Clinical trials: Lung Function Tests
Cerebral Palsy, Respiratory Function Tests
Respiratory Function, Respiratory Muscle Strength, and Hand Function in Hemiparetic Cerebral Palsy
The goal of this observational study is to learn how respiratory function and respiratory muscle strength are related to hand use in children and teenagers with hemiparetic cerebral palsy (CP) aged 6 to 18 years.
- Conditions
- Cerebral Palsy, Respiratory Function Tests, Fine Motor Skills
- Trial name
- NCT07394439
- Volunteers
- 37 people
- Sponsor
- Halic University
Pulmonary Disease
Evaluation of the Causes and Disease Processes of Chronic Lung Disease
Chronic lung diseases are disorders associated with abnormalities in any of the structures involved in the process of breathing and bringing oxygen into the lungs and blood.
- Trial name
- NCT00001183
- Where
- United States
- Volunteers
- 6,564 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cystic Fibrosis (CF), Cystic Fibrosis in Children
Physical Impairments in Children With Cystic Fibrosis
It is aimed to reveal impairments regarding urinary incontinence, dyspnea, muscle strength, functional capacity or quality of life in children and adolescents with cystic fibrosis compared to healthy children and adolescents.
- Trial name
- NCT06984679
- Testing
- Physical Evaluations in Children with Cystic Fibrosis, Physical Evaluations in Healthy Children
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Izmir Democracy University
Respiratory Distress Syndrome of Prematurity (Surfactant Dysfunction), Bronchopulmonary Dysplasia
Trial of Late Surfactant to Prevent BPD: A Pilot Study in Ventilated Preterm Neonates Receiving Inhaled Nitric Oxide
The purpose of this study is to determine if the combination of late doses of Infasurf with inhaled nitric oxide will interact to improve the surfactant function and thus the respiratory status and outcome of treated infants.
- Trial name
- TOLSURFPilot (NCT00569530)
- Testing
- Infasurf (ONY Inc.)
- Where
- 9 sites in United States
- Volunteers
- 85 people
- Sponsor
- Roberta Ballard
Esophageal Cancer, Lung Cancer
4-Dimensional CT Derived Ventilation Versus SPECT Aerosol Ventilation in Patients With Thoracic Malignancies
Objectives: Primary Objective: 1. To determine the correlation between 4-dimensional computed tomography (4D CT) derived ventilation and single photon emission tomography (SPECT) aerosol Tc-99m determined ventilation.
- Trial name
- NCT00531180
- Testing
- 4D CT scans, Lung Function Imaging
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- M.D. Anderson Cancer Center
Asthma
Mechanism(s) of Airflow Limitation During Exacerbation of Asthma
The purpose of this study is to evaluate the site and mechanisms responsible for expiratory airflow limitation in chronic, treated, non-smoking, stable asthmatics with moderate to severe persistent expiratory airflow obstruction.
- Trial name
- NCT01225913
- Testing
- fluticasone/salmeterol in all asthmatics, budesonide/formoterol or fluticasone/salmeterol in all asthmatics
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Gelb, Arthur F., M.D.
Cystic Fibrosis
Dissection of Staphylococcus Aureus Infection From Colonization in Cystic Fibrosis Patients
Staphylococcus aureus is not only one of the first pathogens infecting the airways of cystic fibrosis (CF) patients, but also a highly prevalent microorganism (>60% of all CF patients; European and American CF registries; (4,25)…
- Trial name
- StaphCI (NCT00669760)
- Testing
- non-interventional study
- Where
- 17 sites in Austria, Germany
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster
Cystic Fibrosis
Effects of an Individualized Exercise Program on Health-related and Skill/Performance-related fitness in CF.
The aim of this study is to evaluate the effects of a partially supervised exercise program on different aspects of physical fitness, despite VO2peak, lung function, quality of life and sleep quality in children, adolescents and…
- Trial name
- NCT03518697
- Testing
- exercise program
- Where
- 3 sites in Germany
- Volunteers
- 100 people
- Sponsor
- University Hospital, Essen
Blood Pressure, Lung Function
Sustainable Household Energy Adoption in Rwanda (SHEAR)
Investigators will conduct a randomized controlled trial substituting traditional forms of household energy (biomass for cooking and kerosene for lighting) with liquified petroleum gas (LPG) stoves/fuel and solar power (in areas…
- Trial name
- SHEAR (NCT05668624)
- Testing
- Clean household energy
- Where
- Rwanda
- Volunteers
- 1,680 people
- Sponsor
- Colorado State University
Hypoxemia of Newborn
Lung Function Monitoring During Hypoxemia Episodes
Premature infants commonly have desaturation episodes due to different reasons such as cessation of breathing or loss of lung volume.
