Clinical trials: Maternal-fetal Relations
Covid19, Pregnancy Related
Safety, Testing/Transmission, and Outcomes in Pregnancies With COVID-19
Pregnant women are a vulnerable and high-risk population, as COVID-19 is associated with an increased risk preterm birth, cesarean section, and maternal critical care.
- Conditions
- Covid19, Pregnancy Related, Maternal Complication of Pregnancy, Coronavirus
- Trial name
- STOPCOVID19 (NCT04718220)
- Testing
- Antibody testing for SARS-CoV-2 IgG, Testing for SARS-CoV-2 RNA, Testing for SARS-CoV-2 IgM/IgG
- Where
- United States
- Volunteers
- 448 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Child Development, Parenting
Impact of the Korea Early Childhood Home-visiting Intervention
Maternal and early childhood home visits have been proposed as an effective strategy to improve the health and development of disadvantaged children.
- Conditions
- Child Development, Parenting, Infant Development, Pregnancy Related
- Trial name
- KECHI (NCT04749888)
- Testing
- Targeted nurse-led home visiting
- Where
- 2 sites in South Korea
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Immunization; Infection, Pregnancy Related
VAX-MOM COVID-19: Increasing Maternal COVID-19 Vaccination
COVID-19 infection during pregnancy is associated with increased risk of pre-eclampsia, preterm birth and stillbirth. Pregnant people with COVID-19 have a higher rate of ICU admission and intubation than those who are not…
- Conditions
- Immunization; Infection, Pregnancy Related, COVID-19
- Trial name
- NCT05570630
- Testing
- VAX-MOM COVID-19 Intervention, Standard of Care
- Where
- United States
- Volunteers
- 6,911 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Congenital Heart Disease in Children, Hypoxia
Fetal Cerebrovascular Autoregulation in Congenital Heart Disease and Association With Neonatal Neurobehavior
Determine 1) the impact of abnormal fetal cerebrovascular physiology with neurodevelopmental delay (ND) outcomes and 2) how this relationship is modified by patient and environmental factors such as chronic congenital heart…
- Conditions
- Congenital Heart Disease in Children, Hypoxia, Neurodevelopmental Disorders, Complex Congenital Heart Disease
- Trial name
- NCT05767385
- Testing
- Single Arm, Neonatal Neurobehavioral Scale
- Where
- 5 sites in United States
- Volunteers
- 104 people
- Sponsor
- University of Utah
Pregnancy Related, Mindfulness
Effect of Mindfulness Education in Primiparous Pregnant Women
While adaptation is generally achieved to the psychological changes that develop during pregnancy, some women may experience psychological changes such as contradiction, uncertainty, introversion, passive personality, addiction…
- Conditions
- Pregnancy Related, Mindfulness, Fear of Childbirth, Attitude
- Trial name
- NCT05250479
- Testing
- Mindfulness education
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Ordu University
Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Infant Development
Maternal Adversity, Vulnerability and Neurodevelopment
Maternal Adversity Vulnerability and Neurodevelopment (MAVAN) project is a prospective community-based, pregnancy and birth cohort of Canadian mother-child dyads.
- Conditions
- Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Infant Development, Infant Behavior
- Trial name
- MAVAN (NCT03434457)
- Where
- Canada
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- Douglas Mental Health University Institute
Postpartum Depression, Posttraumatic Stress Disorder
Intervention for IPV-exposed Pregnant Women
The overarching goal of the proposed project is to evaluate a randomized clinical trial of the Pregnant Moms' Empowerment Program aimed at detecting its effects on maternal mental health, re-victimization, parenting sensitivity…
- Conditions
- Postpartum Depression, Posttraumatic Stress Disorder, Infant Behavior, Violence
- Trial name
- NCT04068662
- Testing
- Pregnant Moms' Empowerment Program, Nondirective Support Group
- Where
- 2 sites in United States
- Volunteers
- 424 people
- Sponsor
- University of Notre Dame
Maternal-Fetal Relations
Determinants of Fetal Inflammatory Exposure at Term
The hypothesis of this study is that maternal and fetal biologic variation in the balance between pro-inflammatory and anti-inflammatory mediators can be measured by currently available techniques.
- Trial name
- NCT00970151
- Where
- United States
- Volunteers
- 618 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Pregnancy, Cancer, Cancer in Pregnancy, Gestational Breast Cancer, Pregnancy Related
Maternal Cancer Diagnosis and Treatment During Pregnancy:a Database for Maternal, Fetal, and Neonatal Outcomes
The objective of this study is to follow the treatment options offered to pregnant women diagnosed with cancer and study the impact that their treatment or delay of treatment has on their own health and that of their children.
- Trial name
- CANCRPREGREG (NCT02749474)
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Cooper Norcross Health
Pregnancy Related
Elafibranor Pregnancy Surveillance Program: A Study to Evaluate the Safety of Elafibranor During Pregnancy
The study will include participants who were exposed to at least one dose of elafibranor either within the three weeks before conception or at any time during pregnancy (based on estimated last menstrual period [LMP]).
