Clinical trials: Methylphenidate
Attention Deficit Hyperactivity Disorder
Expectation of Driving Performance in Young Adults With ADHD Assessed by Driving Simulator and Seat Pressure Mapping
Adolescents suffering of ADHD may have impaired driving performance. The investigators would like to check the differences in driving performance in young adults(aged: 15-18 years) with ADHD by driving simulator and seat pressure…
- Trial name
- NCT01179386
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Attention Deficit Hyperactivity Disorder
OT and Social Cognition in Children With ADHD: Impact of MPH
Background: The current study aimed to explore the possible effect of stimulants on oxytocin (OT), a neuropeptide found to regulate social behavior, as a mediator of the pro-social effect of methylphenidate (MPH) in children with…
- Trial name
- NCT03788902
- Testing
- Ritalin
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Shalvata Mental Health Center
Acute Lymphoblastic Leukemia, Brain Tumors
Learning Impairments Among Survivors of Childhood Cancer
Children surviving some types of cancer have a higher risk of developing learning problems after cancer treatment than do children who have not had cancer or its treatment.
- Trial name
- NCT00576472
- Testing
- Methylphenidate
- Where
- 3 sites in United States
- Volunteers
- 469 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Attention Deficit Hyperactivity Disorder
The Effect of Methylphenidate Versus Placebo on State Anxiety in Children With Attention Deficit Hyperactivity Disorder.
The purpose of the study is to explore the effect of methylphenidate on state anxiety in children with attention deficit hyperactivity disorder.
- Trial name
- NCT01798459
- Testing
- Methylphenidate
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shalvata Mental Health Center
Attention Deficit Hyperactivity Disorder, ADHD
Imaging Stimulant and Non Stimulant Treatments for ADHD: A Network Based Approach
The growing number of medications used to treat attention-deficit/hyperactivity disorder (ADHD) raises important questions about whether different medications have similar or different therapeutic mechanisms of action.
- Trial name
- NCT01678209
- Testing
- fMRI scans, Atomoxetine arm, Methylphenidate arm
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Attention Deficit Hyperactivity Disorders
Low-dose vs. Normal-dose Psychostimulants on Executive Functions in Individuals With ADHD
This double-blind crossover study aims to compare cognitive performance (e.g., working memory, selective attention and cognitive flexibility) of children ages 6-18 years diagnosed with ADHD of the combined type (ADHD-C) or…
- Trial name
- NCT02167048
- Testing
- Psychostimulants
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Attention Deficit Disorder With Hyperactivity, Dental Caries
Oral Status and Prevalence of Dental Trauma in Children Treated With Ritalin Due to Attention-Deficit Hyperactivity Disorder (ADHD)
To evaluate the dental status of children using ritalin and suffering from ADHA in comparison to healthy children.
- Conditions
- Attention Deficit Disorder With Hyperactivity, Dental Caries, Dental Occlusion, Traumatic
- Trial name
- NCT00328224
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Obesity
The Effects of Methylphenidate on Energy Intake and Energy Expenditure
The Problem: Obesity is one of the leading causes of chronic disease and death. The efficacy of diet and exercise to sustain weight loss over the long term is weak.
- Trial name
- MPH (NCT02754258)
- Testing
- MPH
- Where
- 2 sites in Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Eastern Ontario
Attention Deficit Hyperactivity Disorder
Concerta and Strattera on the Executive Function in Attention Deficit Hyperactivity Disorder (ADHD) Children
The objective of this study is to compare the effect of Concerta (Osmotic Release Oral System Extended Release Methylphenidate HCL, OROS MPH) and Strattera (Atomoxetine) on the laboratory and ecological executive function in…
- Trial name
- NCT01065259
- Testing
- OROS MPH, Atomoxetine
- Where
- China
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Peking University
Attention Deficit Hyperactivity Disorder (ADHD)
The Effect of Methylphenidate Treatment on Oxidative Stress Levels in Children Diagnosed With Attention Deficit Hyperactivity Disorder (ADHD)
The aim of this study is to investigate the effect of methylphenidate treatment on oxidative stress by measuring the levels of Total Oxidant Status (TOS), Total Antioxidant Status (TAS), Oxidative Stress Index (OSI=TOS/TAS)…
- Trial name
- NCT06844812
- Testing
- This is not an interventional study. Patients who are planned to start methylphenidate treatment have been invited to participate in the study.
