Clinical trials: Lock Solution
Bacteremia
Central Venous Catheter Lock Solution
The purpose of this study is to determine whether the application of 47% citrate lock solution decreases the incidence of infection and thrombosis of central venous catheter in hemodialysis population.
- Trial name
- CVCLS (NCT00862966)
- Testing
- citrate, heparin
- Where
- Bosnia and Herzegovina
- Volunteers
- 40 people
- Sponsor
- University Medical Center, Tuzla
Central Line Complication, Central Line-associated Bloodstream Infection (CLABSI)
Compassionate-Use of 4% T-EDTA Lock Solution for Central Venous Lines of Pediatric PN Patients
In this research study we want to learn more about a study drug, tetrasodium sodium EDTA (Kitelock™) for maintaining the patency (blood flow) through a central venous catheter.
- Trial name
- NCT04559334
- Testing
- Tetrasodium EDTA Catheter Lock Solution
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Boston Children's Hospital
Blood Stream Infections, Short Bowel Syndrome
Evaluation of 70% Ethanol Lock Solution to Prevent Catheter Related Blood Stream Infections in Pediatric Patients
The purpose of this study is to evaluate the clinical practice of the prophylactic use of ethanol locks for the prevention of catheter related blood stream infections in pediatric intestinal rehabilitation program patients…
- Trial name
- NCT01409772
- Testing
- Ethanol Lock
- Sponsor
- University of Nebraska
Catheter-related Bloodstream Infection, Preterm
Lock sOlutiOnS for Epicutaneo-caval Catheters in Neonates: a "LOOSEN" Pilot Study
Epicutaneo-caval catheters (ECCs) are widely used in neonatal intensive care units (NICUs). They are small catheters inserted via superficial veins of the limbs or scalp using direct vein visualization The pathogenic…
- Conditions
- Catheter-related Bloodstream Infection, Preterm, Catheter Infection, Catheter Complications
- Trial name
- LOOSEN (NCT05729321)
- Testing
- neutrox
- Where
- 2 sites in Italy
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Pediatric Intestinal Failure
KiteLock 4% EDTA Lock Solution for the Prevention of Occlusions in Children With Intestinal Failure
A multi-site, randomized, 2-arm open-label trial to determine if 4% Tetrasodium (EDTA) catheter lock solution is more effective than heparin lock (standard of care) in preventing central venous catheter occlusions in children…
- Trial name
- NCT05879835
- Testing
- KiteLock 4% Sterile Catheter Lock Solution, Heparin Lock Solution
- Where
- 8 sites in United States
- Volunteers
- 124 people
- Sponsor
- SterileCare Inc.
Bacteremia, Neoplasms
Taurolidine Lock Solution in the Prevention of Catheter Related Bacteremia
Children with cancer need a long term tunnelled central venous catheter (TCVC) for the entire duration of their treatment. TCVCs are locked with heparin when not in use.
- Trial name
- NCT00735813
- Testing
- Taurolock, Heparin
- Where
- Denmark
- Volunteers
- 129 people
- Sponsor
- Aarhus University Hospital
End Stage Renal Disease, Hemodialysis
Addition of Heparin to Taurolock-TM CLS in HD Patients With TCC Dose it Improve Catheter Patency Problems ?
Addition of Heparin to the Catheter Lock Solution (CLS): Taurolock-TM will improve the vascular patency compared to Taurolock-TM alone , in hemodialysis patients with Tunneled Cuffed Catheter(TCC) as vascular access.
- Trial name
- NCT00749619
- Testing
- Catheter Lock Solution Taurolidine and Citrate, Catheter Lock Solution :Taurolidine and Citrate and Heparin, Catheter Lock Solution : Heparin
- Where
- Israel
- Sponsor
- Western Galilee Hospital-Nahariya
Catheter Related Blood Stream Infection, Hemodialysis
Antimicrobial Locks for Hemodialysis Catheter Infections
Tunneled hemodialysis catheters are susceptible to infection with high incidence of complication to the hemodialysis patients .The study aimed to prevent catheter infection through comparing use of antimicrobial solution…
- Conditions
- Catheter Related Blood Stream Infection, Hemodialysis, Vascular Access
- Trial name
- NCT07074821
- Testing
- Taurolidine citrate 4% and heparin 500
- Where
- Oman
- Volunteers
- 100 people
- Sponsor
- Oman Ministry of Health
Central Line-associated Bloodstream Infection (CLABSI)
Central Line-associated Bloodstream Infection Prevention Using TauroLock-Hep100 in Pediatric Oncology Patients.
The goal of this assessor blinded randomized controlled trial is to compare a lock solution containing taurolidine, citrate and heparin to a heparin only lock solution for the prevention of central line associated bloodstream…
- Trial name
- CATERPILLAR (NCT05740150)
- Testing
- TauroLock-Hep100 (taurolidine 1.35%, citrate 4%, heparin 100 IU/mL), Heparin lock (heparin 100 IU/mL)
- Where
- Netherlands
- Volunteers
- 462 people
- Sponsor
- Princess Maxima Center for Pediatric Oncology