Clinical trials: Maintenance Hemodialysis
Diuretic Abuse
Use of Diuretics in Maintenance Hemodialysis Patients Undergoing Bioimpedance-guided Fluid Management
Background.The objective of the present study is to verify whether using diuretics will improve either blood pressure or fluid overload in maintenance hemodialysis patients with residual diuresis kidney function.
- Trial name
- NCT04182854
- Testing
- Furosemid hydrochlorothiazide
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Capital Medical University
Secondary Hyperparathyroidism
A Phase 3 Study of Etelcalcetide in Children With Secondary Hyperparathyroidism Receiving Hemodialysis
Assess the efficacy, safety, pharmacokinetics (PK) and pharmacodynamics (PD) of etelcalcetide in the treatment of secondary hyperparathyroidism (SHPT) in pediatric participants between ≥ 2 to < 18 years of age, with chronic…
- Trial name
- NCT03969329
- Testing
- Etelcalcetide
- Where
- 23 sites in Belgium, Czechia and 10 more
- Volunteers
- 24 people
- Sponsor
- Amgen
Hyperparathyroidism, Refractory Pruritus
The Effect and Safety of Hemodialysis and Hemoperfusion on Severe Renal Osteopathy and Itching in Uremia Patients
A prospective, randomized, controlled open clinic trial to evaluate the effect and safety of combination of conventional hemodialysis(HD) and hemoperfusion(HP) on middle molecules removal and complications improvement in…
- Conditions
- Hyperparathyroidism, Refractory Pruritus, Ostalgia, Insomnia
- Trial name
- NCT02747979
- Testing
- hemodialysis only, hemodialysis plus hemoperfusion(HA330), hemodialysis plus hemoperfusion(HA130)
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Sun Yat-sen University
Hemodialysis
Association of Survival in Impact of Ultrafiltration Rates in Hemodialysis Patients
This study assesses retrospectively the association of mortality on UFR assessments in our study population undergoing HD.
- Trial name
- NCT03471299
- Where
- Japan
- Volunteers
- 759 people, healthy volunteers welcome
- Sponsor
- University of Hyogo
End Stage Renal Failure on Dialysis
DiaSport - Endurance-orientated Training Program With Children and Adolescents on Maintenance Hemodialysis
Physical activity is considered essential for optimal health, development, socialization and well-being of children. However patients with end-stage renal disease (ESRD) are often restricted from participation in exercise…
- Trial name
- DiaSport (NCT01561118)
- Testing
- Bicycle-Ergometer Training
- Where
- Germany
- Volunteers
- 66 people
- Sponsor
- University Hospital, Bonn
Chronic Kidney Disease, Secondary Hyperparathyroidism
A Single-dose Study in Paediatric Patients Aged 2 to Less Than 18 Years With Secondary Hyperparathyroidism (sHPT) Receiving Haemodialysis
This is a study to evaluate the safety and pharmacokinetics in pediatric patients with secondary hyperparathyroidism receiving a single dose of etelcalcetide at the end of hemodialysis.
- Trial name
- NCT02833857
- Testing
- Etelcalcetide
- Where
- 13 sites in United States, Belgium and 4 more
- Volunteers
- 11 people
- Sponsor
- Amgen
Chronic Renal Failure, Hemodialysis
Effect of Homocysteine and Asymmetric Dimethylarginine on Cardiovascular Events in Hemodialysis Patients
Homocysteine (Hcy) and asymmetric dimethylarginine (ADMA) have recently been recognized as potential risk factors for atherosclerosis in the general population, and the metabolism of each of these substances seems to be closely…
- Conditions
- Chronic Renal Failure, Hemodialysis, Atherosclerosis
- Trial name
- NCT00161369
- Where
- Japan
- Volunteers
- 200 people
- Sponsor
- University of Shizuoka
Secondary Hyperparathyroidism, Chronic Kidney Disease
A Trial of Etelcalcetide in Pediatric Participants With Secondary Hyperparathyroidism and Chronic Kidney Disease on Hemodialysis
This is a phase 3 trial of etelcalcetide in pediatric participants with secondary hyperparathyroidism (SHPT) and chronic kidney disease (CKD) on hemodialysis.
