Clinical trials: Management, Medication Therapy
Quality of Life, Injection Site Reaction
Simultaneous mRNA COVID-19 and IIV4 Vaccination Study
This study is a prospective, randomized clinical trial. During this study, participants will be randomly assigned to receive quadrivalent inactivated influenza vaccine (IIV4) and mRNA COVID-19 vaccine either simultaneously or…
- Conditions
- Quality of Life, Injection Site Reaction, Adverse Drug Event, Systemic Reaction
- Trial name
- NCT05028361
- Testing
- mRNA COVID-19, IIV4
- Where
- 3 sites in United States
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Duke University
Trachoma, Lymphatic Filariasis
Safety Study of Combined Azithromycin, Ivermectin and Albendazole for Trachoma and Lymphatic Filariasis
Trachoma and lymphatic filariasis (LF) are two 'Neglected Tropical Diseases' (NTDs), infectious diseases that affect millions of poor people in countries in the developing world.
- Trial name
- AZIVAL2 (NCT01903057)
- Testing
- azithromycin, ivermectin, albendazole
- Where
- Mozambique
- Volunteers
- healthy volunteers welcome
- Sponsor
- Emory University
Glaucoma, Dry Eye Syndrome
Eye Drop Use in Glaucoma Patients Through Patient Surveys and Video Observations
This study will be used to evaluate how patients put eye drops in their eyes and any problems that may arise from this activity.
- Conditions
- Glaucoma, Dry Eye Syndrome, Conjunctivitis
- Trial name
- NCT00522600
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Robin, Alan L., M.D.
Lymphatic Filariases
Prevalence Studies After Triple Drug Therapy for Lymphatic Filariasis
This study will assess the impact of 2-drug (DA) or 3-drug (IDA) regimens on lymphatic filariasis infection parameters in communities.
- Trial name
- NCT03352206
- Testing
- 2 drug dose - DA, 3 drug dose - IDA
- Where
- 5 sites in Fiji, Haiti and 3 more
- Volunteers
- 20,092 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Childhood Mortality
Neonates and Azithromycin, an Innovation in the Treatment of Children in Burkina Faso
Although under-5 mortality rates are declining globally, neonatal mortality remains persistently high in many regions of sub-Saharan Africa.
- Trial name
- NAITRE (NCT03682653)
- Testing
- Azithromycin
- Where
- Burkina Faso
- Volunteers
- 21,832 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Chemotherapy
Educational Program's Impact on Nurses' Skills in Port-A-Catheter Care for Chemotherapy Patients
The goal of this experimental study is to evaluate if an educational intervention can improve nurses' knowledge and practice in caring for patients with implanted Port-A-Catheters among oncology nurses directly involved in…
- Trial name
- NCT06664476
- Testing
- PortCare Professional Training Program
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dengue
Immunogenicity and Safety of Tetravalent Dengue Vaccine (TDV) in Adolescents in Non-Endemic Area(s)
The purpose of this study was to describe the neutralizing antibody response against each dengue serotype at 1 month post second dose of TDV or placebo in dengue-naive adolescent participants.
- Trial name
- NCT03341637
- Testing
- Tetravalent Dengue Vaccine (TDV)
- Where
- 5 sites in Mexico
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Takeda
Helminth Infection
Intestinal Microbiome Post-Azythromycin/Albendazole Treatment
Molecular testing of the gut microbiome and enteric pathogens is rapidly moving beyond targeted PCR testing to next generation sequencing techniques.
- Trial name
- NCT03032042
- Testing
- Azithromycin, Albendazole, Delayed treatment
- Where
- Ethiopia
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Medication Compliance, Contraception
Adolescent Subcutaneous (SQ) Injection Video Validation
This is a study to determine if a video that utilizes a peer to teach self administration of subcutaneous depot medroxyprogesterone is both effective and well accepted by adolescent patients who are already receiving ongoing…
- Conditions
- Medication Compliance, Contraception, Self-Evaluation
- Trial name
- NCT04997499
- Testing
- watch an instructional video
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Lymphatic Filariasis
Optimization of MDA With Existing Drug Regimens for LF: Monitoring Efficacy of Ongoing Treatment Programs in PNG
The standard regimen for elimination of lymphatic filariasis (LF) in PNG is annual administration of two drugs at the same time.
- Trial name
- MDA (NCT03268252)
- Where
- Papua New Guinea
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Interactive Voice Response (IVR)
Treatment Follow-up Study
This study will assess the effectiveness of a medication safety monitoring method utilizing interactive voice response technology for youth recently prescribed anti-depressant medication.
