Clinical trials: Locomotion
Parkinson's Disease
Effects of Exercise on Long-Range Autocorrelations in Parkinson's Disease
Parkinson's disease (PD) is one of the most common neurodegenerative disorders. The parkinsonian gait is characterized by reducted stride length and gait speed, postural disorders (with a high risk of falling) and a modification…
- Trial name
- NCT02419768
- Testing
- Physical Exercise
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Cerebral Palsy, Spastic
Associated Disorders of Locomotion and Postural Control of Axial Segments in Cerebral Palsy
Gait abnormalities, which occur in Cerebral Palsy (CP), are characterized usually by a toe-to-floor or a plantar-to-floor initial contact (equinus gait), followed by an early braking of the tibia's forward progression (during…
- Trial name
- NCT04287673
- Testing
- Rehabilitation involving strongly the trunk
- Where
- France
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est
Young Children With Motor Disabilities
Using Head-mounted, Eye-tracking to Compare Looking, Manual Exploration and Social Interaction During Active Locomotion
The three purposes of this study are: 1) to determine the feasibility of using a head-mounted eye-tracker and examine the effects of the optimal mobility training on increasing visual and manual exploration in toddlers with…
- Trial name
- NCT05441137
- Testing
- Ride-On Cars Training with Different Postures, Conventional Therapy
- Where
- 2 sites in Taiwan
- Volunteers
- 72 people
- Sponsor
- Chang Gung Memorial Hospital
Premature Birth
EEG and NIRS in Preterm Infants
Experimental cross-sectional study of a single application (vojta therapy or massage) in preterm and non-preterm infants to test whether there are differences in brain activation and oxygenation that occur with both techniques…
- Trial name
- NCT05410340
- Testing
- Vojta Therapy, Massotherapy
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
CP, Gait Disorders, Neurologic
Retention of Whole-body Training Effects on Ambulatory Function in Children With Cerebral Palsy
This study will evaluate the retention effects of a four-week whole-body vibration training intervention in children with Cerebral Palsy.
- Conditions
- CP, Gait Disorders, Neurologic, Locomotion Disorder, Neurologic
- Trial name
- CP_WBVT (NCT04961749)
- Testing
- Whole body vibration training
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Texas, El Paso
Central Nervous System Diseases
The Effect of Craniosacral Therapy as Additive Procedure.
This observational, retrospective study has shown, that the addition of craniosacral therapy to the Vojta method has improved the effects of the therapy in 6 months follow-up period.
- Trial name
- COREHNERV (NCT05722756)
- Testing
- craniosacral therapy
- Volunteers
- 51 people
- Sponsor
- Wroclaw Medical University
SMA
A Head-to-head Study Comparing the Functional Value of Two Models of Robotically Assisted Rehabilitation in SMA (Spinal Muscular Atrophy) Patients
A head-to-head study comparing the functional value of two models of robotically assisted rehabilitation in patients with SMA. A single-center, randomized, single-blinded, comparative study of Robotically Assisted Verticalization…
- Trial name
- SMArt (NCT06322654)
- Testing
- Robotically Assisted Locomotion, Robotically Assisted Verticalization
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Wiktor Dega University Orthopedic and Rehabilitation Hospital
Spinal Cord Injury
Comparison of Post-pinal Cord Injury (SCI) Locomotor Training Techniques
Background: Body weight supported (BWS) locomotor training improves overground walking ability in individuals with motor-incomplete spinal cord injury (SCI).
- Trial name
- NCT01095380
- Testing
- Locomotor training
- Volunteers
- 74 people
- Sponsor
- University of Miami
Spinal Cord Injury, Spinal Cord Injury Subacute
Spinal Stimulation With Gait Training to Improve Lower Limbs Motor Recovery in Spinal Cord Injury
Spinal cord injury (SCI) often results in partial or complete loss of movement. In the subacute phase (< 6 months), the central nervous system shows increased potential for neuroplasticity, making it more responsive to…
- Conditions
- Spinal Cord Injury, Spinal Cord Injury Subacute, Locomotion, Gait Disorder, Sensorimotor
- Trial name
- CIMELocomotion (NCT07375745)
- Testing
- Protocol 2: Gait training combined with an effective tSCS
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal
Prematurity, Extreme Prematurity
Early Intervention Based on Neonatal Crawling in Very Premature Infants at Risk For Neurodevelopmental Disorder
Extreme prematurity is constantly increasing according to the World Health Organization. However, methods to train premature infants at risk of disability is sorely lacking. The goal of this project is to overcome this problem.
