Clinical trials: Minimally Invasive Treatment
Prostate Cancer, Bladder Outlet Obstruction
Prostatic Artery Embolization in Advanced Prostate Cancer
This is a pilot study assessing efficacy and safety in patients with advanced prostate cancer.
- Trial name
- NCT03457805
- Testing
- Prostatic Artery Embolization
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Dominik Abt
Hepatocellular Carcinoma
The AI Prognostic Assessment and Pathological Basis Research of Early HCC After Minimally Invasive Treatment
The study evaluates artificial intelligence method based on multimodal magnetic resonance imaging (MRI) images and clinical data in preoperative prediction of prognosis in early hepatocellular carcinoma (HCC) patients treated…
- Trial name
- NCT04299919
- Testing
- Minimally invasive treatment, Hepatectomy
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- The First Affiliated Hospital of Dalian Medical University
Dental Caries
Building Adaptive School-based Interventions for Caries
Dental caries (tooth decay) is the world's most prevalent noncommunicable disease. Current preventive and therapeutic treatments are available that can be provided in a school-based health service environment.
- Trial name
- BASICS (NCT07265830)
- Testing
- Silver Diamine Fluoride (38%), Glass Ionomer Sealant, Fluoride Varnishes
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Superior Mesenteric Artery Syndrome, Duodenal Obstruction
Comparison of One Anastomisis Gastric Bypass and Duodeno-Jejunostomy for Treating SMA Syndrome
The goal of this clinical trial is to find out which surgery works better to treat people with a rare condition called Superior Mesenteric Artery Syndrome (SMAS).
- Conditions
- Superior Mesenteric Artery Syndrome, Duodenal Obstruction, Weight Loss, Gastrointestinal Disease
- Trial name
- NCT06970093
- Testing
- One Anastomosis Gastric Bypass, Duodenojejunostomy
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Ain Shams University
Molar Incisor Hypomineralization
Clinical Evaluation of Resin Infiltration Treatment of MIH-affected Teeth in Pediatric Patients
The goal of this clinical trial is to examine the clinical success of different pre-treatments in resin infiltration therapy applied to the incisors of pediatric patients with Molar Incisor Hypomineralization (MIH) and to…
- Trial name
- NCT07469124
- Testing
- Resin Infiltration, Microabrasion Followed by Resin Infiltration, Air Abrasion Followed by Resin Infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Inonu University
NRDS
Impact of Delayed Cord Clamping and Minimally Invasive Surfactant Administration on Outcomes in Premature Infants Less Than 30 Weeks Gestation
Background: Preventing early exposure to invasive mechanical ventilation in premature infants is crucial for reducing the incidence of bronchopulmonary dysplasia (BPD) and improving overall outcomes.
- Trial name
- NCT07092319
- Testing
- deferred cord clamping
- Where
- China
- Volunteers
- 518 people
- Sponsor
- Peking University Third Hospital
Respiratory Distress Syndrome, Newborn, Respiratory Distress Syndrome in Premature Infant
Utilization of Lung Ultrasound Score in Decision for Minimally Invasive Surfactant Administration
This prospective randomized controlled study aims to determine if using a lung ultrasound score can lead to a faster diagnosis of severe respiratory distress syndrome and quicker administration of surfactant in moderately and…
- Trial name
- NCT07442669
- Testing
- Lung ultrasound
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Hackensack Meridian Health
Initial Caries, Arrested Dental Caries
Early Caries Lesion Management Observational Study
The purpose of this observational study is to assess the effectiveness of Curodont Repair Fluoride Plus (CRFP) compared to other tooth-specific treatments (silver diamine fluoride (SDF), sealants, or other FDA-approved…
- Conditions
- Initial Caries, Arrested Dental Caries, Cavitated Caries, Dental Caries
- Trial name
- ELMO (NCT04933331)
- Testing
- Curodont Repair Fluoride Plus, Silver Diamine Fluoride, Glass Ionomer Sealant
- Where
- 4 sites in United States
- Volunteers
- 744 people, healthy volunteers welcome
- Sponsor
- CareQuest Institute for Oral Health
Parotitis, Juvenile Recurrent
Treatment of Juvenile Recurrent Parotitis: the Yield of Minimally Invasive Intervention
Juvenile recurrent parotitis (JRP) is an inflammatory disease characterized by recurrent painful swelling of the Parotid gland in the pediatric age.
