Clinical trials: Movement Disorders
Myopia
Wearing Behavior and Eye Length Changes in Children With Myopia Wearing Myopia Control Spectacle Lenses
The goal of this clinical trial is to learn how children with myopia aged 8 to 15 years move their eyes and heads during near-vision tasks while wearing different spectacle lenses, and if wearing myopia control spectacle lenses…
- Trial name
- NCT07780851
- Testing
- Single Vision Lens (SVL), Myopia Control Lens (MCL)
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- Essilor International
Angelman Syndrome
A Study of the Safety and Tolerability of GTX-102 in Children With Angelman Syndrome
The primary objective of the study is to evaluate the safety and tolerability of multiple-ascending doses of GTX-102 administered by intrathecal (IT) injection to participants with Angelman Syndrome (AS).
- Trial name
- NCT04259281
- Testing
- GTX-102
- Where
- 25 sites in United States, Australia and 6 more
- Volunteers
- 74 people
- Sponsor
- Ultragenyx Pharmaceutical Inc
Pelvic Organ Prolapse, Constipation
Cohort Study of Bowel Function Following Robotic-assisted Laparoscopic Sacrocolpopexy
Compare changes in bowel function before, 6 months and one year after Robotic-assisted laparoscopic sacral colpopexy. Compare objective anatomic outcomes before, 6 months and one year after Robotic-assisted laparoscopic sacral…
- Conditions
- Pelvic Organ Prolapse, Constipation, Bowel Dysfunction, Irritable Bowel Syndrome
- Trial name
- NCT01618292
- Testing
- Robotic sacral colpopexy
- Where
- United States
- Volunteers
- 393 people
- Sponsor
- Atlantic Health System
Cerebral Palsy, Hemiplegic Cerebral Palsy
Implementation of Therapy Together
The goal of this clinical trial is to learn about the implementation of Therapy Together, a pediatric constraint-induced movement therapy program in young children with unilateral cerebral palsy.
- Trial name
- NCT06040619
- Testing
- Therapy Together, Usual Care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Texas Scottish Rite Hospital for Children
Cerebral Palsy (CP)
Feasibility and Discriminant Validity of Monitoring Movement Behavior of Adolescents With Cerebral Palsy
A new artificial intelligence network has been developed to monitor real-world daytime and nighttime movement behavior of adolescents with cerebral palsy (CP).
- Trial name
- NCT06090383
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Spinal Muscular Atrophy
Holter of Movement in Patients with SMA Undergoing Treatment.
Acti-SMA is a multi-centric academic study. It aims to monitor the progress of patients with spinal muscular atrophy under treatment with Spinraza° or risdiplam.
- Trial name
- NCT04888702
- Testing
- Actimyo
- Where
- 3 sites in Belgium, Romania
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Liege
Movement Disorders, Muscle Tone
Massage and Cold Water Immersion on Movement Variability After Fatigue in Swimmers
The goal of this clinical trial is to investigate the effectiveness of post-exercise massage and cold-water immersion compared to control in young elite swimmers.
- Conditions
- Movement Disorders, Muscle Tone, Perceived Exertion
- Trial name
- NCT04541901
- Testing
- Massage, Cold water immersion
- Where
- Brazil
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Flávia Carvalho
Tourette Syndrome
Pilot Study of the Modified Atkins Diet for Tourette Syndrome
Pharmacotherapy has long been considered the primary approach for tic suppression in Tourette syndrome (TS). Unfortunately, medications are often ineffective and frequently have significant side-effects.
- Trial name
- NCT00952601
- Testing
- Modified Atkins diet
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
Nursing Education
PechaKucha Versus PowerPoint for Parkinson's Disease Education in Nurses
This study compared the effects of PechaKucha and traditional PowerPoint presentation techniques used for Parkinson's disease education on nurses' knowledge and awareness levels.
- Trial name
- NCT07800312
- Testing
- PechaKucha-Based Parkinson's Disease Education, PowerPoint-Based Parkinson's Disease Education
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Parkinson Disease
Algorithm Guided DBS Programming in Parkinson's Patients
Patients undergoing Deep Brain Stimulation for Parkinson's disease will be subjected to standard of care programming and compared with the algorithm based programming (StimSearch).
