Clinical trials: Metabolic Diseases
Adolescent Obesity, Hypertension,Essential
Treatment and Handling Severe Obesity-Related Comorbidities in Adolescents Through Exercise
The main objective of this project is to analyze the effect of a tailor-made, one-to-one, exercise program (aiming to treat and handle obesity-related comorbidities in adolescents with severe obesity at high risk of…
- Conditions
- Adolescent Obesity, Hypertension,Essential, Non-Alcoholic Fatty Liver Disease, Dyslipidemias
- Trial name
- THOR-X (NCT06520800)
- Testing
- Treatment and handling obesity-related comorbidities in adolescents through exercise
- Volunteers
- 24 people
- Sponsor
- University of Lisbon
Hypertension
Post-marketing Surveillance for Hypertensive Patients With Diabetes and/or Chronic Kidney Disease
This study is a post-marketing surveillance in Japan, and it is a local prospective, company sponsored and observational study of patient who have been treated by Adalat CR for hypertension with diabetes and/or chronic kidney…
- Trial name
- NCT01363336
- Testing
- Nifedipine (Adalat CR, BAYA1040)
- Where
- Japan
- Volunteers
- 1,882 people
- Sponsor
- Bayer
Type 1 Diabetes
Novel mHealth Physical Activity Intervention for Youth With Type 1 Diabetes Mellitus
The goal of this longitudinal cohort study is to learn about a mHealth intervention in Type 1 Diabetes (T1D) The main question[s] it aims to answer are: Does the intervention increase the amount of text messages between the…
- Trial name
- NCT06018844
- Testing
- NUDGE
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Children's Mercy Hospital Kansas City
Adolescent Obesity, Life Style, Healthy
CArdioMetabolic Prevention in Adolescents
The aim of the CArdioMetabolic Prevention (CAMP) pilot study is to investigate the effect of a group intervention on lifestyle in adolescents and on at least one adult family member.
- Conditions
- Adolescent Obesity, Life Style, Healthy, Body Weight Changes, Cardiometabolic Syndrome
- Trial name
- CAMP (NCT05350111)
- Testing
- lifestyle education
- Where
- Czechia
- Volunteers
- 40 people
- Sponsor
- Faculty Hospital Kralovske Vinohrady
Morbid Obesity
Effect of Gastric Balloon in Morbid Obesity: Prospective Study
The aim of this study is to compare the efficacy of gastric balloon in weight reduction among two different categories of morbidly obese people.
- Trial name
- NCT02128165
- Testing
- BMI more than 45 BMI, BMI less than 45 BMI
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Nephrocalcinosis
Prevalence and Risk Factors of Nephrocalcinosis in Children at Sohag University Hospital
To study prevalence, risk factors, possible etiologies, clinical presentation and outcome of nephrocalcinosis in children at Sohag University Hospital.
- Trial name
- NCT05862207
- Volunteers
- 50 people
- Sponsor
- Sohag University
Cholestatic Liver Disease, Chronic Liver Disease (CLD)
Vitamin D2 vs Vitamin D2 Plus Calcitriol in Cholestatic Children With Vitamin D Deficiency
The goal of this clinical trial is to learn whether adding calcitriol to vitamin D2 can improve vitamin D deficiency in children with cholestasis and chronic liver disease.
- Conditions
- Cholestatic Liver Disease, Chronic Liver Disease (CLD), Vitamin D Deficiency, Children
- Trial name
- VITD-CHOL (NCT07670611)
- Testing
- Vitamin D2, Calcitriol
- Where
- Thailand
- Volunteers
- 54 people
- Sponsor
- Chulalongkorn University
Child Development
LIFE Child (LIFE Leipzig Research Centre for Civilization Diseases)
The Leipzig Research Centre for Civilization Diseases (LIFE) Child Study is a prospective longitudinal population-based study with a life course approach to health and disease.
- Trial name
- NCT02550236
- Where
- Germany
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Infant Development, Infant Overnutrition
Measurement of Energy Metabolism in Infants
The purpose of this study is to measure energy expenditure during the first 3 months of life in infants.
- Trial name
- BabyEE Pilot (NCT02683473)
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Cystic Fibrosis, Glucose Metabolism Disorders
One Year Glargine Treatment in CFRD Children and Adolescents
Glargine treatment can improve the clinical features in Cystic Fibrosis patients affected by glucose derangements
- Trial name
- NCT00483769
- Testing
- Glargine
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Federico II University
IDA - Iron Deficiency Anemia, Anemia
Iron Deficiency Anemia (IDA) and the Brain
This is a trial with an observational and an interventional arm, in patients with moderate to severe anemia and control subjects.
