Clinical trials: Medication Abuse
Substance Use, Delinquency
Family-based and Adolescent Residential Drug Treatment
The fundamental objective of this study is to compare the effectiveness of an intensive in-home family-based treatment, Multidimensional Family Therapy, with a multifaceted residential treatment, Adolescent Residential Treatment…
- Trial name
- ART (NCT01737632)
- Testing
- Multidimensional Family Therapy (MDFT), Adolescent Residential Treatment
- Where
- 2 sites in United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University of Miami
Prescription Drug Abuse (Not Dependent), Intentional Misuse
Preventing Prescription Stimulant Diversion and Medication Misuse Via a Web-Based Simulation Intervention
Half or nearly half of college students with prescriptions divert their stimulant medication, and a similarly high percentage misuse their medication or use someone else's prescription.
- Trial name
- NCT04885166
- Testing
- Web-based simulation active intervention
- Where
- 3 sites in United States
- Volunteers
- 249 people
- Sponsor
- Trinity College
Alcohol Abuse, Alcohol Dependence
Development and Testing of Adolescent Twelve-Step Facilitation
This study is the first to develop and test in a randomized experimental design the efficacy of an integrated 12-step facilitation intervention tailored for young people.
- Conditions
- Alcohol Abuse, Alcohol Dependence, Drug Abuse, Drug Dependence
- Trial name
- NCT01449981
- Testing
- Integrated Twelve-Step Facilitation, Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Massachusetts General Hospital
Substance Use Disorder (SUD), Drug Abuse
Adapted RPM-08 for Substance Use Disorder in Pakistan
The goal of this clinical trial is to learn if a culturally adapted Relapse Prevention Module (RPM-08) can reduce relapse risk in people with substance use disorders in Pakistan.
- Conditions
- Substance Use Disorder (SUD), Drug Abuse, Relapse
- Trial name
- NCT07552623
- Testing
- Adapted Relapse Prevention Module (RPM-08), Treatment as Usual (TAU)
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Universiti Sains Malaysia
Tobacco Use Disorder, Alcohol Use Disorder
Family-Skills Training to Prevent Tobacco and Other Substance Use in Latino Youth
The goal of this project is to evaluate the effectiveness of a family-based tobacco use prevention intervention directed at immigrant Latino parents of middle school aged youth as delivered in partnership with seven community…
- Conditions
- Tobacco Use Disorder, Alcohol Use Disorder, Drug Use Disorder, Smoking
- Trial name
- NCT01442753
- Testing
- Family-Skills Training
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Adolescent Substance Use
Differential Sensitivity Markers in Youth Drug Abuse Prevention
This pilot study conducts feasibility and exploratory intervention outcome research that will lead to the development of a personalized intervention framework that seeks to preempt the progression from early drug use to more…
- Trial name
- NCT02622451
- Testing
- Teen Intervene, Everyday Parenting
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Minnesota
Opioid-Related Disorders, Opiate Dependence
Treatment of Opioid Dependent Patients With Suboxone: Acceptability & Safety Data From Real Life Scenario (Study P05603)
The aim of this post marketing surveillance study is to investigate the retention rate after 12 months of drug dependence treatment with SUBOXONE® (buprenorphine plus naloxone) of opioid dependent patients under real life…
- Conditions
- Opioid-Related Disorders, Opiate Dependence, Drug Abuse
- Trial name
- NCT00723749
- Testing
- Buprenorphine/Naloxone
- Volunteers
- 384 people
- Sponsor
- Indivior Inc.
Attention Deficit Disorder With Hyperactivity, Conduct Disorder
Brain Indices of Stimulant Treatment in Drug-Naive Youth at Risk for Substance Use Disorder
Childhood ADHD and comorbid oppositional defiant disorder (ODD) and conduct disorder (CD) are considered risk factors for subsequent substance abuse, and youth with both ADHD and ODD/CD are at greatest risk.
- Conditions
- Attention Deficit Disorder With Hyperactivity, Conduct Disorder, Substance Abuse
- Trial name
- NCT04170738
- Testing
- Adderall
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Jeffrey Newcorn
Cannabis Dependence
A Trial of N-Acetylcysteine (an Over-the-Counter Medicine) in Adolescents Who Smoke Marijuana
This study is investigating how N-Acetylcysteine (NAC), an over-the-counter medication, will reduce marijuana use when combined with Contingency Management, a behavioral treatment.
- Trial name
- NCT01005810
- Testing
- N-Acetylcysteine, Contingency Management
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Medical University of South Carolina
Alcohol Abuse, Drug Abuse
Reducing Problematic Substance Use in Youth With Chronic Medical Conditions
The investigators goal is to pilot a substance use-related brief intervention (BI) for youth with chronic medical conditions, obtaining preliminary evidence of feasibility, acceptability and impacts of the approach for reducing…
- Trial name
- NCT01709201
- Testing
- Brief Intervention
- Where
- United States
- Sponsor
- Boston Children's Hospital
Prescription Drug Abuse (Not Dependent), Substance Use
Preventing Prescription Drug Abuse in Middle School Students
This project is designed to test a primary prevention approach to the problem of prescription drug misuse and abuse (PDA) among middle school students.
