Clinical trials: Low-Birth-Weight
Infant, Very Low Birth Weight
Efficacy of Prophylactic Glycerin Suppositories for Feeding Intolerance in Very Low Birth Weight Preterm Infants: a Randomized Trial
To evaluate the efficacy of prophylactic glycerin suppositories will accelerate the elimination of meconium from the large intestine and thus reduce the incidence of feeding intolerance in very low birth weight (VLBW) infants
- Trial name
- NCT01799629
- Testing
- Glycerin suppositories
- Where
- 3 sites in Saudi Arabia
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- King Faisal Specialist Hospital & Research Center
Infant Development
Measurements of Anemia and Physiologic Tissue Response to Blood Transfusions in VLBW Infants Using Quantitative NIRS
The study quantified functional measures of red blood cell mass and oxygen in neonatal tissues using a non-invasive optical technique: near infrared optical spectroscopy .
- Trial name
- NCT00544375
- Testing
- Optical measurement
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of California, Irvine
Premature Birth, Perinatal Mortality
Assessing the Impact of Smoke-free Legislation on Perinatal Health in the Netherlands
The purpose of this study is to investigate whether there has been a change in perinatal outcomes following the phased smoking ban introduction (January 2004 for workplaces; July 2008 for bars and restaurants) workplaces in the…
- Conditions
- Premature Birth, Perinatal Mortality, Infant, Low Birth Weight, Stillbirth
- Trial name
- NCT02189265
- Testing
- Smoke-free legislation
- Where
- 2 sites in Netherlands, United Kingdom
- Volunteers
- 2,069,695 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Prematurity, Respiratory Distress Syndrome
Autologous Umbilical Cord Blood Transfusion for Preterm Neonates
This is a pilot study to test feasibility of collection, preparation and infusion of a baby's own (autologous) umbilical cord blood in the first 14 days after birth if the baby is born premature <35 weeks of gestation.
- Conditions
- Prematurity, Respiratory Distress Syndrome, Anemia of Prematurity, Intraventricular Hemorrhage
- Trial name
- NCT01121328
- Testing
- Autologous cord blood transfusion for preterm neonates, Autologous cord blood transfusion
- Where
- Egypt
- Sponsor
- Sahar M.A. Hassanein, MD
Infant; Premature, Light-For-Dates
Nephrocalcinosis in Very Low Birth Weight Infants
Extremely premature children benefit from specific follow-up that requires high nutritional intake and the use of specific therapies that expose them to the risk of nephrocalcinosis.
- Trial name
- NCT04860583
- Testing
- Renal ultrasound
- Volunteers
- 265 people
- Sponsor
- Hospices Civils de Lyon
Indirect Hyperbilirubinemia
Effect of Saccharomyces Boulardii on Indirect Hyperbilirubinemia and Phototherapy Duration in Very Low Birth Weight Infants
Indirect hyperbilirubinemia is frequently observed in premature infants.Probiotics are favorable microorganisms that regulate the flora of the gastrointestinal system. In this study we aimed to compare the effect of S.
- Trial name
- NCT01411761
- Testing
- Reflor, serum physiologic
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Intrauterine Growth Restriction
Prediction of Low Birth Weight Infants Using Ultrasound Measurement of Placental Diameter and Thickness
Prediction of Low Birth Weight Infants using Ultrasound Measurement of Placental Diameter and Thickness
- Trial name
- NCT01501851
- Where
- Egypt
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Meconium Obstruction of Prematurity
Intestinal Fatty Acid Binding Protein in Very Low Birth Weight Infants With Meconium Obstruction
Urinary intestinal fatty acid binding protein (i-FABP), a marker of intestinal mucosal cell damage, has recently been proposed as a clinically useful measure in the early detection of necrotizing enterocolitis (NEC).
- Trial name
- NCT02864446
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Hospital
Malaria, Pregnancy
A New Approach to Deliver Malaria Preventions to Pregnant Women at a Community Level in Uganda
SUMMARY Background: Malaria is the leading cause of morbidity and mortality among pregnant women in Uganda. Although effective tools for prevention and control of malaria exist, their delivery presents a problem.
- Conditions
- Malaria, Pregnancy, Anemia
- Trial name
- NCT00118027
- Testing
- sulphadoxine-pyrimethamine intermittent preventive treatment
- Where
- Uganda
- Volunteers
- 2,150 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Pulmonary Hypertension, Infant, Premature
Novel Echocardiographic Methods for Early Identification of Neonates at Risk for Chronic Pulmonary Hypertension
Chronic pulmonary hypertension (cPHT) is a serious cardiopulmonary disorder that causes low oxygen levels in the blood, difficulty in breathing and ultimately heart failure.
- Trial name
- NCT04402645
- Where
- 6 sites in United States, Canada and 2 more
- Volunteers
- 350 people
- Sponsor
- Mount Sinai Hospital, Canada
Prematurity; Extreme, Growth Retardation
Nutritional Care and Head Growth in Preterm Infants
As extremely low birth weight infants are high-risk patients, the study aimed to compare neonatal care, nutritional strategy and postnatal growth of these infants in two European neonatal units.
