Clinical trials: Mass Screening
Diagnostics, Pandemic Response
High-throughput Serological Testing of Antibodies Platform
In the case of large emergency serosurveys, innovation in the sampling techniques is an often neglected, but relevant aspect to facilitate the enrolment of subjects in both adult and paediatric populations.
- Trial name
- DEVHISE (NCT06939556)
- Where
- 2 sites in Italy
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Istituto Zooprofilattico Sperimentale delle Venezie
Delirium
Nu-DESC DK: The Danish Version of the Nursing Delirium Screening Scale
Delirium is one of the most common complications among elderly hospitalized patients, postoperative patients and patients on intensive care units. The reported prevalence is between 11 and 80 %.
- Trial name
- Nu-DESC DK (NCT02628925)
- Testing
- Nu-DESC DK
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Naestved Hospital
Colorectal Cancer
Translation of Colorectal Cancer Screening Guidelines to Practice: A System Intervention
Colorectal cancer (CRC) is the second leading cause of cancer-related deaths in the United States. Results from randomized clinical trials and intervention studies have suggested that implementation of a CRC screening program for…
- Trial name
- NCT00122187
- Testing
- Electronic Consult System
- Where
- 9 sites in United States
- Volunteers
- 8 people
- Sponsor
- US Department of Veterans Affairs
Prostate Cancer Screening
Evaluation of An Online Intervention In Improving General Practitioners' Practice In Prostate Cancer Screening
The incidence of prostate cancer has been rising steadily both globally and in Malaysia. Besides an ageing population, another reason cited to explain the increase, is the corresponding increase in the prostate cancer screening…
- Trial name
- ProCaSS (NCT03633214)
- Testing
- Online training module
- Where
- Malaysia
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Pre-eclampsia, Pregnancy
IMproved PRegnancy Outcome by Early Detection
The overall objective of the IMPROvED project is to develop a sensitive, specific, high-throughput and economically viable early pregnancy screening test for preeclampsia.
- Conditions
- Pre-eclampsia, Pregnancy, Pregnancy, High-risk, Pregnancy Complications
- Trial name
- IMPROvED (NCT01891240)
- Where
- 6 sites in Ireland, Netherlands and 2 more
- Volunteers
- 5,000 people
- Sponsor
- Louise Kenny
Pompe Disease
Screening for Early Detection and Prevention of Pompe Disease in Israel Using Tandem Mass Spectrometry
The aim of the study is: to develop a comprehensive biochemical assay for detection of Pompe disease (glycogen storage disease type II), to be implemented in the Newborn screening program among the Israeli population.
- Trial name
- LC-MS-MS (NCT01409486)
- Testing
- Drawing blood spots from Newborns
- Where
- Israel
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Cervical Length, Preterm Birth
Development of a Screening Tool By Utilising Cervical Length Measurement In Relation To Body Mass Index (BMI) For Early Identification And Intervention Of Preterm Birth
This is a prospective study where pregnant women between 16-24 weeks gestation attending the Antenatal Clinic, Fetomaternal clinic or Obstetrics \& Gynaecology Admission Centre (OGAC) at Hospital Serdang or Hospital Pengajar UPM…
- Trial name
- NCT04922671
- Where
- 2 sites in Malaysia
- Volunteers
- 145 people
- Sponsor
- Universiti Putra Malaysia
Covid19, COVID-19 Pneumonia
imPulse™ Una Infrasound-to-ultrasound E-stethoscope
This study generates robust, uniform clinical data across emerging COVID-19 strains to train ML/AI algorithms of the Sponsor's imPulse™ Una infrasound-to-ultrasound e-stethoscope for digital diagnostic feature synthesis of…
- Conditions
- Covid19, COVID-19 Pneumonia, COVID-19 Respiratory Infection, COVID-19 Acute Respiratory Distress Syndrome
- Trial name
- NCT04941209
- Testing
- imPulse™ Una infrasound-to-ultrasound e-stethoscope, (PPA >95%) FDA EUA RT-PCR, HR-CT-scan
- Where
- 3 sites in Democratic Republic of the Congo, India and 1 more
- Volunteers
- 702 people
- Sponsor
- Level 42 AI, Inc.
Malaria
Surveillance and Treatment With Dihydroartemisinin-piperaquine Plus Primaquine
Mass Drug Administration (MDA) and Mass Screening and Selective Treatment (MST) might be applied as strategies for eliminating malaria when focusing on transmission stages.
- Trial name
- NCT01878357
- Testing
- dihydroartemisinin-piperaquine, primaquine
- Where
- Indonesia
- Volunteers
- 1,488 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Neonatal Screening, Lysosomal Storage Diseases
A Pilot Study for Systematic Neonatal Screening for Lysosomal Storage Diseases Using Tandem Mass Spectrometry
The study will include all newborns in Normandie region for 3 years (about 105,000 births) for whom signed consent by one (or two) parents will be collected.
