Clinical trials: Motor Function
Down Syndrome, Vibration Therapy
Comparative Study of Two Applications on Muscle Strength, Balance and Motor Function in Children With Down Syndrome.
To differentiate between the efficacy of virtual reality and whole-body vibration on muscle strength, balance and motor function in children with down syndrome.
- Conditions
- Down Syndrome, Vibration Therapy, Virtual Reality
- Trial name
- NCT07816120
- Testing
- virtual reality, whole body vibration
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Diplegic Cerebral Palsy
Diplegic Cerebral Palsy and Action Observation Training
In this study, video-based action observation training and live action observation training in children with spastic diplegic cerebral palsy; It was aimed to examine the effect on motor function, activity participation and…
- Trial name
- NCT05209282
- Testing
- Video Based Action Observation, Live Action Observation, Conventional physiotherapy program
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Inonu University
Spinal Muscular Atrophy
A Pilot Study of Biomarkers for Spinal Muscular Atrophy
The goal of this pilot study is to identify a marker or panel of markers in the blood or urine from a wide range of Spinal Muscular Atrophy (SMA) patients that segregates with measures of clinical severity.
- Trial name
- BforSMA (NCT00756821)
- Where
- 18 sites in United States, Canada
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Carelon Research
Parkinson's Disease
EMD 128130 for the Treatment of Parkinson's Disease
This study will evaluate the effects of an experimental drug called EMD 128130 on Parkinson's disease symptoms and on dyskinesias (involuntary movements) that develop as a result of long-term treatment with levodopa.
- Trial name
- NCT00009048
- Testing
- EMD 128130, IV Levodopa
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Alzheimer's Disease
Effects of Group Music Therapy Interventions on Alzheimer's Disease Patients: a Three-arm Randomized Controlled Blind Study.
The purpose of this study is to determine what type of music therapy (active versus passive) approach has higher effects on clinical symptoms in advanced Alzheimer's disease patients
- Trial name
- NCT04761497
- Testing
- Actice music therapy, Watching nature videos, Passive music therapy
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Universidad Católica San Antonio de Murcia
Cerebral Palsy (CP)
Effects of Barefoot vs. Shod Whole Body Vibration Training in Children With Cerebral Palsy
Cerebral palsy (CP) refers to a group of lifelong conditions that affect the development of movement and coordination that lead to activity limitations due to damage to the developing fetal or neonatal brain tissue.
- Trial name
- NCT06596525
- Testing
- Conventional physical therapy, Barefoot Whole Body Vibration Training (WBVTb), Shod Whole Body Vibration Training (WBVTs)
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Trakya University
Alzheimer's Disease, MCI Due to AD
Language, Speech and Motor Function in MCI Due to AD and Alzheimer's Disease
The goal of this observational cross-sectional study is to explore the characteristics of language, speech, and motor function in persons with Mild Cognitive Impairment due to Alzheimer's disease ("MCI due to AD") and persons…
- Conditions
- Alzheimer's Disease, MCI Due to AD, Dementia Alzheimers
- Trial name
- NCT06508268
- Testing
- GAITRite walkway system OR 4-meter walking speed test, Jamar hand dynamometer, Picture description task
- Where
- Netherlands
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Hanze University of Applied Sciences Groningen
Pelvic Floor Disorders, Lower Urinary Tract Symptoms
Respiratory and Pelvic Floor Muscle Functions of Children With Lower Urinary Tract Dysfunction
Lower urinary tract dysfunctions (LUTD) are disorders that can occur in the storage and voiding stages of bladder function other than neurological disease or lower urinary tract obstruction.
- Conditions
- Pelvic Floor Disorders, Lower Urinary Tract Symptoms, Physical Activity
- Trial name
- NCT06728540
- Testing
- Investigation of Physical Activity Levels, Respiratory and Pelvic Floor Muscle Function
- Where
- Turkey (Türkiye)
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Seda Yakit Yesilyurt
Cerebral Palsy, Developmental Coordination Disorder
Bootle Blast: Understanding the Family Experience
One in 60 children have a physical disability that can impact activities and participation. Occupational and physical therapies can be of great benefit, but are costly and difficult to access.
- Conditions
- Cerebral Palsy, Developmental Coordination Disorder, Developmental Disability, Autism Spectrum Disorder
- Trial name
- NCT06161168
- Testing
- Bootle Blast Play Phase (B)
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Cerebral Palsy (CP)
Effects of Motor Imagery and Action Observation on Motor Function in Unilateral Cerebral Palsy
The aim of this study is to evaluate the effects of action observation therapy and motor imagery methods, provided in addition to a conventional physiotherapy and rehabilitation program, on gross motor function, upper and lower…
- Trial name
- NCT07612371
- Testing
- motor imagery, Action observation therapy, Conventional physiotherapy group
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Bahçeşehir University
Spina Bifida
Motor Imagery-Supported Thoracic Expansion in Children With Spina Bifida
This study will investigate whether adding motor imagery to thoracic expansion exercises can improve respiratory function in children with spina bifida.