- Conditions
- Prescription Drug Abuse (Not Dependent), Substance Use, Substance Abuse
- Trial name
- MSPDA (NCT03129334)
- Testing
- LST Middle School Online
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- National Health Promotion Associates, Inc.
Drug Abuse, Alcohol Abuse
Trial of Computerized MET for Adolescent Substance Use
The purpose of this study is to test the effects of a computerized, self-directed Motivational Enhancement Therapy program for adolescent substance use (iMET), in comparison to clinician-delivered MET and Treatment As Usual…
- Conditions
- Drug Abuse, Alcohol Abuse, Nicotine Dependence
- Trial name
- NCT01784653
- Testing
- iMET, MET
- Where
- United States
- Sponsor
- Boston Children's Hospital
Medication Abuse, Harm Reduction
Clinical Decision Support for Safety of Opioid Transitions
The objective of this study is to evaluate the impact of a clinical decision support (CDS) alert designed to notify providers when an opioid prescription will result in a patient transitioning into a new phase of opioid therapy.
- Trial name
- NCT06527040
- Testing
- Opioid Transitions Clinical Decision Support (CDS)
- Where
- United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Substance Use, Unsafe Sexual Behavior
Familias Unidas: Preventing Drug Abuse and HIV in Hispanic First Offenders
The main goal of the proposed study is to evaluate the efficacy of Familias Unidas (United Families), a family-based, ecodevelopmental intervention found to be previously efficacious in preventing and reducing behavior problems…
- Trial name
- NCT01257022
- Testing
- Familias Unidas
- Where
- United States
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- University of Miami
Opiate Addiction
Comparison of Buprenorphine/Naloxone With Naltrexone in Opioid Dependent Adolescents
This study is designed to determine the relative effectiveness of buprenorphine/naloxone (Suboxone) pharmacotherapy versus naltrexone pharmacotherapy for treatment retention, relapse prevention and opioid craving reduction among…
- Trial name
- NCT01015066
- Testing
- Buprenorphine/naloxone, Naltrexone
- Where
- United States
- Sponsor
- State University of New York at Buffalo
Medication Abuse, Harm Reduction
Clinical Decision Support to Increase Use of Medications for Opioid Use Disorder
The objective of this study is to evaluate the impact of clinical decision support (CDS) in the form of an alert to identify patients who may be at risk of opioid use disorder (OUD) and a clinical care pathway helping providers…
- Conditions
- Medication Abuse, Harm Reduction, Opioid Use Disorder, Supportive Care
- Trial name
- NCT06526286
- Testing
- Medications for Opioid Use Disorder Pathway Clinical Decision Support (CDS)
- Where
- United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Divorce, Drug Abuse
Multi-court Trial of NBP to Prevent Substance Abuse and Mental Health Disorders (MTC)
This application requests funding to conduct a randomized effectiveness trial of The New Beginnings Program (NBP) delivered through a partnership of domestic relations courts, community service providers and the NBP research…
- Conditions
- Divorce, Drug Abuse, Mental Health Disorder
- Trial name
- MTC (NCT06132971)
- Testing
- New Beginnings Program
- Where
- United States
- Volunteers
- 2,415 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Substance Abuse Problem
Effect of Educational Program on Knowledge, Behavior and Involvement in Substance Abuse Among Adolescents
The aim of study was to effect of educational program by using behavior change wheel model on knowledge, behavior and involvement in substance abuse among adolescents.
- Trial name
- NCT07184164
- Testing
- Educational Program by Using Behavior Change Wheel Model, Routine Health Education
- Where
- Egypt
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Substance Use, Substance Abuse
Family Engagement, Cross-System Linkage to Substance Use Treatment for Juvenile Probationers -- Phase 3
Developed from adapting and combining two evidence-based programs, Project CONNECT (a linkage-to-services program that targets barriers within the probation and substance abuse treatment systems) and TIES (a program that teaches…
- Conditions
- Substance Use, Substance Abuse, Substance Use Disorders, Substance-Related Disorders
- Trial name
- NCT03048552
- Testing
- Family CONNECT
- Volunteers
- 22 people
- Sponsor
- New York State Psychiatric Institute
Substance Abuse, Risk Reduction
First Years Away From Home: Letting Go and Staying Connected
Alcohol abuse is the leading cause of death and serious injury among college students, and students also experience significant harms from other types of substance misuse and risk behaviors.
- Conditions
- Substance Abuse, Risk Reduction, RIsky Sexual Behavior
- Trial name
- FYAH:LGSC (NCT03227809)
- Testing
- Handbook condition, Handbook plus condition
- Where
- United States
- Volunteers
- 910 people, healthy volunteers welcome
- Sponsor
- Washington State University