Clinical trials: Motor Deficits
Cerebral Palsy, Neurological Conditions
Safety and Efficacy Study of Oral Glycopyrrolate Liquid for the Treatment of Pathologic (Chronic Moderate to Severe) Drooling in Pediatric Patients 3 to 18 Years of Age With Cerebral Palsy or Other Neurologic Conditions
This is an open-label clinical research study of an oral glycopyrrolate liquid for the treatment of chronic moderate to severe drooling in patients with cerebral palsy or other neurological conditions.
- Conditions
- Cerebral Palsy, Neurological Conditions, Mental Retardation, Sialorrhea
- Trial name
- NCT00491894
- Testing
- Oral Glycopyrrolate Liquid
- Where
- 7 sites in United States
- Volunteers
- 137 people
- Sponsor
- Shionogi
Neurofibromatosis 1
Antioxidant Therapy With N-acetylcysteine for Children With Neurofibromatosis Type 1
Children with neurofibromatosis type 1 (NF1) commonly suffer from the effects of cognitive, behavioral, and motor impairments. At present, there is no specific treatment for this NF1 complication.
- Trial name
- DoDNAC (NCT04481048)
- Testing
- N-Acetyl cysteine
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Attention-Deficit/Hyperactivity Disorder (ADHD), Physiotherapy
Effects of HIIT and Dual-Task Training in Children With ADHD
This randomized controlled study evaluated the effects of an 8-week high-intensity interval training (HIIT)-based dual-task exercise program on attention, cognitive-motor performance, social adjustment, and quality of life in…
- Trial name
- ADHD-HIIT-DT (NCT07863362)
- Testing
- High-Intensity Interval Training With Dual-Task Training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hasan Kalyoncu University
Conduct Disorder
Lisdexamfetamine For the Treatment of Conduct Disorder in Children
About 2 in every 100 Australian children have conduct disorder, a serious mental health condition characterised by antisocial behaviours like aggression and rule breaking.
- Trial name
- LiFT-CD (NCT07923617)
- Testing
- Lidexamfetamine
- Volunteers
- 30 people
- Sponsor
- Orygen
ADHD - Attention Deficit Disorder With Hyperactivity, Irritability
Predictors of Improvements in Irritability and Aggression in Children With ADHD Treated With CNS Stimulants
Impulsive Aggression and chronic irritability (IACI) often occur together and are one of the most common reasons children present for behavioral health (BH) care.
- Conditions
- ADHD - Attention Deficit Disorder With Hyperactivity, Irritability, Aggression Childhood
- Trial name
- NCT06871488
- Testing
- CNS Stimulant, CNS Stimulant open label first phase
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Milton S. Hershey Medical Center
Asperger's Syndrome, Dyslexia
My Scrivener® - Measuring Effectiveness and Dose Response in Children
This study will assess whether a computer haptic peripheral device programmed to provide repetitive motion training is as effective as the same repetitive motion training provided by a human being.
- Conditions
- Asperger's Syndrome, Dyslexia, Cerebral Palsy, Attention Deficit Disorder
- Trial name
- NCT00919906
- Testing
- My Scrivener(R)
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- Obslap Research LLC
Amyotrophic Lateral Sclerosis
A Physiotherapy Intervention Study in Patients With Amyotrophic Lateral Sclerosis (ALS)
This study investigates whether an individualized physiotherapy program, tailored to each patient's specific motor deficits, can better support physical function compared with usual care physiotherapy in people with ALS.
- Trial name
- Train ALS (NCT07341984)
- Testing
- Individualized Physiotherapy
- Where
- Switzerland
- Volunteers
- 38 people
- Sponsor
- Charlotte Vogt
Postural Balance
Effects of Transcranial Direct Current Stimulation on Balance of Children With Balance Deficit
Neural control of posture depends on interaction of sensory and motor information from multiple structures, including the primary motor cortex (M1).
- Trial name
- NCT04341220
- Testing
- Transcranial direct current stimulation (tDCS), Balance exercises
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Cardiac Surgery Requiring Cardiopulmonary Bypass, Brain Injury
The Association Between Tau & GFAP and Postoperative Neurological Impairment in Patients Undergoing Cardiac Surgery
Patients born with heart defects often undergo surgical procedures on a heart lung machine. With improvements in medical and surgical management, their survival has significantly improved, but their brain insult has not been paid…
- Conditions
- Cardiac Surgery Requiring Cardiopulmonary Bypass, Brain Injury, Congenital Heart Defect
- Trial name
- NCT06899971
- Testing
- Collecting discarded blood samples
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Boston Children's Hospital
Spinal Trauma With Neurological Deficit
TETRAM 2. Treatment With Erythropoetin in Patients With Spinal Trauma With Neurological Deficit, Maximum Tolerated Dose Study
The social, psychological, economic burden of Spinal trauma with deficit is great, and there is no curative treatment. Erythropoetin (EPO) is promising, due to its neuroprotective effects demonstrated in vitro, in vivo in animal…
- Trial name
- TETRAM2 (NCT00478517)
- Testing
- Erythropoetin (rHuEPO, EPREX®)
- Volunteers
- 20 people
- Sponsor
- Hospices Civils de Lyon
Pediatric Obesity
Energy Intake and Energy Deficit in Obese Adolescents
The aim of the present study is to compare the effect of two weight loss interventions inducing the same energy deficit but one based on exercise and one using dietary restriction, on appetite control in obese adolescents.
