Clinical trials: Maternal
Pregnant Adolescents
Kansas University Teen Mothers Project
Breastfeeding initiation and duration in adolescent mothers.
- Trial name
- NCT00222118
- Testing
- labor/birth preparation classes, intervention, usual care
- Where
- United States
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Covid19, Pregnancy Related
Safety, Testing/Transmission, and Outcomes in Pregnancies With COVID-19
Pregnant women are a vulnerable and high-risk population, as COVID-19 is associated with an increased risk preterm birth, cesarean section, and maternal critical care.
- Conditions
- Covid19, Pregnancy Related, Maternal Complication of Pregnancy, Coronavirus
- Trial name
- STOPCOVID19 (NCT04718220)
- Testing
- Antibody testing for SARS-CoV-2 IgG, Testing for SARS-CoV-2 RNA, Testing for SARS-CoV-2 IgM/IgG
- Where
- United States
- Volunteers
- 448 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Risk Assessment, Parenting
Randomized Controlled Trial of a Risk Reframing Tool to Change Mothers' Parenting Associated With Children's Risky Play
Children's risky play is associated with a variety of positive developmental, physical and mental health outcomes, including greater physical activity, self-confidence and risk management skills.
- Trial name
- NCT03374683
- Testing
- RR Digital Tool, RR In-Person Workshop, Position Statement on Active Outdoor Play
- Where
- Canada
- Volunteers
- 451 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Mental Health Disorder, Social Isolation
Peer Support Intervention to Mitigate Social Isolation and Stigma of Adolescent Motherhood in Zimbabwe
A community-based peer support intervention for adolescent mothers aged 14-18 years in Harare, Zimbabwe was developed and tested in partnership with adolescent mothers, community health workers, and key community stakeholders.
- Conditions
- Mental Health Disorder, Social Isolation, Stigma, Social
- Trial name
- NCT05213182
- Testing
- Young Women of Today
- Where
- United States
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- West Chester University of Pennsylvania
Mother-Child Relations, Preterm Birth
The 2015 Pelotas (Brazil) Birth Cohort Study
This is the fourth birth cohort to be carried out in the city of Pelotas (Brazil) including more than 4 thousand children followed-up since the pre-natal period to study maternal-child health.
- Conditions
- Mother-Child Relations, Preterm Birth, Infant Development, Breast Feeding
- Trial name
- NCT03271723
- Testing
- Observational study
- Where
- Brazil
- Volunteers
- 4,275 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Substance-Related Disorders, Alcohol-Related Disorders
Conflict Between Maternal Autonomy and Child Health in Substance-use
Qualitative project, comprising open-ended semi-structured interviews with healthcare workers, who provide antenatal care to substance-using women.
- Conditions
- Substance-Related Disorders, Alcohol-Related Disorders, Amphetamine-Related Disorders, Inhalant Abuse
- Trial name
- NCT02797990
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Maternal Morbidity
Obesity: Cesarean Health by Incision Placement
Hypothesis: A Pfannenstiel cesarean skin incision placed under the pannus (should a pannus exist) will have a higher maternal morbidity composite rate than a Cohen cesarean skin incision placed above the pannus (should a pannus…
- Trial name
- O-CHIP (NCT02909582)
- Testing
- Cohen Incision
- Where
- United States
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Contraceptive Usage
Increase First-time Mothers' Use of Postpartum Family Planning in Tanzania: The Connect Project
While a growing body of programs have shown promise to increase use of contraception among first time mothers (FTMs), difficulties remain in scaling beyond small pilot areas and institutionalizing within existing systems.
- Trial name
- Connect TZ (NCT06261970)
- Testing
- Connect
- Where
- 2 sites in Tanzania
- Volunteers
- 1,134 people, healthy volunteers welcome
- Sponsor
- George Washington University
Maternal Dietary Diversity, Iron-Folic Acid Supplementation
Assessing the Feasibility of Integrating a Package of Maternal Nutrition Interventions Into Antenatal Care Services in Burkina Faso
Alive \& Thrive (A\&T) is an initiative that supports the scaling up of nutrition interventions to save lives, prevent illnesses, and contribute to healthy growth and development through improved maternal nutrition, breastfeeding…
- Conditions
- Maternal Dietary Diversity, Iron-Folic Acid Supplementation, Early Initiation of Breastfeeding
- Trial name
- NCT04155437
- Testing
- Health Facility Level Interventions, Community Level Interventions, Health System Level Interventions
- Where
- United States
- Volunteers
- 8,110 people, healthy volunteers welcome
- Sponsor
- International Food Policy Research Institute
Pre-Eclampsia
Indonesia Pravastatin to Prevent Preeclampsia Study
BACKGROUND Preeclampsia is a major cause of maternal and neonatal morbidity worldwide. There is currently no cure for preeclampsia, the only definitive treatment is termination of pregnancy by induction of labour or caesarean…
- Trial name
- INOVASIA (NCT03648970)
- Testing
- Pravastatin
- Where
- 7 sites in Indonesia
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Universitas Airlangga
Cardiovascular Diseases, Diabetes Mellitus, Type 2
Healthy Lifestyle Promotion Program in Communities From the Yaqui Valley
The aim is to evaluate the change in indicators of lifestyle and its effect on cardiometabolic biomarkers as a response to an integrative mother-child intervention to promote healthy lifestyles and prevent food insecurity and…
- Trial name
- NUTRIGANDO (NCT05945862)
- Testing
- NUTRIGANDO
- Where
- Mexico
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Instituto Tecnologico de Sonora
Dental Caries
Study on Use of Xylitol-wipes to Prevent Dental Caries
Mutans streptococci (MS) and lactobacillus species (LB) are the two groups of infectious cariogenic (caries-causing) bacteria most strongly associated with dental caries (dental decay).
