Clinical trials: Movement Disorder
Angelman Syndrome
CHAMPION: A Study to Evaluate the Efficacy and Safety of Obudanersen (ION582) in Children and Adults With Angelman Syndrome (AS)
The primary purpose of the study is to evaluate efficacy of obudanersen in participants with AS due to uniparental disomy or imprinting defects (UPD/ID) as measured through expressive communication.
- Trial name
- NCT07782827
- Testing
- obudanersen
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Ionis Pharmaceuticals, Inc.
Tourette Syndrome, Tourette Syndrome in Children
Tourette Discrimination (TD) Stigma Scale
The goal of this qualitative study is to understand the challenges of stigmatization and discrimination in children and young adults with Chronic Tic Disorders (CTD), including Tourette Syndrome.
- Conditions
- Tourette Syndrome, Tourette Syndrome in Children, Tourette Syndrome in Adolescence, Tic Disorder, Childhood
- Trial name
- TD (NCT05696769)
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Wake Forest University Health Sciences
Wilson Disease
Evaluation of Cognitive Dysfunction and Psychiatric Comorbidities
Primary objective Collection of patients with wilson disease either presented with neurological or hepatic symptoms Assessment of psychiatric and cognitive disorders in both groups by using specific scales Secondary objective…
- Trial name
- NCT06179394
- Volunteers
- 40 people
- Sponsor
- Assiut University
Cerebral Palsy
Comparison of Constraint-Induced Movement Therapy And Bimanual Intensive Therapy Through Tele-rehabilitation For CP
Cerebral palsy is a neurological condition affecting movement and posture, caused by non-progressive brain disruptions occurring during fetal development.
- Trial name
- NCT06658275
- Testing
- Constraint-induced movement therapy, Hand Arm Bimanual Intensive Training -HABIT
- Volunteers
- 65 people
- Sponsor
- Riphah International University
Parkinson Disease, Executive Dysfunction
Effect of Computer-based Cognitive Training on Attention and Executive Functions in Patients With Parkinson's Disease
The current study adresses the effect of two different computer-based cognitive trianing programmes on attention and executive functions in patients with Parkinson's disease.
- Trial name
- NCT03285347
- Testing
- Computer-based cognitive training
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Bispebjerg Hospital
Wilson's Disease
International Wilson's Disease Patient Registry (iWilson Registry)
Longitudinal, observational, non-interventional, standard of care Registry. Data will be collected from the routinely scheduled WD clinic visits at approximately 6-12 month intervals.
- Trial name
- NCT05239858
- Where
- 16 sites in Belgium, France and 5 more
- Volunteers
- 500 people
- Sponsor
- Orphalan
Hemiplegic Cerebral Palsy
Comparison of CIMT and Its Modified Form on Upper Motor Function Outcomes in Hemiplegic Cerebral Palsy.
The aim of this research is to compare the effect of classic constraint-induced movement therapy and its modified form on upper extremity motor function outcomes and psychosocial impact in hemiplegic cerebral palsy.
- Trial name
- CIMT (NCT03691506)
- Testing
- Classic CIMT group, Modified CIMT group
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Juvenile Huntington Disease, Juvenile-Onset Huntington Disease
Longitudinal Assessment of Brain Structure and Function in Juvenile-onset Huntington's Disease
The goal of this observational study is to learn about brain development in Juvenile-onset Huntington's Disease (JoHD). The main questions it aims to answer are: Is brain development different in JoHD than Adult-onset…
- Trial name
- NCT05707663
- Where
- 5 sites in United States
- Volunteers
- 37 people
- Sponsor
- University of Iowa
Parkinson Disease
Prebiotics in the Parkinson's Disease Microbiome
There are about one million Parkinson's disease (PD) patients in America. The risks associated with whether or not an individual may develop PD include environment and genetic (biologic, hereditary) factors.
- Trial name
- NCT04512599
- Testing
- Prebiotic Bar
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Rush University Medical Center
Tourette Disorder, Tic Disorders
Evaluating the Efficacy and Safety of Yi-Gan San in Children and Adolescents With Tourette's Disorder
Yigansan was used in Ming dynasty by Xue Kai as a remedy for restlessness and agitation in children. We expect that the total YGTSS scores of Yigansan-treated subjects will be significantly reduced compared to that of…
- Trial name
- NCT03564132
- Testing
- Yigansan
- Where
- Taiwan
- Volunteers
- 38 people
- Sponsor
- China Medical University Hospital
Parkinson Disease
The Effect of Intranasal Insulin on Motor and Non-motor Symptoms in Parkinson's Disease Patients
This study will evaluate the effect of intranasal insulin on motor and non-motor symptoms of patients with Parkinson's disease over a 12-week period.
