Clinical trials: Mode of Therapy
Small Cell Lung Cancer
Transformation Into Small Cell Lung Cancer : a Mode of Resistance to Treatment
The discovery of oncogenic mutations and the use of targeted therapies have transformed the management of certain tumors. Thus 12 to 15% of bronchial adenocarcinomas (AD) carry mutations of EGFR and receive from the first line…
- Trial name
- TransCPC (NCT03419286)
- Volunteers
- 62 people
- Sponsor
- University Hospital, Grenoble
Lice; Head Lice
Efficacy and Safetyof a Medical Device With a Physical Mode of Action (X92001919) Versus Paranix Anti-lice Shampoo.
Comparison of the efficacy of a new medical device with a physical mode of action to Paranix anti-lice shampoo in the treatment of head lice infestation.
- Trial name
- NCT07244523
- Testing
- Pulverize (X92001919)
- Volunteers
- 34 people
- Sponsor
- Oystershell NV
Post-stroke Cognitive Impairment
Noninvasive Dual-mode Stimulation Therapy for Neurorehabilitation in Post-stroke Cognitive Impairment
Repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS) has been used for the modulation of post-stroke cognitive impairment patients' cognitive function by altering the cortical…
- Trial name
- NCT03647319
- Testing
- High-frequency rTMS on left DLPFC+anodal tDCS on right DLPFC, High-frequency rTMS on left DLPFC+cathodal tDCS on right DLPFC
- Where
- South Korea
- Volunteers
- 29 people
- Sponsor
- Samsung Medical Center
Assess the Benefits From the AAISafeR/SafeR Algorithm of Symphony 2550 or REPLYTM DR in a Wide Range of Pacemaker Patients.
Evaluation of the SafeR Mode in Patients With a Dual Chamber Pacemaker Indication
The aim of this study is to assess the benefits from the AAISafeR/SafeR algorithm of Symphony 2550 or REPLY DR in a wide range of pacemaker patients.
- Trial name
- ANSWER (NCT00562107)
- Testing
- Symphony DR 2550 and REPLY DR cardiac pacemakers
- Where
- 37 sites in United States, France and 4 more
- Volunteers
- 650 people
- Sponsor
- LivaNova
Major Depressive Disorder, Mood Disorders
Mechanisms of Rumination Change in Adolescent Depression
This study will evaluate whether a newer treatment, rumination-focused cognitive behavioral treatment, which includes mindfulness and can be used to reduce ruminative habits, change ways in which key brain regions interact with…
- Trial name
- RuMeChange (NCT03859297)
- Testing
- Rumination-Focused CBT, Relaxation-based Therapy
- Where
- 3 sites in United States
- Volunteers
- 183 people
- Sponsor
- Ohio State University
Bone and Soft Tissue Tumors, Clinical Features
Study on Clinical Features, Treatment Mode and Survival of Bone and Soft Tissue Tumors
It is planned to prospectively collect, collate and report real-world clinical data of BSTS patients treated in our hospital in the next ten years to evaluate the changes in clinical characteristics, treatment patterns and…
- Trial name
- NCT05468970
- Testing
- NO Intervention
- Where
- China
- Volunteers
- 6,000 people
- Sponsor
- Henan Cancer Hospital
Fear of Childbirth
A Randomized Longitudinal Trial About Treatment for Severe Fear of Childbirth
Site of research: Helsinki University Central Hospital (HUCH), Department of Obstetrics and Gynaecology and University of Helsinki Department of Psychology, in collaboration with Karolinska University Hospital in Stockholm…
- Trial name
- LINNEA (NCT01548131)
- Testing
- Psychoeducative group therapy
- Where
- Finland
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Sarcoma
Study on Clinical Features, Treatment Mode and Survival of Sarcoma
The clinical data of all eligible patients who received chemotherapy, radiotherapy, targeted therapy, immunotherapy, interventional therapy and surgery in Henan Tumor Hospital from June 1, 2012 to May 30, 2022 were…
- Trial name
- NCT05453409
- Testing
- No intervention
- Where
- China
- Volunteers
- 6,000 people
- Sponsor
- Henan Cancer Hospital
Type1diabetes
Assessment of Two Insulin Pump Insulin Delivery Systems in Type 1 Diabetes.
This is a study of the Minimed 670G 4.0 insulin pump, assessing the efficacy of the Advanced Hybrid Closed Loop (AHCL) algorithm in controlling blood glucose levels in Type 1 Diabetes.
- Trial name
- NCT04073576
- Testing
- AHCL, SAP+PLGM
- Where
- New Zealand
- Volunteers
- 60 people
- Sponsor
- Christchurch Clinical Studies Trust Ltd
Acute Kidney Injury
The Optimal Mode of Renal Replacement Therapy in Acute Kidney Injury (OMAKI) Study
Acute kidney injury (AKI) in the intensive care unit is common, devastating and costly. However, minimal evidence exists to guide the prescription of optimal renal replacement therapy (RRT).
- Trial name
- OMAKI (NCT00675818)
- Testing
- Continuous venvenous hemofiltration (CVVH), Continuous venovenous hemodialysis (CVVHD)
- Where
- 5 sites in Canada
- Volunteers
- 78 people
- Sponsor
- Unity Health Toronto
Primary Immunodeficiency Diseases (PID)
Tolerability and Safety of IGI, 10% With rHuPH20 in PIDD
The purpose of the study is to acquire additional data on safety and tolerability of recombinant human hyaluronidase (rHuPH20) facilitated subcutaneous treatment of Immune Globulin Infusion (Human), 10% (IGI, 10%) and to assess…
- Trial name
- NCT01485796
- Testing
- Immune Globulin Infusion (Human), 10%, Recombinant human hyaluronidase
- Where
- 10 sites in United States
- Volunteers
- 54 people
- Sponsor
- Baxalta now part of Shire
Turner Syndrome, Hypogonadism
Estrogen Treatment (Oral vs. Patches) in Turner Syndrome
The study attempts to evaluate if the way of administering estrogen, the principal female hormone, via patches or orally, affects the way estrogen works in girls with Turner Syndrome.
- Conditions
- Turner Syndrome, Hypogonadism, Premature Ovarian Failure
- Trial name
- NCT00140998
- Testing
- 17 beta estradiol
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Nemours Children's Clinic
Myalgia, Trigger Point
Comparative Evaluation of Continuous and Pulse Mode of Ultrasound Therapy in Myalgia of Maxillofacial Region
Pain and trismus caused by Myalgia in masticatory muscles are one of the prime concerns for the patients. Various studies have been performed using US therapy for myofascial pain syndrome of head \& neck region.
- Trial name
- NCT05211245
- Testing
- therapeutic ultrasound
- Where
- India
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Pain
Is Paracetamol an Effective Treatment for Chronic Moderate Pain in the Newborn After Operative Vaginal Delivery?
There are many reasons for using a vacuum apparatus or forceps to assist in delivering a baby. The traction and pressure on the baby's head due to the vacuum apparatus or forceps may cause pain and discomfort for some time after…
- Trial name
- NCT00488540
- Testing
- Paracetamol
- Where
- 3 sites in Switzerland
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Speech Therapy, Language Disorders in Children
Pediatric Speech Therapy Session Frequency and Speech Outcomes
Examination of frequency of therapy and effect on clinical outcomes.
- Conditions
- Speech Therapy, Language Disorders in Children, Articulation Disorders in Children, Communication Disorder, Childhood
- Trial name
- NCT05900180
- Testing
- Speech Therapy
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Connecticut Children's Medical Center