Clinical trials: Luminal Breast Cancer
Breast Cancer, Breast Cancer (Early Breast Cancer)
Luminal Breast Cancer Cryoablation
LUBRECA will evaluate the safety and efficacy of cryoablation with liquid nitrogen to treat cT1cN0 luminal breast cancer diagnosed in postmenopausal women
- Trial name
- LUBRECA (NCT07447414)
- Testing
- Cryoablation with liquid nitrogen (Prosense® system)
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Lucía Graña López
Immune Microenvironment, Luminal A
Tumor Immune Mechanism of Axillary Lymph Node Metastasis in Early Luminal Type A Breast Cancer
Luminal type A breast cancer is a type with good clinical prognosis, and the proportion of lymph node metastasis is low, but a small number of patients have more lymph node metastasis when the primary tumor is very small, and the…
- Conditions
- Immune Microenvironment, Luminal A, Lymph Node Metastases
- Trial name
- NCT04322331
- Testing
- no intervention
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University People's Hospital
Breast Cancer, Lymph Node Metastases
Role of SIRT1 in Regulation of Epithelial-to-mesenchymal Transition in Breast Cancer Lymph Nodes Metastasis
Luminal A breast cancer is a kind of breast cancer with low rate lymph node metastasis and good survival. But in clinical practice, Luminal A breast cancer can present with early, unexpected lymph node metastasis some time…
- Trial name
- NCT04137406
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Peking University People's Hospital
Metastatic Breast Cancer, ER Positive Breast Cancer
To Identify Primary Resistance to CDK4/6 Inhibitors in Breast Cancer
This is a multi-center biomarkers study aiming to prospectively collect biological samples from patients with ER+ and HER2-negative metastatic breast cancer, who are candidate to first-line treatment with an aromatase inhibitor…
- Conditions
- Metastatic Breast Cancer, ER Positive Breast Cancer, HER2-negative Breast Cancer
- Trial name
- TIRESIAS (NCT04660435)
- Testing
- Thymidine kinase activity
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Fondazione Sandro Pitigliani
HR Positive/HER-2 Negative Breast Cancer
MRI-Driven Precision Typing and Response Prediction in Luminal Breast Cancer
Luminal breast cancer is characterized by marked heterogeneity, resulting in diverse treatment responses and long-term outcomes.
- Trial name
- NCT07692230
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Fudan University