Clinical trials: Locoregional Anaesthesia
Anesthesia, Local
Lidocaine Administration Using STAR Particles
This study is being done to answer the question: Do STAR particles (tiny pieces of ceramic with small spikes) help numbing gel (a gel that helps you feel less pain) work more quickly to provide local anesthesia or numbing in a…
- Trial name
- NCT06034340
- Testing
- LET Gel after STAR Particle Application (Right or Left Arm), LET Gel Application without STAR Particle Application (Contralateral Arm)
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Emory University
Hydrocephalus in Children, Regional Block
Scalp Blocks for Pediatric External Ventricular Drainage Placement
External ventricular drainage (EVD) provides cerebrospinal fluid drainage in hydrocephalus. In adults, the neurosurgeon can place EVD at the bedside.
- Conditions
- Hydrocephalus in Children, Regional Block, Pediatric Anesthesia
- Trial name
- NCT06903598
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Hande Gurbuz
Spinal Anesthesia, Local Anesthetic
Age-Based and Weight-Based Bupivacaine Dosing for Pediatric Spinal Anesthesia for Elective Infra-Umbilical Surgeries
Pediatric anesthesia presents distinctive challenges, particularly concerning appropriate dosage administration of local anesthetics for spinal anesthesia (SA).
- Conditions
- Spinal Anesthesia, Local Anesthetic, Bupivacaine
- Trial name
- NCT06801600
- Testing
- Weight-based dosing, Age-based dosing
- Volunteers
- 60 people
- Sponsor
- Cairo University
Sevoflurane Consumption
Pre-emptive Local Anesthesia and Sevoflurane Consumption in Pediatric Dental Anesthesia
This study will evaluate whether pre-emptive local anesthesia reduces sevoflurane consumption during pediatric day-case dental treatment performed under general anesthesia.
- Trial name
- PEDSEVOLA (NCT07608900)
- Testing
- Pre-emptive Local Anesthesia, Articaine With Epinephrine, Sevoflurane
- Volunteers
- 80 people
- Sponsor
- TC Erciyes University
Postoperative Pain Management, Penile Surgery-Related Pain
Anatomical Measurements of Pudendal Nerve Block in Children
This prospective observational study aims to investigate the relationship between anatomical parameters-specifically the distance from the anus to the needle insertion point and the depth required to reach the pudendal…
- Trial name
- NCT07348029
- Testing
- Neurostimulation-Guided Pudendal Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University - Cerrahpasa
Postoperative Pain
Bilateral Continuous Erector Spinae Blocks for Post-Sternotomy Pain Management
To evaluate the efficacy of bilateral continuous erector spinae blocks (BESB) for postoperative analgesia in children and adolescents undergoing cardiac surgical procedures via sternotomy in the Early Recovery After Surgery…
- Trial name
- NCT04567407
- Testing
- Bilateral erector spinae blocks using ropivacaine
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Pectus Excavatum, Chest Deformities
SPSIPB Versus SAPB for Postoperative Analgesia After Minimally Invasive Repair of Pectus Excavatum
This prospective observational cohort study will compare postoperative analgesic outcomes in patients undergoing minimally invasive repair of pectus excavatum.
- Trial name
- NCT07697222
- Testing
- Postoperative Analgesia Protocol, Bispectral Index Monitoring, Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Marmara University
Congenital Heart Disease
Effect of Local Warming for Arterial Catheterization in Pediatric Anesthesia
The increase in internal diameter (ID) and cross-sectional area (CSA) may facilitate better arterial catheterization. Since an increase in body temperature can cause peripheral vasodilation, we aimed to determine if local warming…
- Trial name
- WARM-PA (NCT06041685)
- Testing
- local warming
- Where
- South Korea
- Volunteers
- 126 people
- Sponsor
- Pusan National University Yangsan Hospital
Nerve Block, Hip Fracture Surgeries
Self-Guided Immersive Virtual Reality Versus Mannequin-based Simulators to Teach the Ultrasound-Guided Supra-Inguinal Fascia Iliaca Block
This research project aims to see if using immersive virtual reality (iVR) is as good as using traditional mannequins to teach medical staff how to perform a specific nerve block called an ultrasound-guided supra-inguinal fascia…
- Trial name
- NCT07035015
- Testing
- VR UGRA, Mannequin-based simulation
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- The Ottawa Hospital
Pediatrics, Anesthesia, Local
Validation of Peripheral Perfusion Index in Predicting Successful Supraclavicular Brachial Plexus Block in Pediatrics
Few data are available for the PI as a tool for evaluation of peripheral block success in pediatric patients. Furthermore, there is currently no cut-off value defined for the accuracy of the PI in the detection of successful…
- Trial name
- NCT05815563
- Where
- Egypt
- Volunteers
- 59 people
- Sponsor
- Cairo University
Dental Anxiety, Pain Management
Effectiveness of Virtual Reality Technique on Children
Studying the effect of using virtual reality technique in managing pain, anxiety, and vital signs among pediatric dental patients.
