Clinical trials: Movement Disorder
ALS, Autism Spectrum Disorder
Pharmacokinetic (PK) and Pharmacodynamics (PD) Study of Ilera Specific Products
This is an observational study of medical marijuana manufactured and dispensed by Ilera and given as standard treatment for a variety of approved serious medical conditions as defined by individual state law.
- Conditions
- ALS, Autism Spectrum Disorder, Cancer, Spasticity, Muscle
- Trial name
- Ilera (NCT03886753)
- Testing
- Registry, PK microsampling of blood
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital of Philadelphia
Huntington Disease
Transcranial Static Magnetic Stimulation (tSMS) in Huntington's Disease (HD)
Huntington's disease (HD) is a neurodegenerative pathology characterized by choreic hyperkinesias which represent the typical motor symptom and are represented by involuntary, aimless, irregular, recurrent, unpredictable and…
- Trial name
- NCT06976983
- Testing
- Portable ergonomic helmet for real tSMS
- Volunteers
- 30 people
- Sponsor
- Neuromed IRCCS
Traumatic Brain Injury, Cerebral Palsy
Real World Outcomes of Intranasal MuSE Exosomes and Stem Cells in Neurological Regenerative Therapy
This prospective observational study collects real world data on participants receiving regenerative therapies administered internationally and delivered intranasally via the Kurve Therapeutics ViaNase device.
- Conditions
- Traumatic Brain Injury, Cerebral Palsy, Hypoxic Ischemic Encephalopathy, Neurologic Disorders
- Trial name
- MuSE-INSIGHT (NCT07521384)
- Where
- Mexico
- Volunteers
- 36 people
- Sponsor
- Healing Hope International
Focal Dystonia
Survey of Sensory and Motor Tricks in Focal Dystonia
This study will collect information on (tricks) patients with focal dystonia use to relieve their symptoms. Dystonia is a movement disorder caused by sustained muscle contractions often causing twisting and abnormal posturing.
- Trial name
- NCT00054652
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Tourette Syndrome
Thalamic Deep Brain Stimulation for the Treatment of Refractory Tourette Syndrome
This research is being performed to try to understand if the use of deep brain stimulation or DBS can treat the symptoms of Tourette syndrome that do not respond well to current medications.
- Trial name
- NCT01817517
- Testing
- Medtronic Activa Deep Brain Stimulation System
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Johns Hopkins University
Cerebral Palsy
Smartphone App for Analysis of General Movements in Young Infants
Analysis of spontaneous movements in young infants from video recordings is recommended as an early medical assessment tool for prediction of cerebral palsy in high-risk infants.
- Trial name
- NCT03409978
- Testing
- in-Motion app
- Where
- 3 sites in Belgium, Denmark and 1 more
- Volunteers
- 86 people
- Sponsor
- St. Olavs Hospital
Parkinson's Disease, Magnetic Resonance Imaging
Predictive Value of Multimodal MRI in Parkinson's Disease
Deep brain stimulation (DBS) is recognized as the most safe and effective neurosurgical method for the treatment of advanced Parkinson's disease.
- Conditions
- Parkinson's Disease, Magnetic Resonance Imaging, Deep Brain Stimulation
- Trial name
- NCT05003206
- Testing
- Functional magnetic resonance imaging, Deep Brain Stimulation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chinese PLA General Hospital
Obesity
Movement Therapy and Childhood Obesity
The Child health and Sports Center, Meir Medical Center, has an intervention program to treat obese children. The program includes physical activity, nutritional intervention and behavioral treatment.The emphasis given in the…
- Trial name
- NCT01555034
- Testing
- movement therapy, exercise plus nutrition
- Where
- Israel
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Spastic Cerebral Palsy (sCP)
Talocrural Mobilization With Movement in Spastic Cerebral Palsy
The aim of this randomized controlled trial is to find the effect of Mulligan's Mobilization with Movement of Talocrural joint in Cerebral Palsy Patients having spasticity on improving Ankle Range of Motion, improving balance and…
- Trial name
- NCT06598657
- Testing
- Mobilization with Movement MWM, Conventional Treatment
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Angelman Syndrome
A Study to Investigate the Pharmacokinetics (PK) and Safety and to Provide Proof of Mechanism of Alogabat in Children and Adolescents Aged 5-17 Years With Angelman Syndrome (AS) With Deletion Genotype.
This is a two-part, Phase IIa, multicenter, 12-week, open-label study. Up to 56 participants with deletion AS aged 5-17 years (inclusive) will be enrolled in the study.
