with room air interposition for thermal ablation of central liver tumors with high iatrogenic risk.
- Conditions
- Radiology, Interventional, Liver Neoplasm, Carcinoma, Hepatocellular (RENI), Neoplasm Metastasis
- Trial name
- NCT05495529
- Testing
- Thermal Ablation
- Where
- France
- Volunteers
- 61 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Splenomegaly; Congestive, Chronic, Panhematopenia; Splenic
Ultrasound Guided Microwave Ablation of Splenomegaly in Children
Children with liver cirrhosis frequently develops portal hypertension. One of the serious complications to portal hypertension is splenomegaly, which may result in pancytopenia, especially thrombocytopenia that may cause bleeding…
- Conditions
- Splenomegaly; Congestive, Chronic, Panhematopenia; Splenic, Portal Hypertension
- Trial name
- NCT05050994
- Testing
- Microwave ablation
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Karolinska Institutet
Liver Cancer, Surgery
Navigated Laparoscopic Microwave Ablation of Tumor Mimics in Pig Liver - an Ex-vivo Trial
In primary and secondary liver tumors microwave ablation could be an alternative to surgical resection.It could be performed laparoscopically.
- Conditions
- Liver Cancer, Surgery, Navigation, Spatial
- Trial name
- NCT04106453
- Testing
- navigated microwave ablation, ultrasound guided navigation
- Where
- Germany
- Volunteers
- 4 people
- Sponsor
- Universitätsklinikum Köln
Liver Neoplasms
Percutaneous Microwave Ablation Under Ultrasound Guidance for Liver Cancer: a Multicenter Analysis
Ultrasound-guided percutaneous MWA of liver cancer is a relatively new technique with favorable long-term outcomes.Butthe results are mainly from single center reports.A larger scale data need to be analyzed to evaluate the…
- Trial name
- NCT03045952
- Testing
- microwave ablation device
- Where
- China
- Volunteers
- 1,908 people
- Sponsor
- Chinese PLA General Hospital
Hepatocellular Carcinoma, Laser Ablation
Laser Ablation for Intermediate and Advanced Hepatocellular Carcinoma With Portal Vein Tumor Thrombus
Hepatocellular carcinoma (HCC) is the fifth most-common cancer worldwide and the second most-common cause of cancer mortality. Liver resection is the first-line curative treatment for huge HCC.
- Conditions
- Hepatocellular Carcinoma, Laser Ablation, Portal Vein Tumor Thrombus
- Trial name
- NCT02724475
- Testing
- LA, 3D-CRT
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Eastern Hepatobiliary Surgery Hospital
Laparoscopic Cholecystectomy, Liver Ablation
Image Fusion in the OR
The objective of this study is to test the technical feasibility of LapAR visualization system for guiding laparoscopic surgeries and to gather clinical feedback on the use of this tool.
- Trial name
- NCT03670849
- Testing
- LapAR
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Raj Shekhar
Hepatocellular Carcinoma
Computer-assisted Tumor Ablation for Patients With Liver Cancer
In patients with primary liver cancer arising from the liver cells, several treatment options are available according to the stage of the disease.
- Trial name
- NCT03630068
- Testing
- Stereotactic percutaneous image-guided microwave ablation
- Where
- Switzerland
- Volunteers
- 87 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Radiofrequency Ablation, Ultrasonography
Added Value of Contrast-enhanced Ultrasonography for Percutaneous Radiofrequency Ablation
Contrast-enhanced ultrasonography (CEUS)-CT/MRI fusion imaging substantially improved the visibility of small tumors that were inconspicuous on both US and US-CT/MRI fusion imaging, contributing to successful percutaneous…
- Conditions
- Radiofrequency Ablation, Ultrasonography, Liver Tumors
- Trial name
- NCT05445973
- Testing
- Percutaneous Radiofrequency Ablation
- Where
- South Korea
- Volunteers
- 248 people
- Sponsor
- Seoul National University Hospital
Hepatocellular Carcinoma
RFA for Treatment of Intermediate Stage HCC
In Egypt, chronic hepatitis C virus (HCV) is the most prevalent cause of hepatoma. The study aims to evaluate the percutaneous radiofrequency ablation (RFA) efficacy as monotherapy in intermediate versus early-stage…
- Trial name
- NCT05281783
- Testing
- percutaneous radiofrequency ablation (RFA)
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Benha University
Focal Liver Lesions, Ultrasonics
Utility of Ultrasound Imaging for Diagnosis of Focal Liver Lesions: A Radiomics Analysis
Ultrasound (US) as first-line imaging technology in detecting focal liver lesions,also plays a crucial role in evaluating image and guiding ablation which is the main treatment for liver lesions.
- Conditions
- Focal Liver Lesions, Ultrasonics, Intelligent Diagnosis, Ablation
- Trial name
- NCT03871140
- Testing
- diagnosis
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Emphysema, Lung Diseases, Obstructive
Characterization of the Pathobiology of Early Lung Destruction in Alpha 1-Antitrypsin Deficient Individuals
Alpha 1-antitrypsin-deficient individuals develop severe destructive lung disease much earlier and their lung function declines faster than the general population of individuals with chronic obstructive lung disease.
- Conditions
- Emphysema, Lung Diseases, Obstructive, Alpha 1-Antitrypsin Deficiency
- Trial name
- NCT00001462
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Hepatocellular Carcinoma
Trial of Ablation of Small Hepatocellular Carcinomas in Patients of Cirrhosis
The purpose of this study is to assess the efficacy of Radiofrequency ablation (RFA) and percutaneous acetic acid ablation (PAI) in the management of small hepatocellular carcinoma (HCC) in patients of cirrhosis of liver.
- Trial name
- NCT01438437
- Testing
- PAI, RFA
- Where
- India
- Volunteers
- 54 people
- Sponsor
- All India Institute of Medical Sciences
Liver Cancer
A Prospective, Multicenter Clinical Trial of Safety and Effectiveness of Nanosecond Knife Ablation for Liver Cancer
This is a prospective, multi-center, single-arm clinical trial. Four hospitals with national medical clinical trial institution qualifications are selected as clinical trial centers.
- Trial name
- NCT04309747
- Testing
- nanosecond knife liver cancer ablation
- Volunteers
- 190 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Focal Liver Lesions, Contrast-enhanced Ultrasound
Radiomics Analysis of Focal Liver Lesions Based on Contrast-Enhanced Ultrasound Imaging
Contrast-enhanced ultrasound (CEUS) substantially improves the potential of ultrasound (US) for the identification and characterization of focal liver lesions (FLLs).
- Trial name
- NCT04682886
- Testing
- diagnosis
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Ping Liang