- Trial name
- LysoNeo (NCT04393701)
- Testing
- Additional blood sampling
- Where
- 2 sites in France
- Volunteers
- 100,000 people
- Sponsor
- University Hospital, Rouen
Plasmodium Falciparum Malaria
Mass Screening and Treatment for Reduction of Falciparum Malaria
In this project, the investigators aim at an operational research deployment of Ultrasensitive Rapid Diagnostic Test (URDT) -based Mass Screening and Treatment (MSAT) in the Malaria Elimination Task Force (METF) elimination…
- Trial name
- MSAT (NCT04093765)
- Testing
- Ultrasensitive Rapid Diagnostic Test (URDT), Antimalarials
- Where
- Thailand
- Volunteers
- 5,542 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Suicidal Ideation, Social Behavior
Massive Mental Health Screening Using Smartphones in 24 Pre-graduate Education Centers in Mexico City: TEDUCA Survey Protocol
The objective of this study is to make a massive suicide risk and social behavior assessment in 24 pre-graduate education centers in Mexico City (approximately 30,000 students aged between 15 and 22 years), taking also into…
- Conditions
- Suicidal Ideation, Social Behavior, Depression, Depressive Disorder
- Trial name
- TEDUCA (NCT04067076)
- Testing
- Self-administered evaluation questionnaire
- Where
- Mexico
- Volunteers
- 30,000 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Colorectal Cancer
Use of Telehealth In-home Messaging to Improve GI (Gastrointestinal) Endoscopy Completion Rates
Low endoscopy completion rates are a major problem in the VA, causing delay or failure to receive essential care, increased clinic wait times, lost capacity, increased costs, thus limiting endoscopic screening for colorectal…
- Trial name
- GIVER (NCT00310362)
- Testing
- Use of Interactive Voice Response (IVR) system to improve adherence to GI appointments and prep procedures
- Where
- United States
- Volunteers
- 3,610 people
- Sponsor
- VA Office of Research and Development
Propionic/Methylmalonic Acidemias, Maple Syrup Urine Disease
Selective Screening of Children for Hereditary Metabolic Diseases by Tandem Mass Spectrometry in Kazakhstan
Inborn errors of metabolism (IEM) are not have specific clinical signs, they masquerade as other diseases, and are difficult to diagnose using only clinical manifestations or routine laboratory tests.
- Conditions
- Propionic/Methylmalonic Acidemias, Maple Syrup Urine Disease, Citrullinemia, Argininosuccinic Aciduria
- Trial name
- NCT05910151
- Testing
- Obtaining Dry Blood Spots From Healthy Newborns (Aged 1-7 Days), Obtaining Dry Blood Spots From Healthy Children Aged 8 Days - 7 Years, Obtaining Dry Blood Spots From Healthy Children Aged 8-18 Years
- Where
- Kazakhstan
- Volunteers
- 2,250 people, healthy volunteers welcome
- Sponsor
- West Kazakhstan Medical University
SARS-CoV Infection
Comparison of Strategies Based on RT-PCR or Antigenic Test for the Screening of SARS-CoV-2 Infection (COVID-19).
The virological diagnosis of SARS-CoV-2 infection is pivotal for the control of the outbreak by large screening of a- or pauci-symptomatic subjects.
- Trial name
- AutoCoV (NCT04859023)
- Testing
- saliva sample combined to an anterior nare self-swabbing (Self-samples), saliva sample (Self-sample), Survey of SARS-COV-19 knowledge
- Where
- France
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
PKU
Determining the Most Efficient Screening Cut Off Levels for Phenylketonuria (PKU)
studying the screening of PKU in france with the new tandemMS
- Trial name
- NCT06629987
- Where
- France
- Volunteers
- 360 people
- Sponsor
- Central Hospital, Nancy, France
Stillbirth, Intrauterine Growth Retardation
Antenatal Detection of Fetal Growth Restriction and Stillbirths Rate.
The main objective is to assess the role of antenatal detection of fetal growth restriction (FGR) on stillbirth, by a case-control study in a population-based sample of small for gestational age (SGA) livebirths and stillbirths…
- Conditions
- Stillbirth, Intrauterine Growth Retardation, Infant, Small for Gestational Age
- Trial name
- REPERE (NCT01995968)
- Testing
- Antenatal identification of fetal growth restriction
- Where
- 21 sites in France
- Volunteers
- 480 people
- Sponsor
- University Hospital, Grenoble
Suicidal Ideation, Depression
Population Screening Using Smartphone in Milpa Alta
The objective of this study is to make a suicide screening in the entire population of Milpa Alta (approximately 150,000 inhabitants), taking into account other outcomes such as depression, anxiety, alcohol and drugs.
- Conditions
- Suicidal Ideation, Depression, Depressive Disorder, Anxiety
- Trial name
- Smart-screen (NCT04067063)
- Testing
- Self-administered evaluation questionnaire
- Where
- Mexico
- Volunteers
- 150,000 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Inflammatory Bowel Diseases, Crohn Disease
Nutrition and Clinical Outcomes in IBD
The goal of this observational study is to demonstrate that nutritional status and body composition have an impact on clinical outcomes in inflammatory bowel disease (IBD). The main objectives are: 1.
- Conditions
- Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis, Malnutrition
- Trial name
- NUTRICO-IBD (NCT06550310)
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- Barts & The London NHS Trust
Mass Screening
Dengue Virus NS1 Antigen (Bio-Rad) Clinical Protocol
The purpose of the study is to screen blood donors for the presence of NS1 antigen of the dengue virus at the American Red Cross in Puerto Rico region (and Monroe County, Florida) using the Platelia Dengue NS1 Ag enzyme…
- Trial name
- NCT01226173
- Testing
- Bio-Rad Platelia Dengue NS1 Ag test
- Where
- 2 sites in United States, Puerto Rico
- Volunteers
- 182,353 people, healthy volunteers welcome
- Sponsor
- Bio-Rad Laboratories