Clinical trials: Movement Disorders
Cerebral Palsy
Piloting Home-based Movement-to-Music Among Adolescents With Cerebral Palsy: A Randomized Controlled Trial
This study pilots the efficacy of a home-based movement-to-music program for increasing physical activity participation among adolescents with cerebral palsy.
- Trial name
- M2MCP (NCT04264390)
- Testing
- Movement-to-music
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- University of Alabama at Birmingham
Nystagmus
Eye Muscle Surgery to Treat Congenital Nystagmus
This study will examine the safety and effectiveness of a new surgical procedure to correct congenital nystagmus-a disorder of eye muscle-vision-brain coordination characterized by rapid to and fro eye movements (oscillation).
- Trial name
- NCT00001866
- Testing
- horizontal muscles of the eye will be cut and then reattached in the same position
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- National Eye Institute (NEI)
Trientine Treatment for Wilson's Disease
A Retrospective Study to Assess the Clinical Efficacy and Safety of Trientine in Wilson's Disease Patients
This is a retrospective study to assess the clinical efficacy and safety of trientine in Wilson's disease patients
- Trial name
- NCT03299829
- Testing
- Trientine
- Where
- Taiwan
- Volunteers
- 48 people
- Sponsor
- Excelsior
Shoulder Pain
The Effect of a Shoulder Training Program to Prevent Shoulder Pain Among Girls in Junior Team Handball
Very little is known about the potential for preventing the prevalence of shoulder complaints in handball players, particularly younger players.
- Trial name
- NCT02631395
- Testing
- Exercise, Control group
- Volunteers
- 106 people
- Sponsor
- Norwegian University of Science and Technology
CP (Cerebral Palsy)
Tolerance of a Motorized Orthosis Reproducing Walking Movement vs Conventional Standing-up Devices in Child With CP
Cerebral palsy (CP) includes all the sensorimotor development disorders leading to balance, gait and movement disruptions. These disorders are related to lesions of the central nervous system (CNS) that occurs at birth or during…
- Trial name
- EOMEC/CP (NCT02669160)
- Testing
- PC Innowalk, Conventional passive stander
- Where
- 4 sites in France
- Volunteers
- 25 people
- Sponsor
- Lille Catholic University
Parkinson's Disease
Feasibility Study to Evaluate Deep Brain Stimulation (DBS) Settings for the Treatment of Parkinson's Disease
The purpose of this study is to assess the cognitive performance in patients with advanced Parkinson's disease receiving Deep Brain Stimulation (DBS) with settings predetermined clinically to settings derived from a…
- Trial name
- SAGE (NCT01230151)
- Testing
- GUIDE software, Version 0.1, Clinically defined stimulation parameters
- Where
- 4 sites in United States
- Volunteers
- 80 people
- Sponsor
- Intelect Medical, Inc.
Tourette Syndrome
Safety and Efficacy Study of NBI-98854 in Children and Adolescents With Tourette Syndrome
Phase 2, double-blind, placebo-controlled study to assess the safety and efficacy of NBI-98854 administered once daily (qd) for a total of 6 weeks of treatment.
- Trial name
- NCT02679079
- Testing
- NBI-98854
- Where
- 44 sites in United States
- Volunteers
- 98 people
- Sponsor
- Neurocrine Biosciences
Inherited Movement Disorders, Spinocerebellar Ataxias
Biomarker Research in Inherited Movement Disorders
Inherited movement disorders are rare conditions, whose cumulative prevalence are in the order of 5-10/100,000 inhabitants, in most cases progressive and can lead to a significant loss of autonomy after one or more decades of…
- Conditions
- Inherited Movement Disorders, Spinocerebellar Ataxias, Hyperkinetic Disorders
- Trial name
- BIOMOV (NCT05034172)
- Testing
- Clinical follow-up
- Where
- France
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Epilepsy in Children, Dyskinesias
A Retrospective Survey-based Multicenter Study to Delineate the Molecular and Phenotypic Spectrum of Epilepsy-dyskinesia Syndromes
The Epilepsy-Dyskinesia Study aims to advance the understanding of the clinical and molecular spectrum of epilepsy-dyskinesia syndromes, monogenic diseases that cause both movement disorders and epilepsy.
- Conditions
- Epilepsy in Children, Dyskinesias, Movement Disorders in Children, Neurologic Disorder
- Trial name
- NCT06585605
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Boston Children's Hospital
Epilepsy, Generalized, Absence Epilepsy
Detecting Absence Seizures Using Eye Tracking
The goal of this study is to develop a comfortable system that uses a wearable eye-tracker similar to eyeglasses to assist people with epilepsy in counting and measuring the severity of seizures.