- Trial name
- NCT07846202
- Testing
- Thoracic Expansion Exercises, Motor Imagery-Supported Thoracic Expansion Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Karabuk University
Cerebral Palsy
Effect of a New Interactive Device on the Motor and Functional Abilities of Children With Bilateral Cerebral Palsy
Recent research has shown that interventions with assistive technologies lead to an improvement in the motor and functional abilities of children with cerebral palsy (CP).
- Trial name
- NCT04403464
- Testing
- HABIT-ILE with REAtouch®, HABIT-ILE without REAtouch®
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Université Catholique de Louvain
Down Syndrome
Neurodevelopmental Treatment for Balance and Mobility in Children With Down Syndrome
The goal of this clinical trial is to evaluate whether Neurodevelopmental Treatment (NDT) can improve balance, mobility, walking capacity, and functional independence in preschool children with Down syndrome.
- Trial name
- NCT07653399
- Testing
- Neurodevelopmental Treatment (NDT)
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Istanbul Nisantasi University
Gross Motor Development Delay, Cerebral Palsy
Small Step Intervention for Infants With Cerebral Palsy and Other Neurodevelopmental Disorders
Children with cerebral palsy (CP) have life-long motor disorders and are typically subjected to extensive treatment throughout childhood.
- Trial name
- smallstep (NCT02166801)
- Testing
- Early intervention for infants, usual care
- Where
- Sweden
- Volunteers
- 39 people
- Sponsor
- Karolinska Institutet
Cerebral Palsy (CP), Rehabilitation
Trial Examines Short-term Effects of Hippotherapy on Fascia Properties and Quality of Life in Children With CP.
The effects of hippotherapy on gross motor function, balance, and spasticity in children with cerebral palsy (CP) are well-documented, but its impact on the thoracolumbar fascia (TLF) remains unexplored area to date.
- Conditions
- Cerebral Palsy (CP), Rehabilitation, Motor Coordination or Function, Hippotherapy
- Trial name
- HYPPOTER25 (NCT07134582)
- Testing
- Hippotherapy 1x/week, Hippotherapy 2x/week
- Where
- Slovenia
- Volunteers
- 27 people
- Sponsor
- University Medical Centre Ljubljana
Atherosclerosis, Heart Failure, Congestive
The Role of Angiotensin Type I Receptor in the Regulation of Human Coronary Vascular Function
The renin angiotensin system (RAS) plays an important physiological and pathophysiological role in the control of blood pressure and plasma volume.
- Conditions
- Atherosclerosis, Heart Failure, Congestive, Hypertension, Myocardial Infarction
- Trial name
- NCT00001629
- Testing
- Angiotensin II type 1 receptor antagonists
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Thalassemia
Effect of Exercise on Body Composition and Bone Health in Patients With Thalassemia
The goal of this clinical trial is to determine if a weight bearing exercise intervention can improve body composition and bone health in adolescents and adults with Thalassemia.
- Trial name
- NCT07064941
- Testing
- Exercise
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Autism
Oxcarbazepine Versus Placebo in Childhood Autism
The proposed study is designed to assess the effectiveness of treatment with Oxcarbazepine vs. placebo in childhood/adolescent autism.
- Trial name
- NCT00467753
- Testing
- Oxcarbazepine
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Spinal Muscular Atrophy Type I
Impact of Motor and Oral Motor Function on Quality of Life in Children With SMA
The aim of this study is to investigate the impact of motor and oral motor functions on the quality of life in children aged 2-4 years diagnosed with Spinal Muscular Atrophy (SMA) Type I.
- Trial name
- NCT06864767
- Testing
- Neuro-sensory Motor Developmental Assessment, Functional Oral Intake Scale, Behavioral Pediatrics Feeding Assessment Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people
- Sponsor
- Zeynep HOŞBAY
Diplegic Cerebral Palsy
Effect of Sensory Integration in Diplegic Cerebral Palsy
The purpose of this study is to compare the effects of sensory integration therapy (SIT) applied in addition to neurodevelopmental treatment (NDT) on Motor Function, Balance, and Trunk Control in diplegia cerebral palsy
- Trial name
- NCT06462859
- Testing
- Sensory Integration Therapy Group, Neurodevelopmental Treatment Group
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Halic University