Clinical trials: Misoprostol
Induction of Labour
REgistry of MisOprostol 200 µg Vaginal dElivery System
The design of the study is post-marketing, observational, multi-centre and open-label. The study does not provide treatment; only patients to whom misoprostol 200 µg vaginal delivery system (VDS) is prescribed may be included.
- Trial name
- REMOVE (NCT02242214)
- Testing
- Misoprostol
- Where
- Netherlands
- Volunteers
- 106 people
- Sponsor
- Ferring Pharmaceuticals
Cervical Ripening and Induction of Labor
Cervical Ripening: A Comparison Between Intravaginal Misoprostol Tablet and Intracervical Foley's Catheter and Subsequent Induction of Labor, Safety and Efficacy in Federal Teaching Hospital Abakaliki, Ebonyi State, Nigeria.
The aim of this study is to compare the effectiveness and safety of Foley's catheter and misoprostol in cervical ripening.
- Trial name
- NCT02574338
- Testing
- Foley's Catheter, prostaglandin E1 analogue
- Where
- Nigeria
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Nwali Matthew Igwe
Induced Abortion, First Trimester Abortion
Study of Clinic-based vs. Self-use of a Misoprostol-only Regimen for Induced Abortion
The goal of the study is to determine whether important clinical outcomes differ among women who access a misoprostol-only medication abortion regimen from a patent medicine vendor when compared with those who access it from a…
- Trial name
- NCT04242212
- Testing
- Misoprostol sourced from clinics, Misoprostol sourced from PMVs
- Where
- 3 sites in Nigeria
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Ipas
Premature Rupture of Membranes at Term
Comparison of Misoprostol and Prostaglandin E2 (PGE2) Gel for Induction of Labour in Premature Rupture of Membranes at Term
The purpose of this study is to determine whether induction of labor with vaginal misoprostol application will result in fewer cesarean deliveries than vaginal PGE2 gel application in women with premature rupture of membranes at…
- Trial name
- NCT00355303
- Testing
- Misoprostol, PGE2 gel
- Where
- India
- Volunteers
- 932 people
- Sponsor
- Nilratan Sircar Medical College
To Compare Efficacy Intrauterine vs Sublingual MISOPROSTOL in Addition to Oxytocin in Reducing Blood Loss of Post-cesarean Section in High Risk Women
Sublingual vs Intrauterine MISOPROSTOL Plus Oxytocin Infusion for Prevention of Post-cesarean Hemorrhage in High Risk Pregnant Women: A Double-blind Placebo RCT
Research Objective: Primary outcome -To compare efficacy Intrauterine vs Sublingual MISOPROSTOL in addition to Oxytocin in reducing blood loss of post-cesarean section in high risk women Secondary outcome -To study…
- Trial name
- NCT04560218
- Testing
- sublingual Misoprostol, Intrauterine Misoprostol
- Where
- Thailand
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Postpartum Hemorrhage
Comparing Misoprostol and Oxytocin in UnijectTM for Postpartum Hemorrhage (PPH) Prevention in Mali
This is a large, community-based, cluster-randomized trial to compare routine prophylactic use of 600 mcg oral misoprostol and 10 IU oxytocin delivered by UnijectTM intramuscularly during the third stage of labor.
- Trial name
- NCT01487278
- Testing
- misprostol, UnijectTM
- Where
- Mali
- Volunteers
- healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Legally Induced Abortion Without Mention of Complication
A Comparison of Sublingual and Buccal Misoprostol Regimens After Mifepristone for Mid-trimester Abortion
The primary goal of this study is to directly compare repeat doses of sublingual and buccal routes of 400 mcg misoprostol following mifepristone for second trimester abortion in order to determine if sublingual route confers an…
- Trial name
- NCT02708446
- Testing
- Mifepristone, Buccal misoprostol, Sublingual misoprostol
- Where
- 4 sites in Armenia, Nepal and 2 more
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Induction of Labor
Sublingual Versus Vaginal Misoprostol for Labor Induction at Term
Misoprostol (Cytotec®) is a synthetic prostaglandin E1 analog that has been marketed in the United States since 1988 as a gastric cytoprotective agent.
- Trial name
- NCT00140114
- Testing
- Misoprostol (Cytotec®)
- Where
- Lebanon
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Abortion, Induced
Mifepristone and Misoprostol Versus Misoprostol Alone for Mid-trimester Termination of Pregnancy (14 - 21 Weeks LMP): A Randomized-controlled Double-blinded Trial
The primary goal of this study is to determine the clinical advantage of pre-treatment with mifepristone in second trimester misoprostol induction abortion.
- Trial name
- NCT00784186
- Testing
- mifepristone+misoprostol, misoprostol
- Where
- 2 sites in Vietnam
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Induction of Labour, Labour, Induced
Misoprostol Labour Induction Study
Labour induction is a frequent obstetric intervention (~20%). Prostaglandins (PGs) are effective agents, but gastrointestinal (GI) intolerance has limited use to non-oral routes.
- Trial name
- NCT03489928
- Testing
- Oral Misoprostol, Vaginal Misoprostol, Dinoprostone
- Volunteers
- 511 people, healthy volunteers welcome
- Sponsor
- David Young
Myomectomy
Tranexamic Acid Versus Vaginal Misoprostol in Abdominal Myomectomy
the aim of the present study is to evaluate safety and efficacy of tranexamic acid versus vaginal misoprostol in reducing intraoperative blood loss during abdominal myomectomy
- Trial name
- NCT04358965
- Testing
- intravenous tranexamic acid, vaginal misoprostol
- Volunteers
- 162 people
- Sponsor
- Cairo University
Labor, Induced
Sublingual Misoprostol for Induction of Labor
The purpose of this study is to compare effectiveness and safety of a sublingual misoprostol 12,5 mcg with vaginal misoprostol 25 mcg for induction of labour with an alive and term fetus.
- Trial name
- SUBMISO (NCT01406392)
- Testing
- Misoprostol 25mcg, Sublingual Misoprostol
- Where
- Brazil
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Professor Fernando Figueira Integral Medicine Institute
Labor Augmentation
A Trial of Oral Misoprostol for Labor Augmentation
This is a prospective, randomized, controlled trial designed to examine the efficacy of oral misoprostol for labor augmentation compared to a standard regimen of intravenous oxytocin.
- Trial name
- NCT00906347
- Testing
- Misoprostol, Oxytocin
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Incomplete Abortion
Misoprostol Treatment of Mid Trimester Incomplete Abortion by Midwives and Doctors in Uganda.
It is estimated that 47,000 women die every year due to consequences of unsafe abortion globally. The majority of pregnancy related deaths occur in low income countries where induced abortion is restricted, unmet need for…
- Trial name
- NCT03622073
- Testing
- Misoprostol treatment by Midwife, Misoprostol treatment by Doctor
- Where
- 14 sites in Uganda
- Volunteers
- 1,191 people
- Sponsor
- Makerere University
Postpartum Hemorrhage
Buccal Misoprostol During Cesarean Section for Preventing Postpartum Hemorrhage
Objective: to demonstrate that buccal misoprostol administration during cesarean delivery in women with risk factors for uterine atony decreases the need for additional uterotonic medications, uterine atony and postpartum…
- Trial name
- NCT01733329
- Testing
- Misoprostol, Folic Acid
- Where
- Mexico
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Contraception
Comparative Efficacy of Lidocaine Spray Versus Vaginal Misoprostol in IUD Insertion
the aim of the present study is to compare the safety and efficacy of lidocaine spray versus misoprostol in reducing pain during IUD insertion in adolescents and nulliparous women
- Trial name
- NCT04339049
- Testing
- lidocaine spray, vaginal misoprostol
- Where
- Egypt
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post Partum Hemorrhage
Sublingual Misoprostol in Reduction of Caesarean Blood Loss
Caesarean delivery is inevitably associated with a higher amount of blood loss vis-à-vis primary postpartum haemorrhage, when compared to vaginal delivery.
- Trial name
- SUMIROCBLOL (NCT05532215)
- Testing
- Misoprostol, Oxytocin
- Where
- Nigeria
- Volunteers
- 152 people
- Sponsor
- OZORI EBIOGBO STANLEY
Postpartum Hemorrhage
Misoprostol for Secondary Prevention of Postpartum Hemorrhage at the Community Level in India
This study compares two community-level strategies: selective administration of 800 mcg sublingual misoprostol to women at 350 mL blood loss for secondary prevention of postpartum hemorrhage (PPH) with universal use of 600 mcg…
- Trial name
- NCT01462422
- Testing
- Misoprostol
- Where
- India
- Volunteers
- 3,032 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Abortion, Therapeutic
A Randomized Study of Cervical Priming With Misoprostol Prior to Elective First Trimester Pregnancy Termination
The purpose of this study is to determine whether misoprostol administered prior to elective first trimester pregnancy has an effect on pain and ease of procedure and complications.
- Trial name
- NCT00310921
- Testing
- Misoprostol
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Labor Induction
A Randomized Trial of Two Regimens of Misoprostol for Second Trimester Termination for Intrauterine Fetal Death
Misoprostol (Cytotec®) is a synthetic prostaglandin E1 analog that has been marketed in the United States since 1988 as a gastric cytoprotective agent.
- Trial name
- NCT00141895
- Testing
- Misoprostol
- Where
- Lebanon
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center