- Trial name
- PhaST (NCT00995696)
- Testing
- PhaST IVR Calls
- Where
- 2 sites in United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Lymphatic Filariasis, Scabies
Better Options for Lymphatic Filariasis Treatment
The goal of this clinical trial is to learn if mass drug administration with moxidectin in combination with diethylcarbamazine, and albendazole (MoxDA) can treat lymphatic filariasis, scabies and strongyloidiasis in children and…
- Conditions
- Lymphatic Filariasis, Scabies, Strongyloidiasis
- Trial name
- BOLT (NCT07159373)
- Testing
- MoxDA - Moxidectin + Diethylcarbamzine (DEC) + Albendazole, IDA - Ivermectin + DEC + albendazole
- Where
- Fiji
- Volunteers
- 5,100 people, healthy volunteers welcome
- Sponsor
- Medicines Development for Global Health
Vaccines, Pneumococcal, Infant
Study Evaluating Treatment of Fever in Children Who Have Been Vaccinated With Prevenar and Infanrix Hexa
The purpose of the study is to determine whether prophylactic antipyretic treatment after vaccination with Prevenar and a concomitant hexavalent DTPa combination vaccine reduces the rate of febrile reactions.
- Conditions
- Vaccines, Pneumococcal, Infant, Fever, Chemically Induced, Drug Therapy, Combination
- Trial name
- NCT00294294
- Testing
- Prevenar, Infanrix hexa
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Chronic Pain (back / Neck)
Impact of a Pain Neuroscience Education Program on Primary Students with and Without Intellectual Disabilities
This observational study evaluates the impact of a Pain Neuroscience Education (PNE) program on primary school students in Extremadura, Spain.
- Trial name
- NCT06664606
- Testing
- Pain Neuroscience Education Program (PNE)
- Where
- Spain
- Volunteers
- 413 people, healthy volunteers welcome
- Sponsor
- Universidad de Extremadura
Pain
Art Therapy Pain Management Adolescents Pediatric ED
This project is studying adolescents between the ages of 12 to 18 years that come to the emergency department and are in pain. We want to find out how well art therapy is able to decrease the pain they are experiencing.
- Trial name
- NCT03755687
- Testing
- Art Therapy Intervention
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Columbia University
Status Epilepticus
Improving Emergency Management of Status Epilepticus
In the trial the effectiveness of pre-briefing physicians with the current guideline on Status epilepticus (SE) treatment or a consolidated "one page" guideline regarding quality enhancement of the physician's clinical…
- Trial name
- SESIM (NCT03883516)
- Testing
- Pre-briefing with the current SE treatment guidelines, Pre-briefing with a consolidated "one page" SE treatment guide, No Pre-briefing
- Where
- Switzerland
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Health Education
Dentists' Understanding of Diagnostic Test Results and Treatment Efficacy.
There is little evidence on how best to present diagnostic and treatment effect information to dentists and whether this makes any difference to their understanding of the information given and clinical management.
- Trial name
- RCDENT2017 (NCT03051295)
- Testing
- Dental health information form
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Musculoskeletal Pain, School Health
Effectiveness of Health Education Program on Musculoskeletal Pain Management in Primary School Students
Musculoskeletal pain during childhood can negatively affect school attendance, physical activity, and social participation. This study will evaluate the effectiveness of the school-based health education program 'SocLaLola'…
- Conditions
- Musculoskeletal Pain, School Health, Sedentary Behaviors, Health Education
- Trial name
- LOLA (NCT07160478)
- Testing
- School Health Program
- Where
- Spain
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Universitat de Lleida
HIV Infections, Breast Cancer
The MARVIN Chatbots to Provide Information for Different Health Conditions
This research is a continuation of a usability study with the MARVIN chatbot. The investigators aim to adapt the MARVIN chatbot to open it to other health domains (e.g. breast cancer) and populations (e.g. pharmacists).
- Conditions
- HIV Infections, Breast Cancer, Pediatric Emergency Medicine
- Trial name
- NCT05789901
- Testing
- MARVIN, MARVIN-Pharma, MARVINA
- Where
- 2 sites in Canada
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Attention Deficit Hyperactivity Disorder (ADHD)
Follow up Treatment of Children With Attention Deficit Hyperactivity Disorder (ADHD)
The purpose of the study is to examine how well two types of treatment follow up work compared to one another: 1. standard community follow up 2. medication monitoring plus tailored case management follow up.
- Trial name
- NCT02142140
- Testing
- Academic and Organization skills, Parent Training, Social Skills Training
- Where
- 2 sites in Canada
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre