Clinical trials: Lower Extremity Surgery
Surgical Procedures, Operative
The T REX Pilot Study: a Study to Investigate the Use of an Alternative Anaesthetic in Infants.
Animal studies suggest general anaesthetics harm the developing brain. It is unclear if these findings are relevant to humans but the issue has become a major concern.
- Trial name
- NCT02353182
- Testing
- Dexmedetomidine, Remifentanil, Bupivacaine
- Where
- 6 sites in United States, Australia and 1 more
- Volunteers
- 60 people
- Sponsor
- Murdoch Childrens Research Institute
Cerebral Palsy, Gait Analysis
Changes in Upper Limb Kinematics in Children With Cerebral Palsy After Lower Limb Surgery
İntroduction The upper limb can be involved in children with cerebral palsy (CP), while the lower limb is more commonly affected.
- Conditions
- Cerebral Palsy, Gait Analysis, Gait Disorders, Neurologic, Gait Disorders in Children
- Trial name
- NCT05957783
- Testing
- Cerebral palsy Gait analysis technique
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people
- Sponsor
- Istanbul University
Cerebral Palsy
Effectiveness of Education in Relaxation Surgeries
The study will be carried out with volunteer patients who are followed up by the Orthopedics and Traumatology outpatient clinic of Muğla Training and Research Hospital and diagnosed with Cerebral Palsy and meet the study…
- Trial name
- NCT06009354
- Testing
- Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Muğla Sıtkı Koçman University
Infants or Children Undergoing Open Heart Surgery
The Influence of Passive Leg Elevation on the Cross-sectional Area of the Internal Jugular Vein in Infants or Young Children Undergoing Open Heart Surgery
The trendelenburg position is usually applied to increase the cross-sectional area of the IJV. However, trendelenburg position requires a tilt table to place the head in the down position.
- Trial name
- NCT01401920
- Testing
- leg elevation, Trendelenburg position, Trendelenburg position + passive leg elevation
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Samsung Medical Center
Anterior Cruciate Ligament Injuries, Opioid Use
Safe Options for ACL Recovery
The purpose of the proposed work is to test a brief opioid exposure reduction program (ACL-OERP) designed to improve health literacy about opioid use following surgeries.
- Trial name
- SOAR (NCT04225468)
- Testing
- ACL Opioid Exposure Reduction Program
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Karen Derefinko, PhD
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Tendon-Bone Versus All-Soft-Tissue for ACL Reconstruction: A Patient-Blinded Randomized Clinical Trial
In primary pediatric Anterior cruciate ligament (ACL) reconstruction, the quadriceps tendon with either tendon and patellar bone or an all-tendon graft is commonly employed.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
- Trial name
- NCT04039971
- Testing
- ACL Reconstruction
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Colorado, Denver
Femur Distal Fracture, Nonunion of Fracture
Distal Femur Fracture Nonunion - Statistical Analysis Plan
Here the investigators describe the statistical analysis plan for the study assessing the prediction of fracture nonunion leading to secondary surgery in patients with distal femur fractures.
- Trial name
- NCT05163795
- Testing
- Lateral locking plate
- Where
- Finland
- Volunteers
- 299 people
- Sponsor
- Töölö Hospital
Anterior Cruciate Ligament Injury
Clinical Outcome Following Arthroscopic Knee Surgery
Purpose: There are no existing data available to guide clinicians in the appropriate rehabilitation progression of patients who have undergone knee arthroscopy.
- Trial name
- (COFAKS) (NCT03700996)
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- The University of Texas Health Science Center, Houston
Hip Fractures
Patient-Centered Education After Hip Fracture Surgery
This randomized controlled trial aims to evaluate the effect of a structured patient-centered educational program on postoperative outcomes among patients undergoing hip fracture surgery.
- Trial name
- PCE-HFS (NCT07739225)
- Testing
- Structured Patient-Centered Educational Program.
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Flat Foot Acquired Bilateral (Pes Planus)
Clinical and Radiological Evaluation Over 10 Years After Bilateral Subtalar Arthrorisis Surgery With Endorthesis and Calcaneal Stop for the Correction of Pediatric Flatfoot
VARIABLES TO BE COLLECTED AND SOURCE The primary efficacy endpoint will be the maintenance of flatfoot correction over time, assessed both clinically (tip-toe test, Jack test, tip-toe walking test) and radiologically (evaluation…
- Trial name
- ARTRO-LONG (NCT07569835)
- Testing
- calcaneo stop and endorthesis
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Istituto Ortopedico Rizzoli
Lower Limb Injury
IV Steroids Versus Steroids Included in Block for Orthopedic Lower Limb Surgery
IV and included steroids have produced the same length of block prolongation in adults as if the steroid was given with the nerve block. Clinically, this has not be noticed in children.
