Clinical trials: Morphine
Child Behavior Disorders
Using Mobile Technology to Enhance Multisystemic Therapy (MST) Outcomes
The goal of the current trial is to assess the feasibility of a newly developed prototype of a cell phone app called VillageWhere.
- Trial name
- VillageWhere (NCT02320903)
- Testing
- VillageWhere App
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Evidence-Based Practice Institute, Seattle, WA
a Single-Dose of Etoricoxib, Post-Operative Morphine Consumption
Pre-Emptive Analgesia Efficacy of Etoricoxib for Postoperative Pain
Taken together, studies of the value of pre-emptive analgesia are inconclusive. This randomized, double-blind, dose-ranging, placebo-controlled study was therefore designed to test that a reduction in post-operative morphine…
- Conditions
- a Single-Dose of Etoricoxib, Post-Operative Morphine Consumption, Total Pain Relief Over 8 Hr(TOPAR8), Post Transabdominal Hysterectomy
- Trial name
- NCT00149253
- Testing
- a single-dose of Etoricoxib before induction of anesthesia
- Where
- Thailand
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Brachial Plexus Injury
Incidence of Brachial Plexus Injury After Rotator Cuff Repair With Continuous Interscalene Block
Brachial plexus injury after shoulder surgery with continuous interscalene block is 2.4% at 1 month and 0% at 6 months, but may be higher with a systematic postoperative neurological examination.
- Trial name
- NCT01334632
- Testing
- Continuous interscalene block, PCA morphine
- Where
- Switzerland
- Volunteers
- healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Pediatric Obstructive Sleep Apnea Syndrome
Investigating the Safety of Post-surgical Analgesics in Children With Obstructive Sleep Apnea
Every year thousands of young children with obstructive sleep apnea undergo surgery which requires them to be prescribed pain medication.
- Trial name
- NCT01680939
- Testing
- Morphine, Ibuprofen
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Inguinal Hernia
Effect of IV Nalbuphine on Nausea and Vomiting Following Intrathecal Morphine
the study aimed to investigate the effect of Iv nalbuphine on postoperative nausea and vomiting and pain with intrathecal morphine on inguinal hernia repair surgery.
- Trial name
- NCT05704673
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Post-operative Pain
How Does Gabapentin Affects Post-operative Tonsillectomy Pain?
Gabapentin is a medicine that has been used in adults (but not yet in children) to treat pain after surgery. In children it has been used for many years to treat other conditions and has been shown to be very safe.
- Trial name
- NCT00624455
- Testing
- Gabapentin
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Obstructive Sleep Apnea
Fentanyl Test in Children's Adenotonsillectomy
The purpose of this study is to discuss the relationship between the result of fentanyl test and required dosage of morphine for children with OSAS after adenotonsillectomy；and to evaluate the ability of predicting requested…
- Trial name
- NCT02484222
- Testing
- Fentanyl
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Anesthesia, Opioid Use
Opioid-Free Anesthetic for Tonsillectomy
Prospective randomized controlled trial to determine if opioid-free anesthetic for tonsillectomy is non-inferior to standard opioid-containing anesthetic
- Conditions
- Anesthesia, Opioid Use, Tonsillitis, Sleep Disorder
- Trial name
- NCT04528173
- Testing
- Ketorolac, Dexmedetomidine, Morphine
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Brain Tumors
Integrated Pulmonary Index and Opioid Based Patient Controlled Analgesia
An optimal analgesic therapy is very important for postoperative recovery. In recent years, several studies showed that the prevalence of the moderate to severe pain after craniotomy ranged from 69 to 87% of patients.
- Trial name
- NCT04313374
- Testing
- Morphine PCA 1 mg, Morphine PCA 0,5 mg
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Caesarean Section; Pain
Parecoxib vs. Dexketoprofen for the Management of Pain After Cesarean Section.
