Clinical trials: Monitoring, Intraoperative
Brain Neoplasms, Eloquent Area Brain Tumors
CONNEctome-guided Navigation for Eloquent-area Tumor Surgery Trial
This study is designed for patients with brain tumors located in eloquent brain areas involved in language, motor, or major functional brain networks.
- Trial name
- CONNECT Trail (NCT07657403)
- Testing
- Connectome-Guided Navigation-Assisted Microsurgical Resection, Conventional DTI Tractography-Guided Tumor Resection
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Craniosynostoses, Hypovolemia
Hemodynamic Monitoring During Craniosynostosis Surgery: Comparing Traditional and Newer Technology Monitors (CRASY-PRAM)
Hemodynamic evaluation during pediatric anesthesia is essential to care management. Intraoperative cardiovascular instability is frequent in major surgeries, and appropriate monitoring is necessary to ensure safe anesthetic…
- Conditions
- Craniosynostoses, Hypovolemia, Hemorrhage, Hemodynamic Instability
- Trial name
- CRASY-PRAM (NCT06263075)
- Testing
- Intraoperative monitoring
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Cerebral Oxygenation
Cerebral NIRS Monitoring During Anesthesia in Neonates and Infants
The brain is a very vulnerable organ, especially in premature babies, newborns and infants. However, during anesthesia, the oxygenation of the brain can only be monitored indirectly and insufficiently.
- Trial name
- NCT04132414
- Testing
- NIRS open
- Sponsor
- Medical University of Graz
Endocrine Procedural Complications, Thyroid
Intraoperative Monitoring to Predict Postoperative Complications After Thyroidectomy
The goal of this study is to evaluate the role of intraoperative continous and intermittent neuromonitoring and intraoperative parathormone (PTH) to predict postoperative nerve morbidity and hypocalcemia.
- Conditions
- Endocrine Procedural Complications, Thyroid, Parathyroid; Deficiency, Laryngeal Injury
- Trial name
- PARACAL (NCT03309384)
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Central Hospital, Nancy, France
Intraoperative Neurophysiological Monitoring, Pain Management
Effect of a Bolus of Clonidine Systemically Administered on the Excitability of the Spinal Motoneurons of the Lower Extremity
The purpose of this study is to assess the effect of IV clonidine administration on lower limb spinal motoneuron excitability during standardized total intravenous anesthesia (propofol and remifentanil).
- Trial name
- EXCICLON (NCT02592915)
- Testing
- Clonidine hydrochloride, Single bolus of physiologic sodium chloride serum administered IV after induction and obtaining a stable anaesthetic level
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Queen Fabiola Children's University Hospital
Spine Condition
Evaluating MIONM Effectiveness in Predicting Postoperative Neurological Deficits Using Combined Modalities
Objective: This study aimed to integrate findings from spinal and cranial surgeries with existing literature, emphasizing the role of Intraoperative Neurophysiological Monitoring (IONM) in improving surgical outcomes through best…
- Trial name
- MIONM (NCT06712069)
- Testing
- Multimodal Intraoperative Neurophysiologic Monitoring (MIONM)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Alexandria University
Masimo Radical Pulse Co-oximeter in Intraoperative Blood Transfusion Practice During Obestatric Procedure
The Value of Continuous Noninvasive Hemoglobin Monitoring Using Masimo Radical -7 Pulse CO-Oximeter in Intraoperative Blood Transfusion Practice During Obstetric Procedures
The principle aim of this study is to detect the accurracy of Masimo Radical-7¿ Pulse CO-Oximeter in relation to laboratory hemoglobin and estimated blood loss in intraoperative blood transfusion practice during obstetric…
- Trial name
- NCT03408938
- Testing
- of Masimo Radical-7¿ Pulse CO-Oximeter
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain, Monitoring, Intraoperative
Evaluation of the Pupil Dilation Reflex in Response to Noxious Stimulation in Anaesthetized Children. A Proof of Concept Trial
After conduction a pilot study, pupillary dilation reflex (PDR) is measured in response to nociceptive stimulation perioperatively in infants, children and adolescents.
- Trial name
- Pain@OR-kids (NCT03449732)
- Testing
- PDR measurement
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- University Hospital, Antwerp
Anesthesia, Monitoring, Intraoperative
Registry Construction of Intraoperative Vital Signs and Clinical Information in Surgical Patients
Monitoring data during anesthesia of surgical patient in the operation room will be collected and stored into the registry automatically. Patients' information and preoperative assessment from medical records will be included.
- Trial name
- NCT02914444
- Where
- South Korea
- Volunteers
- 200,000 people
- Sponsor
- Seoul National University Hospital
Humans, Urinary Incontinence
Intraoperative Nerve Monitoring During Robotic-assisted Radical Prostatectomy
The purpose of this study is to evaluate whether the use of intraoperative nerve monitoring during robotic-assisted radical prostatectomy (RARP) can predict and improve post-surgery urinary continence and erectile function.
