Clinical trials: Micronutrients
Folate Deficiency, Vitamin B 12 Deficiency
Effectiveness of Fortification With Folic Acid and Vitamin B12 Among Teenage Girls
Folic acid and vitamin B12 play an interdependent role in key cellular processes, namely deoxyribonucleic acid synthesis, cell division, red blood cell formation, and nervous system myelination.
- Conditions
- Folate Deficiency, Vitamin B 12 Deficiency, Anemia, Megaloblastic, Cognitive Development
- Trial name
- NCT06100146
- Testing
- Folic acid and vitamin B12 fortified flour, Unfortified cereal flour
- Where
- 2 sites in Ethiopia
- Volunteers
- 472 people, healthy volunteers welcome
- Sponsor
- University Ghent
Complementary Feeding, Linear Programming
Optimized Complementary Feeding With or Without Home Fortification Prevents Decrease of Micronutrient and Growth
Malnourished among under-five children characterized by growth faltering is a public health concern in Indonesia. It requires serious action from the governments because of the prevalence of underweight, stunting, and wasting are…
- Conditions
- Complementary Feeding, Linear Programming, Nutritional Status, Micronutrient Deficiency
- Trial name
- NCT03891589
- Testing
- Nutritional education program, Home fortification (Taburia)
- Where
- Indonesia
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Udayana University
Angiogenesis, Fetal Weight
Multiple Micronutrients Supplementation on Angiogenesis and Vasculogenesis Factors, and Fetal Biometry
Multiple micronutrients play an important role during pregnancy, since the decidualization and implantation phases. It has an impact on placentation and remodeling of blood vessels.
- Conditions
- Angiogenesis, Fetal Weight, Pregnancy Related, Nutrient Element Deficiency
- Trial name
- NCT06929793
- Testing
- Multiple Micronutrients, Standard Antenatal Vitamin
- Where
- Indonesia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Dr Cipto Mangunkusumo General Hospital
Genomic
Harmonized Micronutrient Project
The purpose of this trial is to better define how individuals with different genetic make-ups will require different interventions to improve their methylation potential and nutrient status.
- Trial name
- NCT01823744
- Testing
- micronutrient supplementation
- Where
- Brazil
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Physical Fitness, Nutritional Status
Nutrition, Physical Performance & Fitness in Indian School Children
The purpose of this study is to evaluate the effect of nutritional supplement on physical performance measures of apparently healthy school going children in India.
- Trial name
- NCT00876018
- Testing
- Nutritional supplement
- Where
- India
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Attention Deficit Hyperactivity Disorder (ADHD)
Micronutrient Supplementation and Chronotherapy in Children With ADHD
Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental condition in children that can affect attention, behavior, learning, and daily functioning.
- Trial name
- SMART-ADHD (NCT07922252)
- Testing
- Broad-spectrum multivitamin and mineral supplementation, Chronotherapy-Based Lifestyle Guidance
- Where
- Malaysia
- Volunteers
- 120 people
- Sponsor
- UCSI University
Malnutrition
Comparison of the Effect of Two Treatments on the Nutritional and Micronutrient Status of Malnourished Children
The purpose of this study is to measure the impact of a fortified food on the nutritional and micronutrient status of malnourished children, compared with milk.
- Trial name
- NCT01643187
- Testing
- Beverage fortified with 21 vitamins and minerals, Lactose-free milk
- Where
- Guatemala
- Volunteers
- 1,000 people
- Sponsor
- Association for the Study and Prevention of HIV/AIDS
Diabetes Mellitus, Type 1, Diabetes Mellitus
Diamyd Administered Into Lymph Nodes in Combination With Vitamin D in Type 1 Diabetes
The objective of DIAGNODE-2 is to evaluate the efficacy of Diamyd compared to Placebo, upon administration directly into a lymph node in combination with an oral vitamin D/Placebo regimen, in terms of preserving endogenous…
- Conditions
- Diabetes Mellitus, Type 1, Diabetes Mellitus, Autoimmune Diseases, Metabolic Disease
- Trial name
- NCT03345004
- Testing
- Diamyd, Vitamin D
- Where
- 18 sites in Czechia, Netherlands and 2 more
- Volunteers
- 109 people
- Sponsor
- Diamyd Medical AB
Malnutrition
Acceptability of Zinc-fortified Lipid-based Nutrient Supplements
The purpose of the study is to assess the acceptability of the two lipid-based nutrient supplement (LNS) formulations containing no zinc and a high amount of zinc (10 mg zinc / 20 g dose of LNS).
