Clinical trials: Morbidity
Newborn Morbidity, Newborn Complication
Feasibility Study Evaluating the Efficacy of a Wireless Vital Signs Monitor for Critically Ill Newborns in Kenya
The neoGuard device is a 4-in-1 wearable vital signs monitor designed to continuously measure temperature, pulse rate (PR), respiratory rate (RR) and blood oxygen saturation (SpO2) in newborns.
- Trial name
- NCT04606589
- Testing
- neoGuard vital signs monitor
- Where
- Kenya
- Volunteers
- 167 people
- Sponsor
- Neopenda, PBC
Prematurity
Preterm Donor Human Milk Supplementation of Mother's Own Milk in VLBW Infants
This prospective randomized controlled trial aims to investigate whether feeding very low birth weight (VLBW) infants with Mother's own milk (MOM) supplemented with either preterm (PDM) or term donor milk (TDM), when MOM is…
- Trial name
- NCT05675397
- Testing
- donor human milk
- Where
- 2 sites in Greece
- Volunteers
- 200 people
- Sponsor
- National and Kapodistrian University of Athens
Morbidity;Perinatal, Pregnancy Complications
Postpartum Outcomes in BC
For every case of maternal death, many more women experience life-threatening complications during pregnancy and childbirth. Yet, severe maternal morbidity (SMM) cases are often overlooked post-delivery.
- Conditions
- Morbidity;Perinatal, Pregnancy Complications, Pregnancy Related
- Trial name
- NCT05461183
- Testing
- Retrospective database analysis
- Volunteers
- 15,000 people
- Sponsor
- University of British Columbia
Tracheal Intubation Morbidity, Emergency Medicine
Tracheal Intubation and Prehospital Emergency Setting
In prehospital emergency setting, tracheal intubation is a frequent procedure (8% of interventions). Its objective is to control and protect upper airways and to optimize ventilation and oxygenation in patients with…
- Trial name
- SMURIDS (NCT03486171)
- Where
- 5 sites in France
- Volunteers
- 1,200 people
- Sponsor
- University Hospital, Bordeaux
Twin Pregnancy
Planned Vaginal Delivery vs Planned Cesarean Delivery in Preterm Twins
The incidence of twin pregnancies has increased and currently accounts for 1.8% of all deliveries. 47.5% of twins are born prematurely (vs. 6% for singletons) of which 9.9% before 32SA.
- Trial name
- NCT04232436
- Testing
- Survival at discharge, Survival without severe morbidity
- Where
- France
- Volunteers
- 204 people
- Sponsor
- University Hospital, Montpellier
Fetal Malnutrition
Assessment by the CANS Score Versus Anthropometry and Impact on Early Neonatal Morbidities
Assessment of malnutrition within 48 hours of birth through anthropometric indices as Weight, Length and Head circumference, Proportionality indices as MAC/HC ratio, Ponderal index and Body mass index, Clinical assessment of…
- Trial name
- NCT03466853
- Testing
- Clinical assessment of nutritional status (CANS) score, Anthropometric indices, Proportionality indices
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Cairo University
Wound Sepsis
Efficacy of Adding Azithromycin to Cephalosporin Before Cesarean Delivery
efficacy of adding azithromycin to cephalosporin before cesarean delivery
- Trial name
- NCT04062175
- Testing
- cephalosporin, Azithromycin Tablets
- Where
- Egypt
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Adrenal Cortex Diseases, Infant Morbidity
Adrenal Responsiveness During the Perioperative Period in Children Undergoing Congenital Cardiac Surgery
Our objective was to determine whether a standard 1mg/kg intraoperative dose of dexamethasone results in similar drug levels for all patients and to characterize the relationship between these drug levels and the innate stress…
- Trial name
- NCT01839812
- Testing
- Cosyntropin
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Mayo Clinic
Malnutrition; Degree, Moderate, Diet Habit
The Effect of Double Duty Interventions on Double Burden of Malnutrition Among School Adolescents in Ethiopia
The goal of this cluster randomized controlled trial is to determine the effect of double duty interventions on double burden of malnutrition, dietary diversity score, and frequency of morbidity among secondary school adolescents…
- Conditions
- Malnutrition; Degree, Moderate, Diet Habit, Undernutrition, Overnutrition
- Trial name
- DBM (NCT05574842)
- Testing
- Double duty interventions using nutrition behavior change communication approach
- Where
- Ethiopia
- Volunteers
- 742 people
- Sponsor
- Debre Berhan University
Anemia, Inflammation
Acute vs. Delayed Iron Therapy: Effect on Iron Status, Anemia and Cognition
The research questions to be answered by this study are: 1. Is treatment with iron more effective at improving anemia if given at the time of a malaria episode or 1 month after the episode? 2.
