Clinical trials: Local Anesthesia
Postoperative Pain
Bilateral Continuous Erector Spinae Blocks for Post-Sternotomy Pain Management
To evaluate the efficacy of bilateral continuous erector spinae blocks (BESB) for postoperative analgesia in children and adolescents undergoing cardiac surgical procedures via sternotomy in the Early Recovery After Surgery…
- Trial name
- NCT04567407
- Testing
- Bilateral erector spinae blocks using ropivacaine
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Anesthesia, Local
PDL Anesthesia Versus Local Infiltration
The literature concerning the success and pain scores of PDL injection technique compared with other techniques remains controversial; whereas some studies found no significant difference in pain scores between local infiltration…
- Trial name
- PDL (NCT03173898)
- Testing
- PDL anesthesia versus local infiltration
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Analgesia
Postoperative Analgesia by Epidural vs IV Ketamine Concurrent With Caudal Anesthesia in Pediatric Orthopedic Surgery
Preemptive analgesia can improve postoperative pain management. Ketamine may prevent central sensitization during surgery and result in preemptive analgesia.
- Trial name
- NCT00532662
- Testing
- S(+)-ketamine
- Where
- 2 sites in Iran
- Volunteers
- 40 people
- Sponsor
- Tehran University of Medical Sciences
Oral Health Related Quality of Life OHRQoL
Does Treating Early Childhood Caries Under Local or General Anesthesia Have Varying Effects on OHRQoL
A two-arm randomized control trial is to compare the changes in OHRQoL scores among children treated for ECC under general (DGA) and local anesthesia (LA).
- Trial name
- NCT05761691
- Testing
- Dental treatment
- Where
- Saudi Arabia
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Knee Osteoarthritis, Hip Osteoarthritis
Regional Anesthesia in Total Hip and Knee Arthroplasty
The purpose of this study is to test whether the use of Ropivacaine and Mepivacaine are better in terms of effectiveness, cost, and safety than Bupivacaine as regional anesthetics in elective hip or knee replacement surgery.
- Trial name
- NCT04257682
- Testing
- Bupivacaine, Ropivacaine, Mepivacaine
- Volunteers
- 135 people
- Sponsor
- Ottawa Hospital Research Institute
Dental Anxiety, Pain
Efficacy of Tell-Show-Do Behavior-Management Technique During Local Anesthesia in Preschool Children
This will be a randomized, controlled, parallel-group clinical trial. The aim of this study will be to evaluate the effectiveness of "Tell-Show-Do" Behavior Management Technique versus a Conventional technique (covering the…
- Conditions
- Dental Anxiety, Pain, Infant Behavior, Heart Rate and Rhythm Disorders
- Trial name
- NCT02578160
- Testing
- inferior alveolar and lingual nerve block procedure
- Where
- Brazil
- Volunteers
- 52 people
- Sponsor
- Evelyn Alvarez Vidigal
Regional Anesthesia Morbidity, Post Operative Pain
THE EFFICIENCY OF FASCIAL PLANE BLOCKS IN BARIATRIC SURGERY
Bariatric surgery effectively produces weight loss and reduces obesity-related comorbidities. Although it is mostly performed with minimally invasive techniques, the patients may still suffer from moderate-to-severe pain…
- Conditions
- Regional Anesthesia Morbidity, Post Operative Pain, Bariatric Surgery Candidate
- Trial name
- NCT05284695
- Testing
- Bariatric surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 113 people
- Sponsor
- V.K.V. American Hospital, Istanbul
Pain
The Effectiveness of Sweet Solution Versus Cryotherapy in Reducing Pain During Administration of Local Anesthesia Among Children
the porpose of study to assess The Effectiveness of Sweet Solution Versus Cryotherapy in Reducing Pain During Administration of Local Anesthesia Among Children
- Trial name
- NCT07002528
- Testing
- sucrose solution, Cryotherapy, topical anesthesia
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Scoliosis, Spine Deformity
Post-Hoc Cost-Utility Analysis of Ultrasound-Guided Erector Spinae Plane (ESP) Block Versus Total Intravenous Anesthesia (TIVA) in Posterior Scoliosis Correction Surgery: Evidence From the Egyptian EQ-5D-5L Value Set
Posterior scoliosis correction surgery is associated with sever postoperative pain that necessitate high perioperative opioid doses to alleviate pain .
- Trial name
- NCT07470567
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- National Bank Hospital
Anesthesia, Local
Pain Control of Needle-free Versus Needle Injected Local Anesthesia for Pulpotomy of Upper Primary Molars in Children
This is a study that will be conducted on 6 to 8 years old children to compare the needle-less jet injector with the conventional needle attached syringe in terms of efficiency in controlling pain of local anesthetic infiltration…
- Trial name
- NCT03917121
- Testing
- Jet injector, Needle attached dental syringe
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Upper Limb Wound, Lower Limb Wound
Wide-awake Local Anesthesia and no Tourniquet (WALANT) in Plastic Surgery
Wide-awake local anesthesia no tourniquet (WALANT) was proposed and performed in hand operations. Aim of this study is to present the use of WALANT in operations performed on the upper and lower limbs, evaluate its efficacy in…
- Conditions
- Upper Limb Wound, Lower Limb Wound, Anesthesia, Local
- Trial name
- NCT04992351
- Testing
- WALANT
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- University Hospital, Ioannina
Circumcision Adult, Circumcision, Male
Technological Devices in Circumcision
It aims to investigate the effect of circumcision on the pain and anxiety level of children who are circumcised by watching videos/playing games during the procedure.
