Clinical trials: Manipulation, open to volunteers
Neuroblastoma, Rhabdomyosarcoma
Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors
Hematopoietic stem cell transplantation can cure patients with blood cancer and other underlying diseases. αβ-T cell and B cell depletion has been introduced to decrease GVHD and PTLD and has demonstrated effectiveness for…
- Conditions
- Neuroblastoma, Rhabdomyosarcoma, Synovial Sarcoma, Peripheral Nerve Sheath Tumors
- Trial name
- NCT06625190
- Testing
- Miltenyi CliniMACS Prodigy ® system, Zoledronic acid
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Florida
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia
Alpha/Beta T Cell and CD19+ B Cell Depletion in Allogeneic Stem Cell Transplantation in Patients With Malignant Diseases
This study will assess the safety, efficacy, and feasibility of ⍺/β CD3+ T-cell and CD19+ B-cell depletion in allogeneic stem cell transplantation in patients with acute lymphocytic leukemia (ALL), acute myeloid leukemia (AML)…
- Conditions
- Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Juvenile Myelomonocytic Leukemia, Myelodysplastic Syndromes
- Trial name
- NCT05800210
- Testing
- Miltenyi CliniMACS Prodigy ® system
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Florida
Neurologic Disorder
Effect of Using an Object Handling Serious Game on Upper Limb Rehabilitation for Children with Neurological Disorders
Cerebral palsy, and more broadly neurological disorders, can lead to significant motor impairments that impact individuals' daily lives.
- Trial name
- NCT06866730
- Testing
- Serious game
- Where
- 2 sites in France
- Volunteers
- 10 people
- Sponsor
- Fondation Ellen Poidatz
Otitis Media, Otitis Media Effusion
Osteopathic Manipulative Treatment for Children With Chronic or Recurrent Otitis Media
The goal of this clinical trial is to learn whether osteopathic manipulative treatment, or OMT, can reduce the need for tympanostomy tube surgery in children with recurrent or chronic otitis media who have been referred to an…
- Conditions
- Otitis Media, Otitis Media Effusion, Otitis Media Recurrent, Otitis Media With Effusion in Children
- Trial name
- NCT07639775
- Testing
- Experimental Osteopathic Manipulative Treatment (OMT) Protocol, Control Osteopathic Manipulative Treatment (OMT) Protocol
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Sarah Vidal
Scoliosis
Biomechanical Study of Lever Positioning Manipulation on Scoliosis
Research background Scoliosis is a common three-dimensional spinal deformity, especially in adolescents. In severe cases, it can lead to thoracic deformation and cardiopulmonary dysfunction.
- Trial name
- NCT07325045
- Testing
- Lever positioning manipulation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Ankyloglossia, Breastfeeding Support
Post-Procedural Manual Manipulation for Infant Ankyloglossia
The goal of this randomized control trial is to determine the impact of post-frenotomy manual manipulation on revision rates and breastfeeding outcomes.
- Trial name
- NCT06830148
- Testing
- Post-frenotomy manual manipulation
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Georgetown University
Neonatal Disorder
Impact of Tactile Kinesthetic Stimulation and Soft Tissue Manipulation on Cortisol in Preterm
Effect of Soft tissue Therapy in managing Procedural Pain among neonates admitted to the neonatal intensive care unit. This study focuses on procedural pain management with the help of Soft tissue manipulation, which includes…
- Trial name
- NCT06845137
- Testing
- Tactile-Kinesthetic Stimulation (TKS) and Soft Tissue Manipulation (STM), Standard Therapy
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- faizan kashoo, PT
Pediatric Procedural Sedation
Intranasal Dexmedetomidine vs. Oral Chloral Hydrate for Pediatric Orthopedic Procedural Sedation
This prospective randomized controlled study will compare the effectiveness and safety of intranasal dexmedetomidine with oral chloral hydrate for procedural sedation in children undergoing painful orthopedic manipulation.
- Trial name
- NCT07768566
- Testing
- Dexmedetomidine, Chloral Hydrate
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Seoul National University Childrens Hospital
Sacroiliac Joint Dysfunction
Modified Sims Versus Lumbar Roll Manipulation in Patients With Sacroiliac Joint Dysfunction
This randomized controlled trial aims to compare the efficacy of two manual therapy techniques. Modified Sims Manipulation and Lumbar Roll Manipulation in treating Sacroiliac Joint Dysfunction (SIJD).
