Clinical trials: Memory
ADHD
Accelerated iTBS Targeting of Working Memory Versus Inhibitory Control in Adolescent ADHD
The objective of this project is to examine the differential therapeutic effect of intermittent theta burst stimulation (iTBS; a type of repetitive transcranial magnetic stimulation) to the left DLPFC versus right PreSMA in…
- Trial name
- WINK (NCT07219810)
- Testing
- intermittent theta burst stimulation (iTBS)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Bradley Hospital
Meningitis, Meningococcal
Study Evaluating the Tolerance of Conjugate Meningococcal C Vaccine in Infants
Infant phase: To determine the safety of and production of antibodies by a group C meningococcal conjugate vaccine (MnCC), when given at 2, 3, and 4 months of age with routine vaccines.
- Trial name
- NCT00314041
- Testing
- Meningococcal C, DTP/Hib
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
School Readiness, Executive Function (Cognition)
Playful Physical Activity for Executive Functions and School Readiness in Preschool Children
Executive functions, such as attention, inhibition, working memory, and planning, are important for early learning and school readiness in preschool children.
- Conditions
- School Readiness, Executive Function (Cognition), Preschool Child Development
- Trial name
- PPA-EF-SR (NCT07678294)
- Testing
- Playful Physical Activities Intervention, Regular Physical Education Curriculum
- Where
- Tunisia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Inonu University
Post-Traumatic Stress Disorders, Healthy
Effects of Hydrocortisone in Patients With Post-Traumatic Stress Disorder
The purpose of this study is to determine whether people who develop Post-Traumatic Stress Disorder (PTSD) after a trauma have increased sensitivity to the effects of a stress hormone.
- Trial name
- NCT00039715
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Lymphoma, Leukemia
Transfer of Effector Memory T Cells (Tem) Following Allogeneic Stem Cell Transplantation
RATIONALE: Following stem cell transplantation, a major risk is graft-versus-host disease (GVHD). This occurs when donor immune cells that have been infused recognise the host's cells as 'foreign' and attack these cells.
- Conditions
- Lymphoma, Leukemia, Myeloma, Myelodysplastic Syndromes
- Trial name
- ToTem (NCT03836690)
- Testing
- CD62L- Tem
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University College, London
Pediatric Obesity, Binge Eating
Project TEACH: The Eating, Affect, and Cognitive Health Study
Specific aims are to: 1. Assess variability in performance on state-level measures of working memory (WM) delivered via Ecological Momentary Assessment (EMA).
- Trial name
- NCT04121598
- Testing
- Observational
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Pittsburgh
Hepatitis B, Vaccine
Antibody Response and Immune Memory 15-18 Years After HBV Vaccination
Taiwan is an endemic region for hepatitis B. Before the implementation of a nationwide vaccination program in 1984, the hepatitis B virus (HBV) carrier rate in the general population was 15 to 20%.1-2 The major impact of…
- Trial name
- NCT00172328
- Testing
- Hepatitis B vaccine
- Where
- Taiwan
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Traumatic Brain Injury
Cogmed for Working Memory After TBI
This study will examine a cognitive rehabilitation protocol targeted at working memory deficits for adults and children with Traumatic Brain Injury (TBI).
- Trial name
- Cogmed (NCT02305212)
- Testing
- Cogmed
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Kessler Foundation
HPV Infection, HPV Vaccination
Effectiveness of the Q-HPV Vaccine 9-years Post Vaccination Among HIV Positive Adolescents
The risk for Human Papillomavirus (HPV) infection persists through an individual sexual life and duration of protection is critical to vaccine effectiveness in protection from oncogenic hrHPV infection.
- Trial name
- NCT05435209
- Testing
- Quadrivalent Human Papillomavirus (Types 6,11,16,18) Recombinant Vaccine
- Where
- Kenya
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- University of Washington
Traumatic Brain Injury
Prospective Memory in Children With Traumatic Brain Injury
Prospective memory (PM) is memory to complete future tasks, such as recalling to give a note to someone when you next see them, pick up milk on the way home, or remembering to keep an appointment.
- Trial name
- NCT00061399
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Adherence, Substance Abuse
Targeting PM to Improve HIV Adherence in Adolescents at Risk for Substance Abuse
Medication adherence rates among youth living with HIV are inadequate to effectively manage the disease, and novel interventions grounded in basic behavioral sciences are needed.