- Conditions
- Anemia, Inflammation, Malaria Morbidity, Cognitive Development
- Trial name
- NCT01093989
- Testing
- Ferrous Sulphate Syrup
- Where
- Uganda
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Cleft Lip and Palate, Maxillary Hypoplasia
Cleft Orthognathic Surgery Versus Distraction Osteogenesis - Which is Better?
Cleft lip and palate patients normally present with a sunken face due to collapse in the middle part of the face and inability of the upper and lower teeth to meet during chewing.
- Trial name
- NCT00930124
- Testing
- Orthognathic surgery, Distraction osteogenesis
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Pediatric Cardiac Surgery, Gender
Gender Influence on Morbi-mortality in Pediatric Cardiac Surgery.
Recent studies show an important influence of gender on inflammatory reactions. Cardiac surgery is associated with a major systemic inflammatory response.
- Trial name
- NCT04452539
- Testing
- Paediatric cardiac surgery
- Where
- Belgium
- Volunteers
- 1,500 people
- Sponsor
- Brugmann University Hospital
Genetic Disease, Newborn Morbidity
Newborn Genomics Programme
Genomic methods can significantly contribute to all facets of precision medicine, from diagnosis to prevention, therapeutic intervention, and management of acute and chronic illnesses.
- Trial name
- NCT06081075
- Testing
- Genetic testing
- Where
- New Zealand
- Volunteers
- 500 people
- Sponsor
- Liggins Institute
Pain
Reducing Operative and Post-operative Morbidity in Living Kidney Donors With the Airseal System
The purpose of this study is to determine if the Airseal System will reduce post-operative pain and reduce the need for narcotics in laparoscopic living kidney donor surgeries.
- Trial name
- NCT02262039
- Testing
- Valveless recirculating insufflation (VTI), Conventional pressure
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Yale University
Mortality
WittyFit - Live Your Work Differently
Individuals spend one third of their life working. Age of retirement is regularly pushed back. The main challenge in the nearest future will be to maintain workers health to deal with their work till retirement.
- Trial name
- WittyFit (NCT02596737)
- Testing
- wittyFit concept
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Congenital Heart Defect
The Effects of Inhaled Nitric Oxide After Fontan Operation
Pleural effusions continue to be a post-operative complication seen after Fontan operation. This study will examine the use inhaled nitric oxide (iNO) given for 54 hours after Fontan operation to improve fluid balance.
- Trial name
- NCT00945529
- Testing
- inhaled nitric oxide (iNO)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Ellen Spurrier
Perinatal Morbidity
Post Term Pregnancy - Induction of Labor or Monitoring of Pregnancy
Post term pregnancy is a risk pregnancy. Aim of the study was to investigate whether induction of labor at gestational age 289(41 weeks+2 days) reduces neonatal morbidity compared to expectant management.
- Trial name
- NCT00385229
- Testing
- induction of labor
- Where
- Norway
- Volunteers
- 508 people
- Sponsor
- St. Olavs Hospital
Malaria
Baseline Cohort Malaria Morbidity Study
The BLOOMy study is a longitudinal prospective cohort study of healthy children to assess the incidence of clinical malaria over the main transmission season.
- Trial name
- BLOOMy (NCT04601714)
- Where
- Burkina Faso
- Volunteers
- 459 people
- Sponsor
- Groupe de Recherche Action en Sante
Postoperative Morbidity
Investigating Trends in Compliance With Quality Assurance Metrics
Over 40 million major operative procedures are performed in the US annually and comprise about 40% of healthcare expenditures. Despite decades of research, perioperative mortality and morbidity remain a major healthcare system…
- Trial name
- NCT03119532
- Testing
- Receive metric feedback email
- Volunteers
- 672 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Postoperative Mortality
Evaluation of Co-morbidity Scales
Peri-operative mortality depends on the patient's co-morbidities. ASA Physical Status (American Society of Anesthesiology) is the most commonly scale to assess this parameter and has yet been repeatedly criticized in the past for…
- Trial name
- Ko-MoSkau (NCT01810133)
- Where
- Germany
- Volunteers
- 230,034 people
- Sponsor
- Charite University, Berlin, Germany