- Conditions
- IDA - Iron Deficiency Anemia, Anemia, Iron Deficiency Anemia, Anemia, Iron Deficiency
- Trial name
- IDA (NCT05929729)
- Testing
- Ferric derisomaltose, NovaFerrum
- Where
- 4 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Hepatic Encephalopathy
ETOS: Minimal Hepatic Encephalopathy in Childhood and Young Adult: epidemiOlogical Study and Pilot Interventional Study
The aim of the study is: Epidemiological/observational: investigating the presence of neuropsychological and electrophysiological alterations, suggesting a condition of minimal hepatic encephalopathy(and its behavioral…
- Trial name
- ETOS (NCT01798329)
- Testing
- probiotic VSL#3
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII
Bloom Syndrome
Biological Significance of the Bloom's Syndrome Protein
Since 1960, persons with the very rare disorder Bloom's syndrome (BS) have been followed clinically, documenting clinical matters as obtained from their doctors.
- Trial name
- NCT00021437
- Where
- United States
- Sponsor
- National Center for Research Resources (NCRR)
Osteoporosis
Building Better Bones in Children
Calcium is important for healthy bone growth in children. Poor bone growth and development during childhood can lead to osteoporosis later in life.
- Trial name
- NCT00063037
- Testing
- Behavioral modification - nutrition education
- Where
- United States
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Familial Hypercholesterolemia
Soy Food Intervention Trial
Familial hypercholesterolemia (FH MIM#143890), an inherited disorder of lipoprotein metabolism, is a risk for early cardiovascular disease (CVD).
- Trial name
- SOYFIT (NCT00924339)
- Testing
- soy protein diet, rapeseed oil
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Pediatric Obesity
Appetite Response to Exercise- Versus Mixed (Exercise + Dietary Restriction)-Induced Energy Deficit in Adolescents With Obesity
The aim of the present study is to compare the effect of iso-energetic energy deficits induced by energy restriction alone or exercise + dietary restriction (Mixed deficit) on energy intake and appetite feelings in adolescents…
- Trial name
- IDEX2 (NCT04734639)
- Testing
- CON . control condition without exercise / rest condition, Def-Mixed. Condition with a mixed energy deficit induced by exercise + dietary restriction., Def-EI. Condition with an energy-restriction energy deficit
- Where
- France
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Wilson Disease, D-Penicillamine
Wilson's Disease Treated With D-Penicillamine: Characterization of Skin Damage Secondary to Treatment by Measuring Skin Elasticity
Wilson's disease is a genetic disorder, resulting from an anomaly present on the ATP7B gene located on chromosome 13, causing a progressive accumulation of copper in various organs such as the liver, nervous system and cornea…
- Conditions
- Wilson Disease, D-Penicillamine, Effect of D-penicilline on Cutaneous Elastity of Wilson's Patient
- Trial name
- WILDERME (NCT06945081)
- Testing
- Preparation of forearm molds with SILFLO® silicone
- Where
- 2 sites in France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Diabetes, Diabetes Mellitus, Type 2
Observational Study to Investigate the Efficacy and Safety of Human Insulin or Insulin Analogue Treatments in Type 2 Diabetes Subjects
This study is conducted in Asia. The aim of this observational study is to investigate the percentage of patients reaching the treatment target on blood glucose control after treatment with either human insulin or insulin…
- Trial name
- NCT00806936
- Testing
- human insulin, insulin analogue
- Where
- China
- Volunteers
- 4,847 people
- Sponsor
- Novo Nordisk A/S
Overweight Adolescents, Overweight
Pilot Program for Targeted Prevention of Child or Adolescent Weight Gain
This study will examine whether family-based interpersonal psychotherapy (FB-IPT) is an effective tool for helping pre-adolescent girls and boys at risk for become obese to reduce weight gain.
- Trial name
- NCT00263536
- Testing
- Interpersonal Psychotherapy
- Where
- United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Infant, Very Low Birth Weight, Infant Malnutrition
Near Infrared Spectroscopy (NIRS) and Superior Mesenteric Artery (SMA) Doppler Patterns as Predictor of Feeding Tolerance in Very Low Birth Weight (VLBW) IntraUterine Growth Restricted (IUGR) and NON IUGR Infants
This study aims at recruiting about twenty very low birth weight infants, either intrauterine growth restricted (IUGR) or NON-IUGR STRATIFICATION:Population will be stratified in two groups: IUGR infants (approximately 10…
- Conditions
- Infant, Very Low Birth Weight, Infant Malnutrition, Feeding Disorder of Infancy or Early Childhood, Splanchnic Oximetry
- Trial name
- NCT01341236
- Testing
- different nutrional regimen, comparison of different feeding regimens
- Where
- Italy
- Volunteers
- 41 people
- Sponsor
- San Gerardo Hospital
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