Although it is known that parecoxib and dexketoprofen are commonly used in successful post-operative pain relief, there are very few studies that compare these two agents in their individual applications and/or combined with…
- Trial name
- NCT04847024
- Testing
- Parecoxib, Dexketoprofen
- Where
- Panama
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Saint Thomas Hospital, Panama
Malaria
Impact of Dihydroartemisinin-piperaquine Plus Primaquine on Malaria Transmission in Lampung Province, Sumatra
Artemisinin-based combination therapy (ACT) has been known to be controversial for stopping malaria transmission. The addition of primaquine (PQ) - the only drug commercially available that kills mature transmission stage - to…
- Trial name
- NCT01389557
- Testing
- Dihydroartemisinin-piperaquine with primaquine
- Where
- Indonesia
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Pain
Pharmacokinetics of Oral Morphine and Pharmacogenomics of CYP2D6 and UGT2B7, in an Urban Pediatric Population Presenting for Elective Surgery
The purpose of this study is to identify and collect samples from children who have taken a single oral dose of the pain medication morphine, and to determine the genetic differences in the way children metabolize (break down in…
- Trial name
- NCT01071499
- Testing
- Morphine
- Where
- Canada
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Upper Extremity Fractures, Analgesia Post Fracture
Oral Morphine Versus Ibuprofen
Children 5-17 years of age who have sustained a non-operative distal forearm (radius and/or ulna) or clavicular fracture will be randomized to receive either ibuprofen or oral morphine as needed for pain relief for the first 24…
- Trial name
- NCT01690780
- Testing
- Oral morphine, Ibuprofen
- Where
- Canada
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Naveen Poonai
Pain, Drug Effect
Development of a Morphine Pharmacokinetic and Pharmacodynamic Model for the Neonatal Population
This research aims to study what the baby's body does with morphine and how morphine works in the baby's body. One hundred newborn babies will be enrolled in this study.
- Trial name
- NCT03035578
- Testing
- Morphine
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Post-Traumatic Headache, Acute Pain
Titrated Versus High and Low Dose Nebulized Morphine to Reduce Pain in Emergency Settings
The investigators test a different technique using morphine to improve pain relief in patient visiting the emergency department with acute trauma pain, for this we are comparing three different methods of morphine administration…
- Trial name
- TIMORNEB (NCT02200185)
- Testing
- IV titrated morphine, Low dose nebulised morphine, High dose nebulised morphine
- Where
- Tunisia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Monastir
Opioid Use, Unspecified
Methadone vs. Fentanyl Administration on Postoperative Pain Control in Pediatric Patients Undergoing Cardiac Surgery
The purpose of this study is to determine if methadone improves postoperative pain control in pediatric patient's undergoing cardiac surgery.
- Trial name
- CV_RCT_M_F (NCT02747875)
- Testing
- Methadone, Fentanyl
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Andrew Waberski
Malaria
Surveillance and Treatment With Dihydroartemisinin-piperaquine Plus Primaquine
Mass Drug Administration (MDA) and Mass Screening and Selective Treatment (MST) might be applied as strategies for eliminating malaria when focusing on transmission stages.
- Trial name
- NCT01878357
- Testing
- dihydroartemisinin-piperaquine, primaquine
- Where
- Indonesia
- Volunteers
- 1,488 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Electroconvulsive Therapy, Major Depressive Disorder
Multimodal Clinical Study of Electroconvulsive Therapy and Magnetic Seizure Therapy
To compare the efficacy and tolerability of Electroconvulsive Therapy (ECT) and Magnetic Seizure Therapy (MST) in patients with major depressive disorder (MDD).
- Conditions
- Electroconvulsive Therapy, Major Depressive Disorder, Magnetic Seizure Therapy
- Trial name
- NCT07473648
- Testing
- Electroconvulsive Therapy, Magnetic Seizure Therapy
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Anhui Medical University
Post-operative Pain
Post-operative Oral Morphine Versus Ibuprofen
Children 5-17 years of age who have undergo orthopedic day surgical procedures for definitive management of fractures, tendon release, etc.
- Trial name
- NCT01686802
- Testing
- oral morphine, Ibuprofen
- Where
- Canada
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Pediatric Sleep Apnea, Obesity
Sleep Apnea and Obesity Affects on Morphine Pharmacokinetics
Adenotonsillectomy (AT) is one of the most common pediatric surgeries performed, and is estimated to comprise 530,000 procedures in children under 15 years of age.
- Conditions
- Pediatric Sleep Apnea, Obesity, Morphine Metabolism
- Trial name
- NCT02732795
- Testing
- Morphine pharmacokinetic evaluation
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University