- Conditions
- Dental Anxiety, Pain Management, Pediatric Dentistry
- Trial name
- NCT07722221
- Testing
- Conventional, Virtual reality
- Where
- Syria
- Volunteers
- 64 people
- Sponsor
- Latakia University
Pain, Postoperative Pain
Comparison of Post-Operative Analgesia After Percutaneous Nephrolithotomy.
The rationale of this study was to compare the efficacy of peri-tract bupivacaine infiltration with intravenous post-operative analgesia following PCNL in reference to the context with the previous studies so that we can adopt…
- Trial name
- NCT04835116
- Testing
- Bupivacaine Hydrochloride 0.25% Injection. Paracetamol 650mg. Orphenadrine 50mg., paracetamol 1000mg. Tramadol 50mg. Dimenhydrinate 50mg.
- Where
- Pakistan
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Urology, Rawalpindi
Surgery
Evaluation of the Use of RELAX Glasses on Anxiety of Patients Undergoing Dental Extraction > 2 Teeth, Under Local Anesthesia, Compared With Those Not Using Glasses
The vast majority of tooth extraction surgery is performed under local anaesthetic, and can be a source of anxiety. In their 2015 article, Appukuttan et al studied the anxiety felt by 1148 patients prior to tooth extraction, and…
- Trial name
- BRIGAND (NCT06589908)
- Testing
- RELAX glasses
- Where
- France
- Volunteers
- 106 people
- Sponsor
- Centre Hospitalier de Valenciennes
Regional Anesthesia, Postoperative Pain, Acute
Caudal Block and Transversus Abdominis Plane Block in Pediatric Inguinal Hernia Repair
Pediatric inguinal hernia repair (IHR) candidates experiences ordinarily mild to moderate pain, rarely severe pain in the postoperative period.
- Trial name
- NCT05286190
- Testing
- Bupivacaine 0.25% Injectable Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Ropivacaine, Laparoscopic Cholecystectomy
Ropivacaine Use Intraincisionally Versus Intraperitoneally for Post-Laparoscopic Cholecystectomy Pain
Pain still remains a limiting factor in early discharge of patients undergoing laparoscopic cholecystectomy. Almost all earlier studies done to compare the efficacy of local anaesthetics used intraperitoneally as compared to…
- Conditions
- Ropivacaine, Laparoscopic Cholecystectomy, Pain
- Trial name
- NCT03265223
- Testing
- 0.2% ropivacaine
- Volunteers
- 353 people
- Sponsor
- Jawaharlal Nehru Medical College
Stroke, TIA
A New Oxygen Mask for Carotid Endarterectomy Under Local Anaesthesia
The purpose of this study is to determine the effectiveness of oxygenation and patient-acceptability of a novel oxygen face mask in patients undergoing carotid endarterectomies (CEAs).
- Conditions
- Stroke, TIA, Surgery, Anaesthesia
- Trial name
- NCT01064908
- Testing
- OxyMask
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- Brighton and Sussex University Hospitals NHS Trust
Local Anesthesia Injection Pain
Evaluation of Computer-controlled Local Anesthesia in Children - a Clinical Trial
The goal of this clinical trial is to learn if Computer Controlled Local Anesthetic Delivery (CCLAD) results in lower pain during local anesthesia administration for infiltration in the buccal region of the upper jaw in patients…
- Trial name
- NCT06785480
- Testing
- Computer Controlled Local Anesthetic Delivery (CCLAD), Conventional metallic syringe
- Where
- Belgium
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Local Anesthetic
Efficacy and Safety of Chloroprocaine 3% Gel and Oxybuprocaine 0.4% Eye Drops Anesthesia in Pediatric Population
The goal of this clinical trial is to assess the efficacy and safety of Chloroprocaine 3% eye gel compared to Oxybuprocaine 0,4% eye drops when used for inducing ocular surface anesthesia in pediatric patients.
- Trial name
- NCT05926258
- Testing
- Chloroprocaine 3% eye gel, Oxybuprocaine Hydrochloride 4 Mg/mL Eye Drops
- Where
- 3 sites in Italy
- Volunteers
- 74 people
- Sponsor
- Sintetica SA
Urinary Catheters, Retention, Urinary
Evaluation of a Novel Medical Device to Facilitate Gel Instillation During Change of Long-term Urinary Catheters
A randomized, open label, controlled, parallel group study to investigate difference between regional standard procedure and a novel modified procedure (using an additional novel device to facilitate gel installation) for…
- Conditions
- Urinary Catheters, Retention, Urinary, Incontinence, Urinary, Anesthesia, Local
- Trial name
- NCT03289117
- Testing
- Novel gel installation device procedure, Standard procedure
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Region Skane
Complications; Cesarean Section, Hypotension
Extra Sitting Time After Spinal Anesthesia for Cesarean Section and Fetal Well-being
After injection of the spinal anesthetic drug, women will be allowed to lie down immediately (0-30 sec) or after three minutes (180 sec) of sitting.
- Trial name
- NCT02893696
- Testing
- Various sitting time
- Where
- United States
- Sponsor
- University of Texas Southwestern Medical Center