- Conditions
- Circumcision Adult, Circumcision, Male, Circumcision
- Trial name
- NCT06793722
- Testing
- Technological device in circumcision
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Adiyaman University
Dental Phobia, Dental Anxiety
"Study of Pain Perception Using Computer-Controlled Versus Conventional Local Anaesthesia in Children Undergoing Molar Extraction
This clinical trial aims to compare pain perception in children during dental procedures when using a computer-controlled local anesthesia device versus a traditional syringe.
- Conditions
- Dental Phobia, Dental Anxiety, Dental Anesthesia, Dental Anesthesia Efficacy
- Trial name
- CCLAD-Pain (NCT07056101)
- Testing
- A conventional dental syringe, GENI High-Speed Injection, GENI Moderate-Speed Injection
- Where
- Egypt
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Tarek MHD kher al saka amini
Pain, Infant, Newborn
Intravenous and Topical Analgesics for Procedural Pain in Neonates
This study will test which type of pain medication is best for the management of pain in newborn preterm and full-term infants having a deep intravenous cannula inserted.
- Trial name
- NCT00213200
- Testing
- morphine, amethocaine
- Where
- 2 sites in Canada
- Volunteers
- 108 people
- Sponsor
- The Hospital for Sick Children
Pain, Postoperative
Bilateral Paravertebral Blockade (T7-10) vs. Incisional Local Anesthetic Administration for Pediatric Patients
The objective of this study is to assess the efficacy of paravertebral nerve blocks, single shot, with ropivacaine 0.5% for postoperative pain control after elective laparoscopic cholecystectomy as compared with incisional…
- Trial name
- NCT01380834
- Testing
- control group, treatment group
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Mihaela Visoiu
Behavior, Child, Dental Anxiety
Pain and Anxiety Reduction Using a Vibrating Eye Massage Device With Relaxing Nature Sounds
This study aims to evaluate the effectiveness and acceptance of an eye massage device that produces nature sounds and vibratory stimulations in the management of anxious pediatric patients during inferior alveolar nerve block…
- Conditions
- Behavior, Child, Dental Anxiety, Anesthesia, Local
- Trial name
- NCT05592587
- Testing
- Evaluation of the effectiveness of eye massage device producing both vibrations and nature sounds distraction in the management of anxious pediatric patients during inferior alveolar nerve., Evaluation of the effectiveness of eye massage device producing vibratory stimulations distraction in the management of anxious pediatric patients during inferior alveolar nerve., Evaluation of the effectiveness of basic behavior guidance techniques without using any type of distraction aids in the management of anxious pediatric patients during inferior alveolar nerve.
- Where
- Syria
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Damascus University
Colonic Diseases, Post-operative Pain
Local Anaesthesia Used During Fast-track Colonic Surgery: Evaluation of Bupivacaine and Levobupivacaine in Practice
The standard treatment for post operative pain is now bupivacaine + sufentanil. The use of this combination during fast-track colonic surgery leads frequently to post-operative nausea and vomiting and limited mobilisation…
- Conditions
- Colonic Diseases, Post-operative Pain, Local Anesthesia
- Trial name
- NCT01105442
- Where
- Netherlands
- Volunteers
- 14 people
- Sponsor
- Martini Hospital Groningen
Local Anesthetic Complication
Comparative Effect of Palatal Injection in Pediatric Patient
The aim of this study is to compare the pain perception of pediatric patients during extraction with and without palatal injection and to show whether articaine HCl and lidocaine HCl can provide palatal anesthesia in maxillary…
- Trial name
- NCT06025825
- Testing
- Articaine Hydrochloride + Epinephrine, Lidocaine Hydrochloride + Epinephrine
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Ankara Yildirim Beyazıt University
Pain, Postoperative
Blood Ropivacaine Concentrations Following Chest Wall Nerve Block Continuous Infusion
The main objective of this proposed investigation is to evaluate blood ropivacaine concentrations in infants and toddlers following the initiation of, and over the course of, continuous paravertebral nerve blockade using…
- Trial name
- NCT02860091
- Testing
- Ropivacaine infusion
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Boston Children's Hospital
Congenital Heart Defect, Congenital Heart Disease
Regional Anesthesia for Cardiothoracic Enhanced Recovery (RACER) Study
The erector spinae plane block is a novel regional anesthetic technique that allows for analgesia of the thorax and abdomen with a peripheral nerve block.
- Conditions
- Congenital Heart Defect, Congenital Heart Disease, Anesthesia, Local, Opioid Use
- Trial name
- NCT03611374
- Testing
- Bilateral Erector Spinae Plane Block (ESPB)
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Stanford University