Clinical trials: Long Term Antibiotics
Antibiotic Initiation, Antibiotic Duration
Feedback to Improve Rational Strategies of Antibiotic Initiation and Duration in Long Term Care (FIRST AID -LTC) - Phase 2
There is a high rate of inappropriate antibiotic use in LTC facilities, with both unnecessary initiation and prolongation of treatments.
- Trial name
- FIRST AID-LTC (NCT04187742)
- Testing
- Social Comparison Email vs. Standard Email, Maintenance Certification Email vs. Standard Email, Report Opening Status Email vs. Standard Email (among previous report openers and non-openers)
- Where
- Canada
- Volunteers
- 421 people
- Sponsor
- Institute for Clinical Evaluative Sciences
Cystic Fibrosis
Extension Study of Liposomal Amikacin for Inhalation in Cystic Fibrosis (CF) Patients With Chronic Pseudomonas Aeruginosa (Pa) Infection
The purpose of this study is to evaluate the long term safety and tolerability of Liposomal Amikacin for Inhalation (LAI) 590 mg once daily (QD) in Cystic Fibrosis patients with chronic infection due to pseudomonas aeruginosa.
- Trial name
- NCT01316276
- Testing
- Liposomal amikacin for inhalation
- Where
- 50 sites in Austria, Belgium and 15 more
- Volunteers
- 206 people
- Sponsor
- Insmed Incorporated
Meningitis, Bacterial Infections
Prospective Clinical Registry of Acute Treatment and Long-term Assessment of Children Meningitis
Prospective, multicenter, observational clinical registry of pediatric patients with acute infectious meningitis across approximately 20 public and private hospitals in Brazil.
- Conditions
- Meningitis, Bacterial Infections, Viral Meningitis, Fungal Meningitis
- Trial name
- ATLAS-II (NCT07062445)
- Where
- Brazil
- Volunteers
- 600 people
- Sponsor
- Hospital Israelita Albert Einstein
Lower Abdominal Pain, Right Iliac Fossa Pain
Non Operative Treatment for Acute Appendicitis
Case control studies that randomly assign patients to either surgical or non-surgical treatment yield a relapse rate of approximately 14% at one year.
- Conditions
- Lower Abdominal Pain, Right Iliac Fossa Pain, Acute Appendicitis
- Trial name
- NOTA (NCT01096927)
- Testing
- Amoxicillin and Clavulanic Acid
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- Maggiore Bellaria Hospital, Bologna
Gingival Diseases, Caries
Short- and Long Term Antibacterial Effects of a Single Rinse With Different Mouthwashes: a Randomized Clinical Trial
Objectives: To reduce the microbial level in the aerosol created during dental procedures is essential in avoiding infections. The aim of this study was to examine the change of Streptococcus mutans (S.
- Trial name
- NCT05178823
- Testing
- Chlorhexidine mouthwash
- Where
- Hungary
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Infectious Diseases
BAY 0 9867 Cipro Pediatric Use Study (QUIP)
Objective and subjective musculoskeletal evaluations will be performed to determine differences in the ciprofloxacin versus non-quinolone treated pediatric patients so that we can tell what the natural occurrence of such…
- Trial name
- NCT00761462
- Testing
- Ciprofloxacin, Non-quinolone antibiotic
- Where
- 67 sites in United States, Canada
- Volunteers
- 1,029 people
- Sponsor
- Bayer
Pulmonary Infections, Pseudomonas Aeruginosa in Cystic Fibrosis
Long Term Safety of Tobramycin Inhalation Powder in Patients With Cystic Fibrosis
This study assessed the long term safety data for the use of tobramycin inhalation powder in patients suffering from cystic fibrosis who have a chronic pulmonary infection with Pseudomonas aeruginosa.
- Trial name
- NCT01519661
- Testing
- TBM100
- Where
- 49 sites in United States, Argentina and 8 more
- Volunteers
- 157 people
- Sponsor
- Novartis Pharmaceuticals
Pyelonephritis
Short-term Antibiotic Therapy for Pyelonephritis in Childhood
The purpose of this study is to evaluate the efficacy of oral ceftibuten for 7 days versus 10 days in acute pyelonephritis in children.
