Clinical trials: Macronutrients
Prader Willi Syndrome, Syndromic Obesity
Prader-Willi Syndrome Macronutrient Study
The overall objective is to explore the mechanisms by which macronutrients regulate food intake and weight gain in Prader Willi Syndrome (PWS).
- Conditions
- Prader Willi Syndrome, Syndromic Obesity, Childhood Obesity
- Trial name
- NCT02011360
- Testing
- Low Carbohydrate diet, Low Fat diet
- Where
- 2 sites in United States, Canada
- Volunteers
- 10 people
- Sponsor
- Duke University
Obesity, Diabetes Mellitus, Type 2
Study of the Potential of a Macronutrient Balanced Normocaloric Diet to Treat Lifestyle Diseases
One of today's major health problem in the western world is related to lifestyle. Lifestyle diseases include obesity, type 2 diabetes, cardiovascular diseases and different types of cancers.
- Conditions
- Obesity, Diabetes Mellitus, Type 2, Cardiovascular Diseases
- Trial name
- NCT01278121
- Testing
- Diet A, Diet B
- Where
- Norway
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Healthy, Deficiency Disease
Effects of Dietary Carbohydrate and Fat on Hormones
This study will try to determine if intake of dietary fats or carbohydrates influences the tendency to gain weight or accumulate body fat.
- Trial name
- NCT00016848
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Insufficient Breast Milk Syndrome, Premature Birth
Domperidone on the Composition of Preterm Breastmilk Using a Human Milk Mid-infrared Spectroscopy Analyzer
Maintaining milk production in lactating mothers who have delivered prematurely can be a challenge. In these cases, domperidone has been the most commonly used pharmacologic galactagogue.
- Trial name
- DompMilk (NCT06830226)
- Testing
- Test group, Reference group
- Where
- Portugal
- Volunteers
- 81 people
- Sponsor
- Centro Hospitalar de Lisboa Central
Obesity, Prader Willi Syndrome
Macronutrient Regulation of Ghrelin and Peptide YY
The hyperghrelinemia of children with PWS provides a unique model by which to explore the hormonal and metabolic effects of orexigenic hormones in normal and pathologic conditions.
- Trial name
- NCT02464514
- Testing
- High carbohydrate meal, High fat meal
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Duke University
Overweight, Eating Behavior
Eating Behavior in Adolescents
This study will explore the eating habits of adolescents and determine if eating behavior is linked to genetics. Healthy adolescents between 13 and 17 years of age may be eligible for this study.
- Conditions
- Overweight, Eating Behavior, Binge Eating
- Trial name
- NCT00631644
- Where
- United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Cystic Fibrosis
Development Of An Innovative Panel of Methods To Measure Intestinal Macronutrient Digestion, Absorption, and Function
Malnutrition is a significant problem in children and adults with Cystic fibrosis (CF). An impaired intestinal digestion and absorption capacity is one of the main factors responsible for the malnutrition in CF.
- Trial name
- NCT01494909
- Testing
- Ensure plus
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Obesity
Developmental Adaptation to an Obesogenic Environment
The purpose of this study was to evaluate whether birth weight is related to the demand for dietary protein in adult survivors of severe acute malnutrition (Kwashiorkor and Marasmus), and that leveraging of protein intake is…
- Trial name
- NCT02257593
- Testing
- Dietary protein
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
Type1diabetes
Evaluation of the Glucose Metrics After Eating Pizza Margherita in Hybrid Closed Loop Users
In previous study the investigators proved that blood glucose after eating pizza margherita could be managed with a simple wave bolus of insulin in pediatric patients with type 1 diabetes under controlled conditions.
- Trial name
- NCT05729776
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- University of Campania Luigi Vanvitelli
Diabetes Mellitus, Type 1
Evaluation of a Mobile Application to Optimize Self-decision on Metabolic Control in Persons With Type 1 Diabetes
Adolescents with type 1 diabetes mellitus (T1 DM) tend to have poor metabolic control. There are no mobile applications in our language in our environment, and patients are accessible in addition to the difficulties involved in…
- Trial name
- DM-BLUE (NCT05143411)
- Testing
- PRE-test
- Where
- Dominican Republic
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad Iberoamericana
Diet Habit, Dietary Habits
Polish Infants and Toddler Nutritional Study
A cross-sectional study representative of the Polish population of children aged 5 months to 6 years conducted in the cross-sectional study model, the main objective of which is to assess the nutritional value of the diet of…
- Conditions
- Diet Habit, Dietary Habits, Diet, Healthy, Children
- Trial name
- PITNUTS (NCT06417151)
- Where
- Poland
- Volunteers
- 1,000 people
- Sponsor
- Fundacja Nutricia
Pediatric Obesity
PrOtein and WEight Loss in teenageRs
The aim of the proposed study is to provide important data on weight loss efficacy in overweight and obese adolescents on an isocaloric higher protein diet vs a lower protein diet utilizing the U.S.
- Trial name
- POWER (NCT02079831)
- Testing
- Energy Restriction, Higher protein, Lower Protein
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Type 1 Diabetes (T1D)
Effects of Bedtime Snack Composition on Overnight Glucose in Children and Adolescents With Type 1 Diabetes
This study compared four types of bedtime snacks in children and adolescents with type 1 diabetes treated with multiple daily insulin injections.
- Trial name
- NCT07778147
- Testing
- Carbohydrate-Only Bedtime Snack, Carbohydrate-Plus-Protein Bedtime Snack, Carbohydrate-Plus-Fat Bedtime Snack
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Didem Güneş Kaya
Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis
A Double-blind, Randomized, Multicenter, Cross-over Study to Compare the Effect of Creon N and Creon® on Fat Digestion in Subjects ≥ 12 Years of Age With Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis
maldigestion of dietary macronutrients (pancreas not producing enough enzymes for digestion of fat, sugars and proteins) in Cystic Fibrosis
- Trial name
- NCT02137382
- Testing
- Creon®, Creon N
- Where
- 7 sites in Hungary, Spain
- Volunteers
- 41 people
- Sponsor
- Abbott
Eating Behaviors
Eating Behavior in Children
This study will explore the eating habits of children and determine if eating behavior is linked to genetics. Children between 8 and 17 years of age may be eligible for this study.
- Trial name
- NCT00320177
- Where
- United States
- Volunteers
- 263 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Diabetes
Food Intake and Appetite in the Children of Mothers With Diabetes
This protocol is for study of the effect of inhibition of parasympathetic outflow on insulin secretion and glucose metabolism. Insulin secretion will be measured during infusions of escalating doses of atropine.
- Trial name
- NCT00339313
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Postnatal Growth Disorder
Target Fortification of Breast Milk: How Often Breast Milk Needs to be Measured?
It has been observed that target fortification on different schedules leads to meal to meal variation. It changes the ratio of protein to energy and the percentage of carbohydrate to non-protein energy which may, affect growth.
- Trial name
- TFO2 (NCT02865941)
- Testing
- Fortification with modular protein, Fortification with modular carbohydrate, Fortification with modular fat
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- McMaster Children's Hospital
Growth, Body Composition
How Infant Diets Would Affect Growth in Early Childhood
The investigators research group conducted a feeding study in 2012 (IRB 07-0003) that included breastfed infants consuming different infant solid foods.
- Conditions
- Growth, Body Composition, Gut Health
- Trial name
- FYI-FU (NCT02440503)
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Healthy
A Study of the Impact of Different Delivery Modes on Specific Macronutrient Components in Human Milk
The aim of the study is to evaluate the impact of different delivery modes on specific macronutrient components in human milk.
- Trial name
- ZoomMING (NCT05516940)
- Where
- China
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Infant Development, Protein-energy; Imbalance
Protein Turnover in Preterm Infants - Feeding of Target Fortified Breast Milk With Different Macronutrient Composition to Improve Growth
The purpose of this study is to measure protein turnover rates in preterm infants.
- Conditions
- Infant Development, Protein-energy; Imbalance, Protein Deposition
- Trial name
- NCT04854226
- Testing
- Macronutrients_CARB, Macronutrient_FAT
- Where
- 3 sites in Germany
- Volunteers
- 40 people
- Sponsor
- Paracelsus Medical University