- Conditions
- Prematurity, Extreme Prematurity, Infant Development, Brain Damage
- Trial name
- Premalocom2 (NCT06027645)
- Testing
- Crawling stimulation with a mini-skateboard (i.e. the crawliskate)
- Where
- 3 sites in France
- Volunteers
- 50 people
- Sponsor
- Marianne Barbu-Roth
Cerebral Palsy
Analysis of the Psychometric Properties of Kinematic Parameters of Locomotion Measured by Inertial Measurement Units. Validation in Healthy Children and Children With Cerebral Palsy
Cerebral palsy (CP) is currently one of the major causes of disability in children. The presence of various disorders (muscle stiffness, architectural bone defects, spasticity) leads to a number of functional impacts, including…
- Trial name
- KAPP-IMU anc (NCT06138925)
- Testing
- Analysis of walking, Analysis of running
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Spinal Cord Injury
Treadmill Training With Body Weight Support in Patients With Spinal Cord Injury
Body weight support (BWS) treadmill training uses an overhead harness to give partial support to patients walking on a treadmill.
- Trial name
- NCT00061295
- Testing
- Body weight support treadmill training
- Where
- United States
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
CP (Cerebral Palsy), Diplegia
Static and Dynamic Postural Stability in Cerebral Palsy Children
Cerebral palsy (CP) concerns 2 children out of 1000 in the general population (SCPE 2002). It is the main cause of postural and motor deficits in children.
- Conditions
- CP (Cerebral Palsy), Diplegia, Hemiplegia, Postural; Defect
- Trial name
- Dual-Task (NCT01799304)
- Testing
- no distractor control group, visual and sound attentional distractors, sound attentional distractor alone
- Where
- France
- Volunteers
- 24 people
- Sponsor
- University Hospital, Grenoble
Capsule Endoscopy
Active Locomotion of Magnetically Controlled Capsule Endoscopy in the Small Bowel: A Feasibility Study
The aim of this study is to evaluate the responsiveness of the capsule endoscope to the attitude controller and to investigate its active locomotion performance within the small bowel.
- Trial name
- NCT07325344
- Testing
- magnetic control
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Shandong University
Motor Skills, Locomotor Activity
Effects of Neuromuscular Exercises on Motor Skills in Girls
This randomized controlled trial found that integrative neuromuscular exercises significantly improved gross motor skills in school-age girls compared to regular physical activity.
- Conditions
- Motor Skills, Locomotor Activity, Objective Control Skills
- Trial name
- MOVE-Girls (NCT07491666)
- Testing
- Training program
- Where
- Serbia
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of Novi Sad
Brain Concussion, Musculoskeletal Injury
A Sports Injury Prevention Program to Reduce Subsequent Injuries After Concussion
The long-term goal of this research is to implement methods that healthcare providers can use across diverse clinical settings to (1) identify athletes at risk for (musculoskeletal) MSK injury when cleared to return to play (RTP)…
- Conditions
- Brain Concussion, Musculoskeletal Injury, Locomotion, Postural Balance
- Trial name
- NCT03917290
- Testing
- Neuromuscular training
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Colorado, Denver
Healthy
Nerve Stimulation to Modify a Spinal Reflex
This study will determine whether stimulating the nerves or the brain can modify the spinal reflex that controls the muscles that flex and extend the ankle.
- Trial name
- NCT00039819
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Obesity and Overweight
Effect of Simulated Weight Loss on the Energy Cost of Locomotion in Overweight or Obese Adolescents
Current literature suggests that part of the energy response to weight loss is not due to changes in fat mass and lean mass, but rather to a homeostatic adaptation aimed at limiting or even preventing weight loss and preserving…
- Trial name
- DELOAD (NCT07155746)
- Testing
- Incremental walking exercise on an AlterG treadmill (anti-gravity)
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Emile Roux
Brain Concussion
Examination of Balance, Vestibular, and Ocular Functions and Activity Following Concussion
Previous research and position statements have outlined the necessity of balance and gait testing in the post-concussion evaluation of athletes.
- Trial name
- NCT02317107
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Spinal Cord Injury (SCI)
Restoring Walking in Non-ambulatory Children With Severe Chronic Spinal Cord Injury (SCI) (Kids STEP Study)
The Kids STEP Study aims to 1. Determine if walking can be restored in children with incomplete SCI and little to no leg movement 2. Identify the neural pathways that permit recovery of walking
- Trial name
- NCT00488280
- Testing
- Locomotor Training
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Florida