Clinical trials: Menstrual Flow Excessive
Heavy Menstrual Bleeding, Bleeding Disorder
Heavy Menstrual Bleeding Progestin Treatment in Bleeding Disorders Study
The goal of this multicenter prospective observational study and registry of U.S. adolescents and young adults with heritable bleeding disorders is to determine the bleeding outcomes, satisfaction, hemostatic parameter changes…
- Conditions
- Heavy Menstrual Bleeding, Bleeding Disorder, Von Willebrand Diseases
- Trial name
- HMB-BD (NCT05916469)
- Testing
- Levonorgestrel Intrauterine System, Norethindrone Acetate
- Where
- 9 sites in United States
- Volunteers
- 300 people
- Sponsor
- Oregon Health and Science University
Heavy Menstrual Bleeding
Tranexamic Acid in Adolescents With Heavy Menstrual Bleeding
This is a study to learn more about a drug called Tranexamic acid (TA), otherwise known as Lysteda, and whether or not this drug can decrease menstrual blood loss in young women and lead to an increase in the quality of life.
- Trial name
- NCT01846507
- Testing
- Tranexamic Acid
- Where
- 5 sites in United States
- Volunteers
- 32 people
- Sponsor
- Nationwide Children's Hospital
Menorrhagia, Dysmenorrhea
Prospective, Non-interventional, Multi-center Safety Study of Mirena for Heavy Menstrual Bleeding and Dysmenorrhea
The primary objective in this study is collecting post-marketing information on the safety. Thus, it includes information under the routine clinical practice on adverse events (AEs) and adverse drug reactions (ADRs) including…
- Trial name
- J-MIRAI (NCT02475356)
- Testing
- Levonorgestrel IUS (Mirena, BAY86-5028)
- Where
- Japan
- Volunteers
- 601 people
- Sponsor
- Bayer
Hemophilia, Menstrual Flow Excessive
Extended Half Life Factor (EHF) Products For Heavy Menstrual Bleeding in Hemophilia Carriers
The purpose of this feasibility study is to find out if two clotting factor products, Eloctate [hemophilia A] and Alprolix [hemophilia B], can reduce the amount of menstrual bleeding in female hemophilia A and B carriers (14…
- Trial name
- NCT03272568
- Testing
- Recombinant FVIII Fc fusion product Eloctate, Recombinant FIX Fc fusion product Alprolix, Patient-operated diagnostic device for anemia AnemoCheck.
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Emory University
Von Willebrand Diseases
Minimize Menorrhagia in Women With Von Willebrand Disease
This is an outpatient, 24-week Phase III prospective, randomized, crossover trial comparing recombinant von Willebrand factor (rVWF) and tranexamic acid (TA, Lysteda®) to minimize menorrhagia in women with von Willebrand disease…
- Trial name
- VWDMin (NCT02606045)
- Testing
- recombinant von Willebrand factor, tranexamic acid
- Where
- 19 sites in United States
- Volunteers
- 39 people
- Sponsor
- Margaret Ragni
Heavy Menstrual Bleeding, Bleeding Disorder
Hormonal Management of Heavy Menstrual Bleeding in Adolescents
The goal of this study is to evaluate whether hormonal medications (such as contraceptive pill, patch, injectable progestins and hormonal intra-uterine device) have similar efficacy at managing heavy menstrual bleeding in…
- Trial name
- JAdoRE (NCT06740929)
- Where
- Switzerland
- Volunteers
- 163 people
- Sponsor
- University Hospital, Geneva
Dysmenorrhea, Heavy Menstrual Bleeding
Ultrasound Evaluation Versus Direct Measurement of Uterine Cavity Length
To determine if uterine cavity length on transabdominal pelvic ultrasound corresponds to uterine cavity length at time of IUD insertion.
- Conditions
- Dysmenorrhea, Heavy Menstrual Bleeding, Contraception
- Trial name
- NCT04425577
- Testing
- Transabdominal Ultrasound
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Children's Mercy Hospital Kansas City
Iron Deficiency Anemia, Heavy Menstrual Bleeding
Alternate Day Versus Daily Oral Iron Therapy in Adolescents
Iron deficiency anemia affects over half of girls and young women with heavy periods and is the most common cause of anemia worldwide.
- Conditions
- Iron Deficiency Anemia, Heavy Menstrual Bleeding, Abnormal Uterine Bleeding
- Trial name
- NCT05007899
- Testing
- Ferrous sulfate
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Menorrhagia
Lysteda Pediatric Research Equity Act (PREA) Pharmacokinetic Study in Adolescent Females With Heavy Menstrual Bleeding
This is a Phase 4, randomized, 2-way crossover, pharmacokinetic study of Lysteda (tranexamic acid) tablets administered as single doses of 0.65 g and 1.3 g in fasting adolescent female subjects ages 12-16 years with heavy…
- Trial name
- PREA (NCT01190150)
- Testing
- tranexamic acid
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Ferring Pharmaceuticals
Heavy Menstrual Bleeding
A Study Called Champion-HMB to Learn More About Females With Heavy Menstrual Bleeding and Available Treatments to Enable Earlier Diagnosis and to Predict Courses of Treatment
This is an observational study in which patient data from the past of females with heavy menstrual bleeding (HMB) is studied. HMB describes menstrual periods with abnormally heavy or prolonged bleeding.
