Clinical trials: Mesenchymal Stem Cell
Sever Aplastic Aneia, Children
A Randomized, Controlled Clinical Study on the Efficacy and Safety of Umbilical Cord Mesenchymal Stem Cells Combined With Standard Immunosuppressants in the Treatment of Children With Severe Aplastic Anemia
Study on the efficacy and safety of umbilical cord mesenchymal stem cells combined with standard immunosuppressive agents in the treatment of children with acquired severe aplastic anemia
- Conditions
- Sever Aplastic Aneia, Children, Umbilical Cord Mesenchymal Stem Cells
- Trial name
- SAA MSC (NCT07903649)
- Testing
- Umbilical Cord Mesenchymal Stem Cells with ATG/ALG, ATG/ALG
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Hepatitis-associated Aplastic Anemia, Severe Aplastic Anemia(SAA)
Clinical Study of UC-MSC Combined With Immunosuppressive Agents in the Treatment of Pediatric HAAA
The goal of this clinical trial is to evaluate the effectiveness of umbilical cord mesenchymal stem cells combined with standard immunosuppressive therapy in children with HAAA, and to provide a new therapeutic idea for children…
- Conditions
- Hepatitis-associated Aplastic Anemia, Severe Aplastic Anemia(SAA), Umbilical Cord Blood, Mesenchymal Stem Cells
- Trial name
- NCT07850362
- Testing
- UC-MSC
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Biliary Atresia, Kasai Portoenterostomy
Clinical Outcomes of Early Kasai Surgery With Umbilical Cord MSCs in Biliary Atresia
The goal of this clinical trial with historical control is to evaluate whether umbilical cord-derived mesenchymal stem cell (UC-MSC) therapy can improve clinical outcomes in infants with biliary atresia undergoing Kasai surgery…
- Conditions
- Biliary Atresia, Kasai Portoenterostomy, Mesenchymal Stem Cell Transplantation, Liver Function Disorders
- Trial name
- NCT07011199
- Testing
- Umbilical Cord-Derived Mesenchymal Stem Cells (UC-MSCs), Kasai Portoenterostomy
- Where
- Indonesia
- Volunteers
- 14 people
- Sponsor
- Universitas Diponegoro
Multiple Sclerosis, Secondary-Progressive Multiple Sclerosis
Evaluate the Safety and Feasibility of Allogeneic Mesenchymal Stem Cells in Patients With Multiple Sclerosis
To assess the safety and of a single dose of IV infusion of placenta derived Mesenchymal Stem Cells (PLMSCs) in patients with secondary progressive Multiple Sclerosis (SPMS) disease.
- Conditions
- Multiple Sclerosis, Secondary-Progressive Multiple Sclerosis, Mesenchymal Stem Cells
- Trial name
- MS (NCT06360861)
- Testing
- Allogenic placenta derived mesenchymal stem cells
- Where
- Iran
- Volunteers
- 5 people
- Sponsor
- Tehran University of Medical Sciences
Diabete Type 2, Mesenchymal Stem Cell
Longterm Follow-up of Subjects With Diabetes 2 Type Treatment With ex Vivo Gene Therapy
This is a multicenter, long term safety and efficacy follow up study for with insulin dependent diabetes 2 type who have been treated with ex vivo gene therapy product in Ukraine Association of Biobank bio-sponsored clinical…
- Trial name
- AUB001 (NCT04642911)
- Testing
- Long term follow up
- Where
- Ukraine
- Volunteers
- 91 people
- Sponsor
- Ukraine Association of Biobank
Graft Vs Host Disease, Oral Mucositis (Ulcerative)
Treatment of Oral Mucositis Using Platelet Rich Fibrin TREATMENT OF ORAL MUCOSITIS USING PRF
Oral mucositis (OM) is an inflammatory mucosal demolition frequently observed during treatments for neoplastic diseases such as chemotherapy or radiation therapy.
- Conditions
- Graft Vs Host Disease, Oral Mucositis (Ulcerative), Mesenchymal Stem Cells
- Trial name
- NCT05018754
- Testing
- TREATMENT OF ORAL MUCOSITIS USING PLATELET-RICH-FIBRIN (PRF)
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- University of Rome Tor Vergata
Spinal Tuberculosis, Mesenchymal Stem Cell
Effectivity of Mesenchymal Stem Cell on Vertebral Bone Defect Due to Mycobaterium Tuberculosis Infection
This study evaluates the effectiveness of locally implantation of mesenchymal stem cell on vertebral bone defects due to infection of mycobacterium tuberculosis.
- Trial name
- NCT04493918
- Testing
- Mesenchymal Stem cell + Nacl 0.9%, NaCl 0.9%
- Where
- Indonesia
- Volunteers
- 20 people
- Sponsor
- Ahmad Jabir Rahyussalim
Evaluate the Safety and Effectiveness of Mesenchymal Stem Cell Conditioned Medium-derived Pleiotropic Factor in Treating Donor Sites
Mesenchymal Stem Cell-derived Pleiotropic Factor in the Treatment of Donor Sites
Skin grafting is a standard treatment for deep wounds, but care of the donor site after transplantation is very important. The means of accelerating wound healing can increase overall patient satisfaction.