- Trial name
- WIPE (NCT01468727)
- Testing
- xylitol wipe
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cesarean Delivery Affecting Fetus or Newborn
Routine Maternal Leg Movements During the Second Stage and the Rate of Operative Deliveries
Cesarean delivery rates have risen in the US in a dramatic fashion from less than 5% in the 1960 to 32.7% by 2013 with stable rate around 32-33% in the last five years , cesarean delivery is associated with increased maternal…
- Trial name
- NCT03510130
- Testing
- Routine leg movement
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Preterm Birth, Injuries
Nurse-Family Partnership Impact Evaluation in South Carolina
This study evaluates the effects of the Nurse Family Partnership (NFP), an established home-visiting program, using a scientifically rigorous individual-level randomized controlled trial.
- Conditions
- Preterm Birth, Injuries, Maternal Behavior
- Trial name
- NFP (NCT03360539)
- Testing
- Nurse-Family Partnership
- Where
- 9 sites in United States
- Volunteers
- 5,670 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Child Development, Parenting
Impact of the Korea Early Childhood Home-visiting Intervention
Maternal and early childhood home visits have been proposed as an effective strategy to improve the health and development of disadvantaged children.
- Conditions
- Child Development, Parenting, Infant Development, Pregnancy Related
- Trial name
- KECHI (NCT04749888)
- Testing
- Targeted nurse-led home visiting
- Where
- 2 sites in South Korea
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Maternal Cardiometabolic Health, Infertility
St Mary's Assisted Reproductive Technology and Cardiometabolic Health: Modifiable Targets for Multimorbidity Prevention (START-HEALThY)
The main causes of death in women are conditions affecting the heart and blood vessels (cardiovascular disease, CVD). Women who have difficulties getting pregnant (infertility) may be at increased risk, but the reasons for this…
- Conditions
- Maternal Cardiometabolic Health, Infertility, Assisted Reproductive Technology, Cardiovascular Health
- Trial name
- START-HEALThY (NCT07173569)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Cesarean Delivery, Feeding Patterns
Postoperative Results of Early Versus On-demand Maternal Feeding After Cesarean Delivery
To compare early versus on demand maternal feeding after cesarean delivery regarding gastrointestinal complaints and patient's satisfaction.
- Conditions
- Cesarean Delivery, Feeding Patterns, Patient Satisfaction, Postoperative Nausea and Vomiting
- Trial name
- NCT03349151
- Testing
- Early feeding, On- Demand feeding
- Where
- Turkey (Türkiye)
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Pregnancy Related
Chamas for Change Validation
This team has shown that chamas can be tailored to increase the uptake of health services in pregnancy and infancy, sustain themselves beyond the period of funding and become integrated within a county's health strategy.
- Trial name
- NCT03187873
- Testing
- Chama cha MamaToto
- Where
- Kenya
- Volunteers
- 3,040 people, healthy volunteers welcome
- Sponsor
- Moi University
Maternal Health
Mobile Health Intervention (Support-moms) in Antenatal Care to Improve Maternal Health in Uganda
High maternal mortality is a major public health problem in many settings. Because of low antenatal care (ANC) and skilled birth usage, Ugandan women and their children suffer from high maternal and perinatal mortality.
- Trial name
- Support-Moms (NCT05940831)
- Testing
- Support-Moms, Control
- Where
- 2 sites in Uganda
- Volunteers
- 1,680 people, healthy volunteers welcome
- Sponsor
- Mbarara University of Science and Technology
Postpartum Period
W-PPMA for Postpartum Mothers
To evaluate the feasibility and acceptability of W-PPMA among a diverse group of postpartum mothers.
- Trial name
- NCT05662605
- Testing
- W-PPMA
- Where
- United States
- Volunteers
- 281 people, healthy volunteers welcome
- Sponsor
- Woebot Health