- Trial name
- NCT00944814
- Testing
- LNS with zinc, LNS without zinc
- Where
- Burkina Faso
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Malnutrition
Effect of Home-fortification With Sprinkles in Hematologic and Nutritional Status in Preschool Children in Medellín
Objective: To acquire the local scientific evidence, to evaluate the effects of micronutrient Sprinkles™ powder, both the nutritional status and haematological values in the vulnerable preschool population, to corroborate the…
- Trial name
- NCT01917032
- Testing
- Sachets containing a blend of micronutrients in powder form (Iron, Zinc, Folic Acid, Vitamin A and C), sprinkled onto home made food
- Where
- Colombia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- CES University
Anemia
Monitoring and Evaluation of Micronutrients (Sprinkles) Project
The purpose of this study is 1) to evaluate the effectiveness in reducing anemia among children 6-24 months of age by providing daily micronutrient Sprinkles through the Government of Pakistan's Lady Health Worker program; 2) to…
- Trial name
- Sprinkles (NCT00659061)
- Testing
- SPRINKLES, Nutrition education
- Where
- Pakistan
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Child Nutrition Disorders
Effect of Behavior Change Communication About Improved Micronutrient Intake on Nutritional Status and Academic Performance of School Age Children in Meskan District, Gurage Zone, South Ethiopia
A cluster randomized controlled trial was chosen to exploit the robustness of this design to help ascertain the efficacy of the BCC intervention compared to the routine dietary practice.
- Trial name
- BCC (NCT02956941)
- Testing
- BCC on Essential Nutrition and Hygiene Actions (ENHAs)
- Where
- Ethiopia
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- Jimma University
Pregnancy, Birth Weight
Prenatal Multi-micronutrient Supplementation and Pregnancy Outcome
Prenatal maternal micronutrient supplementation has been suggested as a means to reduce the proportion of low birth weight babies in low-income countries.
- Trial name
- NCT00168688
- Testing
- multi micronutrient supplement, MN1, MN2
- Where
- Guinea-Bissau
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- Bandim Health Project
Vitamin A Deficiency, Iron-deficiency
Effect of Household Use of Multiple Micronutrient-fortified Bouillon on Micronutrient Status Among Women and Children in Two Districts in the Northern Region of Ghana
Background: Micronutrient (MN) deficiencies are severe and widespread in West Africa, particularly among young children and women of reproductive age.
- Conditions
- Vitamin A Deficiency, Iron-deficiency, Folate Deficiency, Vitamin B 12 Deficiency
- Trial name
- NCT05178407
- Testing
- Multiple micronutrient-fortified bouillon cube, Control bouillon cube (iodine-only)
- Where
- Ghana
- Volunteers
- 2,372 people
- Sponsor
- University of California, Davis
Anemia
School-Based Assessment of Micronutrient Interventions in Adolescents in Burkina Faso
This purpose of this study is to assess effects of iron and folic acid supplementation and multiple micronutrient supplementation on anemia status, school performance/attendance and development outcomes among adolescents in…
- Trial name
- SAMIA (NCT04657640)
- Testing
- Iron and folic acid (IFA), Multiple Micronutrient Supplements (MMS) and loading dose of Iron and Folic Acid (IFA)
- Where
- Burkina Faso
- Volunteers
- 3,123 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Vitamin A Deficiency, Low Serum Retinol
Efficacy of β-carotene Biofortified Maize in Reducing Vitamin A Deficiency Among Children
The purpose of this cluster-randomized trial is to examine whether daily consumption of β-carotene biofortified maize flour can reduce the prevalence of vitamin A deficiency and improve the vitamin A status and among 4-8 year old…
- Trial name
- NCT01695148
- Testing
- β-Carotene Biofortified Maize Flour, White Maize Flour
- Where
- Zambia
- Volunteers
- 1,228 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Iron Deficiency Anaemia, Stunting
Zambia Micronutrient Powder Trial Effectiveness Study
Addressing micronutrient deficiencies in Zambia is recognized as a national priority by the government due to its major contribution to morbidity and mortality among children, especially infants in their formative years.
- Trial name
- NCT01878734
- Testing
- Micronutrient Powders
- Where
- Zambia
- Volunteers
- 631 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Anemia
Action Against Malnutrition Through Agriculture (AAMA) Plus MNP Study
Helen Keller International (HKI), the ministry of health and population, and ministry of agriculture and cooperatives, of Nepal and local non-governmental organizations (NGO) partners are currently implementing a USAID funded…
- Trial name
- MNP (NCT01488305)
- Testing
- MNP (micro-nutrient powders), AAMA project activities (HFP and IYCF BCC)
- Where
- Nepal
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Helen Keller International
Overweight and Obesity, Stunted Growth
Intervention in Children With Malnutrition
Malnutrition is an epidemiologic problem with high prevalence in Mexico. Mexican children present a double burden of malnutrition characterized by the coexistence of undernutrition and micronutrient deficiency alongside excess…
- Conditions
- Overweight and Obesity, Stunted Growth, Malnutrition, Child, Nutrient Deficiency
- Trial name
- NCT04915638
- Testing
- Experimental intervention group with enriched cookies
- Where
- Mexico
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Marta Alicia Menjivar Iraheta
Pregnancy, Adherence
A Study of Multiple Micronutrient Supplementation (MMS) to Increase Adherence With Digital Technology
The goal of this randomized clinical trial is to learn whether a digital health intervention can improve adherence to Multiple Micronutrient Supplementation (MMS) among pregnant women in Lombok Island.
- Trial name
- SMART-MMS (NCT07555093)
- Testing
- Bottle pack, Blister pack, Standard Care
- Where
- Indonesia
- Volunteers
- 10,012 people, healthy volunteers welcome
- Sponsor
- Summit Institute for Development, Indonesia