- Trial name
- NCT06535074
- Testing
- Detecting changes in lung volume with hypoxemia episodes
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Rutgers, The State University of New Jersey
Asthma, Wheezing
Lung Function and Structure in Healthy Infants and Infants With Recurrent Wheezing
Infants will be enrolled into this study in one of three groups. First, there will be a group of full term infants with no history of wheezing.
- Conditions
- Asthma, Wheezing, Infant
- Trial name
- NCT00507676
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Indiana University
Cystic Fibrosis
Retrospective Observational Study to Compare Cystic Fibrosis Patients in Two Decades Before and After 2000
The purpose of this study is to describe two cohorts of cystic fibrosis patients treated in 2 different decades in terms of FEV1 (Forced Expiratory Volume in one second) maintenance.
- Trial name
- MAESTRALE (NCT01651455)
- Where
- Italy
- Volunteers
- 92 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Asthma
The Correlations of FeNO, Blood Eosinophils and Lung Function in Well-controlled Asthma
In Asthma, the levels of exhaled FeNO is correlated to sputum eosinophils particularly in the patient with poor controlled asthma or severe asthma.
- Trial name
- NCT04454385
- Testing
- Patients with well controlled asthma
- Where
- Thailand
- Volunteers
- 84 people
- Sponsor
- Hat Yai Medical Education Center
Respiratory Distress Syndrome, Adult, Bronchiolitis Obliterans
Etanercept for Non-Infectious Lung Injury Following Bone Marrow Transplantation
The purpose of this study is to determine the effects of etanercept, and define the toxicity, when administered to patients with acute non-infectious lung injury (idiopathic pneumonia syndrome, IPS) and with subacute pulmonary…
- Conditions
- Respiratory Distress Syndrome, Adult, Bronchiolitis Obliterans, Pneumonia
- Trial name
- NCT00029328
- Testing
- etanercept
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- FDA Office of Orphan Products Development
Asthma
Effects of Noninvasive Ventilation Compared to Salbutamol
Asthma is a chronic inflammatory disease characterized by recurrent and reversible episodes of airway obstruction. Drug treatment usually includes inhaled corticosteroids and bronchial dilators, which often do not have adequate…
- Trial name
- NCT03430505
- Testing
- Bilevel, Albuterol
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Nove de Julho
Lung Diseases
Assessment of Exposures of the Mother-infant Pair to the Air Pollution of São Paulo
A single group of pregnant women who was analyzed in the first and in the third trimesters of pregnancy
- Trial name
- NCT02807038
- Testing
- Lung function test
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Mild Asthma
PAXT: Pulmonary Imaging of Mild Asthma Using 129Xe MRI and Tc-99-Labeled-Carbon-Imaging (Tc99CImaging)
The goal of this observational study is to better understand how asthma affects the lungs in young adults (ages 17-35) with mild asthma.
- Trial name
- PAXT (NCT07143747)
- Testing
- Hyperpolarized 129Xe MRI, Tc-99m Technegas Ventilation Imaging
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Dr. Grace Parraga
Pneumonia, Pollution; Exposure
The Effect of Household Air Pollution on Lung Function Growth in Infants With Pneumonia in Sub-Saharan Africa
This study will evaluate the feasibility and acceptability of a household-based clean air intervention
- Conditions
- Pneumonia, Pollution; Exposure, Lung Function Decreased, Chronic Respiratory Disease
- Trial name
- PLUS2 (NCT05724082)
- Testing
- Clean Air Intervention
- Where
- Uganda
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Kartagener Syndrome
Long-term Lung Function and Disease Progression in Children With Early Onset Primary Ciliary Dyskinesia Lung Disease
Primary ciliary dyskinesia (PCD), also known as Kartagener syndrome, is a genetic disorder of the cilia, which are microscopic hair-like cells.
- Trial name
- NCT00722878
- Where
- 6 sites in United States, Canada
- Volunteers
- 48 people
- Sponsor
- University of North Carolina, Chapel Hill
Cystic Fibrosis
Effects of Inspiratory Muscle Training on Postural Stability, Balance, Pulmonary Function and Functional Capacity in Children With Cystic Fibrosis
It is extensively reported in the literature that patients with chronic obstructive lung disease may have impairments in balance and postural control which further increase the disease burden.
- Trial name
- NCT03375684
- Testing
- Conventional chest physiotherapy, Inspiratory muscle training
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Bezmialem Vakif University