Clinical trials: Monitoring
COVID-19
Clinical Decision Support System Based on Non-invasive Tele-monitoring of COVID-19 Patients
The aim of the study is to provide clinical decision support to healthcare professionals using a wearable for non-invasive multimodal monitoring, allowing early detection of disease progression to severe forms, as well as the…
- Trial name
- SOY+ (NCT04802018)
- Testing
- Clinical decision support system based on non-invasive multimodal monitoring
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Increase-Tech
Diabetes Mellitus
Integration of Continuous Glucose Monitoring Into a BiHormonal Closed-Loop Artificial Pancreas
The investigators hypothesize that our closed-loop glucose-control system can provide BG control in subjects with type 1 diabetes using the estimated BG signal from a CGM as the input signal to the controller.
- Trial name
- CL2 (NCT01161862)
- Testing
- Bi-hormonal (insulin and glucagon) artificial pancreas
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Boston University Charles River Campus
Intracranial Aneurysm, Brain Edema
Goal-Directed Intraoperative Fluid Management Using FloTrac© Monitoring in High-Risk Neurosurgical Patients
This is a prospective, randomized controlled trial to determine if using FloTrac/EV1000 system in neurosurgical patients undergoing craniotomies for aneurysm repair or tumor resection complicated by cerebral edema, or complex…
- Conditions
- Intracranial Aneurysm, Brain Edema, Scoliosis, Surgery
- Trial name
- NCT02701582
- Testing
- Phenylephrine, Epinephrine, Albumin
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- NYU Langone Health
Cystic Fibrosis
Monitoring Response to Orkambi in Cystic Fibrosis Lung Disease by Inhaled Xenon MRI
This is an observational study for children with Cystic Fibrosis (CF) who are eligible based on their CF gene type. One group will be called the treatment group because they have the gene type (homozygous F508del) that makes them…
- Trial name
- NCT02848560
- Testing
- Hyperpolarized Xenon
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Chronic Disease, Child
Motivated to Move: A Study to Determine the Feasibility of Self-Monitoring Physical Activity in Youth
Children with a medical condition don't get enough exercise, which can lead to even more health problems in childhood and adulthood.
- Conditions
- Chronic Disease, Child, Adolescent
- Trial name
- NCT03970369
- Testing
- Usual care, Monitor
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- McMaster University
Diabetes Mellitus, Type 2
GLucose Monitoring Programme SingaporeE (GLiMPSE)
This phase 1 study is a non-randomized, single-arm, multi-center study that is designed to evaluate the feasibility and acceptability of the flash glucose monitoring system together with a structured education programme in…
- Trial name
- GLiMPSE (NCT03837262)
- Testing
- Flash Glucose Monitoring and structured education
- Where
- 3 sites in Singapore
- Volunteers
- 35 people
- Sponsor
- Singapore General Hospital
Prostatic Hyperplasia
Prescription Event Monitoring in Patients With Benign Prostatic Hyperplasia (BPH)
Study to evaluate the safety profile of Secotex® in the improvement of the symptoms of Benign Prostatic Hyperplasia in real clinical practice
- Trial name
- NCT02244346
- Testing
- Secotex®
- Volunteers
- 811 people
- Sponsor
- Boehringer Ingelheim
B-All, Acute Lymphoblastic Leukemia
A Multicenter Study to Evaluate Next-Generation Sequencing (NGS) Testing and Monitoring of B-Cell Recovery to Guide Management Following Chimeric Antigen Receptor T-cell (CART) Induced Remission in Children and Young Adults With B Lineage Acute Lymph...
Background: Chimeric antigen receptor T-cell (CART) therapy is a form of immunotherapy which can be used to treat people with relapsed B-ALL.
- Trial name
- NCT05621291
- Testing
- NGS testing
- Where
- 8 sites in United States
- Volunteers
- 60 people
- Sponsor
- National Cancer Institute (NCI)
Thyroid Cancer, Thyroid Cancer, Papillary
Intraoperative Neuromuscular Monitoring and Its Impact on Pre- and Postoperative Acoustic Outcomes in Thyroid Surgery
This study examines the impact of intraoperative recurrent laryngeal nerve monitoring signal changes on the postoperative voice quality of thyroid surgery patients.
- Trial name
- NCT06254859
- Testing
- Traditional thyroid surgery.
