Clinical trials: Metabolic Regulation
Obesity
A Study to Determine the Effectiveness of a Self-regulation Program to Treat Pediatric Obesity
The objective of this study is to pilot test, evaluate and compare the effects of Cue Reactivity and Sensitivity Training (CRST) and Children's Appetite Awareness Training (CAAT) in 48 children aged 8-12 years old.
- Trial name
- ROC (NCT01442142)
- Testing
- CAAT: Appetite Awareness, CRST: Volcravo, Combined CAAT and CRST program
- Where
- United States
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Childhood Obesity, Breastfeeding
Breastfeeding in Infancy and Food Intake in Preschool-Aged Children
The purpose of this study is to compare female, preschool-aged children breastfed during infancy to female, preschool-aged children bottle-fed during infancy in their ability to adjust calorie intake in response to internal…
- Trial name
- NCT00994487
- Testing
- High Energy Density Preload, Low Energy Density Preload
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Vitamin D Deficiency, Immunosuppression
Helminth Infection During Pregnancy on Vitamin D Regulation: HELMVIT Study
Purpose: To examine whether helminth infection during pregnancy alters Vitamin-D-metabolism and reactivity of the child's immune system Hypothesis: Helminth infection during pregnancy is associated with altered Vitamin D levels…
- Trial name
- HELMVIT (NCT04324853)
- Testing
- Microscopy ( Urine filtration), UCAA test, qPCR,, Microscopy (Kato Katz, Coproculture, Harada Mori, MIF), qPCR,
- Where
- Gabon
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Centre de Recherche Médicale de Lambaréné
Appetite Self-regulation, Pediatric Obesity
Food Form & Energy Intake
This study primarily aims to examine how food presented in various forms (i.e., solid, semi-solid, and liquid) affects children's ability to self-regulate energy intake at a subsequent meal.
- Trial name
- NCT05258097
- Where
- 2 sites in United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Penn State University
Obesity
Impact of High Fiber Snacks on Adiposity, Glucose Regulation and Appetite
The primary objective of the proposed research is to determine the influence of 8 weeks of twice daily consumption of 120 kcal servings of dried apples or a commonly consumed low fat 120kcal muffin on components of obesity (waist…
- Trial name
- NCT02217124
- Testing
- dried apples, muffin
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Binge-Eating Disorder, Obesity
Precursors of Binge Eating Disorder in a Clinical Sample of Adolescents With Obesity
BACKGROUND: Binge eating disorder (BED) is the worldwide most-prevalent eating disorder. It is associated with psychiatric comorbidities and obesity, a high impact in life functioning, and high morbidity and mortality.
- Conditions
- Binge-Eating Disorder, Obesity, Eating Disorders, BED
- Trial name
- PREC-BED (NCT06387719)
- Testing
- Magnetic resonance imaging
- Where
- Spain
- Volunteers
- 102 people
- Sponsor
- Fundació Sant Joan de Déu
Childhood Obesity
Efficacy of ENTREN-F Program: A Psycho-family Intervention in Childhood Obesity
ENTREN-F Programme describes a novel structured psychosocial family-based intervention from Primary Care using a train trip metaphor aimed at improving healthy lifestyles for the whole family.
- Trial name
- ENTREN-OB (NCT04465799)
- Testing
- ENTREN, ENTREN-F, Control group
- Where
- Spain
- Volunteers
- 180 people
- Sponsor
- Universidad Autonoma de Madrid
Cerebral Blood Flow, Cerebral Blood Flow Regulation
The Role of Estrogen and Testosterone in Determining Brain Blood Flow and Metabolic Regulation in Humans
Due to historical exclusion of females from research, there are gaps in the understanding of female physiology, how it differs from males, and how sex-specific hormones contribute.
- Conditions
- Cerebral Blood Flow, Cerebral Blood Flow Regulation, Sex Differences, Exercise
- Trial name
- NCT07212712
- Testing
- GnRH antagonist, Estradiol (E2), Testosterone
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Food Intake Regulation, Substrate Oxidation
Substrate Oxidation Does Not Affect Short Term Food Intake in Healthy Boys and Men
The purpose of this study is to investigate the effect of substrate oxidation, expressed by RER, on food intake regulation and net energy balance.
