Clinical trials: Magnesium Sulfate
LIF LEVELS IN CORD BLOOD AND MATERNAL BLOOD DURING LABOR
Correlation Between LIF (Leukemia Inhibitory Factor ) Levels in Cord and Maternal Blood in Women Treated With Mg
During embryonic development, there are several cytokines such as: LIF (Leukemia inhibitory factor), ciliary neurotrophic factor (CNTF), epidermal growth factor family (EGF), neuregulin 1 (NRG1) and transforming growth factor β…
- Trial name
- NCT02507817
- Testing
- blood sample and tissue sample
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Pain
Epidural Magnesium Sulfate for Post-thoracotomy Pain Control
Pain after thoracotomy is very severe and may cause pulmonary complications. Thoracic epidural analgesia has greatly decreased the pain experience and its consequences.
- Trial name
- NCT03343548
- Testing
- magnesium sulfate, normal saline
- Where
- Iran
- Volunteers
- 80 people
- Sponsor
- National Research Institute of Tuberculosis and Lung Disease, Iran
Preeclampsia, Pregnancy Induced Hypertension
Labetalol Versus Magnesium Sulfate (MgSO4) for the Prevention of Eclampsia Trial
Eclampsia is a major cause of perinatal morbidity and mortality. The pathophysiology is not known but magnetic resonance imaging (MRI) and Doppler data suggest that overperfusion of the cerebral tissues is a major etiologic…
- Conditions
- Preeclampsia, Pregnancy Induced Hypertension, Gestational Hypertension, Chronic Hypertension
- Trial name
- LAMPET (NCT00293735)
- Testing
- labetalol (seizure prevention), MgSO4 (seizure prevention)
- Where
- 2 sites in United States, India
- Sponsor
- Baylor College of Medicine
Asthma in Children
Double Dose Magnesium Sulphate in Moderate-severe Asthma in Paediatrics
Introduction : . In Oman the prevalence of asthma was estimated to be 7.3% of adults and 12.7% of children . Magnesium sulphate is the second line treatment, many studies had shown that it has beneficial effect in treating acute…
- Trial name
- NCT04465175
- Testing
- Magnesium Sulfate
- Volunteers
- 90 people
- Sponsor
- Oman Medical Speciality Board
Analgesia
Intraperitoneal Analgesia in Pediatric Laparoscopy
It is important to keep children undergoing laparoscopic surgery pain free with rapid return to normal activity.
- Trial name
- NCT02820610
- Testing
- Dexmedetomidine, Magnesium Sulfate, Normal saline 0.9 %
- Where
- Egypt
- Volunteers
- 97 people
- Sponsor
- Assiut University
Hand, Foot and Mouth Disease
Magnesium Sulphate for Severe Hand, Foot and Mouth Disease in Vietnam
Hand foot and mouth disease (HFMD) is a common infectious disease caused by a number of different viruses - a small proportion of children infected with a particular type of enterovirus (EV71) develop neurological and systemic…
- Trial name
- NCT01940250
- Testing
- Magnesium Sulphate, Sterile water
- Where
- 2 sites in Vietnam
- Volunteers
- 26 people
- Sponsor
- Oxford University Clinical Research Unit, Vietnam
Postpartum Hemorrhage
Effect of Magnesium Sulphate Pre-exposure on Oxytocin-induced Contractility in Desensitized Human Myometrium - an in Vitro Study
Postpartum hemorrhage (PPH) is the loss of more than 500ml of blood within 24 hours after delivery. It is a major cause of maternal morbidity and mortality across the globe.
- Trial name
- NCT02647268
- Testing
- Oxytocin, Magnesium Sulphate
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Asthma in Children
Magnesium Sulfate in Bronchial Asthma and Acute Bronchiolitis in Children
Asthma is a prevalent disease that affects as many as334 million individuals worldwide, and is a major source of disability and premature death in children(1). Asthma affects 7.1 million children in the United States (2).
- Trial name
- NCT06955559
- Testing
- Magnesium sulfate
- Volunteers
- 60 people
- Sponsor
- Assiut University
Severe Preeclampsia
Effectiveness Study of Short Course of Magnesium Sulfate for Severe Preeclamsia
Magnesium sulfate is the ideal drug for seizures prophilaxis in preeclampsia. The ideal duration of this treatment after delivery is still to be established.
- Trial name
- MgSO4 (NCT01408979)
- Testing
- Magnesium sulfate 12 hours, Magnesium sulfate 24 hours
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Emergence Delirium
Effect of Intravenous Nalbuphine and Magnesium Sulfate on Emergence Agitation in Pediatric
Primary outcome: Measure The incidence of EA in children undergoing to hypospadias repair under general anesthesia is considered using Pediatric Anesthesia Emergence Delirium (PAED) scales.