- Trial name
- NCT04687878
- Testing
- Insulin, Normal saline
- Where
- Iran
- Volunteers
- 28 people
- Sponsor
- dr.dargahi
Cerebral Palsy, Premature Birth
Early Movements as a Predictor of Future Developmental Delay
Cerebral Palsy (CP) is a major developmental problem. Major risk groups of CP, are preterm infants and multiple pregnancies. Previous studies using the General Movements methodology demonstrated early identification of CP, as…
- Trial name
- NCT00418808
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Sheba Medical Center
Parkinson's Disease
Ambulatory Assessment of Motor State in Patients With Parkinson's Disease in Real Daily Life
Patients with Parkinson's disease (PD) suffer from motor fluctuations and levodopa induced dyskinesia. The prupose of this study is to evaluate the effect of an automatic system to assess the motor state of PD patients in real…
- Trial name
- NCT00184808
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- Radboud University Medical Center
Cerebral Palsy
Effectiveness of the Wheelchair Skills Training Program in People With Complex Movement Disorders
The overall goal of this project is to increase independent mobility in populations with complex movement disorders, such as severe cerebral palsy, by adapting The Wheelchair Skills Training Program (WSTP) to the needs and…
- Trial name
- NCT05293093
- Testing
- Wheelchair Skills Training Program
- Where
- Belgium
- Volunteers
- 12 people
- Sponsor
- KU Leuven
Parkinson's Disease
Medication Review in Patients on Anti-parkinson Therapy
To identify patients within the community taking anti-parkinson medications in whom the diagnosis of Parkinson's disease is incorrect and to supervise and clinically monitor the withdrawal of anti-parkinson medications in this…
- Trial name
- PDCom (NCT00443768)
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- South Glasgow University Hospitals NHS Trust
Oppositional Defiant Disorder, Conduct Disorder
Study to Determine Whether There Are Any Cognitive or Motor Effects From Taking the Medicine Risperidone.
This study was developed in order to assess the effects of risperidone (Risperdal) as compared with placebo on cognitive-motor performance (attention, memory, and hand steadiness) and body movements.
- Conditions
- Oppositional Defiant Disorder, Conduct Disorder, Attention Deficit/Hyperactivity Disorder (ADHD), Intermittent Explosive Disorder
- Trial name
- NCT00399698
- Testing
- Risperdal
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Ohio State University
Parkinson Disease
Effects of an Independent Walking Program With Walking Poles in People With Parkinson Disease
Study Purpose: The purpose of the study is to compare changes in activity levels and walking in people with Parkinson disease after an 8-week independent walking program with or without using walking poles.
- Trial name
- ActivatePD (NCT06908135)
- Testing
- Independent walking program using walking poles, Independent walking program without walking poles
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Pacific Northwest University of Health Sciences
Obstructive Sleep Apnea, Orthodontic Tooth Movement
The Effect of Tooth Position During Orthodontic Treatment on the Apnea/ Hypopnea Index (AHI)
The study design of this research project involves orthodontic patients registered at the Harvard School of Dental Medicine who are deemed eligible to undergo orthodontic treatment and who have been provided with sufficient…
- Conditions
- Obstructive Sleep Apnea, Orthodontic Tooth Movement, Apnea, Sleep Disordered Breathing
- Trial name
- NCT03299023
- Testing
- Medibyte Portable Monitor
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Harvard School of Dental Medicine
Parkinson's Disease
Managing Changes in Life After Deep Brain Stimulation for Parkinson's Disease
Parkinson's disease is a chronic progressive neurological disorder. Symptoms are tremor, slowness in movement, rigidity and postural instability.
- Trial name
- NCT01681641
- Testing
- A psycho-social intervention
- Where
- 3 sites in Denmark
- Volunteers
- 32 people
- Sponsor
- University of Aarhus
Tourettes Syndrome, Tic
N-acetylcysteine (NAC) for Children With Tourette Syndrome
Tourette syndrome is a childhood-onset neuropsychiatric disorder characterized by multiple motor and vocal tics that last for at least a year in duration.
- Trial name
- NCT01172288
- Testing
- N-Acetylcysteine (NAC)
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Yale University
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