Clinical trials: Motility Function
Functional and Motility Related Gastrointestinal Disorders Such as Irritable Bowel Syndrome and Functional Dyspepsia
A Pharmacy-based Study to Learn More About How Well Iberogast Works, How it Affects the Body, How it is Used, and User Satisfaction in Patients With Functional and Motility-related (Stomach and Bowel Movement-related) Gastrointestinal Diseases, Including Irritable Bowel Syndrome
Researchers want to learn more about the day-to-day use of Iberogast in people who have functional and motility-related gastrointestinal (stomach and bowel) diseases.
- Trial name
- NCT04993989
- Testing
- Iberogast (STW5, BAY98-7411)
- Where
- Germany
- Volunteers
- 843 people
- Sponsor
- Bayer
Primary Ciliary Dyskinesia
Respiratory Physiotherapy Performed by Simeox In Patients With Primary Ciliary Dyskinesia
Primary ciliary dyskinesia (PCD) is characterized by impaired airway clearance and mucus stagnation. This results in recurrent upper and lower respiratory tract infections often leading to chronic inflammation and, if not treated…
- Trial name
- NCT04793724
- Testing
- Simeox, PARI O PEP
- Where
- Czechia
- Volunteers
- 30 people
- Sponsor
- University Hospital, Motol
Amblyopia, Strabismus
VISION-3D: Visual Skills Improvement With On-screen 3D Movies.
This clinical study investigates whether watching 3D films can help improve the vision of children with residual amblyopia (lazy eye), that is, those children who, despite having undergone usual treatments such as glasses or…
- Trial name
- VISION3D (NCT07301645)
- Testing
- Stereoscopic (3D) Movie Viewing, 2D Movie Viewing
- Volunteers
- 40 people
- Sponsor
- Universitat Politècnica de Catalunya
HIPEC, Gastro Intestinal Cancer
Effects of HIPEC on Postoperative Bowel Motility and Complications
This retrospective cohort study was conducted at our institution, involving patients with gastric cancer, appendiceal mucinous neoplasm, or colon cancer who underwent CRS with or without HIPEC between January 2017 and December…
- Conditions
- HIPEC, Gastro Intestinal Cancer, Adhesion Prevention, Bowel Functions
- Trial name
- NCT07353177
- Testing
- Hyperthermic Intraperitoneal Chemotherapy (HIPEC)
- Where
- China
- Volunteers
- 193 people
- Sponsor
- Peking University People's Hospital
Primary Ciliary Dyskinesia
Muscle Function, Exercise Capacity and Physical Activity Level in Primary Ciliary Dyskinesia and Kartagener Syndrome
Studies evaluating respiratory and peripheral muscle functions in PCD patients and comparing them with healthy children are limited in the literature.
- Trial name
- NCT05816876
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Gazi University
Primary Ciliary Dyskinesia
Otolith Function in Patients With Primary Ciliary Dyskinesia
The purpose of this study is to determine whether patients with primary ciliary dyskinesia (PCD) have reduced or absent otolith function.The otolith system is a specific part of the inner ear vestibular (balance) system that…
- Trial name
- NCT01246258
- Testing
- Vestibular evoked myogenic potentials (VEMPs), Utricular centrifugation test
- Where
- United Kingdom
- Volunteers
- 5 people
- Sponsor
- Imperial College Healthcare NHS Trust
Primary Ciliary Dyskinesia
PRospective Observational Multicentre Study on VAriability of Lung Function in Stable PCD Patients
Using routinely collected clinical data, this study aims to quantify intra-individual (i.e. in the same individual) variations between measurements of lung function in stable patients with primary ciliary dyskinesia (PCD), a rare…
- Trial name
- PROVALF-PCD (NCT03704896)
- Testing
- Lung function measurement
- Where
- United Kingdom
- Volunteers
- 451 people
- Sponsor
- University of Southampton
Primary Ciliary Dyskinesia
Glycine and Magnesium+Thiamine for the Treatment of Primary Ciliary Dyskinesia
Patients with primary ciliary dyskinesia (PCD) have trouble with clearing their bronchi from mucus, which in the long-term may produce severe damage to the lungs.
- Trial name
- NCT06959251
- Testing
- Glycine, Magnesium+thiamine
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Instituto Nacional de Enfermedades Respiratorias
Primary Ciliary Dyskinesia
Chest Physiotherapy and Lung Function in Primary Ciliary Dyskinesia
Primary ciliary dyskinesia (PCD) is a rare disease, caused by impairment of the motile cilia. Patients present with chronic upper and lower respiratory tract infections.
- Trial name
- NCT01929356
- Testing
- Chest physiotherapy
- Where
- Belgium
- Volunteers
- 29 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Bowel Dysfunction, Dysmotility
Comparison of a New Non-invasive Device With the Invasive Gold-standard Investigation to Assess Function of the Large Bowel in Children
The goal of this clinical trial is to learn if the new non-invasive device (Body Surface Colonic Mapping) works to accurately assess colonic movement and function in children.The main questions it aims to answer are: Are Body…
- Conditions
- Bowel Dysfunction, Dysmotility, Hirschsprung Disease, Anorectal Malformations
- Trial name
- NCT07789782
- Testing
- Body Surface Colonic Mapping
- Where
- Australia
- Volunteers
- 50 people
- Sponsor
- Murdoch Childrens Research Institute
Vestibular Function Tests, Nystagmus Vestibular
Post- Rotatory Nystagmus Test: Normative Data for Spanish Adolescents and Adults
The vestibulo-ocular reflex is the motor response of our eyes in the opposite direction to a translational or rotational movement of our head.
