Clinical trials: Moderate to Severe Dementia
Neurodegenerative Diseases, Behavioral Symptoms
Impact of Harp Therapy on Behavioral Disorders in Nursing Home Residents With Neurodegenerative Disease (ARPE)
The ARPE study looked at whether weekly harp therapy sessions could reduce behavioral problems in older adults living in memory care units of a nursing home (EHPAD).
- Conditions
- Neurodegenerative Diseases, Behavioral Symptoms, Dementia, Agitation
- Trial name
- ARPE (NCT07748013)
- Testing
- Harp therapy (receptive music therapy)
- Where
- France
- Volunteers
- 25 people
- Sponsor
- LNA SANTE
Breast Cancer, Chronic Myeloproliferative Disorders
Alemtuzumab and Glucocorticoids in Treating Newly Diagnosed Acute Graft-Versus-Host Disease in Patients Who Have Undergone a Donor Stem Cell Transplant
RATIONALE: Alemtuzumab and glucocorticoids, such as prednisone or methylprednisolone, may be an effective treatment for acute graft-versus-host disease caused by a donor stem cell transplant.
- Conditions
- Breast Cancer, Chronic Myeloproliferative Disorders, Gestational Trophoblastic Tumor, Graft Versus Host Disease
- Trial name
- NCT00410657
- Testing
- alemtuzumab, methylprednisolone, prednisone
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Fred Hutchinson Cancer Center
Moderate to Severe Dementia
Dementia Moves: Protocol for a Feasibility Study
Most long-term care (LTC) residents live with frailty and dementia and the proportion with more advanced cognitive impairment is increasing.
- Trial name
- NCT06400108
- Testing
- Dementia Moves
- Volunteers
- 16 people
- Sponsor
- Dalhousie University
Alzheimer Disease or Associated Disorder, Mild to Moderately Severe Dementia
Effectiveness of Care Management in Alzheimer Patients
Context: The French Alzheimer plan 2008-2012 includes the implementation of "disease managers" or social workers, from the onset of the disease, for every patient with a diagnosis of Alzheimer disease or associated disorder.
- Trial name
- AIDALZ (NCT01081743)
- Testing
- Intervention of the social worker
- Where
- France
- Volunteers
- 270 people
- Sponsor
- Institut de Sante Publique, d'Epidemiologie et de Developpement
Moderate to Severe Alzheimer's Disease
Donepezil and Memantine in Moderate to Severe Alzheimer's Disease
The trial will examine whether pharmacological treatment with donepezil, memantine or combination of memantine and donepezil is any better than a placebo (dummy) treatment in people with Alzheimer's disease who have reached the…
- Trial name
- DOMINO-AD (NCT00866060)
- Testing
- Memantine, Donepezil
- Where
- United Kingdom
- Volunteers
- 800 people
- Sponsor
- King's College London