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Methylphenidate, Metabolomics
Metabolic Mechanisms of the Electrophysiological Biomarkers for Response to Methylphenidate Treatment in Children With ADHD
To explore the relationship of treatment-related changes in electrophysiology and those in metabolomics for identification of the underlying metabolic mechanisms for the electrophysiological effects of methylphenidate in children…
- Trial name
- NCT06073470
- Testing
- methylphenidate
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Attention Deficit Hyperactivity Disorder
Endocrine Disrupting Chemicals and Hormones in ADHD
Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder in children and adolescents. Growth hormone and thyroid function are associated with both physical and neurocognitive development.
- Trial name
- ADHD (NCT04970303)
- Testing
- Methylphenidate
- Where
- Taiwan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Attention Deficit Hyperactivity Disorder
Effect Of Methylphenidate On Balance In Children With Attention Deficit Hyperactivity Disorder
Attention Deficit Hyperactivity Disorder is a neurodevelopmental disorder that may have poor motor coordination and balance control. The effect of Methylphenidate treatment on balance and fall risk is still unclear.
- Trial name
- NCT05522478
- Testing
- Fall risk
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
ADHD, Smoking
Family Risk Analysis of Substance Use in Attention Deficit Hyperactivity Disorder (ADHD) Youth Treated With Concerta
The researchers will study 100 families over three years, each with a child (proband) between the ages of 12-17, with the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) diagnosis of ADHD.
- Trial name
- NCT00181792
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Attention Deficit Hyperactivity Disorder (ADHD)
A Long Term Post-Marketing Study on the EffIcacy and Safety of Osmotic Release Oral System (OROS) Methylphenidate on the Cognitive Functions of Attention Deficit Hyperactivity Disorder (ADHD) Participants
The purpose of this long term post-marketing study is to evaluate the effectiveness and safety of osmotic release oral system methylphenidate hydrochloride (OROS-MPH) in participants with Attention Deficit Hyperactivity Disorder…
- Trial name
- NCT01933880
- Testing
- Osmotic Release Oral System Methylphenidate Hydrochloride (OROS-MPH), No intervention
- Where
- 6 sites in China
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Xian-Janssen Pharmaceutical Ltd.
Attention Deficit Disorder With Hyperactivity
Effects of Ritalin on Postural Stability of Hyper Active Children
Experimental design overview The proposed project is a prospective experimental study design. Children (age <15) suffer from attention deficit hyperactivity disorder (ADHD) that their Parents willing to participate in the study…
- Trial name
- NCT00485797
- Testing
- Ritalin
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Attention Deficit/Hyperactivity Disorder
International Study to Predict Optimised Treatment in Attention Deficit/Hyperactivity Disorder
The aim of the iSPOT-A study is to: 1. identify brain, genetic and cognitive markers of Attention Deficit/Hyperactivity Disorder, and 2.
- Trial name
- NCT00863499
- Testing
- Short Acting Methylphenidate, Long Acting Methylphenidate
- Where
- 7 sites in United States, Australia and 1 more
- Volunteers
- 1,344 people, healthy volunteers welcome
- Sponsor
- BRC Operations Pty. Ltd.
Attention Deficit Hyperactivity Disorder
The Effects of Long-acting Methylphenidate on Academic Activity and Related Constructs in Children With ADHD
This study aims at investigating the direct effects of methylphenidate on school performance of primary school children. Although behavioral effects of this frequently prescribed drug are thoroughly studied (and confirmed), the…
- Trial name
- NCT02501798
- Testing
- Methylphenidate
- Where
- Netherlands
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- VU University of Amsterdam
Attention Deficit Hyperactivity Disorder
Efficacy of Combined Treatment With CoQ10 and Methylphenidate in Children With Attention Deficit Hyperactivity Disorder
The aim of this study is to evaluate the effects of nutritional supplement co-enzyme Q10 (CoQ10) on methylphenidate-treated ADHD children in a randomized, double-blinded, placebo-controlled prospective study.
- Trial name
- NCT02315651
- Testing
- Coenzyme Q10
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
ADHD
Multimodal Magnetic Resonance Imaging Study on the Neural Mechanisms of Remission in Children With ADHD
Attention-deficit/hyperactivity disorder(ADHD) is highly prevalent among children and adolescents and often associated with poor long-term outcomes in adulthood. it is thus a serious public health problem.
- Trial name
- NCT05229627
- Testing
- MPH, ATX
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Peking University Sixth Hospital