- Trial name
- NCT04234750
- Testing
- mesenchymal stem cell conditioned medium-derived pleiotropic factor
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Chinese PLA General Hospital
Mesenchymal Stem Cell-derived Pleiotropic Factor in Treating Residual Burn Wound
Mesenchymal Stem Cell Conditioned Medium-derived Pleiotropic Factor in Treating Residual Burn Wound
Treatment of extensive deep burn residual wounds is a common problem in burn plastic surgery. Due to bacterial invasion, excessive maturation of granulation tissue, poor abrasion resistance of new epithelium, and coexistence of…
- Trial name
- NCT04235296
- Testing
- epidermal growth factor, mesenchymal stem cell conditioned medium-derived pleiotropic factor
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Chinese PLA General Hospital
Lupus Nephritis, Mesenchymal Stem Cells
Allogeneic Amniotic Mesenchymal Stem Cell Therapy for Lupus Nephritis
This study would further evaluate the safety and efficacy of human amniotic mesenchymal stem cell (hA-MSC) for the treatment of lupus nephritis (LN).
- Trial name
- NCT04318600
- Testing
- human amniotic mesenchymal stem cell
- Volunteers
- 16 people
- Sponsor
- Yan'an Affiliated Hospital of Kunming Medical University
Intracranial Hemorrhages, Mesenchymal Stem Cells
Follow-Up Study of Safety of Pneumostem® in Premature Infants With Intraventricular Hemorrhage
This is a follow-up study of the open label, single-center, phase I clinical trial to evaluate the safety of Pneumostem® in premature infants with Intraventricular hemorrhage.
- Conditions
- Intracranial Hemorrhages, Mesenchymal Stem Cells, Newborn Infant
- Trial name
- NCT02673788
- Testing
- observation without intervention in this follow up study
- Where
- South Korea
- Volunteers
- 9 people
- Sponsor
- Samsung Medical Center
Stem Cell Transplantation, Hematopoietic, Mesenchymal Stem Cells
Mesenchymal Stem Cells for Treatment of Poor Graft Function After Allogeneic Hematopoietic Stem Cell Transplant
The purpose of this study is to evaluate the utility of treating patients experiencing poor graft function after allogeneic hematopoietic stem cell transplantation with ex-vivo-expanded BM-drived mesenchymal stem cells from…
- Conditions
- Stem Cell Transplantation, Hematopoietic, Mesenchymal Stem Cells, Poor Graft Function, Hematological Diseases
- Trial name
- NCT01763086
- Testing
- Mesenchymal stem cells
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Hematopoietic Stem Cell Transplantation, Mesenchymal Stem Cells
Mesenchymal Stem Cells Combined With Cord Blood for Treatment of Graft Failure
The purpose of this study is to evaluate the utility of treating patients experiencing graft failure after autologous hematopoietic stem cell transplantation with ex-vivo-expanded BM-drived mesenchymal stem cells from third-party…
- Conditions
- Hematopoietic Stem Cell Transplantation, Mesenchymal Stem Cells, Umbilical Cord Blood, Graft Failure
- Trial name
- NCT01763099
- Testing
- Mesenchymal stem cells, Mesenchymal stem cells and cord blood
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Liver Failure, Mesenchymal Stem Cells
Therapeutic Effects of Liver Failure Patients Caused by Chronic Hepatitis B After Autologous MSCs Transplantation
The study aimed to investigate the short-term efficacy and long-term prognosis of liver failure patients caused by hepatitis B after single transplantation with autologous marrow mesenchymal stem cells (MMSCs).
- Trial name
- NCT00956891
- Where
- China
- Volunteers
- 158 people
- Sponsor
- Sun Yat-sen University
Diabetes Mellitus, Diabetes Mellitus, Type 1
Umbilical Cord Mesenchymal Stem Cells Infusion for Initial Type 1 Diabetes Mellitus
The purpose of this study is to determine whether umbilical cord Mesenchymal Stem Cells of treatment for initial type 1 diabetes is safe and effective.
- Conditions
- Diabetes Mellitus, Diabetes Mellitus, Type 1, Mesenchymal Stem Cells, Umbilical Cord
- Trial name
- NCT01219465
- Testing
- umbilical cord mesenchymal stem cells
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Qingdao University
Sjogren's Syndrome, Mesenchymal Stem Cells
Allogeneic Mesenchymal Stem Cells Transplantation for Primary Sjögren's Syndrome (pSS)
This study will explore safety and efficacy of allogeneic mesenchymal stem cells transplantation (MSCT) to treat patients with diagnosis of primary Sjögren's Syndrome (pSS) who have been resistant to multiple standard treatments.
- Trial name
- NCT00953485
- Testing
- Allogeneic Mesenchymal Stem Cells (AlloMSC)
- Where
- China
- Volunteers
- 20 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Systemic Sclerosis, Mesenchymal Stem Cells
Allogeneic Mesenchymal Stem Cells Transplantation for Systemic Sclerosis (SSc)
This study will explore safety and efficacy of allogeneic mesenchymal stem cells transplantation (MSCT) to treat patients with diagnosis of systemic sclerosis(SSc) who have been resistant to multiple standard treatments.
- Trial name
- NCT00962923
- Testing
- Allogeneic Mesenchymal Stem Cells (AlloMSC)
- Where
- China
- Volunteers
- 20 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School