- Trial name
- NCT04788134
- Testing
- Post-rotatory nystagmus test
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Quesada, Rocío Vico
Progressive Supranuclear Palsy, Cortical Basal Ganglionic Degeneration
tDCS as Treatment for Motor Function
Previous preliminary results are sufficiently impressive to suggest that tDCS stimulation does have the potential to improve motor function when that ability is trained during stimulation.
- Conditions
- Progressive Supranuclear Palsy, Cortical Basal Ganglionic Degeneration, Parkinson Disease
- Trial name
- PSP (NCT07291687)
- Testing
- Transcranial direct current stimulation (TDCS), Stimulation Arm
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Baycrest
Cystic Fibrosis (CF), Primary Ciliary Dyskinesia (PCD)
Exercise Capacity, Muscle Oxygenation, Respiratory Muscle Strength, and Physical Activity Level in Pediatric CF and PCD
Cystic fibrosis (CF) and primary ciliary dyskinesia (PCD) are genetic diseases characterized by chronic respiratory tract infections.
- Trial name
- NCT07157644
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Gazi University
Anisometropic Amblyopia, Strabismic Amblyopia
3D Movie Viewing vs Occlusion for Treating Amblyopia in Children
Amblyopia is a common childhood visual disorder that affects vision in one eye and can also impair depth perception (stereopsis).
- Trial name
- VISTA3D (NCT07563946)
- Testing
- 3D Movie Viewing, Occlusion Therapy
- Volunteers
- 56 people
- Sponsor
- Universitat Politècnica de Catalunya
Gastrointestinal Motility Disorders in Children, Hirschsprung Disease
Improvement of Understanding of Pediatric Sacral Neuromodulation: Therapeutic Strategies and Outcome Variables
The goal of this study is to learn about the effects of sacral neuromodulation in pediatric patients with gastrointestinal motility disorders.
- Conditions
- Gastrointestinal Motility Disorders in Children, Hirschsprung Disease, Constipation - Functional
- Trial name
- SMART-GUT (NCT07519915)
- Testing
- SNM/MRI/EMG
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Friedrich-Alexander-Universität Erlangen-Nürnberg
Reflux Esophagitis (RE), Non-erosive Reflux Disease (NERD)
Analysis of GERD Symptoms Using Gastroesophageal Reflux Impact Score Questionnaire for Quality of Life
Even the patients complain GERD symptoms such as heartburn and acid regurgitation the final diagnosis could be reflux esophagitis (RE), non-erosive reflux disease (NERD) and even functional heartburn (FH).
- Conditions
- Reflux Esophagitis (RE), Non-erosive Reflux Disease (NERD), Functional Heartburn (FH)
- Trial name
- NCT01536080
- Where
- South Korea
- Volunteers
- 207 people
- Sponsor
- Seoul National University Bundang Hospital
Erosive Reflux Disease, Non-erosive Reflux Disease
Predictors of Proton Pump Inhibitor Response in Gastroesophageal Reflux Disease Patients
Proton pump inhibitor (PPI) is widely used in patients with gastroesophageal reflux disease (GERD), however, some patients fail to respond to PPI therapy.
- Conditions
- Erosive Reflux Disease, Non-erosive Reflux Disease, Functional Heartburn
- Trial name
- NCT01797939
- Where
- South Korea
- Volunteers
- 197 people
- Sponsor
- Seoul National University Bundang Hospital
Irritable Bowel Syndrome (IBS)
Diet and Motility in IBS
The goal of this observational study is to identify factors that influence symptoms in children with irritable bowel syndrome (IBS), to find ways to make diet treatments work better and possibly create personalized plans to help…
- Trial name
- IBS (NCT07283341)
- Testing
- Wireless Patch System
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Cystic Fibrosis
The Prevalence and Significance of Gastro-oesophageal Reflux in Cystic Fibrosis Before and After Lung Transplantation
Gastro-oesophageal reflux (GOR) has been found to be prevalent in children with cystic fibrosis (CF)and may further worsen lung damage via reflex bronchospasm or pulmonary aspiration.
- Trial name
- NCT00164021
- Testing
- Physiotherapy, exercise, percutaneous gastrostomy feeds, Anti-reflux pharmacotherapy
- Where
- Australia
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Bayside Health
Gastroesophageal Reflux Disease (GERD), Eosinophilic Esophagitis (EoE)
Mucosal Impedance in Pediatric Population
Our hypothesis is that patients with GERD and/or Eosinophilic Esophagitis (EE) have lower esophageal impedance measurements when compared to patients who do not have GERD or EE.
- Conditions
- Gastroesophageal Reflux Disease (GERD), Eosinophilic Esophagitis (EoE), Functional Dyspepsia
- Trial name
- NCT02320981
- Testing
- Standard of Care esophagogastroduodenoscopy (EGD) with measurement of mucosal impedance
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center