- Trial name
- NCT03633708
- Testing
- Etelcalcetide, Standard of Care
- Where
- 43 sites in United States, Argentina and 8 more
- Volunteers
- 56 people
- Sponsor
- Amgen
Hyperphosphatemia, Maintenance Hemodialysis
Tenapanor in Maintenance Hemodialysis Patients
The investigators hypothesize that Tenapanor can improve serum phosphorus control and regulate intestinal metabolism in maintenance hemodialysis patients without increasing the risk of severe gastrointestinal adverse events.
- Trial name
- NCT07882017
- Testing
- Tenapanor
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Huashan Hospital
End Stage Renal Failure on Dialysis, Periodontitis
Effect of Non-Surgical Periodontal Therapy on Serum Albumin Levels of Patients on Maintenance Hemodialysis Therapy,
Periodontitis is a destructive chronic infection of the gums, ligaments, and bone, predominantly caused by Gram-negative bacteria. Individuals with periodontal disease are at increased risk of systemic diseases.
- Trial name
- NCT01641757
- Testing
- non-surgical periodontal therapy
- Where
- Pakistan
- Volunteers
- 160 people
- Sponsor
- University of the Punjab
Chronic Kidney Disease (CKD), Secondary Hyperparathyroidism
A Study of PLS240 in Pediatric Participants With Secondary Hyperparathyroidism and Chronic Kidney Disease on Hemodialysis
Approximately 56 participants who are 1 month old to 17 years old will be enrolled in this study. The total duration for this study will be 38 weeks (or up to 42 weeks when participants require a washout period due to prior…
- Trial name
- NCT07890584
- Testing
- PLS240, Standard of Care
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Pathalys Pharma
Hepatitis E Virus Infection
Epidemiological Study of Hepatitis E Virus in Maintenance Hemodialysis Patients
Primary Purpose: 1. Evaluate the prevalence and incidence of HEV infection in MHD patients. 2. Compare differences of the prevalence and incidence between the MHD patients and the control. .
- Trial name
- MHD HEV (NCT02645955)
- Volunteers
- 436 people, healthy volunteers welcome
- Sponsor
- Xiamen University
Uremic Xerosis
Efficacy, Local Tolerance and Patient Acceptability of a Moisturizing Emollient in Patients With Uremic Xerosis
To evaluate the palliative effects of a moisturising emollient, in patients with uremic xerosis of moderate, severe or very severe intensity, associated or not to uremic pruritus.
- Trial name
- NCT01084720
- Testing
- V0034 CR
- Volunteers
- 100 people
- Sponsor
- Orfagen
Sodium Zirconium Cyclosilicate, Hyperkalemia
Sodium Zirconium Cyclosilicate Lowers Hyperkalemia After Parathyroidectomy
Sodium zirconium cyclosilicate (SZC) has been demonstrated for its serum potassium-lowering efficacy and safety in hyperkalemia hemodialysis patients. However, the effects of SZC during the perioperative period remained unknown.
- Conditions
- Sodium Zirconium Cyclosilicate, Hyperkalemia, Hyperparathyroidism, Secondary
- Trial name
- SZC (NCT05382988)
- Testing
- Sodium zirconium cyclosilicate
- Volunteers
- 62 people
- Sponsor
- Guangdong Provincial People's Hospital
Anemia
Study of the Safety and Efficacy of Ferrlecit® Maintenance Dosing in Pediatric Hemodialysis Patients
A phase 4 clinical investigation in iron-replete pediatric hemodialysis patients, whose legal guardian had provided signed informed consent, and who had satisfied the inclusion and exclusion criteria of the study.
- Trial name
- NCT00224003
- Testing
- Sodium Ferric Gluconate Complex in Sucrose.
- Where
- 10 sites in United States
- Volunteers
- 23 people
- Sponsor
- Watson Pharmaceuticals
Renal Anemia
Study to Determine Optimum Intravenous Starting Dose of MIRCERA for Treatment of Pediatric Participants With Anemia and Chronic Kidney Disease on Hemodialysis
This sequential study will assess the efficacy and safety of multiple doses of intravenous (IV) methoxy polyethylene glycol-epoetin beta (MIRCERA), and will determine the optimum starting dose for maintenance treatment of anemia…
- Trial name
- NCT00717366
- Testing
- Methoxy Polyethylene Glycol-Epoetin Beta
- Where
- 39 sites in Australia, Belgium and 10 more
- Volunteers
- 64 people
- Sponsor
- Hoffmann-La Roche