Clinical trials: Morbid Obesity
Morbid Obesity
Study on the Appropriateness of Bariatric Surgery in Adolescents
single-center study carried out in order to evaluate in prospective among patients seen or treated in the pediatric endocrinology unit and multidisciplinary management of obesity, the potential number of patients eligible for…
- Trial name
- NCT01249950
- Testing
- feasibility
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Toulouse
Obesity, Extreme Obesity
Low-level Intervention for Adolescents With Extreme Obesity
While adolescents with obesity and extreme obesity are at increased risk for health complications, especially adolescents with extreme obesity rarely seek medical care, and sustained weigh loss is hardly ever achieved.
- Trial name
- STEREO (NCT01703273)
- Testing
- manual based low key group intervention (innovation), standardized, manual based routine care
- Where
- 6 sites in Germany
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Martin Wabitsch
Severe Obesity
Enhancing Weight Loss Maintenance With GLP-1RA (BYDUREON™) in Adolescents With Severe Obesity
Long-term weight loss maintenance is seldom achieved by individuals with obesity owing to numerous biological adaptations involving appetite, satiety, and energy expenditure in the post- weight loss setting.
- Trial name
- NCT02496611
- Testing
- Weight loss with pharmacotherapy, Weight loss without pharmacotherapy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Atelectasis, Pulmonary Infection
Bi-PAP vs Sham Bi-PAP on Pulmonary Function in Morbidly Obese Patients After Bariatric Surgery
The effect of biphasic positive airway pressure (Bi-PAP) at individualized pressures on the postoperative pulmonary recovery of morbidly obese patients (MOP) undergoing open bariatric surgery (OBS) and possible placebo…
- Conditions
- Atelectasis, Pulmonary Infection, Chronic Obstructive Pulmonary Disease (COPD), Pulmonary Disease
- Trial name
- NCT03438383
- Testing
- Bi-PAP
- Volunteers
- 48 people
- Sponsor
- Evangelismos Hospital
Morbid Obesity Requiring Bariatric Surgery
Can Pre-operative Lean Mass Predict Weight Loss After Roux-en-Y Gastric Bypass?
The goal of this observational study is to evaluate whether preoperative fat-free mass predicts post-operative weight loss in patients undergoing Roux-En-Y gastric bypass.
- Trial name
- FLAG (NCT07565051)
- Where
- Switzerland
- Volunteers
- 91 people
- Sponsor
- University Hospital, Geneva
Morbid Obesity
Local GIT Hormones After Bariatric Maneuvers
Background: Many of the beneficial metabolic effects of bariatric surgery have been attributed to altered peptide hormone profiles, especially involving pancreatic and gut peptides.
- Trial name
- NCT04414072
- Testing
- sleeve gastrectomy with loop bipartition
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Minia University
Childhood Obesity
Magnetic Resonance Imaging Assessment of Multiorgan Health in Obesity
The goal of this study is to quantify the body composition and organ fat distribution changes with obesity interventions in adolescents with severe obesity.
- Trial name
- FIT-YOUNG (NCT07702825)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Alder Hey Children's NHS Foundation Trust
Morbid Obesity
"Hachi Barie" Project - A Multidisciplinary Program to Accompany Severely Obese Teenagers in the Weight Loss Process for the Benefit of Their Recruitment Into the Israel Defense Forces
Teenagers with body mass values (BMI) above 35 kg/m2 and co-morbidity are designated for medical disqualification from service in the IDF.
- Trial name
- NCT06102538
- Testing
- # The importance of service in the IDF # Physical activity # Healthy nutrition # Psychological support
- Where
- Israel
- Volunteers
- 25 people
- Sponsor
- Sheba Medical Center
Obesity, Extreme Obesity
Economic Aspects of Extreme Obesity in Adolescent
Obesity is one of the biggest public health challenges today and in the years to come, particularly due to its rising prevalence in children and adolescents.
- Trial name
- YES (NCT01632098)
- Where
- 5 sites in Germany
- Volunteers
- 429 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Obesity, Extreme Obesity
Weight Loss Surgery in Adolescents With Extreme Obesity
The use of bariatric surgery in adolescents is controversial. On one side, bariatric surgery is the only effective treatment to achieve sustained weight loss in adults with extreme obesity.