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Fujian Medical University
Sepsis, Infection
Improving Dosing of Vancomycin in Young Infants With Infections
Current dosing regimens for vancomycin result in many young infants not reaching the target level of vancomycin in the blood at steady state (when the blood is in equilibrium at 24-48 hours).The purpose of this study is to assess…
- Conditions
- Sepsis, Infection, Bacteremia
- Trial name
- VANCAPP (NCT04044703)
- Testing
- Vancomycin - model-based dosing regimen
- Where
- 4 sites in Australia
- Volunteers
- 44 people
- Sponsor
- Murdoch Childrens Research Institute
Amyotrophic Lateral Sclerosis
Validation of Czech Language Versions of Questionnaires for ALS Patients' Functional Status and Biomarker Long-term Follow-up
Questionnaires and scales used to assess the clinical status and quality of life of patients with amyotrophic lateral sclerosis (ALS) are an important tool to monitor the disease progression and current needs of patients.
- Trial name
- NCT06426030
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- Masaryk University
Medication Adherence, HIV Drug Resistance
Sustainable Adherence and Prevention of HIV Drug Resistance in Adolescents
The overall goal of this study is to determine if implementation of a package of interventions that includes DBS-based VL monitoring, coupled with an evidence-based intervention to improve ART adherence using cognitive-behavioral…
- Trial name
- SAPHRA (NCT03928834)
- Testing
- Adapted Nzira Itsva
- Where
- Zimbabwe
- Sponsor
- University of Zimbabwe
Heart Defects, Congenital, Pediatrics
CHAMP App Cardiac Study and Repository
This is a multi-site research study with an optional research repository that will consist of clinically derived data and photographic or video images of patients in the home setting with complex health conditions to evaluate the…
- Trial name
- CHAMP (NCT06034392)
- Testing
- CHAMP App
- Where
- 9 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Lori Erickson
Depression - Major Depressive Disorder, Anxiety
AcceXible Speech-Based Screening for Depression and Anxiety in University Students (BUAP, Mexico)
Major depressive disorder (MDD) and anxiety are increasingly prevalent among university student populations, yet early detection remains reliant on psychometric instruments tied to diagnostic criteria (e.g., PHQ-9, GAD).
- Trial name
- NCT07553130
- Testing
- AcceXible
- Where
- Mexico
- Volunteers
- 785 people, healthy volunteers welcome
- Sponsor
- Accexible
Sleep Apnea
Validation of Portable Monitoring Device for Diagnosing Sleep Apnea
portable monitoring device could diagnose sleep apnea in high risk patients.
- Trial name
- NCT00628511
- Testing
- ARES (Apnea Risk Evaluation System)
- Where
- China
- Volunteers
- 175 people
- Sponsor
- Chinese University of Hong Kong
Preterm Infants
Protocol-driven Nutrition in Preterm Infants
The project is a national, prospective, multicenter, interventional pilot project focused on protocol-driven nutrition in preterm infants in the Czech republic.
- Trial name
- NCT07364500
- Testing
- Nutrition plan supported by advanced clinical nutrition software
- Where
- 5 sites in Czechia
- Volunteers
- 400 people
- Sponsor
- Institute of Health Information and Statistics of the Czech Republic
Neurologic Disorders
Monitoring Everyday Life Motor Activity in Children
The overall aim of this project is to monitor everyday life activity of children with neurological disorders undergoing rehabilitation using wearable sensors capable of accurate and unobtrusive long-term measurement.
- Trial name
- MELMAC (NCT02236091)
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Rob Labruyere
Vital Signs Monitoring, Physiologic Monitoring
Validation of a Wireless Wearable Vital Signs Monitor in Pediatric Patient
This prospective observational study aims to evaluate the accuracy, safety, and feasibility of the ANNE® Chest wireless wearable sensor for continuous monitoring of heart rate, respiratory rate, oxygen saturation, and skin…
- Trial name
- NCT07739823
- Testing
- ANNE® Chest Sensor
- Volunteers
- 42 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Asthma, Cystic Fibrosis
FLAME: Airway Inflammation Monitoring in Asthma and Cystic Fibrosis
Background By means of measurements of series of non-invasive inflammatory markers in exhaled breath (condensate), a reflection of inflammatory processes and oxidative stress, can be obtained.
- Trial name
- NCT00404859
- Where
- 4 sites in Netherlands
- Volunteers
- 70 people
- Sponsor
- Maastricht University Medical Center
General Surgery, Anaesthesia
BIS Monitoring of the Depth of Anaesthesia in Children
General anaesthesia (GA) is, according to many definitions, the greatest gift presented to the medical art (S. B. Nuland). One of the aims of GA is to achieve the optimal depth of anaesthesia and rapid emergence from general…
- Trial name
- NCT02664142
- Testing
- BIS Group, Non-BIS Group, Anaesthetics
- Where
- Czechia
- Volunteers
- 220 people
- Sponsor
- University Hospital Ostrava
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