- Trial name
- NCT01959217
- Testing
- PM Component Text Reminders
- Where
- 2 sites in United States
- Volunteers
- 104 people
- Sponsor
- Wayne State University
Brain Tumor, Pediatric
Irradiation in Paediatrics: Neurocognition, Neuroimaging and Evaluation of Memory and Attention
This is a prospective, open-label, multicentric study designed to correlate the dose delivered to the hippocampus with declarative memory deficits 2 years after radiotherapy treatment in a paediatric population who had received…
- Trial name
- IPANEMA (NCT06599879)
- Testing
- Neuropsychological assessments:
- Where
- 14 sites in France
- Volunteers
- 130 people
- Sponsor
- Institut Claudius Regaud
Eosinophilia-Myalgia Syndrome
L-5-HTP-Related EMS
In 1989 more than 1500 people who took the dietary supplement L-tryptophan for insomnia and depression developed eosinophilia myalgia syndrome (EMS)-a potentially fatal disease characterized by an excess of a type of white blood…
- Trial name
- NCT00001918
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Institute of Mental Health (NIMH)
Neurodevelopmental Changes (Childhood, Ageing)
Understanding New Semantic Memory Learnings Across the Lifespan
The aim of this research is to specify the changes in brain connectivity (i.e. EEG phase synchronisation between brain regions) associated with semantic learning between individuals belonging to different age groups.
- Trial name
- ULIS (NCT06442670)
- Testing
- Electroencephalography
- Volunteers
- 200 people
- Sponsor
- University Hospital, Caen
Sleep Duration, Child Obesity
Effect of Sleep Extension on Body Weight and Learning in Children (More2Sleep)
More2Sleep is a randomized, controlled, parallel trial with two groups (sleep extension vs control) including 142 school-aged children (6-12 years) who have a BMI above average, defined as age- and sex-specific BMI Z-score above…
- Conditions
- Sleep Duration, Child Obesity, Child Development, Child Behavior
- Trial name
- More2Sleep (NCT06341179)
- Testing
- Sleep extension
- Where
- 3 sites in Denmark
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Central Auditory Processing Disorder
Virtual Reality Game to Enhance Auditory Processing in Children With Cochlear Implants
This study aimed to design and evaluate the effectiveness of a virtual reality-based restaurant simulation game to improve central auditory processing skills in children with bilateral cochlear implants.
- Trial name
- NCT06788184
- Testing
- Virtual Reality (VR) Game for Auditory Processing, Traditional Auditory Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Istanbul Aydın University
Healthy
Explore the Nature Factors Relevant to Learning-Pioneering Natural Factors That Influences Science Learning II
Genetic research has provided the most exciting breakthroughs in neuroscience and cognitive science. Partially genetically determined cognitive impairments have been described in people with COMT, 5HT6, BDNF (Swillen et al.…
- Trial name
- NCT00713570
- Where
- Taiwan
- Volunteers
- 2,800 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Sickle Cell Disease
Working Memory and School Readiness in Preschool-Aged Children With Sickle Cell Disease
Children with sickle cell disease (SCD) are at risk for neurobehavioral problems because of the impact the disease can have on the central nervous system.
- Trial name
- NCT02227472
- Testing
- Evaluation of cognitive and pre-academic skills, Parent questionnaires
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- St. Jude Children's Research Hospital
Alzheimer Disease, Dementia
A Survey Study of the Treatment and Outcome Management in Patients Diagnosed With Alzheimer's Disease
The purpose of this study is to collect and compare information regarding the treatment and outcome of patients diagnosed with Alzheimer's disease who are receiving either drug or nondrug treatment.
- Conditions
- Alzheimer Disease, Dementia, Nervous System Diseases, Mental Disorders
- Trial name
- NCT00291421
- Volunteers
- 2,360 people
- Sponsor
- Janssen Pharmaceutica N.V., Belgium
Primary Progressive Aphasia, Semantic Dementia
Primary Progressive Aphasia Multicomponent Language Treatment Study
The goal of this clinical trial is to learn if a speech-language telerehabilitation helps improve communication in people with primary progressive aphasia (PPA), a form of dementia that affects speech and language.
- Conditions
- Primary Progressive Aphasia, Semantic Dementia, Semantic Memory Disorder, Logopenic Progressive Aphasia
- Trial name
- NCT06649084
- Testing
- Multicomponent Lexical Retrieval Training (Multi-LRT), Multicomponent Video Implemented Script Training in Aphasia (Multi-VISTA), Multicomponent Communication Partner Training (Multi-CPT)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Texas at Austin