Clinical trials: Major Depression
Depressive Disorder, Mood Disorder
Family Based Treatment of Depressed Adolescents (AHUS)
Major depressive disorder (MDD) affects about 5% of adolescents and is on the rise both internationally and in Norway. Further, it is also associated with increased risk for suicide.
- Conditions
- Depressive Disorder, Mood Disorder, Major Depression
- Trial name
- BudFam2 (NCT01830088)
- Testing
- Attachment Based Family Therapy, Enhanced Usual Care
- Where
- Norway
- Volunteers
- 62 people
- Sponsor
- University Hospital, Akershus
Bipolar Disorder, Major Depressive Disorder
The Gut Microbiota of Bipolar and Depression
Background: The gut microbiome is emerging as an important factor in regulating mental health yet it remains unclear what the target should be for psychiatric treatment.
- Trial name
- NCT03062332
- Testing
- Faecal genome
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Schizophrenia, Bipolar Disorder
Multi-modal Assessment of Gamma-aminobutyric Acid (GABA) Function in Psychosis
The purpose of this study is to better understand mental illness and will test the hypotheses that, while viewing affective stimuli, patient groups will show increased blood oxygenation level dependent (BOLD) signal by fMRI after…
- Conditions
- Schizophrenia, Bipolar Disorder, Healthy, Psychosis
- Trial name
- GABAmech (NCT04004416)
- Testing
- Lorazepam and fMRI
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Depression - Major Depressive Disorder
Designing and Pilot Testing a Just-in-time Adaptive Intervention (JITAI) for Adolescent Depression Treatment in Primary Care
The goal of this clinical trial is to learn if a tailored smartphone intervention called Sidekick can help improve sleep and physical activity for teenagers in depression treatment.
- Trial name
- NCT06875726
- Testing
- Sidekick
- Volunteers
- 30 people
- Sponsor
- University of Washington
Depressive Disorder
Prevention of Adolescent Major Depression
The main purpose of this study is to assess the effect of a cognitive group intervention on prevention of major depression in 14-15-year-old adolescents.
- Trial name
- CWSA-Fin (NCT00611052)
- Testing
- the Adolescent Coping with Stress, Treatment as usual, usual health education
- Where
- 3 sites in Finland
- Volunteers
- 65 people
- Sponsor
- Finnish Institute for Health and Welfare
Depressive Symptoms, Remited Major Depressive Disorder
Cognitive Control Emotion Training to Prevent Major Depression in Youth At-Risk
The goal of this clinical trial is to learn if intervention of positive emotion working memory (PEWM), or negative emotion working memory (NEWM), or positive attention bias training (PABT) can prevent major depressive disorder…
- Trial name
- CTE 2019 (NCT04346784)
- Testing
- positive emotion working memory(PEWM) training, negative emtion working memory(NEWM) training, PABT
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Hunan Normal University
Depression
Evaluation of the H1-Coil TMS- Double Blind Placebo Controlled Study in Adolescent Patients Suffering From Major Depression
This study is a randomized double blind placebo controlled EEG monitored study of deep rTMS treatment to treat adolescent depression.
- Trial name
- NCT03541707
- Testing
- Deep TMS Brainsway's H coil
- Where
- Israel
- Volunteers
- 52 people
- Sponsor
- Shalvata Mental Health Center
Depression - Major Depressive Disorder
Selenium Supplementation for Improving Depression in Children and Adolescents: Efficacy and Mechanistic Study
The purpose of this study is to investigate the role and mechanisms of selenium in depression among children and adolescents, aiming to provide new insights for understanding the pathogenesis and treatment of depression in this…
- Trial name
- NCT07203144
- Testing
- selenium yeast supplementation
- Where
- China
- Volunteers
- 172 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Major Depressive Disorder, Depression
Is Brain Insulin Resistance a Feature of the Biology of Depression in Adolescents
This study will examine if brain insulin resistance is a feature of depression in humans using magnetic resonance imaging (MRI) measures sensitive to brain insulin action.
- Trial name
- NCT05571878
- Testing
- Humalog, Saline nasal spray
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health