Clinical trials: Middle-aged and Older Adults
Pain, Otitis Media
Study of FAECC Scale (Modified FLACC) to Evaluate Ear Pain in Children With Acute Otitis Media
This study is to assess the reliability and validity of the FAECC scale to evaluate pain associated with acute otitis media in children aged 2 months to 5 years.
- Trial name
- NCT01588535
- Testing
- benzocaine
- Where
- 15 sites in United States
- Volunteers
- 38 people
- Sponsor
- Arbor Pharmaceuticals, Inc.
Anxiety, Depression
Evaluating Knowledge Insight Tools (KIT) for Reducing Anxiety and Low Mood in UK Secondary School Students
Background and Study Aims: Secondary school students are reporting unprecedented levels of anxiety and mood difficulties. To ensure that the needs of all young people are met, there is a need to evaluate more accessible forms of…
- Conditions
- Anxiety, Depression, Internalizing Problems, Low Mood
- Trial name
- NCT06188962
- Testing
- CBT-informed school-based counselling
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- University College, London
Acute Otitis Media
Phase 3 Study to Compare the Efficacy and Safety of AR01 to a Placebo Solution for Relief of Pain in Acute Otitis Media
Children ages 2 months to less than 19 years old, who have been diagnosed with a middle ear infection may receive either medicated ear drops (AR01) or glycerin (placebo) ear drops.
- Trial name
- AR01006 (NCT02044341)
- Testing
- AR01, Glycerin ear drops
- Where
- 29 sites in United States
- Volunteers
- 304 people
- Sponsor
- Arbor Pharmaceuticals, Inc.
Infant Sleep and Crying
Effects of Two Swaddling Techniques on Infant Sleep, Crying, and Maternal Comfort
The goal of this clinical trial is to learn how two different safe swaddling techniques affect sleep duration, crying duration, and maternal comfort in infants aged 1-4 months and their mothers.
- Trial name
- NCT07868380
- Testing
- Hip-Healthy Swaddling, Midline Flexion Swaddling
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Izmir University of Economics
Anaplastic Thyroid Cancer, Insular Thyroid Cancer
Gefitinib in Treating Patients With Metastatic or Unresectable Head and Neck Cancer or Non-Small Cell Lung Cancer
This phase I trial is studying the side effects of gefitinib in treating patients with metastatic or unresectable head and neck cancer or non-small cell lung cancer.
- Conditions
- Anaplastic Thyroid Cancer, Insular Thyroid Cancer, Metastatic Parathyroid Cancer, Recurrent Adenoid Cystic Carcinoma of the Oral Cavity
- Trial name
- NCT00068497
- Testing
- gefitinib
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Cancer Institute (NCI)
Osteoarthritis of the Knee
Structured Treatment of Osteoarthritis of the Knee With or Without Total Knee Replacement
The purpose of this study is to test whether surgical insertion of total knee replacement provides further improvement in quality of life, pain and function in addition to an algorithm for systematic non-surgical treatment…
- Trial name
- MEDIC (NCT01410409)
- Testing
- Neuromuscular training (NEMEX-TJR), Paracetamol, Burana
- Where
- 3 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Acute Otitis Media
Study to Compare Efficacy and Safety of AR01 to a Placebo Solution for Relief of Pain in Acute Otitis Media (AR01007)
Children ages 2 months to less than 19 years old, who have been diagnosed with a middle ear infection may receive either medicated ear drops (AR01) or glycerin (placebo) ear drops.
- Trial name
- NCT02074007
- Testing
- AR01
- Where
- 21 sites in United States
- Volunteers
- 178 people
- Sponsor
- Arbor Pharmaceuticals, Inc.
Substance Use, Parenting
Feasibility Study of a Web-based Program to Help Parents of Middle School Students Effectively Communicate With Their Children About Substance Use
The goal of this study is to test the feasibility of a web-based program for parents of middle school aged students. 286 parents and their child in 6th, 7th, or 8th grade will be asked to each complete two online questionnaires…
- Conditions
- Substance Use, Parenting, Communication
- Trial name
- NCT05900115
- Testing
- Media Ready Parent, Active Control Program
- Where
- United States
- Volunteers
- 576 people, healthy volunteers welcome
- Sponsor
- Innovation Research & Training
General Population of Children Aged 3 to 5 Years Old
Early Development of Academic Skills in the Classroom
This is a two-arm cluster randomized controlled trial. The two arms will be: 1) Intervention group, where the stimulation program will be implemented; and 2) Comparison group (active).
- Trial name
- JAPI (NCT05224700)
- Testing
- JAPI, Painting group
- Volunteers
- 754 people, healthy volunteers welcome
- Sponsor
- University of Talca
Healthy, Physical Examination
Walking Aid Assessment, Arm Strength and Force Under the Foot in Normal Subjects
This study will collect biomedical performance data on walking characteristics in normal, healthy people when walking with walking aids and when walking unaided.
- Conditions
- Healthy, Physical Examination, Middle Age, Aged
- Trial name
- NCT05092932
- Testing
- Normal Foot Force
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Saskatchewan
Dementia
IDEA Study Cognitive Stimulation Therapy (CST) Trial in Tanzania
This trials of cognitive stimulation therapy (CST) in Tanzania is part of the larger Identification and Intervention for Dementia in Elderly Africans (IDEA) study.
- Trial name
- IDEA (NCT02229474)
- Testing
- CST Intervention
- Where
- Tanzania
- Volunteers
- 34 people
- Sponsor
- William Keith Gray
Dementia
IDEA Study Cognitive Stimulation Therapy (CST) Trial in Nigeria
This trials of cognitive stimulation therapy (CST) in Tanzania is part of the larger Identification and Intervention for Dementia in Elderly Africans (IDEA) study.
- Trial name
- IDEA (NCT02233530)
- Testing
- CST intervention
- Where
- Nigeria
- Volunteers
- 8 people
- Sponsor
- William Keith Gray
Fractures, Bone, Fragility
Factors Associated With Future Fractures in Middle-aged Men and Women
From prospectively collected health and life-style data and anthropometric data in the Malmo Diet and Cancer (MDC) cohort identify factors that predicts or are associated with forthcoming fracture in middle-aged men and women.
- Conditions
- Fractures, Bone, Fragility, Life Style
- Trial name
- MDCFract (NCT04151732)
- Testing
- Physical activity, alcohol, tobacco, Hormonal factors, Cardiovascular disease
- Where
- Sweden
- Volunteers
- 30,351 people, healthy volunteers welcome
- Sponsor
- Lund University
Nutrition, Healthy
Total Energy Expenditure Across the Life Course in Low-and Middle-Income Countries -- Chinese Children
By 2050, there will be 9 billion people on earth. It will be necessary to feed them to avoid the population catastrophe predicted by Malthus 150 years ago.
- Trial name
- NCT07054294
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences
Reading Problem
Computer Based Newsletter and Literacy Engagement of Middle-school Students
The purpose of this study is to improve motivation for reading by implementing a computer-based newsletter and examine the effects on the literacy engagement and reading achievement of middle school-aged students.
- Trial name
- NCT04511065
- Testing
- Newsletter using a virtual mode of delivery
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Stunting, Thinness
The Double Burden of Malnutrition Among Adolescents in Low-income and Middle-income Countries
Individual-participant data analysis of the Global School-Based Student Health Survey and Health Behaviour in School-Aged Children surveys in 57 LMICs between 2003-2013.
- Conditions
- Stunting, Thinness, Obese
- Trial name
- NCT03346473
- Volunteers
- 129,276 people, healthy volunteers welcome
- Sponsor
- University of Warwick