- Trial name
- NCT06306040
- Testing
- Nalbuphine Versus Magnesium Sulfate
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Assiut University
Asthma
Nebulized Magnesium Sulfate in Children With Moderate to Severe Asthma
The purpose of this study is to investigate the use of magnesium sulfate nebulization in patient with moderate to severe asthma exacerbation in pediatric emergency.
- Trial name
- NCT01584726
- Testing
- Magnesium Sulfate
- Where
- 2 sites in Qatar
- Volunteers
- 400 people
- Sponsor
- Hamad Medical Corporation
Preeclampsia
Different Schemes of Magnesium Sulfate for Preeclampsia
Eclampsia is an obstetric emergency capable of prophylaxis. To prevent and control seizures, there is no doubt that the magnesium sulfate (MgSO4) is the ideal drug. However, there are still questions regarding its use and dose.
- Trial name
- MGSO4 (NCT02396030)
- Testing
- Magnesium sulfate 50% - 1g/h, Magnesium sulfate 50% - 2g/h
- Where
- Brazil
- Volunteers
- 62 people
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Anesthesia , Analgesia
Dexmedetomidine Versus Magnesium Sulfate in Ultrasound Guided Bilateral Bi-level Erector Spinae Plane Block in Corrective Scoliosis Surgery
Posterior spinal fusion for scoliosis surgery may lead to severe postoperative pain which requires significant opioid use for adequate perioperative analgesia.
- Trial name
- NCT05671081
- Testing
- Dexmedetomidine, Magnesium sulfate, Narcotic Analgesics
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Magnesium Sulfate Causing Adverse Effects in Therapeutic Use
Adding Magnesium Sulfate to Bupivacaine for Ilioinguinal and Iliohypogastric Nerve Block
Regional block of ilioinguinal and iliohypogastric (IIIH) nerves has been applied to provide postoperative analgesia after inguinal hernia repair.
- Trial name
- NCT05158647
- Testing
- normal saline, MgSo4
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Abdelrady S Ibrahim, MD
Brain Injuries, Head Injury
Magnesium Sulfate For Brain Injury
The purpose of the study is to determine whether magnesium sulfate, given within 8 hours of a moderate or severe traumatic brain injury improves survival, decreases the number of people developing seizures, improves the…
- Conditions
- Brain Injuries, Head Injury, Brain Concussion
- Trial name
- NCT00004730
- Testing
- magnesium sulfate
- Where
- United States
- Sponsor
- University of Washington
Cardiac; Dysrhythmia, Postoperative, Congenital Heart Surgery
Prevention of Post-Operative Cardiac Arrhythmias
Aim 1: Primary Prevention of Post-operative Cardiac Arrhythmias 1. To evaluate the efficacy of dexmedetomidine vs. the combination of Magnesium Sulfate and dexmedetomidine for the prevention of post-operative cardiac arrhythmias…
- Trial name
- POCA (NCT04234906)
- Testing
- Dexmedetomidine, Magnesium Sulfate, Amiodarone
- Volunteers
- 870 people, healthy volunteers welcome
- Sponsor
- Jeffrey Moak
Myofacial Pain, Trigger Points, Myofascial
Comparison Between Botox and Magnesium Sulfate Effect in Treatment of Myofascial Pain Trigger Points Within the Masseter Muscle
The goal of this randomized clinical trial is to compare the effectiveness of Botulinum toxin type A, magnesium sulfate and saline injections in treatment of the masseter muscle trigger points, in patients between 16 - 50 years…
- Trial name
- MPS MTrPs BTA (NCT06676475)
- Testing
- MgSO4, BOTOX-A
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Misr University for Science and Technology
Postoperative Pain
Comparing Intravenous Magnesium Sulfate With Dexamethasone as Adjuvants to Ultrasound Guided TAPblock
TAP block provided increased postoperative analgesia and reduced analgesic requirements as part of a multimodal analgesic regimen.
- Trial name
- TAPblock (NCT04223128)
- Testing
- Ultrasound guided transversus abdominis plane block
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tamer Nabil Abdelrahman
Pain, Postoperative
Magnesium Sulfate as an Adjuvant to Caudal Bupivacaine in Lower Abdominal Surgeries in Paediatrics.
Intravenous magnesium has been studied in pediatrics to reduce agitation after sevoflurane anesthesia in children undergoing adenotonsillectomy, reduce intraoperative rocuronium requirements, prevent laryngospasm and coughing…
- Trial name
- NCT03322878
- Testing
- Magnesium SO4
- Volunteers
- 90 people
- Sponsor
- Cairo University
Post Operative Arrythmia
Dexmedetomidine and Magnesium Sulfate in Preventing Junctional Ectopic Tachycardia After Pediatric Cardiac Surgery
to study the prophylactic effect of magnesium sulfate , dexmedetomidine or their combination in reduction the incidence of JETS postoperative
- Trial name
- NCT05554848
- Testing
- Dexmedetomidine, Magnesium sulfate
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Kasr El Aini Hospital