Clinical trials: Malnutrition
Hypophosphatasia
Expanded Access Program for Asfotase Alfa Treatment for Patients With Infantile- or Juvenile-onset Hypophosphatasia (HPP)
This clinical trial is being conducted in Hypophosphatasia, a bone disorder caused by gene mutation(s) resulting in bone defects. These gene mutations cause low levels of an enzyme needed to harden bone.
- Trial name
- NCT02496689
- Testing
- asfotase alfa
- Where
- 5 sites in United States, France
- Sponsor
- Alexion Pharmaceuticals, Inc.
Malnutrition
Women's Work in Agriculture and Infant Nutrition
Background Over the last 10 years there has been an increase in the female agriculture labour force, in Pakistan, resulting in a feminisation of agriculture; which could have either a positive or negative impact on maternal and…
- Trial name
- WWAN (NCT03406182)
- Where
- 2 sites in Pakistan, United Kingdom
- Volunteers
- 1,161 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Malnourished Children, Stunting of Growth
Comprehensive Nutritional Support for Children in Zambia (ZamCNC) - A Pilot Investigation
In a recently completed intervention study, more than 50% of children in Lusaka were found to be stunted by age two, even when nutritional supplements were provided.
- Trial name
- ZamCnC (NCT07153913)
- Testing
- Intensive growth support
- Where
- Zambia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Günther Fink
Other Preterm Infants, Vitamin D Deficiency
The Effect of Vitamin D Administration to Premature Infants on Vitamin D Status and Respiratory Morbidity
This trial objective is to assess whether doubling the daily intake of vitamin D improves serum vitamin D levels and serves as primary prevention of respiratory infections and asthma in premature infants.
- Conditions
- Other Preterm Infants, Vitamin D Deficiency, Bronchiolitis, Asthma
- Trial name
- NCT02404623
- Testing
- Vitamin D
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Severe Acute Malnutrition
Efficacy and Acceptability of RUTFs in Indonesia
Severe wasting or Severe Acute Malnutrition (SAM) continues to be a major public health problem in Indonesia, affecting more than 2 million children under 5 years old.
- Trial name
- NCT05614505
- Testing
- Ready to use therapeutic foods
- Where
- Indonesia
- Volunteers
- 300 people
- Sponsor
- Institut de Recherche pour le Developpement
Vitamin D Deficiency
Impact of Vitamin D Status on Bones in Breastfed Infants
Vitamin D deficiency is widespread and linked to decreased bone mineral content. Little data exists regarding the vitamin D status and the relationship of 25-hydroxyvitamin D (25-OHD) status to functional bone health outcomes in…
- Trial name
- NCT00697294
- Testing
- Tri-Vi-Sol
- Where
- 3 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
X-Linked Hypophosphatemia
A Study to Describe the Lived Experience of XLH for Adolescents at End of Skeletal Growth
An observational, prospective, mixed-methods study involving the integration of quantitative and qualitative data exploring the lived experience of burosumab-treated adolescents with XLH at the end of skeletal growth.
- Trial name
- NCT05181839
- Testing
- Burosumab
- Where
- 14 sites in France, Germany and 3 more
- Volunteers
- 25 people
- Sponsor
- Kyowa Kirin Pharmaceutical Development Ltd
Malnourished Children
Effect Of Probiotics Supplementation on Outcome Of Malnourished Children
The Outcome Of malnourished children who receive probiotics (Lactobacillus and Bifidobacterium
- Trial name
- NCT06606951
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hypovitaminosis D
Vitamin D Status and the Adequacy of Vitamin D Intake in Early Preterm Infants
Vitamin D is an essential nutrient. Deficiency of vitamin D is widespread. The prevalence of vitamin D deficiency in early preterm infants is unknown.
- Trial name
- NCT01793402
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Cardiovascular Diseases, Diabetes Mellitus, Type 2
Healthy Lifestyle Promotion Program in Communities From the Yaqui Valley
The aim is to evaluate the change in indicators of lifestyle and its effect on cardiometabolic biomarkers as a response to an integrative mother-child intervention to promote healthy lifestyles and prevent food insecurity and…
- Trial name
- NUTRIGANDO (NCT05945862)
- Testing
- NUTRIGANDO
- Where
- Mexico
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Instituto Tecnologico de Sonora
Helminthiasis
Relative Efficacy of Two Regimens of Ante-helminthic Treatment
The most common soil transmitted helminthic infections(STHI) includes infection with Ascaris lumbricoides, Trichuris trichiura, and Hookworm.