- Trial name
- Aldebaran (NCT05630066)
- Testing
- Alogabat
- Where
- 19 sites in United States, Australia and 4 more
- Volunteers
- 48 people
- Sponsor
- Hoffmann-La Roche
Parkinson's Disease
Deep Brain Stimulation of the Subthalamic Nucleus (STN) and Cognitive Control
In this study, the investigators will follow patients who have had stimulators implanted, at their usual clinic follow-up appointments 3, 6, 9 and 12 months after surgery.
- Trial name
- COVOLT (NCT00917722)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Washington University School of Medicine
Tic-Disorder
Efficacy of a Habit Reversal Treatment on Tic-symptoms
The main purpose of this study is to evaluate the efficacy of a habit reversal based treatment programme in children and adolescents aged 8 to 18 years with tic disorders.
- Trial name
- NCT02190383
- Testing
- Habit Reversal Training
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University of Cologne
Focal Dystonia
Motor Training to Treat Hand Dystonia
This study will evaluate the effect of motor training on focal hand dystonia in people with writer's cramp and will examine whether this training affects excitability of the motor cortex of the brain.
- Trial name
- NCT00021853
- Testing
- constraint-induced movement therapy
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Virtual Buddy Movement Therapy for Psychomotor and Social Development in Pediatric Oncology Patients in Remission
Acute lymphoblastic leukemia is the most common type of cancer in children diagnosed between the ages of two and five. After cancer treatment, children suffer from fatigue and exhaustion, and thus a decrease in daily physical…
- Trial name
- NCT07522905
- Testing
- Virtual BUDDY-Movement Therapy
- Where
- Slovakia
- Volunteers
- 24 people
- Sponsor
- Comenius University
Knee Injuries, Ankle Injuries and Disorders
The Association Between Restricted Ankle Joint Dorsiflexion and Dynamic Knee Valgus
The purpose of this study was to analyze if a low ankle dorsiflexion range is associate with dynamic knee valgus in youth basketball players.
- Conditions
- Knee Injuries, Ankle Injuries and Disorders, Movement, Abnormal, Adolescent Development
- Trial name
- TOBROD (NCT05500131)
- Testing
- Observation
- Where
- Spain
- Volunteers
- 791 people
- Sponsor
- University Rovira i Virgili
Parkinson's Disease
ADAGIO Follow Up Study: Evaluation of the Long-Term Effects of Rasagiline in Parkinson's Disease Subjects
Eligible participants, who participated in the ADAGIO trial and who sign an approved informed consent form, will be enrolled into the study at their original study locations.
- Trial name
- NCT00936676
- Testing
- rasagiline mesylate
- Where
- 102 sites in United States, Argentina and 11 more
- Volunteers
- 684 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Hemiplegia, Infantile
Movement in the Non-use of the Affected Upper Extremity in Children Hemiparesis: Mirror Therapy and Action-observation
Children with cerebral palsy hemiplegia present a restriction in the daily activities due to the limitation in the active movement of the affected upper extremity.
- Trial name
- NCT04284176
- Testing
- Mirror therapy and action-observation therapy
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- CEU San Pablo University
Cerebral Palsy
Comparative Effect of CIMT and PNFTechnique on Hands Dexterity in Cerebral Palsy
Cerebral Palsy (CP) is a group of permanent disorders of the development of movement and posture, causing activity limitations that are attributed to non-progressive disturbances that occurred in the developing fetal or infant…
- Trial name
- NCT07673289
- Testing
- Constraint-Induced Movement Therapy, Proprioceptive Neuromuscular Facilitation Therapy
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Malocclusion, Angle Class II, Retrognathism
The Effect of Functional Treatment of Patients With Backward Positioned Chins on the Jaw Joint and Movements
Patients with class II malocclusion and retrognathic mandibles will be treated using functional appliances and asses the remodeling that is expected to occur in the temporomandibular joint (TMJ) using cone-beam computed…
- Conditions
- Malocclusion, Angle Class II, Retrognathism, TMJ
- Trial name
- NCT03645343
- Testing
- Activator, Twin Block
- Where
- Syria
- Volunteers
- 66 people
- Sponsor
- Damascus University
Parkinson's Disease, Deep Brain Stimulation
Can Subthalamic Stimulation Using Directional Electrodes Improve Postoperative Management in Parkinson's Disease
The primary objective of the study is to determine if subthalamic nucleus (STN) deep brain stimulation (DBS) using the Vercise directional leads improves neuropsychiatric state and neuropsychiatric fluctuations 12 months after…
- Trial name
- Steeropt (NCT04578678)
- Testing
- Steering
- Where
- 4 sites in France, Germany and 1 more
- Volunteers
- 105 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
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