- Trial name
- NCT03855059
- Testing
- Dexamethasone Sodium Phosphate
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Arizona
Anterior Cruciate Ligament Rupture
Improving Maximal Strength in the Initial Postoperative Phase After Anterior Cruciate Ligament Reconstruction Surgery: Randomized Controlled Trial of an App-Based Serious Gaming Approac
The investigators designed a prospective randomized trial to evaluate whether an app based active muscle training program (GenuSport) can improve the postoperative strength by starting rehabilitation immediately after primary…
- Trial name
- NCT04224376
- Testing
- App based Serious Gaming with the Genu Sport knee trainer
- Volunteers
- 26 people
- Sponsor
- Hannover Medical School
Hip Dysplasia, Hip Injuries
PENG Block vs. ESP Block for Pediatric Hip Surgery
The study compares the effectiveness and safety of the pericapsular nerve blockade vs. ESPB in pediatric patients who underwent hip surgeries.
- Conditions
- Hip Dysplasia, Hip Injuries, Hip Fractures, Hip Disease
- Trial name
- NCT06087549
- Testing
- Pericapsular nerve group block using 0.2% ropivacaine, Erector Spinae Plane Block using 0.2% ropivacaine, Standard care
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
Pes Planovalgus
New Bone Grafting Technique in Paediatric Foot Surgery. Validation of Outcome Measures
The purpose of this study is to determine whether structural calcium ceramic bone graft substitute (ReproBone™) is non-inferior compared to autologous tricortical iliac crest bone graft in lateral calcaneal lengthening…
- Trial name
- NCT01770574
- Testing
- ReproBone, calcaneal lengthening
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- University of Aarhus
Osteotomy of Lower Extremity
PediLoc® Blade Plate in Distal Femoral Osteotomies
Background: The PediLoc® Locking Cannulated Blade Plate System, originally designed for proximal femoral osteotomies, has also been used for multidimensional deformity correction of the distal femur.
- Trial name
- NCT06950047
- Testing
- distal femoral osteotomies using the PediLoc® Locking Cannulated Blade Plate System, distal femoral osteotomies using the 90°LCP-PCP
- Where
- Switzerland
- Volunteers
- 111 people
- Sponsor
- University Children's Hospital, Zurich
Lower Extremity Fracture
Atropine Versus Glycopyrrolate in Preventing Spinal Anesthesia Induced Hypotension in Lower Limb Surgeries
A study to compare between intravenous atropine and glycopyrrolate in preventing spinal anesthesia induced hypotension in patients undergoing major lower limb orthopedic surgeries.
- Trial name
- NCT03580889
- Testing
- Atropine, Glycopyrrolate, Normal Saline Flush, 0.9% Injectable Solution
- Where
- Nepal
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
Soft Tissue Sarcoma
Prehabilitation Soft-Tissue Sarcoma of Lower Limb
This study is about preparing people with cancerous tumours, soft-tissue sarcoma (STS), in the leg to recover more quickly from surgery.
- Trial name
- NCT04518488
- Testing
- Exercises, Informational Support Group (Control group)
- Volunteers
- 30 people
- Sponsor
- McGill University
Proximal Femoral Fracture, Dinamic Hip Surgery
Motion Graphic Training for Scrub Nurses in Hip Surgery
This pilot randomized controlled trial evaluates the effect of motion graphic video-based training on the performance of scrub nurse students during dynamic hip screw (DHS) surgery.
- Trial name
- NCT07701564
- Testing
- Motion Graphic Video Training, Routine Clinical Training
- Where
- Iran
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Arak University of Medical Sciences
Hypotension, Hip Fractures
Heart and Renal Failure in Hip Fracture Surgery
Patients with acute hip fractures are old and vulnerable. With a majoriry classified as being ASA 3 or more. Frequently they receive spinal anesthesia perioperatively inducing hypotension.
- Conditions
- Hypotension, Hip Fractures, Renal Insufficiency, Heart Injuries
- Trial name
- NCT03532919
- Testing
- Serum Tropinin
- Where
- Sweden
- Volunteers
- 105 people
- Sponsor
- Sahlgrenska University Hospital
Fracture Arm, Fracture Closed of Lower End of Forearm, Unspecified
A Clinical Trial on the Use of Lidocaine Infusion During Surgery for Pediatric Upper Extremity Fractures and Its Impact on Total Perioperative Opioid Requirements
This study is a prospective, randomized, double-blind clinical trial evaluating whether intraoperative intravenous lidocaine infusion (IVLI) reduces opioid requirements and improves postoperative pain control in children…
- Conditions
- Fracture Arm, Fracture Closed of Lower End of Forearm, Unspecified, Fracture Elbow, Fracture Fixation
- Trial name
- NCT07552766
- Testing
- Lidocaine Infusion, Standard of Care (SOC)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Nemours Children's Clinic