- Trial name
- NCT00367627
- Testing
- Albendazole
- Where
- Bangladesh
- Volunteers
- 200 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Malnourished Children
Zinc Absorption From Zinc Biofortified Rice
a. To measure the amount of zinc absorbed from ZnBfR compared with the amount absorbed from CR and from CR fortified with added zinc, using the triple stable isotope tracer ratio technique in young children.
- Trial name
- NCT01346722
- Testing
- Diet-ZnBfR, Diet- CR, CR + Zn
- Where
- Bangladesh
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Pediatric Cancer, Nutrition Related Cancer
Pediatric Oncology Nutrition Intervention Trial
Nearly 60% of pediatric patients diagnosed with cancer develop malnutrition caused by a combination of disease burden, side effects of chemotherapy, and the intensity of cancer treatment.
- Conditions
- Pediatric Cancer, Nutrition Related Cancer, Nutrition Aspect of Cancer, Muscle Loss
- Trial name
- POINT (NCT06175273)
- Testing
- Oral Nutrition Supplement, Tube Feed, Cyproheptadine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Corey Hawes
Vitamin D Deficiency
Vitamin D Deficiency Still Growing
Vitamin D deficiency has become one of the most prevalent health problems in modern society. However, there has been no study that has reported the trend of vitamin D status in Asia.
- Trial name
- NCT03304795
- Volunteers
- 39,759 people, healthy volunteers welcome
- Sponsor
- DongGuk University
Malnutrition, Stunting
Early Life Interventions for Childhood Growth and Development In Tanzania
This study aims to assess growth and cognitive effects of treatment with azithromycin and nitazoxanide and/or nicotinamide (vitamin B3) supplementation nicotinamide.
- Conditions
- Malnutrition, Stunting, Cognitive Development, Enteric Pathogens
- Trial name
- ELICIT (NCT03268902)
- Testing
- Azithromycin Oral Liquid Product, Nitazoxanide Oral Suspension, Nicotinamide
- Where
- Tanzania
- Volunteers
- 1,188 people
- Sponsor
- Haydom Lutheran Hospital
Cerebral Palsy (CP), Malnutrition in Children
Assessment of Nutritional Status Using Mid-Upper Arm Circumference Z-Score in Children With Cerebral Palsy
Children with cerebral palsy are at increased risk of malnutrition due to motor impairment, feeding difficulties, and chronic health problems.
- Trial name
- NCT07351695
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Muğla Sıtkı Koçman University
Diarrhea, Malnutrition
Randomized, Controlled Trial - Lactoferrin Prevention of Diarrhea in Children
Much has been learned in recent years about the mechanisms by which breastfeeding improves child health and survival. However, there has been little progress in using these insights to improve pediatric care.
- Trial name
- NCT00560222
- Testing
- bovine lactoferrin
- Where
- Peru
- Volunteers
- 555 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Anemia, Malnutrition
Home Fortification of Complementary Foods in Bihar India
This study evaluates the program effectiveness of home fortification along with infant and young child feeding (IYCF) counseling as a strategy to address anemia and complementary feedings gaps in a program setting of the…
- Trial name
- NCT02593136
- Testing
- Home Fortification Product (HFP), Infant and Young Child Feeding (IYCF) Practices Counseling
- Where
- India
- Volunteers
- 11,861 people
- Sponsor
- Emory University
Chronic Kidney Disease stage3, Chronic Kidney Disease stage4
Phase 3 Safety and Efficacy Study of CTAP101 Extended-release Capsules in Children With Secondary Hyperparathyroidism
This is a phase 3, multi-center, randomized, double-blind, placebo-controlled study in children with stage 3-4 chronic kidney disease (CKD), secondary hyperparathyroidism (SHPT) and vitamin D insufficiency.
- Conditions
- Chronic Kidney Disease stage3, Chronic Kidney Disease stage4, Vitamin d Deficiency, Secondary Hyperparathyroidism
- Trial name
- NCT05543928
- Testing
- CTAP101
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- OPKO Health, Inc.
Vitamin A Deficiency, Iron-deficiency
Impact of Food-to-Food Fortified Cereal Products on Diet Quality in Eldoret, Kenya
The overall hypotheses is that a product designed with optimized nutritional characteristics, based on consumer preferences and leveraging local nutrient dense ingredients, can successfully deliver nutrition through sustainable…
- Trial name
- KenyaMPS (NCT05882682)
- Where
- Kenya
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Purdue University
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