- Trial name
- IDEFIX (NCT03466359)
- Testing
- DEF-EI : Energy restriction induced energy deficit, DEF-EX : Exercise induced energy deficit
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Clermont-Ferrand
ADHD
Ongoing Tai Chi Training for Children With ADHD
Attention Deficit Hyperactivity Disorder (ADHD) has tremendous individual and societal impact, and the effectiveness of current standard treatments is limited.
- Trial name
- NCT03434509
- Testing
- Continuous Tai Chi and Mindful Movement classes
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Williams Syndrome
Motor Deficits and Signal Conduction in Individuals With Williams Syndrome
The current study aims to validate basic research findings of abnormal conductivity and motor abilities from a mouse model in humans.
- Trial name
- NCT05430763
- Where
- Israel
- Sponsor
- Sheba Medical Center
Cognitive Function, Quality of Life
EFFECT OF PERCEPTUAL-MOTOR TRAINING ON COGNITIVE FUNCTIONS, MOTOR ABILITIES AND QUALITY OF LIFE IN CHILDREN WITH ATTENTION DEFICIT HYPERACTIVE DISORDER
This study aims to Determine the effect of perceptual-motor training on: cognitive functions, motor abilities, and quality of life in ADHD children.
- Conditions
- Cognitive Function, Quality of Life, ADHD - Attention Deficit Disorder With Hyperactivity, Motor Abilities
- Trial name
- NCT07139210
- Testing
- perceptual motor training
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Alcohol-related Disorders, Drinking and Driving
Evaluation of an School-based Alcohol Prevention Program for Middle School Students
The purpose of this research is to create and evaluate the efficacy of an exciting (fun to use), and potentially disseminable computer-based prevention program, Click City®: Alcohol, for use by 7th graders with a booster in 8th…
- Conditions
- Alcohol-related Disorders, Drinking and Driving, Neurological Impairment
- Trial name
- AlcoholINET (NCT01847183)
- Testing
- Click City®: Alcohol
- Where
- United States
- Volunteers
- 2,300 people
- Sponsor
- Oregon Research Institute
Attention Deficit Hyperactivity Disorder (ADHD)
Impact of Structured Exercise Programs on Cognitive, Motor and Behavioral Outcomes in Children With ADHD
The purpose of this study is to investigate the effects of structured exercise interventions (Gince Zumba and Square Stepping) on cognitive, motor and behavioral functions of children diagnosed with Attention Deficit…
- Trial name
- ADHD (NCT07376863)
- Testing
- Gince Zumba Exercise, Square Stepping Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Cukurova University
Distorted; Balance, Motor Deficit
Virtual Reality Based Balance Training in People With Mild Cognitive Impairment
The aim of the present study is to evaluate an innovative virtual reality-based balance training intervention for improving clinically relevant motor performances (balance and gait) in people with mild cognitive impairment.
- Conditions
- Distorted; Balance, Motor Deficit, Cognitive Deficit
- Trial name
- NCT02214342
- Testing
- Balance Training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Arizona
Attention Deficit Hyperactivity Disorder (ADHD)
Assessing QbTest Utility in ADHD: A Randomised Controlled Trial
Attention Deficit/Hyperactivity Disorder (ADHD)is one of the most common mental health disorders of childhood. Children with ADHD often have poor attention, are restless and hyperactive and show impulsive behaviour.
- Trial name
- AQUA2 (NCT02209116)
- Testing
- Qb Test
- Where
- 9 sites in United Kingdom
- Volunteers
- 267 people
- Sponsor
- University of Nottingham
ADHD
Lifestyle Enhancement for ADHD Program
The purpose of this study is to investigate if physical activity (PA) can increase in children with Attention Deficit/Hyperactivity Disorder (ADHD) using a modified behavioral management training (BMT) program.
- Trial name
- LEAP (NCT03690674)
- Testing
- Lifestyle Enhancement for ADHD Program
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
Motor Impairments in Children With Autism Spectrum Disorder: a Multimodal Approach
The general goal of the present proposal, Progetto MOSAICO, is the identification of a multimodal panel of neuropsychological, kinematic, neurophysiological, and genetic markers associated with motor abnormalities present in ASD.
- Conditions
- Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder, Intellectual Disability
- Trial name
- MOSAICO (NCT04769011)
- Testing
- Clinical evaluation, Neuropsychological evaluation, Neurophysiological evaluation
- Where
- Italy
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea