Clinical trials: Magnesium Sulfate
Severe Pre-eclampsia With Postnatal Complication
Magnesium Sulfate in Pregnancy and Postpartum
There are huge doubts as to how long to keep postpartum magnesium sulfate. Studies demonstrating the usefulness for 24, 12 or 6 hours are of little evidence and do not take into account the use of magnesium sulphate before…
- Trial name
- MAG-PP (NCT02317146)
- Testing
- Magnesium Sulfate
- Where
- 3 sites in Panama
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Complejo Hospitalario Dr. Arnulfo Arias Madrid
Analgesia
Dexmedetomidine Versus Magnesium Sulphate Added to Bupivacaine in Infraorbital Nerve Block for Perioperative Analgesia in Paediatric Patients for Cleft Lip Surgery
Regional analgesia is considered the cornerstone for postoperative analgesia in paediatric patients. One of the most common birth defects which require surgical intervention early in life is the cleft lip.
- Trial name
- NCT05624151
- Testing
- Dexmedetomidine +Bupivacaine, Magnesium Sulfate + Bupivacaine, Bupivacaine
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Ain Shams University
Pre-eclampsia
Randomized Study of Nimodipine Versus Magnesium Sulfate in the Prevention of Eclamptic Seizures in Patients With Severe Preeclampsia
OBJECTIVES: I. Determine the effectiveness of nimodipine versus magnesium sulfate in the prevention of eclamptic seizures in patients with severe preeclampsia.
- Trial name
- NCT00004399
- Testing
- magnesium sulfate, nimodipine
- Volunteers
- 2,000 people
- Sponsor
- FDA Office of Orphan Products Development
Status Asthmaticus
Different Doses of Nebulized Magnesium Sulphate in Status Asthmaticus
In this study investigators will use magnesium sulphate in the nebulized form in children between 2 and 12 years of age as an acute reliever for acute severe asthma.
- Trial name
- NCT04929626
- Testing
- Magnesium Sulfate 500 mg/ml+ ventolin, Ventolin
- Where
- Pakistan
- Volunteers
- 126 people
- Sponsor
- Ziauddin University
Intraperitoneal Magnesium Sulphate in Laparoscope in Pediatrics
Intraperitoneal Magnesium Sulphate and Bupivacaine Versus Intravenous Analgesia in Laparoscopic Surgeries in Pediatrics
The investigators are going to study the analgesic efficacy of intraperitoneal instillation of a combination of Magnesium sulphate with bupivacaine versus ordinary used parenteral analgesics for pain relief after laparoscopic…
- Trial name
- NCT04651556
- Testing
- Magnesium Sulfate & bupivacaine, paracetamol & ketorolac
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Anesthesia Emergence Delirium
Dexmedetomidine Versus Ketamine Versus Magnesium Sulfate for the Prevention of Emergence Agitation Following Sevoflurane Induced Anesthesia in Cardiac Catheterization in Pediatrics
Emergence agitation (EA) is a post-operative behavioral disturbance was first reported in early 1960s. EA is a term used to describe non purposeful restlessness and agitation, thrashing, crying or moaning, disorientation and…
- Trial name
- NCT06077539
- Testing
- Dexmedetomidine, Ketamine, Magnesium
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Agitation,Psychomotor
The Effect of Intraoperative Magnesium Sulfate Infusion on the Occurrence of Emergence Agitation
This study designed to evaluate the correlation between the effect of intraoperative magnesium sulfate infusion and the incidence of emergence agitation after pediatric ophthalmic surgery
- Trial name
- NCT03208452
- Testing
- Magnesium Sulfate, Normal saline
- Where
- South Korea
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Pediatric Burns
Magnesium Sulfate in Pediatric Burn Dressing Changes
Prospective feasibility trial utilizing adjuvant magnesium sulfate for analgesia/sedation during pediatric sedated burn dressing changes, which is ultimately hypothesized to decrease ketamine and/or sedative requirements.
- Trial name
- NCT07126795
- Testing
- magnesium sulfate, Normal Saline (0.9% NaCl)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Hennepin Healthcare Research Institute
Asthma in Children
Magnesium Sulfate in Bronchial Asthma and Acute Bronchiolitis in Children
Asthma is a prevalent disease that affects as many as334 million individuals worldwide, and is a major source of disability and premature death in children(1). Asthma affects 7.1 million children in the United States (2).
- Trial name
- NCT06955559
- Testing
- Magnesium sulfate
- Volunteers
- 60 people
- Sponsor
- Assiut University
Cerebral Palsy, Intraventricular Hemorrhage
Beneficial Effects of Antenatal Magnesium Sulfate (BEAM Trial)
As many more premature infants survive, the numbers of these infants with health problems increases. The rate of cerebral palsy (CP) in extremely premature infants is approximately 20%.