- Trial name
- STUTI (NCT00724256)
- Testing
- ceftibuten
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- IRCCS Burlo Garofolo
Otitis Media
Long-term Antibiotics for Treatment and Prevention of Otitis Media in Aborignal Children
This clinical trial was conducted in a population where tympanic membrane perforation occurs in 60% infants in the first year of life.
- Trial name
- COMIT1 (NCT00539149)
- Testing
- Amoxycillin
- Where
- Australia
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Menzies School of Health Research
Respiratory Tract Infections
Long Term Effect of General Practitioner Education on Antibiotic Prescribing
Respiratory tract infections are the most common indication for antibiotic prescribing in primary care. Several studies have shown a strong relationship between antibiotic use and bacterial resistance.
- Trial name
- PAAIR2 (NCT01107223)
- Testing
- Experimental: Training to antibiotic prescription, No education on antibiotic prescription rules.
- Where
- France
- Volunteers
- 170 people
- Sponsor
- Henri Mondor University Hospital
Ceserean Section, Lower Limb Fractures
Infection Prevention for "Bellwether" Surgery in Ethiopia
The study examines surgical site infections and antimicrobial resistance following life-saving surgeries like C-sections and leg fracture repairs in Ethiopia.
- Conditions
- Ceserean Section, Lower Limb Fractures, Surgical Site Infection (SSI)
- Trial name
- NCT07647796
- Testing
- Surgical Site Infection Prevention and Control (IPC) Bundle
- Where
- Ethiopia
- Volunteers
- 1,000 people
- Sponsor
- Karolinska Institutet
Mycobacterium Avium-intracellulare Infection, HIV Infections
Long-Term Assessment for Metabolic, Cardiovascular and Neurologic Problems in HIV-Infected Patients With Increased CD4 Cells Counts Following Anti-HIV Therapy
The purpose of this study is to see if there are any changes in sugar and fat levels in the blood when patients take anti-HIV therapy for many years.
- Trial name
- NCT00000883
- Testing
- Azithromycin
- Where
- 51 sites in United States
- Volunteers
- 636 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Urinary Tract Infection, Antibiotic Use
Optimizing Antibiotic Use in Long Term Care
The purpose of this study was to determine if a multi-faceted intervention to implement diagnostic and therapeutic algorithms for management of suspected urinary infection in nursing home residents could reduce antibiotic…
- Trial name
- NCT00243360
- Testing
- diagnostic and treatment clinical algorithms
- Where
- Canada
- Sponsor
- Agency for Healthcare Research and Quality (AHRQ)
Antibiotic Initiation, Antibiotic Duration
Feedback to Improve Rational Strategies of Antibiotic Initiation and Duration in Long Term Care
There is a high rate of inappropriate antibiotic use in long-term care (LTC) facilities, with both unnecessary initiation and prolongation of treatments.
- Trial name
- FIRST AID-LTC (NCT03807466)
- Testing
- Dynamic/Interactive vs. Static/Paginated Report, LTC Physicians Enrolled vs. Not Enrolled in Reports
- Where
- Canada
- Volunteers
- 356 people
- Sponsor
- Institute for Clinical Evaluative Sciences
Breast Neoplasms
Application of Intra-operative Prophylactic Antibiotics/Antiseptics in Chinese Breast Reconstruction Patients
The study aims to investigate different approaches of local application of antibiotics/antiseptics intraoperatively in Chinese patients undergoing post-mastectomy implant based breast reconstruction, and aims to single out an…
- Trial name
- NCT03742908
- Testing
- Cefazolin/clindamycin
- Where
- China
- Volunteers
- 291 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Obesity
Short- and Long-Term Effects of Antibiotics on Childhood Growth
The objectives of the proposed study are to assess the effects of different types, timing, and amount of antibiotic use in the first two years of life with (Specific Aim 1) body mass index (BMI) and obesity at ages 5 and 10 years…
- Trial name
- ABX (NCT02744846)
- Testing
- Antibiotics exposure
- Volunteers
- 681,739 people
- Sponsor
- Harvard Pilgrim Health Care