- Conditions
- Humans, Urinary Incontinence, Male Urogenital Diseases, Prostatectomy
- Trial name
- NCT03721029
- Testing
- Intraoperative nerve monitoring,, standard of care robotic-assisted radical prostatectomy
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Herlev and Gentofte Hospital
Spine Injuries and Disorders
Evaluation Of Intra-Operative Neuro-Monitoring Alarm During Complex Spine Surgery
Iatrogenic spinal cord injury is the most feared complication of complex spine surgery. The incidence of neurological complications for spinal deformity surgery has been estimated by the Scoliosis Research Society as 1%, except…
- Trial name
- NCT05710016
- Volunteers
- 64 people
- Sponsor
- Assiut University
Bradycardia, Conduction Block, Atrioventricular
LLL vs. SDL for LBBP: A Non-inferiority RCT
Left Bundle Branch Pacing (LBBP) has emerged as one of the most commonly used physiological pacing modalities in clinical practice.
- Trial name
- NCT07378124
- Testing
- SDL implantation, LLL implantation
- Where
- China
- Volunteers
- 288 people
- Sponsor
- Ningbo No.2 Hospital
Anesthesia Complication, Surgical Blood Loss
Cerebral Oxygenation, Different Measurement Points and Their Correlation in Pediatric Population
Children who undergo surgery routinely for surgery that risk high levels of circulatory changes (eg heart surgery) is currently used routinely monitoring as regional oxygenation technology of the brain (NIRS).
- Trial name
- NCT03136952
- Testing
- NIRS frontal and occipital
- Where
- Sweden
- Volunteers
- 17 people
- Sponsor
- Göteborg University
Intraoperative Neurophysiological Monitoring, Complication
Patient Experiences of IONM and Outcomes
Resection of brain tumours forms a large proportion of work in brain surgery. One important aspect is to minimize damage to normal brain structures during this process. This improves patient outcomes and reduces complications.
- Conditions
- Intraoperative Neurophysiological Monitoring, Complication, Intraoperative Complications, Postoperative Complications
- Trial name
- IONM (NCT04443465)
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- King's College Hospital NHS Trust
Cardiovascular Diseases
Wearable Ultrasound for Cardiac Monitoring During Surgery and in Intensive Care
This study aims to evaluate the accuracy, feasibility, and clinical usefulness of a wearable ultrasound imaging system for cardiac monitoring during perioperative care and in intensive care units (ICUs).
- Trial name
- NCT07891052
- Testing
- Wearable Ultrasound Imaging System
- Volunteers
- 600 people
- Sponsor
- China National Center for Cardiovascular Diseases
Recurrent Laryngeal Nerve Injuries
CRANIO-CAUDAL AND LATERAL APPROACH FOR RECURRENT LARYNGEAL NERVE
The recurrent laryngeal nerve (RLN) dissection should be performed cranio-caudally in TOETVA approach.The aim of this study was to compare the cranio-caudal and lateral approach for RLN dissection in regard with the rates of LOS…
- Trial name
- NCT04379804
- Testing
- Lateral approach, Cranio-caudal approach
- Where
- Turkey (Türkiye)
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Anesthesia
Decision Support System for Anesthetists
The balanced anesthesia process contains three main parts: the control of hypnosis, analgesia, and neuromuscular blockade. For the induction phase, the anesthesiologist performs protocols based on prior planning specific to each…
- Trial name
- Serenity (NCT04079036)
- Where
- Brazil
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Anesthesia, Anesthesia Awareness
Pediatric Validation of CONOX Monitor During Surgery
Pediatric Validation of CONOX Monitoring device (qCON and qNOX indices) for anesthesia depth during surgery
- Conditions
- Anesthesia, Anesthesia Awareness, Nociceptive Pain, Pediatric ALL
- Trial name
- NCT04826146
- Testing
- Validation of qCON versus BIS
- Where
- 2 sites in Spain
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Patricio Gonzalez Pizarro
Strabismus, Anesthesia, General
The Effect of Anaesthesia Depth on Oculo-cardiac Reflex
This study was designed to determine the effect of the depth of anesthesia on the oculocardiac reflex (OCR) during pediatric strabismus surgery.
- Trial name
- NCT02379546
- Testing
- Desflurane, Bispectral index monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Tokat Gaziosmanpasa University
Tethered Spinal Cord, Brain Tumor
Dexmedetomidine on Intraoperative Somatosensory and Motor Evoked Potential Monitoring During Neurosurgery in Pediatric Patients
The investigators want to know if using the study drug dexmedetomidine will improve nerve wave readings during neurosurgery. These readings are done many times during surgery while the patient is asleep.
- Conditions
- Tethered Spinal Cord, Brain Tumor, Cranio Cervical Compression
- Trial name
- NCT01512147
- Testing
- Isoflurane, Propofol, Dexmedetomidine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Oregon Health and Science University