- Conditions
- Cerebral Palsy, Intraventricular Hemorrhage, Periventricular Leukomalacia, Pulmonary Edema
- Trial name
- BEAM (NCT00014989)
- Testing
- magnesium sulfate
- Where
- 17 sites in United States
- Volunteers
- 2,136 people
- Sponsor
- The George Washington University Biostatistics Center
Asthma in Children, Asthma Attack
Timely Administration of IV Magnesium Sulfate in Patients With a Moderate Asthma Exacerbation
This study aims to identify whether early administration of magnesium sulfate in moderate asthma exacerbations can potentially avoid admission, decrease length of stay in the emergency department (ED), decrease length of stay…
- Trial name
- NCT06137040
- Testing
- Magnesium Sulfate within the first hour, No Magnesium sulfate within the first hour
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Oklahoma
Postoperative Agitations in Pediatric Patients
Dexmedetomidine Versus Magnesium Infusion in Reducing Agitations in Pediatric Patients Undergoing Adenotonsillectomy
The aim of this study is evaluating the efficacy and safety of dexmedetomidine versus Magnesium for reducing emergence agitation after adenotonsillectomy in children.
- Trial name
- NCT05164627
- Testing
- Dexmedetomidine, Magnesium Sulphate, Normal saline
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Asthma
Nebulized Magnesium Sulfate in Children With Moderate to Severe Asthma
The purpose of this study is to investigate the use of magnesium sulfate nebulization in patient with moderate to severe asthma exacerbation in pediatric emergency.
- Trial name
- NCT01584726
- Testing
- Magnesium Sulfate
- Where
- 2 sites in Qatar
- Volunteers
- 400 people
- Sponsor
- Hamad Medical Corporation
Pre-Eclampsia
Impact of Body Mass Index on Serum Maternal and Fetal Magnesium Level
Magnesium sulphate is an inorganic salt with multiple therapeutic applications in medicine it has been widely utilized and studied on a diverse set of conditions such as asthma, cardiac arrhythmia and stroke.
- Trial name
- NCT03928691
- Testing
- Magnesium Sulfate
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Assiut University
Postoperative Pain
Magnesium Sulfate for TAP Analgesia During Laparoscopic Cholecystectomy
Study the effect of adding Magnesium sulfate to TAP block in analgesia after laparoscopic cholecystectomy.
- Trial name
- NCT02533284
- Testing
- Magnesium Sulfate, bupevecaine, saline
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University
Preeclampsia
Different Schemes of Magnesium Sulfate for Preeclampsia
Eclampsia is an obstetric emergency capable of prophylaxis. To prevent and control seizures, there is no doubt that the magnesium sulfate (MgSO4) is the ideal drug. However, there are still questions regarding its use and dose.
- Trial name
- MGSO4 (NCT02396030)
- Testing
- Magnesium sulfate 50% - 1g/h, Magnesium sulfate 50% - 2g/h
- Where
- Brazil
- Volunteers
- 62 people
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Bronchiolitis, Magnesium, Abnormal Blood Level
Efficacy of Magnesium Sulfate in the Treatment of Bronchiolitis
In this study, investigators will compare the efficacy and safety of intravenous (IV) Magnesium sulfate in decreasing bronchiolitis clinical severity score and the duration of hospitalization in admitted patients, as compared to…
- Trial name
- NCT02145520
- Testing
- Magnesium Sulfate
- Where
- Qatar
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Myofacial Pain, Trigger Points, Myofascial
Comparison Between Botox and Magnesium Sulfate Effect in Treatment of Myofascial Pain Trigger Points Within the Masseter Muscle
The goal of this randomized clinical trial is to compare the effectiveness of Botulinum toxin type A, magnesium sulfate and saline injections in treatment of the masseter muscle trigger points, in patients between 16 - 50 years…
- Trial name
- MPS MTrPs BTA (NCT06676475)
- Testing
- MgSO4, BOTOX-A
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Misr University for Science and Technology
Bronchial Asthma
Two Doses of the Intravenous Magnesium Sulfate Versus the Standard Single Dose ,With/ Without the Nebulized Budesonide For the Management of the Severe Asthma Exacerbation in the Emergency Room; A Randomized Controlled Trial.
Many studies have investigated the efficacy and safety of Intravenous magnesium sulfate and inhaled steroids in addition to the standard treatment for patients with severe asthma attacks.
- Trial name
- NCT02455687
- Testing
- Hi-dose iv MgSO4, Nebulized budesonide, Std-dose iv MgSO4
- Where
- Qatar
- Volunteers
- 240 people
- Sponsor
- Hamad Medical Corporation
Cardiac; Dysrhythmia, Postoperative, Congenital Heart Surgery
Prevention of Post-Operative Cardiac Arrhythmias
Aim 1: Primary Prevention of Post-operative Cardiac Arrhythmias 1. To evaluate the efficacy of dexmedetomidine vs. the combination of Magnesium Sulfate and dexmedetomidine for the prevention of post-operative cardiac arrhythmias…
- Trial name
- POCA (NCT04234906)
- Testing
- Dexmedetomidine, Magnesium Sulfate, Amiodarone
- Volunteers
- 870 people, healthy volunteers welcome
- Sponsor
- Jeffrey Moak