- Trial name
- Champion-HMB (NCT05176496)
- Where
- Germany
- Volunteers
- 99,999 people
- Sponsor
- Bayer
Heavy Menstrual Bleeding
Impact of Incomplete Endometrial Ablation
The aim of the proposed protocol is to study the impact of incomplete endometrial ablation on the PBAC score, reintervention, satisfaction, controlled bleeding and dysmenorrhea at 24 months after Novasure endometrial ablation, in…
- Trial name
- NCT06122363
- Testing
- hysteroscopy
- Where
- Netherlands
- Volunteers
- 121 people
- Sponsor
- Maxima Medical Center
Laparoscopic Myomectomy
A Retrospective Review Of Outcomes Following Laparoscopic Myomectomy
This will be a retrospective review of approximately 900 patients who have undergone laparoscopic myomectomy since 1999. patients will be contacted by phone and surveyed.
- Trial name
- retromyo (NCT00672750)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- The Advanced Gynecologic Surgery Institute
Menorrhagia
Pattern of Menorrhagic Female Attending the Hematology Unit in Assuit University Children Hospital
To Evaluate Causes of Menorrhagia in Adolescent FemalesSpecially Hematological causes to help in management of abnormal uterine bleeding.
- Trial name
- Menorrhagia (NCT06660459)
- Volunteers
- 50 people
- Sponsor
- Assiut University
Hypermobile Ehlers-Danlos Syndrome, Heavy Menstrual Bleeding
Identifying the Determinants of Bleeding and Hypermobility in Patients With Heavy Menstrual Bleeding
In this study, researchers want to learn about the connection between heavy bleeding issues and joint hypermobility (loose joints).
- Conditions
- Hypermobile Ehlers-Danlos Syndrome, Heavy Menstrual Bleeding, Hypermobility Syndrome (Disorder)
- Trial name
- NCT05685199
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- St. Jude Children's Research Hospital
Menorrhagia
Prevalence and Impact on Quality of Life, Academic Performance, and Blood Indices of Heavy Menstrual Bleeding Among Female Students in Assiut University, Egypt
The cause of menstrual disorders is unknown because many female students, embarrassed or unsure of what is "normal," never seek care.
- Trial name
- menorrhagia (NCT07188259)
- Where
- Egypt
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Assiut University
Menorrhagia, Metrorrhagia
Tamoxifen to Reduce Unscheduled Bleeding in New Users of the Levonorgestrel-releasing Intrauterine System (LNG-IUS)
This study evaluates the ability of tamoxifen to improve frequent or prolonged bleeding in new users of the 52mg levonorgestrel-releasing intrauterine device (IUD).
- Conditions
- Menorrhagia, Metrorrhagia, Medicated Intrauterine Devices
- Trial name
- NCT02824224
- Testing
- Tamoxifen
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Menorrhagia
RCT Novasure Versus Novasure + Mirena IUS in the Treatment of Menorrhagia
Hypothesis. Combined treatment with novasure and mirena IUS confers benefit over Novasure alone in the treatment of menorrhagia
- Trial name
- NCT01965587
- Testing
- novasure mirena IUS combined
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Walsall Healthcare NHS Trust
Heavy Menstrual Bleeding
Evaluating the Reliability and Validity of the Arabic Version of the SAMANTA Questionnaire: A Step Toward Improved Diagnosis of Heavy Menstrual Bleeding
Heavy menstrual bleeding (HMB) significantly impacts women's quality of life (QoL). However, despite the high prevalence of HMB, culturally adapted screening tools remain scarce in our locality.
- Trial name
- NCT07267611
- Volunteers
- 120 people
- Sponsor
- Assiut University
Heavy Menstrual Bleeding
Delivering tAN to Reduce HMB: The LUNA Study
The LUNA study is a prospective, randomized, double-blind, sham-controlled, decentralized clinical trial in participants with heavy menstrual bleeding of no known structural cause.
- Trial name
- LUNA (NCT07326722)
- Testing
- Sparrow Link
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Spark Biomedical, Inc.
Dysmenorrhea, Heavy Menstrual Bleeding
Menstrual Complaints in Adolescents and Adults
The aim of this study is to investigate the prevalence of menstrual complaints and their impact on daily life activities (school/work absence, absence from social activities, sports) in adults and adolescents.
- Conditions
- Dysmenorrhea, Heavy Menstrual Bleeding, Daily Activities, Menstrual Cramps
- Trial name
- MEK app (NCT06921629)
- Testing
- Menstruatie Educatie Kalender (Menstrution Education Calendar) application (MEK-app), Questionnaires
- Where
- Netherlands
- Volunteers
- 2,000 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)