- Trial name
- NCT06205043
- Testing
- StimSearch programming algorithm software, Clinician based programming
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Jaslok Hospital and Research Centre
Demyelinating Disease, Healthy
Magnetic Stimulation of the Human Nervous System
Transcranial Magnetic Stimulation (TMS) is a non-invasive technique to gather information about brain function. It is very useful when studying the areas of the brain related to motor activity (motor cortex, corticospinal tract…
- Conditions
- Demyelinating Disease, Healthy, Lysosomal Storage Disease, Motor Neuron Disease
- Trial name
- NCT00001780
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cerebral Palsy
Piloting Home-based Movement-to-Music Among Adolescents With Cerebral Palsy: A Randomized Controlled Trial
This study pilots the efficacy of a home-based movement-to-music program for increasing physical activity participation among adolescents with cerebral palsy.
- Trial name
- M2MCP (NCT04264390)
- Testing
- Movement-to-music
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- University of Alabama at Birmingham
Parkinson Disease, Deep Brain Stimulation
Validation of HaGuide Software Module Accuracy in Mapping STN Boundaries in Parkinson's Disease Patients Who Underwent DBS Procedure
HaGuide version 1.0 (Neuro-Omega Ltd.) is a software module add-on to the FDA cleared Neuro-Omega System (K123796). It was designed to facilitate the use of Neuro-Omega's system by automatically mapping visually the depth of STN…
- Trial name
- NCT03363724
- Testing
- HaGuide version 1.0 software module
- Volunteers
- 103 people
- Sponsor
- Alpha Omega Engineering Ltd.
Intellectual Disability
Effects of Adaptive Physical Activity on Health-related Fitness of Students With Intellectual Disabilitiesdisability
The object of this study is the theory and practice of adaptive physical activity for people with intellectual disability. It focuses on the concepts, paths, and applications of adaptive physical activities for young people with…
- Trial name
- NCT06444659
- Testing
- Adaptive Physical Activity Classes
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Hunan Normal University
Parkinson's Disease, Pathophysiology of Neuronal Oscillations Within Subthalamo-cortical Loops
Pathophysiology of Neuronal Oscillations Within Subthalamo-cortical Loops in Parkinson's Disease
Neuronal activity in circuits between the basal ganglia (BG) and motor cortical areas is abnormally synchronised and rhythmic. The oscillatory activity prevails at 8-30 Hz in untreated Parkinson's Disease (PD) and its amplitude…
- Trial name
- NCT01284686
- Testing
- subthalamo-cortical loops stimulation in a one-sided and bipolar way
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Parkinson's Disease
Tele-diagnostics for Remote Parkinson's Monitoring
The purpose of this research study is to design, implement, and clinically assess a portable, user worn system for monitoring Parkinson's disease (PD) motor symptoms.
- Trial name
- NCT01356056
- Testing
- Kinesia HomeView
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Great Lakes NeuroTechnologies Inc.
Parkinson's Disease
The Effectiveness of Motor-motor and Motor-cognitive Dual-task Training Interventions on Balance in People With Parkinson's Disease: a Feasibility Study
This study aims to test the feasibility and acceptability of home-based motor-motor dual-task training and motor-cognitive dual-task training interventions, and balance-related outcome measures which may be used in an anticipated…
- Trial name
- NCT05710588
- Testing
- motor-motor dual-task training, motor-cognitive dual-task training
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- University of Plymouth
Muscular Atrophy, Spinal
A Study to Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety When Given Before Symptoms Appear in Babies With Genetically Diagnosed Spinal Muscular Atrophy (SMA)
In this study, researchers will learn more about the effects and safety of BIIB115, also known as salanersen. Specifically, researchers will learn more about how salanersen works in babies who have been diagnosed with SMA through…
- Trial name
- STELLAR-1 (NCT07221669)
- Testing
- Salanersen
- Where
- 14 sites in United States, Australia and 5 more
- Volunteers
- 30 people
- Sponsor
- Biogen
Pediatric ALL, Adolescent
Pediatric Normative Markerless Movement Analysis
The objective of this project is to collect baseline data from a normative population of 20 children that gender and age matches the population of patients expected to be treated by Mary Bridge Children's Research \& Movement Lab.
- Trial name
- NCT06249880
- Testing
- Observation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- MultiCare Health System Research Institute
Parkinson Disease
Robotic Rehabilitation of Upper Limb in PD
It has been shown that robot-assisted therapy may be considered an effective and reliable method for the delivery of highly repetitive training useful to boost neuroplasticity.
- Trial name
- NCT03893786
- Testing
- Robotic Rehabilitation
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
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