Clinical trials: Lung Resection
Lung Cancer, Quality of Life
Quality of Life and Pain Outcomes Following Video-Assisted Thoracic Surgery (VATS) Anatomic Lung Resection Versus Thoracotomy and Anatomic Lung Resection
The purpose of this study is to see if different types of surgery for lung cancer have different effects on quality of life and pain.
- Conditions
- Lung Cancer, Quality of Life, Video-assisted Thoracic Surgery (VATS), Thoracotomy
- Trial name
- NCT00598000
- Testing
- questionnaires
- Where
- United States
- Volunteers
- 216 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Pulmonary Malformation
Can Pre-operative Flexible 3D Models of Pulmonary Malformations Facilitate Thoracoscopic Resection
The National Rare Diseases plans, the ongoing MALFPULM PHRC and thoracoscopic advents in children, are remarkable improvements in understanding and managing lung malformations.
- Trial name
- 3DLP (NCT03913416)
- Testing
- 3D printed model, Control group
- Where
- France
- Volunteers
- 178 people
- Sponsor
- Hospices Civils de Lyon
Thoracic Surgery, Video-Assisted
Preoperative Stereoscopic Localization Versus Methylene Blue Localization in GGO Wedge Resection
This study evaluates the feasibility，accuracy and safety of Preoperative Stereoscopic Localization Versus Methylene Blue Localization in GGO Wedge Resection.
- Trial name
- PSLVML (NCT03252210)
- Testing
- Preoperative Stereoscopic Localization
- Volunteers
- 20 people
- Sponsor
- Guangdong Provincial People's Hospital
Congenital Lung Malformation
Early Outcomes of Thoracoscopic Anatomical Lesion Resection for Congenital Lung Malformations in Children: A Single-Center Experience in a Limited-Resource Country
This study aimed to evaluate the safety and efficacy of thoracoscopic resection for CLMs in pediatric patients.
- Trial name
- NCT07859774
- Volunteers
- 30 people
- Sponsor
- Al-Azhar University
Non-small Cell Lung Cancer
The Recurrence Gene Profiles of Adjuvant Osimertinib Therapy in Resected Non-Small-Cell Lung Cancer
This study was a multicenter, real-world observational study aimed at characterizing the genomic landscape of recurrence in patients with EGFR-sensitizing mutation-positive early-stage (clinical stage IB-IIIA) non-small cell lung…
- Trial name
- RAISE (NCT06477055)
- Where
- 2 sites in China
- Volunteers
- 43 people
- Sponsor
- Hunan Province Tumor Hospital
Pediatric Cancer, Neuroblastoma
Biomarkers of Resiliency In Childhood Cancer Surgery
This observational study is to better understand how children and their families recover after the stress of major surgery for cancer so that investigators can create ways to improve resilience during recovery.
- Conditions
- Pediatric Cancer, Neuroblastoma, Sarcoma, Wilms Tumor and Other Childhood Kidney Tumors
- Trial name
- BRICCS (NCT06674811)
- Testing
- Wearing Smartwatch, Patient Report Outcomes, Blood Draw
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Pulmonary Neoplasm
Trial of Pre-operative Chemoradiotherapy Followed by Surgical Resection in Pancoast Tumors (JCOG 9806)
The purpose of this study is to evaluate the safety and efficacy of the trimodality (concurrent chemoradiotherapy followed by surgical resection) approach in superior sulcus tumors.
- Trial name
- NCT00128037
- Testing
- mitomycin C, vindesine, cisplatin and radiotherapy
- Where
- Japan
- Volunteers
- 75 people
- Sponsor
- Japan Clinical Oncology Group
Neoadjuvant Chemoimmunotherapy, Robotic Pulmonary Resection
Downstaging and RATS After Neo-Chemo-IO: Impact on Surgical Outcomes in NSCLC
The goal of this observational study is to learn whether tumor and nodal downstaging after neoadjuvant chemo-immunotherapy is associated with better surgical outcomes in patients with clinical stage IIB-III non-small cell lung…
- Conditions
- Neoadjuvant Chemoimmunotherapy, Robotic Pulmonary Resection, Stage IIB-III NSCLC
- Trial name
- DRAGON-NSCLC (NCT07528066)
- Testing
- Robotic-assisted surgery (RATS)
- Where
- 10 sites in China, France and 1 more
- Volunteers
- 200 people
- Sponsor
- Shanghai Chest Hospital
Lung Cancer, Ventricular Failure, Right
Right Side of Heart Function After Lung Surgery
The purpose of this study is explore the impact of lung cancer surgery on the function of the right side of the heart.
- Trial name
- NCT01892800
- Testing
- Lung resection
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- University of Glasgow
Lung Cancer, Ventricular Failure
Right Ventricular Inflammation After Lung Resection
The purpose of this study is explore the impact of lung cancer surgery on inflammation and function of the right side of the heart.
- Trial name
- NCT03523611
- Testing
- Lung Resection
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- University of Glasgow
Lung Neoplasms, Lymph Node Excision
Mediastinal Lymph Node Dissection Versus Spared Mediastinal Lymph Node Dissection in Stage I GGN NSCLC
Lung cancer is the leading cause of cancer related death worldwide. Lobectomy or sub-lobectomy with mediastinal lymph node dissection is the standard surgery. About 50% lung nodules are pure ground-glass or part-solid nodules.
- Trial name
- NCT04631770
- Testing
- Systemic mediastinal lymph node dissection, Spared mediastinal lymph node dissection
- Where
- China
- Volunteers
- 1,362 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Pulmonary Aspergillosis, Surgery-Complications
Uniportal VATS Resection for Pulmonary Aspergilloma : Evaluation of Prognostic Factors in a Single Center Experience
The objective of this study was to report our experience with U-VATS resection and to evaluate our surgical outcomes with an analysis of postoperative complications.
- Conditions
- Pulmonary Aspergillosis, Surgery-Complications, Thoracic Diseases
- Trial name
- NCT06564727
- Testing
- Uniportal VATS approach, VATS approach
- Where
- Morocco
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Hassan II University
Pulmonary Resection, Oxygen Therapy
Comparing The Outcome Of High Flow Oxygen Versus Conventional Oxygen In Extubated Patients After Lung Resection.
Conventional oxygen therapy (COT) is the main supportive treatment administered to patients postoperative after planned extubation and has conventionally been delivered using nasal prongs, cannula or masks.
- Trial name
- NCT05511636
- Testing
- Oxygen therapy
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Bone Sarcoma, Soft Tissue Sarcoma
In Vivo Lung Perfusion for Pulmonary Metastases of Sarcoma
Sarcoma which has spread to the lungs is most often treated with surgery. Even with surgery, most patients will not be cured and will die from their disease, probably because of small cancer cells that are present in the lungs at…
- Conditions
- Bone Sarcoma, Soft Tissue Sarcoma, Pulmonary Metastases
- Trial name
- NCT02811523
- Testing
- Doxorubicin
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- University Health Network, Toronto
Asthma
The Clinical Effect of MK0476 With Concomitant Administration of and Removal of Inhaled Beclomethasone in Asthmatic Patients (0476-029)
This study will investigate the additive effect of montelukast (MK0476) taken along with inhaled beclomethasone versus inhaled beclomethasone alone.
- Trial name
- NCT00911547
- Testing
- montelukast sodium, beclomethasone
- Volunteers
- 642 people
- Sponsor
- Organon and Co
Colon Cancer
Colon Cancer Prognosis After Radical Surgery
1. Radical surgery. It is supposed to improve prognosis of colon cancer. A surrogate measure of achievement of radical surgery is the number of lymph nodes removed with the specimen. 2. Markers.
- Trial name
- NCT00963352
- Where
- 2 sites in Norway
- Volunteers
- 300 people
- Sponsor
- Haraldsplass Deaconess Hospital
Indications for Laparoscopic Thoracic and Abdominal Surgery in Children, Congenital or Acquired Surgical Conditions Requiring Minimally Invasive Surgery in Children
Clinical Trial on Safety and Efficacy of Thoracoabdominal Endoscopic Surgical System for Pediatric Surgery
This is a prospective, multi-center, single-arm, target-value clinical trial conducted to evaluate the safety and effectiveness of the Thoracic and Abdominal Endoscopic Surgery System (model WJ-SR01-200) in pediatric surgical…
- Conditions
- Indications for Laparoscopic Thoracic and Abdominal Surgery in Children, Congenital or Acquired Surgical Conditions Requiring Minimally Invasive Surgery in Children, Pyeloplasty, Ureteral Reimplantation
- Trial name
- NCT07530133
- Testing
- Thoracic and Abdominal Endoscopic Surgery System
- Where
- 3 sites in China
- Volunteers
- 64 people
- Sponsor
- Hangzhou Kangji Weijing Medical Robotics Co., Ltd.
Lung Nodule
Single-lumen Endotracheal Intubation in ENB-guided Localization and Resection of Pulmonary Nodules
The goal of this clinical study is to evaluate the practicality, safety, and feasibility of a 'one-stop' single-lumen (SL) endotracheal intubation strategy for patients undergoing wedge resection of early-stage lung nodules with…
- Trial name
- NCT07288255
- Testing
- Single lumen, single-lumen to double-lumen
- Where
- China
- Volunteers
- 375 people
- Sponsor
- Ruijin Hospital
Neoplastic Disease, Solid Tumor
Indocyanine Green (ICG) Guided Tumor Resection
This is a study to assess the ability of Indocyanine Green (ICG) to identify neoplastic disease. For many pediatric solid tumors, complete resection of the primary site and/or metastatic deposits is critical for achieving a cure.
- Trial name
- NCT04084067
- Testing
- Indocyanine Green
- Where
- United States
- Volunteers
- 215 people
- Sponsor
- St. Jude Children's Research Hospital
Non-Small Cell Lung Cancer
Factors Determine the Feasibility and Surgical Margin Quality of Sublobar Resection for Non-small Cell Lung Cancer?
Sublobar resection (SR) has been recognized as non-inferior to lobectomy for small-sized non-small cell lung cancer (NSCLC). This study aimed to systematically identify the potential factors influencing the feasibility and…
- Trial name
- NCT07005401
- Where
- China
- Volunteers
- 1,064 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University