- Trial name
- KARLY (NCT03635944)
- Where
- France
- Volunteers
- 71 people
- Sponsor
- Hôpital de la Croix-Rousse
Extremely Low Birth Weight
The Effect of Schumann Resonance on Preterm Newborns
Body weight gain is crucial for preterm newborns, especially those with a low birth weight. Owing to their noninvasive, noncontact, and non-pharmaceutical properties, extremely low frequency electromagnetic fields (ELF-EMFs) are…
- Trial name
- NCT05146752
- Testing
- extremely low frequency electromagnetic fields, routine care
- Where
- Taiwan
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Low; Birthweight, Breast Feeding, Exclusive
Indonesia After Discharge LBW Infant HMF Supplementation Study
Low birth weight (LBW) infant (1800-2449 gram) will be given the new human milk fortifier (HMF) which contains protein, lipid, carbohydrate and micronutrients after discharge.
- Conditions
- Low; Birthweight, Breast Feeding, Exclusive, Gestational Age and Weight Conditions
- Trial name
- DAHLIA (NCT04954807)
- Testing
- human milk fortified
- Where
- 4 sites in Indonesia
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Hyperbilirubinemia, Neonatal, Jaundice, Neonatal
Trial of Aggressive Versus Conservative Phototherapy in Infants <1,000 Grams Birth Weight
This multi-center, randomized clinical trial compared different bilirubin levels as thresholds for timing of phototherapy in extremely low birth weight infants.
- Conditions
- Hyperbilirubinemia, Neonatal, Jaundice, Neonatal, Infant, Newborn, Infant, Low Birth Weight
- Trial name
- Phototherapy (NCT00114543)
- Testing
- Aggressive Phototherapy 501-750g, Aggressive Phototherapy 751-1000g, Conservative Phototherapy 501-750g
- Where
- 17 sites in United States
- Volunteers
- 1,974 people
- Sponsor
- NICHD Neonatal Research Network
Extubation Failure
Bubble Continuous Positive Airway Pressure (CPAP) With Conventional CPAP for Extubation in Preterm Infants
The objective of this study is to evaluate whether CPAP delivered by bubble CPAP resulted in a greater proportion of infants being successfully extubated when compared with management with ventilator derived CPAP.
- Trial name
- NCT00979433
- Testing
- Bubble CPAP, Conventional CPAP
- Where
- India
- Volunteers
- 32 people
- Sponsor
- All India Institute of Medical Sciences
Infant, Very Low Birth Weight, Calcium Deficiency
Identifying Vitamin D Deficiency in Very Low Birth Weight Infant (VLBW) Infants Part 2
This study is to determine the amount of vitamin D required for a very low birth weight infant to reach vitamin D sufficiency and achieve optimal calcium health and bone growth.
- Conditions
- Infant, Very Low Birth Weight, Calcium Deficiency, Vitamin D Deficiency
- Trial name
- NCT01363167
- Testing
- 400 IU Cholecalciferol- Vitamin D Daily
- Where
- 2 sites in United States
- Volunteers
- 68 people
- Sponsor
- Medical University of South Carolina
Infant, Newborn, Infant, Low Birth Weight
Physiologic Definition of Bronchopulmonary Dysplasia
This observational study was conducted to design and test a physiologic definition for bronchopulmonary dysplasia at 36 weeks of life.
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Trial name
- PhysiologicDef (NCT01223287)
- Where
- 21 sites in United States
- Volunteers
- 410 people
- Sponsor
- NICHD Neonatal Research Network
Low-Birth-Weight Infant, Breast Feeding
Finger Feeding as a Method of HMF Supplementation After Discharge
Human Milk Fortifier (HMF) is designed to supply additional calories, protein, vitamins and minerals to infants less than 37 weeks gestation or those less than 1500 g at birth.
- Trial name
- NCT04036240
- Testing
- Finger feeding
- Where
- 4 sites in Indonesia
- Volunteers
- 78 people
- Sponsor
- Fakultas Kedokteran Universitas Indonesia
Very Preterm Infant, Very Low Birthweight
LIFT-UP: Randomized Controlled Trial of Fortification of Human Milk
The goal of the LIFT-UP randomized controlled trial is to evaluate the efficacy of feeding routinely and fortified human milk using a standardized clinical protocol to very low birthweight (VLBW) or very preterm (VPT) infants in…
- Trial name
- LIFT-UP RCT (NCT06765863)
- Testing
- Human Milk Fortifier, Volume targets
- Where
- 4 sites in India
- Volunteers
- 776 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Low Birth Weight, Prematurity
The Impact of Extreme Environmental and Security Conditions on Prematurity and Low Birth Weight Rates
Numerous reports indicate that various extreme environmental and security-related situations during pregnancy may increase the risk of prematurity, LBW, and miscarriage, as these events increase both the incidence and intensity…
- Trial name
- NCT07531134
- Testing
- No intervention
- Where
- Israel
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center