- Trial name
- NCT01888991
- Testing
- Glucose Preload and Exercise Intervention
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Type 2 Diabetes, Obesity
Obesity and Diabetes Prevention Through Science Enrichment
Type 2 diabetes and obesity in children continue to increase at alarming rates with devastating results. However, both these metabolic diseases are largely preventable through adoption of a healthy lifestyle, an understanding of…
- Trial name
- DKENERGY (NCT00541879)
- Testing
- Program ENERGY, comparison
- Where
- United States
- Volunteers
- 2,909 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Head Injury
Effect of Intrathoracic Pressure Regulation on Traumatic Brain Injury
The purpose of this study is to demonstrate proof of clinical concept that application of the Intrathoracic Pressure Regulator (ITPR) will result in an increase in Cerebral Perfusion Pressure (CPP) and a decrease in Intracranial…
- Trial name
- NCT01824589
- Testing
- -7 cm H2O ITPR, -12cm H2O ITPR
- Volunteers
- 1 people
- Sponsor
- Advanced Circulatory Systems
Obesity and Type 2 Diabetes, Diet Modification
Mobile Regulation of Craving Training (mROC-T) to Improve Dietary Intake in Rural Adolescent Girls
The goal of this clinical trial is to test if a regulation of craving training intervention in the form of a mobile phone app can increase fruit and vegetable intake in adolescent girls ages 14-18 years of age.
- Trial name
- ROC Teens! (NCT06723028)
- Testing
- Regulation of craving training
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Wyoming
Polycystic Ovary Syndrome (PCOS), Obesity &Amp;Amp; Overweight
Strengthening Healthy Emotional Co-regulation of Mothers With PCOS and Obesity and Their Infants
It is both timely and important to invest in interventions that can improve healthy emotional co-regulation. It is proposed to evaluate the feasibility and limited efficacy of an adapted, brief, multimodal intervention: ECoFam…
- Trial name
- ECoFam (NCT07129434)
- Testing
- ECoFam
- Where
- Finland
- Volunteers
- 40 people
- Sponsor
- Oulu University Hospital
Overweight and Obesity
FRESH-TEEN: Families Responsibility Education Support Health for Teens
The objective of this proposed study is to collect initial efficacy data on a behavioral weight loss (BWL) program for teens, which also includes emotion regulation strategies (ER), to standard BWL.
- Trial name
- FRESH-TEEN (NCT03674944)
- Testing
- Behavioral Weight Loss (BWL) + Emotion Regulation (ER), Behavioral Weight Loss (BWL)
- Where
- 2 sites in United States
- Volunteers
- 332 people
- Sponsor
- University of California, San Diego
Overweight Adolescents, Obese Adolescents
Pilot Testing a Novel Approach to Pediatric Obesity Treatment
The goal of this clinical trial is to learn if an emotion regulation and self-monitoring intervention can help treat overweight and obesity in teens.
- Trial name
- NCT06755827
- Testing
- Emotion regulation and self-monitoring to treat pediatric obesity, Psychoeducation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Texas Tech University
Diabetes Mellitus, Type 1
Blood Glucose Awareness Training for Parents
The purpose of this study is to test a training program for parents of children with T1DM.
- Trial name
- NCT00315991
- Testing
- Blood Glucose Awareness Training for Parents
- Where
- 2 sites in United States
- Volunteers
- 77 people
- Sponsor
- University of Virginia
Type 1 Diabetes Mellitus
Efficacy of the "Living With Type 1 Diabetes to Grown-Up" Interactive Podcast Program
The present study aims to evaluate the intervention effectiveness of the Online Interactive Podcast Program"Living with Type 1 Diabetes to Grown-Up"in patients with type 1 diabetes transitioning from adolescence to early…
- Trial name
- NCT06464640
- Testing
- Online Interactive Podcast Program "Living with Type 1 Diabetes to Grown-Up", E-book
- Where
- Taiwan
- Volunteers
- 88 people
- Sponsor
- Chang Gung University
Overweight and Obesity
Improving Emotion Regulation Skills Among Adolescents Attempting to Lose Weight
While the prevalence of overweight and obesity among children and adolescents has plateaued, national data indicate that approximately 35% of children and adolescents continue to struggle with overweight/obesity.
- Trial name
- NCT03393221
- Testing
- ER, SBWC
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Intestinal Failure
Spectral Lighting and Metabolism
The goal of this exploratory n-of-1-study is to compare markers of metabolism in infants in a Level IV Neonatal Intensive Care Unit (NICU) between two lighting environments.
- Trial name
- NCT06094504
- Testing
- Spectral Lighting
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Obesity
Diet Composition - Metabolic Regulation and Long-term Compliance
This study will compare a high-protein/low-carbohydrate diet (modified paleolithic diet, MPD) with a diet high in slow carbohydrates (Nordic Nutrition Recommendations, NNR).
- Trial name
- KNOTA (NCT00692536)
- Testing
- NNR (Nordic Nutrition Recommendations), MPD (Modified paleolithic diet)
- Where
- Sweden
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Umeå University