- Conditions
- Epilepsy, Generalized, Absence Epilepsy, Absence Seizures, Seizures
- Trial name
- NCT04439656
- Testing
- Eye movement analysis
- Where
- 5 sites in United States
- Volunteers
- 150 people
- Sponsor
- Rachel Kuperman
Parkinson Disease
PF 06412562 in Subjects With Advanced Stage Parkinson's Disease
The purpose of this study is to test the safety and tolerability of the investigational drug PF-06412562 compared to the current medical standard of care medication for Parkinson's disease, carbidopa/levodopa.
- Trial name
- NCT03665454
- Testing
- PF-06412562
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Milton S. Hershey Medical Center
Schizophrenia, Negative Symptoms in Schizophrenia
Dance and Movement Therapy in Patients With Schizophrenia
Introduction: Schizophrenia is a mental disorder that starts at a young age and progresses with positive (hallucination, delusion) and negative (decreased emotional participation, reluctance) symptoms.
- Conditions
- Schizophrenia, Negative Symptoms in Schizophrenia, Disabilities Mental, Dance Therapy
- Trial name
- DMTinSchizo (NCT05500651)
- Testing
- Dance and Movement Therapy (DMT)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Amasya University
Angelman Syndrome, Fragile X Syndrome
Single Dose Pharmacokinetic (PK) Study
The trial is a Phase 1 Single Dose PK Study in Adolescent Subjects with Fragile X syndrome (FXS) or Angelman syndrome (AS). The primary objective of the study is to evaluate the pharmacokinetics (PK) of OV101 following a single 5…
- Trial name
- NCT03109756
- Testing
- OV101
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Ovid Therapeutics Inc.
Intellectual Disability, Rubinstein-Taybi Syndrome
Functional Tests to Resolve Unsolved Rare Diseases. Rares.
Rares diseases are a heterogeneous group of conditions which need important tools for diagnosis. The use of high-throughput sequencing is able to diagnose half of the patients.
- Conditions
- Intellectual Disability, Rubinstein-Taybi Syndrome, Cystic Fibrosis, Congenital Heart Defect
- Trial name
- RID (NCT05696912)
- Testing
- Ex-vivo approach concerning 25 patients, In-vitro approach concerning 25 patients
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Bordeaux
Child Development Disorder
Effects of CIMT With and Without Robotic Gloves in Children With Hemiplegic CP
This study investigates the impact of CIMT, with and without robotic gloves, on hand dexterity and grip strength in children with hemiplegic CP, aiming to enhance motor skills and promote independence in daily activities.
- Trial name
- NCT07248735
- Testing
- CIMT with robotic glove, CIMT with standard rehabilitation
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Tourette Syndrome, Behavioral Problem
Parent Behavioral Training for Disruptive Behaviors in Tourette Syndrome
This is a randomized controlled trial to assess the efficacy of a parent training program to control disruptive behaviors in children with Tourette Syndrome.
- Trial name
- NCT02882490
- Testing
- Parent Training, Supportive Therapy
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Hospital Clinic of Barcelona
Parkinson Disease
Learning Potential of Patients With Parkinson's Disease After Two Weeks of Targeted Touchscreen Training
Parkinson's disease (PD) is characterized by severe motor and non-motor symptoms, including upper limb dysfunction. Due to the degradation of dopaminergic neurons in the striatum, PD patients experience difficulties with motor…
- Trial name
- NCT05696197
- Testing
- Targeted touchscreen training
- Where
- Belgium
- Volunteers
- 36 people
- Sponsor
- KU Leuven
Acute Lymphobkastic Leukemia, Medication Adherence
The AYA Oncology Self-care Movement
This trial will test the impact of a social media intervention for improving oral chemotherapy adherence among adolescents and young adults (AYAs) with acute lymphoblastic leukemia.
- Trial name
- #AYAOSM (NCT07724652)
- Testing
- Educational Website, #AYAOSM
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Northwestern University
PTSD, Depression
Arts and Movement Therapies for Trauma
The current goal of this project is to subjectively and objectively assess the efficacy of arts and movement interventions--including dance/movement therapy, art therapy and mindful yoga for youth and adults exposed to trauma…
- Conditions
- PTSD, Depression, Anxiety, Stress
- Trial name
- NCT03515564
- Testing
- Dance/Movement Therapy, Art Therapy, Mindful Yoga
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- Wayne State University
Creation of an Italian Network of Biobanks of Rare Diseases
ScATtEred Rare Disease Biobanks: a Model of Sample/Data Collection With susTainablE and Shared Criteria
Rare diseases (RDs) have been defined by the European Union (EU) as life-threatening or chronically debilitating conditions affecting less than 1 person in 2000.
- Trial name
- SATELLITES (NCT06782230)
- Where
- Italy
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- IRCCS Policlinico S. Donato
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