- Trial name
- NCT07556913
- Testing
- Elafibranor
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Ipsen
Pregnancy Related
Odevixibat Pregnancy and Lactation Surveillance Program: A Study to Evaluate the Safety of Odevixibat During Pregnancy and/or Lactation
The participants of this study will be of any age who are exposed to at least 1 dose of odevixibat at any time during pregnancy (from 1 day prior to conception to pregnancy outcome) and/or at any time during lactation (up to 12…
- Trial name
- NCT06258902
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Ipsen
Prenatal Depression, Mental Health Related Quality of Life
Technology Supported Mindfulness for Prenatal Depression and Mental Health-related Quality of Life in a Resource-Limited Environment
The goal of this clinical trial is to learn if a video-guided mindfulness intervention can improve prenatal depression symptoms, improve mental health-related quality of life, reduce the risk of maternal postpartum depression and…
- Conditions
- Prenatal Depression, Mental Health Related Quality of Life, Maternal Postpartum Depression, Paternal Postpartum Depression
- Trial name
- NCT07151781
- Testing
- Video-guided Mindfulness Exercise
- Where
- Ethiopia
- Volunteers
- 120 people
- Sponsor
- Bekelu Teka Worku
Maternal Care Patterns, Nutrition, Healthy
The 1000 First Day of Life : Effect of Multi Micronutrients Supplementation on Pregnancy Outcomes
To monitor the effects of multi micronutrients supplementations during pregnancy towards pregnancy outcomes
- Conditions
- Maternal Care Patterns, Nutrition, Healthy, Nutritional Deficiency, Maternal-Fetal Relations
- Trial name
- NCT06035315
- Testing
- Multiple Micronutrients during pregnancy
- Where
- 2 sites in Indonesia
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Dr Cipto Mangunkusumo General Hospital
Pregnancy Early, Pregnancy Related
Thyroid Stimulating Hormone (TSH) Level Variations in Early Pregnancy
Retrospective comparative study comparing group 1 (TSH level 0.1-1.99 mIU/L) and group 2 (TSH level 2.0-4 mIU/L). Each group was further subdivided into primigravidae and multipara. 1527 pregnant women were included.
- Conditions
- Pregnancy Early, Pregnancy Related, Thyroid Dysfunction
- Trial name
- NCT04565873
- Testing
- TSH
- Where
- Jordan
- Volunteers
- 1,527 people
- Sponsor
- University of Jordan
Maternal-Fetal Relations, Depression
Familiy Medicine Perspective to Maternal-infant Bonding
Maternal bonding was described as a qualitative change in the relationship of a mother with her infant. By this study, the investigators aimed to investigate the mother-infant bonding and the factors affecting it, from the point…
- Conditions
- Maternal-Fetal Relations, Depression, Anxiety
- Trial name
- NCT03357965
- Testing
- Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 73 people
- Sponsor
- Yildiz Atadag
Preterm Birth
Maternal Anxiety Related to How the Pediatrician Provided Prenatal Information About Preterm Birth
Women hospitalized for preterm labor require clear information about prematurity. This study assessed whether or not specific written information about prematurity delivered at admission to the unit combined with an oral…
- Trial name
- Infoprema (NCT03646578)
- Testing
- State of anxiety
- Where
- France
- Volunteers
- 65 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Fetal Macrosomia, Obesity Complicating Childbirth
Investigating the Relationship Between Triglycerides and Fetal Overgrowth in Gestational Diabetes
This is a prospective, observational study which examines the association between maternal triglycerides in the antepartum period and fetal overgrowth in pregnancies complicated by gestational diabetes.
- Conditions
- Fetal Macrosomia, Obesity Complicating Childbirth, Gestational Diabetes
- Trial name
- NCT06067685
- Testing
- Observation
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
HIV Infections, Pregnancy
A Phase III Randomized, Double-Blind, Controlled Study of the Use of Anti-HIV Immune Serum Globulin (HIVIG) for the Prevention of Maternal-Fetal HIV Transmission in Pregnant Women and Newborns Receiving Zidovudine (AZT)
To evaluate the effect of anti-HIV immune serum globulin (HIVIG) versus immune globulin (IVIG) administered during pregnancy and to the newborn, in combination with zidovudine (AZT) administered intrapartum and to the newborn, on…
- Trial name
- NCT00000751
- Testing
- Anti-HIV Immune Serum Globulin (Human), Globulin, Immune, Zidovudine
- Where
- 51 sites in United States, Puerto Rico
- Volunteers
- 1,600 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Maternal-Fetal Relations
The Efficacy of Maternal Sound for Pediatric Patients Undergoing Cardiac Surgery
A newborn's recognition and preference for their mother's voice occurs early in life, very likely during fetal development. Maternal voice stimuli undergo a unique form of cerebral processing that lends support for the existence…
- Trial name
- NCT02674126
- Testing
- Control group, Maternal sound group
- Where
- Egypt
- Volunteers
- 106 people
- Sponsor
- Assiut University
Cocaine, Substance Abuse
The Maternal Lifestyle Study (MLS)
This is a longitudinal, multi-site observational study of the long-term effects of a mother's use of cocaine and/or opiates during pregnancy on her infant.
- Conditions
- Cocaine, Substance Abuse, Infant, Newborn, Pregnancy
- Trial name
- MLS (NCT00059540)
- Where
- 5 sites in United States
- Volunteers
- 11,811 people, healthy volunteers welcome
- Sponsor
- NICHD Neonatal Research Network