- Trial name
- YES (NCT02062164)
- Testing
- bariatric surgery, conservative care
- Where
- 5 sites in Germany
- Volunteers
- 66 people
- Sponsor
- Prof. Dr. Martin Wabitsch
Gestational Diabetes Mellitus in Pregnancy, Macrosomia, Fetal
Late Gestational Diabetes Mellitus Diagnosis in Obese Women
In the current work, we aim to perform a prospective study that will investigate the relationship between maternal obesity (BMI >30 kg/m2) and morbid obesity (BMI >35 kg/m2) with a late GDM diagnosis (>32 weeks), with an emphasis…
- Conditions
- Gestational Diabetes Mellitus in Pregnancy, Macrosomia, Fetal, Dystocia, Shoulder, Neonatal Jaundice
- Trial name
- NCT05510518
- Testing
- oral glucose tolerance test (OGTT)
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Western Galilee Hospital-Nahariya
Obesity, Morbid, Metabolic Syndrome
The UFO (Ultra Processed Foods in Obesity) Project
The childhood obesity prevalence has increased dramatically in the last decades, affecting more than 340 million children worldwide.
- Trial name
- UFO Project (NCT05554016)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Federico II University
Obese Adolescents, Obesity, Morbid
ESG in Obese Adolescents
The primary goal of this pilot study is to learn if the use of the Apollo Endosurgery ESG System is a safe, well tolerated intervention for weight loss in adolescents with obesity.
- Conditions
- Obese Adolescents, Obesity, Morbid, Obesity/Therapy
- Trial name
- NCT06914765
- Testing
- Endoscopic Sleeve Gastroplasty (ESG) Procedure
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital of Philadelphia
Morbid Obesity
Probiotics Improve Gastrointestinal Symptoms After Roux-en-Y Gastric Bypass: A Prospective Randomized Trial
Obesity has been a global epidemic. Currently, bariatric surgery has been recognized as the only successful treatment for morbid obesity.
- Trial name
- NCT01431651
- Testing
- probiotics,digestive enzyme
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Min-Sheng General Hospital
Gastroesophageal Reflux
Prevalence, Predictors and Management of Gastroesophageal Reflux After Laparoscopic Sleeve Gastrectomy
From January 2017 to January 2022, we looked at patients who had primary LSG and developed GERD. Before and after surgery, patients for LSG performed barium meal in Trendelenburg position and upper GIT endoscopy.
- Trial name
- LSG-GERD (NCT05416645)
- Testing
- patients with GERD after LSG
- Where
- Egypt
- Volunteers
- 1,537 people
- Sponsor
- Mansoura University
Morbid Obesity
Fentanyl Metabolism in Obese Adolescents
Fentanyl is a frequently used pain medication in pediatric and adult anesthesia. Although there are some studies considering the breakdown of oral, transmucosal and intravenous fentanyl preparations in children, the disposition…
- Trial name
- NCT01955993
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute
Overweight and Obesity, Severe Obesity
Connect for Health Pediatric Weight Management Program
The overall aim of this study is to disseminate the evidence-based Connect for Health program, specifically targeting pediatric primary care practices that deliver care to low-income children in the US who have a…
- Trial name
- NCT04042493
- Testing
- Connect for Health
- Where
- 3 sites in United States
- Volunteers
- 19,304 people
- Sponsor
- Massachusetts General Hospital
Morbid Obesity, Pulmonary Embolism
Laparoscopic Bariatric Surgery: Two Regimens of Venous Thromboprophylaxis: Prospective Randomized Study
Obese patients undergoing bariatric surgery warrant VTE prophylaxis because they are at high risk for developing a fatal pulmonary embolism or postthrombotic syndrome.
- Trial name
- NCT02128178
- Testing
- Enoxaparin 40 mg 2 hours before arm, Enoxaparin 40 mg 12 hours before arm
- Where
- Egypt
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Intubation;Difficult, Obesity, Morbid
Pre-Operative Airway Assessment of Patients With Morbid Obesity
Backround:The incidence of difficulty in laryngoscopy and endotracheal intubation is more common in obese patients. There are conflicting data on factors predicting difficult intubation.
- Trial name
- NCT04542187
- Where
- Turkey (Türkiye)
- Volunteers
- 121 people
- Sponsor
- Bagcilar Training and Research Hospital
Sleep Disturbance, Obesity, Severe
6th Month EWL% After Sleeve Gastrectomy to Get a Better Sleep Quality
Obesity, caused by caloric intake over output, has become a global health problem. The relationship between sleep and obesity is widely discussed in the literature.
- Conditions
- Sleep Disturbance, Obesity, Severe, Surgery
- Trial name
- NCT05608031
- Testing
- Pittsburgh sleep quality index (PSQI) scale
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Umraniye Education and Research Hospital