Clinical trials: Major Depression Moderate
Major Depressive Disorder
Efficacy and Cost-effectiveness of Internet-delivered CBT for Adolescents With Depression
Adolescent depression is a prevalent and impairing condition that can be effectively treated with Cognitive Behavior Therapy (CBT). However, a majority of adolescents do not have access to CBT.
- Trial name
- IDA (NCT04977856)
- Testing
- Behavioral activation (BA), Regular care within primary or secondary mental health care for children
- Where
- Sweden
- Volunteers
- 219 people
- Sponsor
- Region Stockholm
Depressive Disorder, Major
Aerobic Versus Leisure Group for Adolescents With Depression
The aim is to evaluate aerobic group exercise versus leisure group activities in adolescents with mild to moderate depression. Primary outcome is Children's Depression Rating Scale - Revised (CDRS-R).
- Trial name
- NCT05076214
- Testing
- Aerobic exercise in group, Leisure activities in group
- Where
- 4 sites in Sweden
- Volunteers
- 122 people
- Sponsor
- Lund University Hospital
Infant, Newborn, Hypoxia, Brain
Preemie Hypothermia for Neonatal Encephalopathy
This study is a randomized, controlled trial to assess safety and effectiveness of whole body hypothermia for 72 hours in preterm infants 33-35 weeks gestational age (GA) who present at <6 hours postnatal age with moderate to…
- Conditions
- Infant, Newborn, Hypoxia, Brain, Hypoxia-Ischemia, Brain, Encephalopathy, Hypoxic-Ischemic
- Trial name
- NCT01793129
- Testing
- Hypothermia, Normothermic Control
- Where
- 18 sites in United States
- Volunteers
- 168 people
- Sponsor
- NICHD Neonatal Research Network
Depression, Suicide and Self-harm
Telehealth Behavioral Activation for Teens
Behavioral activation is one such empirically supported intervention. Derived from cognitive-behavioral therapy, a well-established treatment for depression, behavioral activation uses psychoeducation and skill-building to…
- Conditions
- Depression, Suicide and Self-harm, Depression in Adolescence, Depression Mild
- Trial name
- NCT06273995
- Testing
- Behavioral Activation
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Baylor College of Medicine
Depressive Disorder, Major
Aerobic Group Exercise for Adolescents With Depression
The aim is to evaluate aerobic group exercise versus leisure group activities in adolescents with mild to moderate depression. Primary outcome is Children's Depression Rating Scale - Revised (CDRS-R).
- Trial name
- NCT04695145
- Testing
- Aerobic exercise in group, Group sessions with leisure activities
- Where
- Sweden
- Volunteers
- 14 people
- Sponsor
- Lund University Hospital
Depressive Symptoms Mild to Moderate in Severity, Major Depressive Disorder
Adolescent Interpersonal Counseling in Primary Care
The demand for prevention and treatment of adolescent depression has rapidly increased over years. A national project to improve treatment of adolescent depression in primary care has taken place in Finland starting 2020.
- Trial name
- NCT06390462
- Testing
- Interpersonal counseling, Treatment as usual, No support, intervention or other treatment
- Where
- 4 sites in Finland
- Volunteers
- 9,000 people, healthy volunteers welcome
- Sponsor
- Finnish Institute for Health and Welfare
Depressive Disorder, Major
Alpha-Stim AID and Major Depressive Disorder
The study will be a multi-centre parallel group, double blind, non-commercial, randomised controlled superiority trial. Study participants will be referred from Primary Care GP practices via their GP and randomised into active…
- Trial name
- NCT04963907
- Testing
- Active Alpha-Stim CES
- Where
- United Kingdom
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Electromedical Products International, Inc.
Depression, Clinical Depression
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Depression
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records
- Conditions
- Depression, Clinical Depression, Depression, Anxiety, Depression, Postpartum
- Trial name
- NCT04211467
- Testing
- No Intervention
- Where
- United States
- Sponsor
- ProgenaBiome
Major Depressive Disorder
Feasibility of Internet-delivered CBT for Adolescents With Depression
Prior to a properly powered randomized controlled study, evaluating efficacy and cost-effectiveness of ICBT, we will conduct a pilot study to investigate if the trial design is feasible, if therapist-guided and self-guided…
- Trial name
- NCT04117789
- Testing
- Therapist-guided internet-delivered cognitive behavior therapy for depression in adolescents, Self-guided internet-delivered cognitive behavior therapy for depression in adolescents, Treatment as usual
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Karolinska Institutet
Atopic Dermatitis
The Impact of Dupilumab Treatment on Anxiety and Depression Symptoms in Patients With Moderate-to-Severe Atopic Dermatitis
This study aims to assess the impact of dupilumab on the mental health and quality of life of moderate-to-severe Atopic Dermatitis (AD) patients.
- Trial name
- DERMIND-AD (NCT07467564)
- Testing
- Dupilumab
- Where
- 7 sites in Qatar, Saudi Arabia and 1 more
- Volunteers
- 184 people
- Sponsor
- Sanofi
Major Depression Moderate, Feasibility Studies
rTMS for Youth Inpatients With Depression
Youth aged 15-24 are likelier to have depression than all age groups in Canada. One-third of depressed youth do not respond to psychotherapy and/or antidepressant medications.
- Trial name
- NCT07140575
- Testing
- repetitive transcranial magnetic stimulation (rTMS)
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Sunnybrook Health Sciences Centre