- Trial name
- JRP (NCT04074694)
- Testing
- Sialoendoscopy
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Carmel Medical Center
Premature Birth, Respiratory Distress Syndrome
Comparison of the Results of Transcutaneous Carbon Dioxide and Oxygen Pressure in Premature Neonates Who Underwent MIST Under HHHFNC or Nasal CPAP Methods
Intratracheal surfactant treatment is applied in Respiratory Distress Syndrome (RDS) Continious Positive Airway Pressure(CPAP) treatment.
- Conditions
- Premature Birth, Respiratory Distress Syndrome, Surfactant Deficiency Syndrome Neonatal
- Trial name
- TCOPHC (NCT04505176)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Hacettepe University
Minimal Invasive Surfactant Administration in Two Different Non-invasive Ventilation Modes to NRDS Infants
NIV-MISA-NRDS Trial: a Multicenter Study in China
BACKGROUND Non-invasive ventilation (NIV) treatment have been developed to minimize lung damage and to avoid invasive mechanical ventilation (IMV) in preterm infants, especially in those with gestational age less than 30 weeks.
- Trial name
- NCT05137340
- Testing
- Nasal continuous positive airway pressure, Non-invasive positive pressure ventilation
- Where
- China
- Volunteers
- 312 people
- Sponsor
- Peking University Third Hospital
Hernia, Ventral, Rectus Diastasis
Endoscopic eTEP Versus Open Rives-Stoppa
Observational cohort study (partially retrospective, partially prospective) comparing the endoscopic extended totally extraperitoneal prosthesis (eTEP) repair for midline abdominal hernias to open Rives-Stoppa repair (control).
- Trial name
- NCT05446675
- Testing
- Endoscopic eTEP, Open Rives-Stoppa
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- AZ Alma
Molar Incisor Hypomineralisation, Enamel Hypomineralization
Comparison of Two Minimally Invasive Approaches for Masking Molar-Incisor Hypomineralization Opacities
This clinical study aimed to compare the effectiveness of two minimally invasive approaches for masking molar-incisor hypomineralization (MIH) opacities and to evaluate esthetic perceptions of children and their parents.
- Conditions
- Molar Incisor Hypomineralisation, Enamel Hypomineralization, Tooth Discoloration
- Trial name
- NCT07494682
- Testing
- Resin infiltration, Etch Bleach Seal Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Molar Incisor Hypomineralization
Minimally Invasive Treatment for Permanent Molars Affected With Molar-incisor Hypomineralization Defects
In this prospective randomized clinical trial, the is aim to compare the clinical and radiographic success of 3 minimally invasive treatment protocols on permanent first molars affected with MIH over 24 months.
- Trial name
- NCT05748067
- Testing
- SDF, HVGIC restoration, SSC
- Where
- Jordan
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Furcation Defects, Open Flap Debridement
Evaluation of Outcomes of Minimally Invasive Non- Surgical Versus Surgical Therapy in Furcation Involvement.
The reduced rate of success experienced in the treatment of Furcation involvement (FI) seems to result from the incomplete removal of subgingival plaque and calculus in the interradicular area owing to the peculiar anatomy of the…
- Conditions
- Furcation Defects, Open Flap Debridement, Periodontal Diseases
- Trial name
- NCT06025955
- Testing
- minimally invasive non- surgical therapy, open flap debridement
- Where
- India
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Venous Malformations, Arteriovenous Malformations
Microwave Ablation for Treatment of Vascular Malformations: Efficacy and Safety
This clinical trial aims to assess the safety and efficacy of microwave ablation in treating vascular malformations, including both venous malformations (VM) and arteriovenous malformations (AVM).
- Conditions
- Venous Malformations, Arteriovenous Malformations, Microwave Ablation, Vascular Malformations
- Trial name
- NCT07404670
- Testing
- Microwave Ablation
- Volunteers
- 150 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Respiratory Distress Syndrome
Early CPAP And Large Volume Minimally Invasive Surfactant (ECALMIST) in Preterm Infants With RDS
Modification of Minimally Invasive Surfactant Therapy (MIST) to a new technique called ECALMIST (Early CPAP And Large volume Minimal Invasive Surfactant).
- Trial name
- ECALMIST (NCT01553292)
- Testing
- ECALMIST
- Where
- 3 sites in Canada
- Volunteers
- 21 people
- Sponsor
- University of Manitoba
Abnormal Uterine Bleeding
Patient Satisfaction With Initial Phone Call Versus Office Visit Following Minimally Invasive Hysterectomy, a Randomized Controlled Trial.
Patients will be randomized to clinic or telephone follow up after outpatient TLH. surveys will document patient satisfaction.
- Trial name
- NCT03809468
- Testing
- phone call follow up
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic