Clinical trials: Medical Abortion
Induced Abortion
Comparison of Two Regimens of Misoprostol for Second Trimester Medical Termination of Pregnancy
The hypothesis of the study is that the induction abortion interval time will be significantly shorter in the group receiving vaginal misoprostol every six hours in comparison to the group who are receiving vaginal misoprostol…
- Trial name
- NCT00401440
- Testing
- Misoprostol
- Where
- India
- Volunteers
- 185 people
- Sponsor
- Nilratan Sircar Medical College
Medical Abortion, Complete or Unspecified, Without Complication
Piloting Use of Multi-Level Pregnancy Tests in Remote Abortion Services
Serial use of urine multi-level pregnancy tests (MLPTs) has been shown to be a reliable and efficient strategy for excluding ongoing pregnancy after medical abortion at ≤ 63 days of gestation.
- Trial name
- NCT03207880
- Testing
- Multi-level pregnancy test
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Pregnancy, Violence Against Women (VAW)
Requests for Voluntary Termination and Medical Termination of Pregnancy for Maternal, Psychological or Social Reasons At the Women's Center ( La Maison Des Femmes) in Saint-Denis :
In France, Article L2213-1 of the Public Health Code (law of July 4, 2001) clearly establishes that "voluntary termination of pregnancy may be performed at any time if two doctors, who are part of a multidisciplinary team…
- Conditions
- Pregnancy, Violence Against Women (VAW), Violence, Abortion
- Trial name
- NCT06708208
- Where
- France
- Volunteers
- 107 people
- Sponsor
- Centre Hospitalier de Saint-Denis
Pregnancy Related
Telemedicine Medical Abortion Service Using the "No-test" Protocol in Azerbaijan.
The goal of this study is to pilot and evaluate a telemedicine medical abortion service delivery that allows remote communication between the woman and provider and limits medically unnecessary in-person visits to health or…
- Trial name
- NCT05459142
- Testing
- Medical Abortion
- Where
- Azerbaijan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Induced Abortion, Second Trimester Abortion
Midlevel Versus Physician-provided Medical Abortion in the Second Trimester
The purpose of the study is to determine the safety and effectiveness of second trimester medical abortion when provided by nurse midwives compared with physicians.
- Conditions
- Induced Abortion, Second Trimester Abortion, Medical Abortion, Health Personnel
- Trial name
- NCT04181541
- Testing
- Provider type: Physicians, Provider type: Midlevel Providers
- Where
- Ethiopia
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- Ipas
Early Pregnancy Failure
Comparing Two Medical Treatments for Early Pregnancy Failure.
This study aims to compare whether a combination of two drugs (Mifepristone and misoprostol) are superior compared to using only one of these drugs (Misoprostol) as medical treatment for a miscarriage.
- Trial name
- Triple M (NCT03212352)
- Testing
- Mifepristone, Misoprostol
- Where
- 13 sites in Netherlands
- Volunteers
- 342 people
- Sponsor
- Radboud University Medical Center
Pregnancy
Telemedicine Medical Abortion Service Using the "No-test" Protocol in Ukraine and Uzbekistan.
The goal of this study is to pilot and evaluate a telemedicine medical abortion service delivery that allows remote communication between the woman and provider and limits medically unnecessary in-person visits to health or…
- Trial name
- NCT05028387
- Testing
- medical abortion
- Where
- 4 sites in Ukraine, Uzbekistan
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Medical Abortion
Effectiveness of Pregnancy Tests as an Assessment Tool to Identify Continuing Pregnancy
This randomized study will examine the effectiveness of two types of pregnancy tests (a semi-quantitative test and a high sensitivity test) to identify continuing pregnancy at home at various time points after early medical…
- Trial name
- NCT01856777
- Testing
- Semi-quantitative panel test, High sensitivity urine pregnancy test
- Where
- 2 sites in Vietnam
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Medical Abortion
Mifepristone and Two Doses of Misoprostol for Abortion at 11&12 Weeks
This study seeks to evaluate the efficacy, side effect profile and acceptability of a medical abortion regimen with mifepristone and two doses of 800 mcg misoprostol buccally at 71-77 and 78-84 days of gestation to further expand…
- Trial name
- NCT05119439
- Testing
- Mifepristone + 2 doses of misoprostol 800 mcg
- Where
- 6 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Medical Abortion
The Acceptability and Feasibility of an Alternative to Routine Follow-up Visit After Medical Abortion in Vietnam
This trial will compare the efficacy and acceptability of post-medical abortion follow-up by assigning women to either 1) alternative follow-up via routine semi-quantitative pregnancy test and a self-administered follow-up…
- Trial name
- NCT01150422
- Testing
- Alternative follow-up
- Where
- 4 sites in Vietnam
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Induced Abortion, Medical Abortion
Assessment of Pain During an Abortion With Knowledge of the Predictive Factors of Pain.
Two studies carried out in 2011 at the Center for Contraception and Voluntary Interruption of Pregnancy (CIVG) at the Louis-Mourier Hospital, evaluated the pain of patients undergoing an abortion, and looked for predictors of the…
- Conditions
- Induced Abortion, Medical Abortion, Surgical Abortion, Pain
- Trial name
- NCT05532085
- Testing
- Evaluation of pain during voluntary termination of pregnancy with medication following consideration of predictive factors of pain without an established analgesic protocol, Evaluation of pain during a voluntary medical termination of pregnancy following consideration of predictive factors of pain with an established analgesic protocol, Assessment of pain during voluntary termination of pregnancy by aspiration under local anesthesia following consideration of predictive factors of pain without an established analgesic protocol
- Where
- France
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- Olivier CHASSANY
Abortion Early
Point of Care Tests in the Management of Very Early Medical Abortion
This study will investigate the use of a point of care test in patients who are having an abortion at a gestation of <6 weeks (known as a very early medical abortion).
- Trial name
- POCT VEMA (NCT07417787)
- Testing
- Blood test, Participant Questionnaire
- Where
- 3 sites in Sweden, United Kingdom
- Volunteers
- 130 people
- Sponsor
- University of Edinburgh
Abortion, Induced
Mifepristone Plus Misoprostol Versus Misoprostol Alone for 2nd Trimester Abortion (14 - 21 Weeks Last Menstrual Period (LMP))
The primary goal of this study is to determine the clinical advantage of pre-treatment with mifepristone in second trimester misoprostol induction abortion.
- Trial name
- NCT00969982
- Testing
- mifepristone+misoprostol
- Where
- 2 sites in Moldova, Tunisia
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Medical Abortion
Simplifying Menstrual Regulation (MR): Post Abortion Care in Pakistan
This study is an additional component of protocol 6005, titled Simplifying Menstrual Regulation (MR): Exploring the role of at-home semi-quantitative pregnancy tests for follow-up to menstrual regulation service provision in…
- Trial name
- NCT02343913
- Testing
- PAC checklist
- Where
- 15 sites in Pakistan
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Induced Abortion, First Trimester Abortion
Study of Clinic-based Versus Self-use of Medical Abortion Pills
The goal of the study is to determine whether important clinical outcomes differ among women who access a combined medical abortion regimen from a pharmacy when compared with those who access it from a facility.
- Conditions
- Induced Abortion, First Trimester Abortion, Misoprostol, Mifepristone
- Trial name
- MOC (NCT03727308)
- Testing
- Medical abortion pills sourced from pharmacies, Medical abortion pills sourced from health clinics
- Where
- 2 sites in Cambodia, Ghana
- Volunteers
- 4,196 people, healthy volunteers welcome
- Sponsor
- Ipas
Medical; Abortion, Fetus
Mifepristone and Misoprostol for the Termination of Pregnancy up to 70 Days Gestation
The purpose of this study is to determine the efficacy and acceptability of a regimen of 200 mg mifepristone (Zacafemyl), followed 24-48 hours later by 800 mcg of buccal misoprostol.
- Trial name
- NCT01966874
- Where
- United States
- Volunteers
- 1,001 people
- Sponsor
- Gynuity Health Projects
Pregnancy
Effectiveness of Two Regimens of Misoprostol Alone for Early Pregnancy Termination and Use of SQPT for At-Home Follow-Up
This randomized trial will compare the rates of ongoing pregnancy, safety/side effects and acceptability of two medical abortion regimens that are commonly used in Latin America.
- Trial name
- NCT02299401
- Testing
- Misoprostol, Semi-quantitative pregnancy test
- Where
- 2 sites in Bolivia, Ecuador
- Volunteers
- 401 people
- Sponsor
- Gynuity Health Projects
Termination of Pregnancy Second Trimester
Misoprostol for Second Trimester Termination of Pregnancy
To compare the efficacy of two different dose regimens of misoprostol administered vaginally in combination with mifepristone in second trimester termination of (non)viable pregnancy.
- Trial name
- MIMIS (NCT00945997)
- Testing
- misoprostol
- Where
- Netherlands
- Volunteers
- 176 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Unwanted Pregnancies
Comparing Methotrexate Followed by Misoprostol to Misoprostol Alone for Early Abortion
Background: In most countries in which abortion is legal, medical abortions are induced with mifepristone and misoprostol. Since mifepristone is expensive and unavailable in many countries, it is important to find other regimens.
- Trial name
- NCT00129506
- Testing
- methotrexate + misoprostol, misoprostol
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- Wiebe, Ellen, M.D.
Medical Abortion
De-Medicalizing Mifepristone Medical Abortion
This study will investigate the possibility that medical abortion using mifepristone and misoprostol - a safe, proven therapy for terminating early first trimester pregnancy - can be administered in a manner that is simpler and…
- Trial name
- NCT00120224
- Where
- 3 sites in United States
- Volunteers
- 4,410 people
- Sponsor
- Gynuity Health Projects