- Trial name
- NCT07258537
- Testing
- modified SIM manipulation
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Lahore
Lateral Epicondylitis (Tennis Elbow)
Effectiveness of Extracorporeal Shockwave Therapy Based on Fascial Manipulation Theory for Lateral Epicondylitis
Goal: This clinical trial aims to find out if using fascial theory to guide shockwave therapy works better for treating "tennis elbow" (pain on the outer side of the elbow) compared to standard shockwave treatment.
- Trial name
- NCT07131423
- Testing
- Standard extracorporeal shock wave therapy, CC points shock wave therapy, Shock wave therapy for the CC points and the lateral epicondyle
- Where
- China
- Volunteers
- 123 people
- Sponsor
- ZHANG PENG
Cerebral Palsy
Effects of CHRIST Among Children With Spastic CP
This Quasi experimental study investigates the effects of CHRIST on In Hand Manipulation and Grip Strength amonfg children with Spastic Cerebral Palsy.
- Trial name
- NCT07244146
- Testing
- CHRIST
- Where
- Pakistan
- Volunteers
- 14 people
- Sponsor
- Riphah International University
Cerebral Palsy (CP)
Fascial Manipulation in Cerebral Palsy Rehabilitation
The purpose of the study is to investigate the potential additional benefits of a relatively new physiotherapy method, fascial manipulation, in the rehabilitation of movement difficulties or other problems caused by CP (cerebral…
- Trial name
- CP fascia (NCT06837025)
- Testing
- Fascial manipulation
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- Orton Orthopaedic Hospital
Cerebral Palsy (CP)
The Effect of Spinal Manipulation on Heart Rate Variability in Children With Cerebral Palsy.
This randomized, sham-controlled crossover trial aims to evaluate the immediate effects of spinal manipulation on heart rate variability in children with cerebral palsy.
- Trial name
- NCT07504640
- Testing
- Spinal manipulation
- Where
- Ukraine
- Volunteers
- 20 people
- Sponsor
- International Clinic of Rehabilitation, Ukraine
Developmental Coordination Disorder
Effects of Task-Oriented Intervention in Children With Developmental Coordination Disorder
physical coordination is impacted by developmental coordination disorder (DCD), commonly referred to as dyspraxia. It makes a youngster appear to move clumsily and perform worse than expected in everyday tasks for their age.
- Trial name
- NCT06736119
- Testing
- Task Oriented Intervention
- Where
- Pakistan
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Plagiocephaly, Nonsynostotic, Plagiocephaly, Positional
OPT-IN: Osteopathic Plagiocephaly Treatment for Infants and Neonates
The goal of this crossover randomized clinical trial is to assess the effects of osteopathic manipulative treatment (OMT) compared to standard of care repositioning in children diagnosed with positional/deformational…
- Conditions
- Plagiocephaly, Nonsynostotic, Plagiocephaly, Positional, Plagiocephaly, Cranium; Deformity
- Trial name
- OPT-IN (NCT05848895)
- Testing
- Osteopathic Manipulative Treatment, Standard of Care Repositioning
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- Osteopathy's Promise to Children
Parkinsons Disease, Sleep
Effects of Osteopathic Manipulative Treatment Protocol on Sleep Quality in Parkinson's Disease Subjects
Parkinsonism, mainly caused by Parkinsons disease (PD), includes symptoms like tremors, stiffness, slow movements, and balance problems.
- Trial name
- NCT06671600
- Testing
- Osteopathic Manipulative Treatment
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- New York Institute of Technology
Low Back Pain, Low Back Pain, Recurrent
Movement Control Exercises and Fascial Manipulation in Chronic Low Back Pain
Subjects are recruited from the attendees of the multidisciplinary low back pain rehabilitation group before it takes place in University Hospital of Oulu at Physical and Rehabilitation Medicine (PRM) unit.
- Trial name
- NCT03270631
- Testing
- FM and MCE
- Where
- Finland
- Volunteers
- 250 people
- Sponsor
- Oulu University Hospital
Malignant Hematologic Neoplasm
Fecal Microbiota Transplantation Among Adult Patients With Hematological Malignancies
In Hungary - in comparison to other member states of the European Union - about 75000 new cases of cancer are diagnosed annually, from which approximately 4500-5000 patients suffer from so-called malignant hematological diseases.
- Trial name
- HEMAT-FMT (NCT07172191)
- Testing
- Fecal Microbial Transplantation
- Where
- Hungary
- Volunteers
- 100 people
- Sponsor
- Del-Pest Central Hospital - National Institute of Hematology and Infectious Diseases