Clinical trials: Local; Infection
Surgical Wound Infection
Local Gentamicin Application to Reduce Postoperative Infection Rate
The majority of elderly patients with a displaced fracture of the proximal femur are now treated with a hemiarthroplasty. Prosthetic joint infection is a devastating complication, and the infection rate is high in this group of…
- Trial name
- NCT01287780
- Testing
- Collagen-gentamicin sponge
- Where
- 5 sites in Norway
- Volunteers
- 800 people
- Sponsor
- Oslo University Hospital
Infections, Hospital
Alcohol Hand Gel Use in Mbale Regional Referral Hospital: a Cost Effectiveness Evaluation
Ministry of Health through the National Medical Stores has supplied alcohol-based handgels to the different health facilities in Uganda for the health care providers to use during clinical care.
- Trial name
- WardGel (NCT02435719)
- Where
- Uganda
- Volunteers
- 3,626 people
- Sponsor
- Sanyu Africa Research Institute
Pertussis, Diphtheria
Immunogenicity and Safety of Tetraxim Versus Local DTP + IPV
The present clinical study will assess the immunogenicity and reactogenicity of Sanofi Pasteur's DTaP-IPV combined vaccines as a three-dose primary vaccination at 2, 4 and 6 months of age compared to commercially available…
- Conditions
- Pertussis, Diphtheria, Poliomyelitis, Tetanus
- Trial name
- NCT00319852
- Testing
- DTaP-IPV combined vaccine, DTaP vaccine
- Where
- South Korea
- Volunteers
- 442 people, healthy volunteers welcome
- Sponsor
- Sanofi
Tuberculosis
Local Anesthesia and Tuberculin Skin Test in Infants and Children
The use of local anaesthesia efficiently reduces pain due to needle puncture. However, when tuberculin skin test is performed it is the skin reaction to tuberculin injection that is studied.
- Trial name
- NCT00309673
- Testing
- lidocaine / Prilocaine
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bronchiolitis
Organizational Infrastructure Pediatric Plan in Bronchiolitis Epidemics
Acute bronchiolitis is a frequent respiratory viral infection of infants, responsible for 460,000 new cases per year in France. Over the years, the number of hospitalizations during the epidemic season appears to be increasing.
- Trial name
- OIPP (NCT03663660)
- Testing
- Organizational infrastructure pediatric plan (OIPP)
- Where
- France
- Volunteers
- 1,636 people
- Sponsor
- University Hospital, Montpellier
Lymphoma, Neuroblastoma
Whole-Body MRI and Conventional Imaging in Detecting Distant Metastases in Young Patients With Solid Tumors or Lymphoma
RATIONALE: New imaging procedures, such as whole-body MRI, may improve the ability to detect metastatic cancer and determine the extent of disease.
- Conditions
- Lymphoma, Neuroblastoma, Sarcoma
- Trial name
- NCT00072488
- Testing
- computed tomography, magnetic resonance imaging, positron emission tomography
- Where
- 21 sites in United States, Canada
- Volunteers
- 226 people
- Sponsor
- American College of Radiology Imaging Network
Skin Mycoses
Observational Study of Efficacy and Safety of Travogen Cream and Travocort Cream in the Treatment of Mycoses
An assessment of the efficacy and safety of Travogen cream and Travocort cream in the treatment of local skin mycoses
- Trial name
- NCT00722189
- Where
- Russia
- Volunteers
- 900 people
- Sponsor
- LEO Pharma
Tonsillitis, Hypertrophy
Immune Response To Intranasal Influenza Vaccination
This research during the last decade has focused on the kinetics of the systemic and local immune response to parenteral influenza vaccine in humans.
- Trial name
- NCT01866540
- Testing
- FLUENZ
- Where
- Norway
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Post Operative Pain, Appendicitis
Evaluation of Local Anesthetic at Incision Site
Patient will have usual appendectomy surgery with an injection of local or saline at incision site either before or after the incision at random.
- Trial name
- NCT02483689
- Testing
- Pre Incisional Local Anesthetic, Pre-Incisional Saline, Post-Closure Local Anesthetic
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Valley Anesthesiology Consultants
Immunization; Infection, Educational Problems
Effect of Knowledge on Vaccine Take-up in Adamawa State, Northeastern Nigeria
Child immunization is not a one-time behavior; rather, it is a repeated behavior within a specific timeframe. Not only the low immunization, but also the dropout of immunization and the delayed immunization from the recommended…
- Conditions
- Immunization; Infection, Educational Problems, Information Seeking Behavior
- Trial name
- NCT04042246
- Testing
- Information Provision
- Where
- Nigeria
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Haemophilus Influenzae Type b (Hib) Infection
Immunogenicity and Safety of a Booster Dose of Monovalent Glycoprotein-Conjugated (Diptheria Toxin -CRM197) Hib Vaccine in 365-569 Days Old Healthy Infants
This study will evaluate the safety and immunogenicity of booster dose of two commercially available vaccines used to prevent Haemophilus influenzae type b infections in children 365-569 days of age
- Trial name
- NCT01226953
- Testing
- Haemophilus influenzae type b (Hib) vaccine
- Where
- China
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Anesthesia Intubation Complication, Intubation Complication
A Comparison Of Local Anesthetic Agents And Steroid On Tracheal Tube Cuff
This study aims to compare effects of two different agents on complications due to tracheal tube cuff in pediatric patients. Sore throat, hoarseness, laryngospasm, bronchospasm are the main complications.
- Conditions
- Anesthesia Intubation Complication, Intubation Complication, Sore Throat
- Trial name
- LA-STEROID (NCT04085744)
- Testing
- Lidocaine 10% Spray, Mometasone nasal spray
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people
- Sponsor
- Derince Training and Research Hospital
Primary Care : Suspected and Confirmed Cases of COVID-19, Primary Health Care
Primary Care in AURA for COVID-19
As few data are available on the epidemiology of the COVID-19 in primary care, the project aims to implement a practice-based surveillance network based on multiprofessional health homes in the French region Auvergne-Rhône-Alpes…
- Conditions
- Primary Care : Suspected and Confirmed Cases of COVID-19, Primary Health Care, COVID-19 Pandemic
- Trial name
- SOPRAC (NCT05124145)
- Testing
- No intervention (surveillance system)
- Where
- France
- Volunteers
- 7,000 people
- Sponsor
- Research on Healthcare Performance Lab U1290
Bronchiolitis
The Influence of Inhaled Adrenalin Versus Decongestant as a Local Nasal Treatment in Bronchiolitis
This was a randomized, double blinded, controlled trial. The aim of the study was to compare xylometazoline HCL nasal drops to inhalation of epinephrine as a treatment for bronchiolitis.
- Trial name
- NCT00622817
- Testing
- xylometazoline HCL 0.05%, Epinephrine 1mg
- Volunteers
- 65 people
- Sponsor
- Schneider Children's Medical Center, Israel
Malaria, Falciparum
Artemether/ Lumefantrine: A Study of the Effect of Local Food on Pharmacokinetics and Population Pharmacokinetics
Despite preventive programs, effective case management is still the cornerstone in malaria control. This study is as a strategy towards improved recommendations in resource limited countries during artemether -lumefantrine (AL)…
- Trial name
- NCT01944189
- Testing
- Food
- Where
- Uganda
- Volunteers
- 70 people
- Sponsor
- Makerere University
Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor
Development of Strategies to Increase Enrollment in Clinical Trials for Children With Cancer
RATIONALE: Taking part in a clinical trial may help children with cancer receive more effective treatment. PURPOSE: Determine why patients who are eligible for protocols made available through the Pediatric Oncology Group do not…
- Conditions
- Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor, Extragonadal Germ Cell Tumor, Leukemia
- Trial name
- NCT00002485
- Testing
- psychosocial assessment and care
- Where
- 31 sites in United States, Canada and 2 more
- Volunteers
- 359 people
- Sponsor
- Children's Oncology Group
Childhood Langerhans Cell Histiocytosis, Fanconi Anemia
Umbilical Cord Blood for Stem Cell Transplantation in Treating Young Patients With Malignant or Nonmalignant Diseases
RATIONALE: Umbilical cord blood transplantation may be able to replace immune cells that were destroyed by chemotherapy or radiation therapy.
- Conditions
- Childhood Langerhans Cell Histiocytosis, Fanconi Anemia, Leukemia, Lymphoma
- Trial name
- NCT00084695
- Testing
- anti-thymocyte globulin, busulfan, cyclophosphamide
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Milton S. Hershey Medical Center
Sporotrichosis
Antifungal Agents and Infrared Thermotherapy Alone or in Combination in the Treatment of Sporotrichosis
Sporotrichosis is a chronic granulomatous mycosis caused by sporothrix complex. The course of sporotrichosis is always prolonged and even life-threatening, the treatment of this disease in an important scientific problem to be…
- Trial name
- NCT06300138
- Testing
- Itraconazole, Infrared thermotherapy apparatus, Itraconazole and Infrared thermotherapy apparatus
- Where
- China
- Volunteers
- 150 people
- Sponsor
- First Hospital of China Medical University
Spraying Behavior, Mouth Diseases
Faringomoss Effectiveness in Inhibiting Acute Throat Pain and Discomfort
The purpose of the study was to assess the effectiveness of Faringomoss in reducing the throat discomfort and pain in patients with acute throat diseases and postoperative patients after throat surgeries.
- Conditions
- Spraying Behavior, Mouth Diseases, Throat Diseases, Throat Pain
- Trial name
- NCT02894372
- Testing
- Oral spray 1, Oral spray 2
- Where
- Lithuania
- Volunteers
- 96 people
- Sponsor
- Lithuanian University of Health Sciences
Central Nervous System (CNS) Infection
Local Registry of Central Nervous System Infections (ReCeNSI)
Central Nervous System (CNS) infections are considered rare conditions but at the same time, they are emergencies whose diagnosis and treatment are time-dependent.
- Trial name
- ReCeNSI (NCT07364539)
- Where
- Italy
- Volunteers
- 520 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia